| Beta cardiac myosin_1 |
| ID: | 1500510029 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 960 (918) | ||
| Sequences: | 4465 (2513) | ||
| Seq/Len: | 4.864 | ||
| Nf(neff/√len): | 82.9 |
HHblits Results: (2016_02)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 4.864).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 124_T | 187_N | 3.112 | 1.00 |
| 553_F | 563_F | 3.078 | 1.00 |
| 549_K | 590_I | 3.043 | 1.00 |
| 794_G | 798_R | 3.029 | 1.00 |
| 715_Y | 758_F | 3.023 | 1.00 |
| 518_Q | 522_D | 3.017 | 1.00 |
| 112_W | 129_K | 2.889 | 1.00 |
| 345_E | 442_R | 2.885 | 1.00 |
| 534_L | 548_F | 2.752 | 1.00 |
| 173_S | 665_T | 2.737 | 1.00 |
| 90_M | 104_N | 2.687 | 1.00 |
| 484_K | 525_E | 2.596 | 1.00 |
| 285_I | 332_T | 2.539 | 1.00 |
| 537_E | 551_K | 2.526 | 1.00 |
| 294_K | 297_L | 2.504 | 1.00 |
| 354_G | 358_H | 2.435 | 1.00 |
| 545_D | 592_G | 2.429 | 1.00 |
| 320_V | 323_I | 2.419 | 1.00 |
| 774_E | 777_R | 2.417 | 1.00 |
| 186_V | 189_K | 2.358 | 1.00 |
| 820_A | 824_V | 2.354 | 1.00 |
| 498_Q | 508_W | 2.335 | 1.00 |
| 815_Q | 819_R | 2.275 | 1.00 |
| 232_N | 240_N | 2.253 | 1.00 |
| 357_M | 361_N | 2.180 | 1.00 |
| 154_I | 187_N | 2.140 | 1.00 |
| 789_Q | 793_R | 2.136 | 1.00 |
| 117_Y | 156_S | 2.132 | 1.00 |
| 700_E | 703_R | 2.108 | 1.00 |
| 97_H | 100_A | 2.081 | 1.00 |
| 677_E | 688_L | 2.065 | 1.00 |
| 479_N | 483_E | 2.031 | 1.00 |
| 461_D | 464_G | 1.966 | 1.00 |
| 297_L | 333_D | 1.955 | 1.00 |
| 234_K | 239_D | 1.950 | 1.00 |
| 721_R | 774_E | 1.935 | 1.00 |
| 333_D | 350_Y | 1.888 | 1.00 |
| 337_D | 346_K | 1.870 | 1.00 |
| 580_I | 585_I | 1.851 | 1.00 |
| 311_A | 315_Q | 1.836 | 1.00 |
| 578_S | 587_D | 1.831 | 1.00 |
| 359_F | 362_M | 1.820 | 1.00 |
| 353_T | 356_I | 1.803 | 1.00 |
| 577_F | 581_H | 1.802 | 1.00 |
| 416_N | 419_Q | 1.787 | 1.00 |
| 231_G | 244_F | 1.786 | 1.00 |
| 478_I | 482_N | 1.774 | 1.00 |
| 312_F | 428_A | 1.768 | 1.00 |
| 161_A | 174_I | 1.768 | 1.00 |
| 180_S | 184_K | 1.767 | 1.00 |
| 281_R | 325_D | 1.766 | 1.00 |
| 433_E | 437_N | 1.744 | 1.00 |
| 473_F | 477_C | 1.744 | 1.00 |
| 537_E | 541_P | 1.732 | 1.00 |
| 269_E | 272_R | 1.731 | 1.00 |
| 355_A | 388_M | 1.728 | 1.00 |
| 336_F | 349_M | 1.725 | 1.00 |
| 346_K | 350_Y | 1.711 | 1.00 |
| 342_T | 345_E | 1.697 | 0.99 |
| 678_T | 683_V | 1.664 | 0.99 |
| 288_Q | 332_T | 1.662 | 0.99 |
| 240_N | 243_R | 1.659 | 0.99 |
| 180_S | 185_T | 1.655 | 0.99 |
| 228_E | 232_N | 1.640 | 0.99 |
| 583_A | 586_V | 1.639 | 0.99 |
| 280_E | 284_H | 1.627 | 0.99 |
| 228_E | 240_N | 1.623 | 0.99 |
| 505_G | 760_H | 1.619 | 0.99 |
| 479_N | 482_N | 1.618 | 0.99 |
| 289_I | 293_K | 1.610 | 0.99 |
| 324_D | 327_E | 1.609 | 0.99 |
| 500_E | 762_K | 1.609 | 0.99 |
| 475_Q | 478_I | 1.608 | 0.99 |
| 390_L | 395_L | 1.605 | 0.99 |
| 235_T | 238_N | 1.604 | 0.99 |
| 235_T | 243_R | 1.602 | 0.99 |
| 341_F | 346_K | 1.600 | 0.99 |
| 385_A | 395_L | 1.591 | 0.99 |
| 292_N | 298_L | 1.587 | 0.99 |
| 238_N | 243_R | 1.583 | 0.99 |
| 475_Q | 483_E | 1.576 | 0.99 |
| 232_N | 235_T | 1.574 | 0.99 |
| 306_N | 309_D | 1.569 | 0.99 |
| 696_N | 701_G | 1.566 | 0.99 |
| 544_T | 594_L | 1.562 | 0.99 |
| 312_F | 360_G | 1.555 | 0.99 |
| 533_I | 536_E | 1.553 | 0.99 |
| 276_Q | 282_D | 1.544 | 0.99 |
| 478_I | 483_E | 1.543 | 0.99 |
| 232_N | 244_F | 1.541 | 0.99 |
| 581_H | 588_Y | 1.539 | 0.99 |
| 737_D | 740_K | 1.530 | 0.99 |
| 349_M | 435_M | 1.528 | 0.99 |
| 333_D | 346_K | 1.525 | 0.99 |
| 695_C | 705_C | 1.516 | 0.99 |
| 798_R | 802_K | 1.510 | 0.98 |
| 596_K | 599_D | 1.508 | 0.98 |
| 588_Y | 597_N | 1.507 | 0.98 |
| 537_E | 547_T | 1.499 | 0.98 |
| 382_D | 392_S | 1.499 | 0.98 |
| 178_G | 184_K | 1.498 | 0.98 |
| 300_M | 347_N | 1.498 | 0.98 |
| 159_D | 163_Q | 1.495 | 0.98 |
| 471_N | 482_N | 1.494 | 0.98 |
| 479_N | 486_Q | 1.493 | 0.98 |
| 543_A | 547_T | 1.488 | 0.98 |
| 474_E | 486_Q | 1.487 | 0.98 |
| 159_D | 194_Y | 1.487 | 0.98 |
| 478_I | 485_L | 1.472 | 0.98 |
| 181_G | 185_T | 1.472 | 0.98 |
| 461_D | 465_F | 1.472 | 0.98 |
| 391_N | 394_D | 1.470 | 0.98 |
| 461_D | 466_E | 1.470 | 0.98 |
| 490_N | 494_F | 1.468 | 0.98 |
| 765_F | 768_G | 1.467 | 0.98 |
| 310_Y | 361_N | 1.465 | 0.98 |
| 616_L | 620_L | 1.459 | 0.98 |
| 605_V | 609_Y | 1.457 | 0.98 |
| 247_F | 458_G | 1.453 | 0.98 |
| 178_G | 183_G | 1.453 | 0.98 |
| 547_T | 551_K | 1.452 | 0.98 |
| 684_M | 689_V | 1.445 | 0.98 |
| 700_E | 704_I | 1.440 | 0.98 |
| 182_A | 185_T | 1.439 | 0.98 |
| 192_I | 250_I | 1.438 | 0.98 |
| 180_S | 183_G | 1.438 | 0.98 |
| 501_Y | 504_E | 1.438 | 0.98 |
| 593_W | 597_N | 1.437 | 0.98 |
| 442_R | 445_A | 1.435 | 0.98 |
| 673_I | 689_V | 1.434 | 0.98 |
| 118_S | 121_F | 1.434 | 0.98 |
| 499_E | 503_K | 1.433 | 0.98 |
| 474_E | 478_I | 1.433 | 0.98 |
| 181_G | 184_K | 1.429 | 0.98 |
| 680_S | 683_V | 1.426 | 0.98 |
| 530_I | 548_F | 1.426 | 0.98 |
| 487_Q | 495_V | 1.422 | 0.98 |
| 578_S | 585_I | 1.417 | 0.97 |
| 274_I | 429_K | 1.416 | 0.97 |
| 530_I | 552_L | 1.410 | 0.97 |
| 249_R | 264_E | 1.410 | 0.97 |
| 475_Q | 482_N | 1.409 | 0.97 |
| 281_R | 284_H | 1.408 | 0.97 |
| 672_C | 676_N | 1.404 | 0.97 |
| 293_K | 298_L | 1.404 | 0.97 |
| 808_R | 812_L | 1.403 | 0.97 |
| 356_I | 428_A | 1.400 | 0.97 |
| 238_N | 242_S | 1.396 | 0.97 |
| 304_T | 309_D | 1.394 | 0.97 |
| 380_E | 384_S | 1.392 | 0.97 |
| 471_N | 475_Q | 1.390 | 0.97 |
| 179_E | 184_K | 1.389 | 0.97 |
| 489_F | 501_Y | 1.386 | 0.97 |
| 768_G | 771_G | 1.377 | 0.97 |
| 267_L | 270_K | 1.376 | 0.97 |
| 231_G | 240_N | 1.374 | 0.97 |
| 284_H | 287_Y | 1.373 | 0.97 |
| 178_G | 181_G | 1.373 | 0.97 |
| 232_N | 238_N | 1.369 | 0.97 |
| 577_F | 583_A | 1.369 | 0.97 |
| 478_I | 486_Q | 1.361 | 0.97 |
| 86_K | 104_N | 1.358 | 0.97 |
| 483_E | 486_Q | 1.356 | 0.96 |
| 537_E | 543_A | 1.349 | 0.96 |
| 479_N | 485_L | 1.344 | 0.96 |
| 795_V | 799_M | 1.342 | 0.96 |
| 179_E | 185_T | 1.341 | 0.96 |
| 224_N | 228_E | 1.340 | 0.96 |
| 280_E | 287_Y | 1.340 | 0.96 |
| 474_E | 483_E | 1.339 | 0.96 |
| 240_N | 244_F | 1.336 | 0.96 |
| 389_G | 613_S | 1.336 | 0.96 |
| 337_D | 343_S | 1.334 | 0.96 |
| 462_I | 466_E | 1.334 | 0.96 |
| 154_I | 670_V | 1.333 | 0.96 |
| 217_E | 221_I | 1.330 | 0.96 |
| 791_Q | 794_G | 1.328 | 0.96 |
| 548_F | 552_L | 1.328 | 0.96 |
| 541_P | 547_T | 1.326 | 0.96 |
| 224_N | 237_R | 1.325 | 0.96 |
| 740_K | 743_E | 1.323 | 0.96 |
| 186_V | 190_R | 1.317 | 0.96 |
| 302_L | 386_Y | 1.313 | 0.96 |
| 488_F | 669_F | 1.312 | 0.96 |
| 417_V | 421_I | 1.308 | 0.95 |
| 689_V | 692_Q | 1.308 | 0.95 |
| 343_S | 347_N | 1.308 | 0.95 |
| 179_E | 182_A | 1.306 | 0.95 |
| 484_K | 487_Q | 1.301 | 0.95 |
| 577_F | 582_Y | 1.300 | 0.95 |
| 226_A | 332_T | 1.299 | 0.95 |
| 817_N | 820_A | 1.299 | 0.95 |
| 462_I | 465_F | 1.299 | 0.95 |
| 475_Q | 486_Q | 1.298 | 0.95 |
| 472_S | 596_K | 1.297 | 0.95 |
| 240_N | 246_K | 1.297 | 0.95 |
| 250_I | 258_L | 1.293 | 0.95 |
| 812_L | 816_W | 1.292 | 0.95 |
| 432_Y | 436_F | 1.285 | 0.95 |
| 547_T | 594_L | 1.284 | 0.95 |
| 103_Y | 106_K | 1.284 | 0.95 |
| 178_G | 185_T | 1.283 | 0.95 |
| 480_F | 525_E | 1.282 | 0.95 |
| 796_L | 800_E | 1.276 | 0.95 |
| 235_T | 240_N | 1.274 | 0.94 |
| 466_E | 475_Q | 1.274 | 0.94 |
| 777_R | 781_L | 1.272 | 0.94 |
| 693_L | 698_V | 1.272 | 0.94 |
| 492_H | 496_L | 1.271 | 0.94 |
| 471_N | 479_N | 1.271 | 0.94 |
| 818_I | 822_M | 1.270 | 0.94 |
| 919_V | 922_M | 1.268 | 0.94 |
| 462_I | 468_F | 1.267 | 0.94 |
| 517_L | 521_I | 1.265 | 0.94 |
| 466_E | 471_N | 1.264 | 0.94 |
| 355_A | 384_S | 1.263 | 0.94 |
| 474_E | 479_N | 1.260 | 0.94 |
| 420_V | 424_T | 1.260 | 0.94 |
| 860_K | 864_E | 1.255 | 0.94 |
| 425_G | 428_A | 1.252 | 0.94 |
| 532_S | 652_R | 1.252 | 0.94 |
| 249_R | 262_D | 1.250 | 0.94 |
| 233_A | 238_N | 1.245 | 0.94 |
| 233_A | 243_R | 1.242 | 0.93 |
| 540_F | 547_T | 1.242 | 0.93 |
| 381_A | 384_S | 1.242 | 0.93 |
| 357_M | 360_G | 1.241 | 0.93 |
| 497_E | 501_Y | 1.239 | 0.93 |
| 498_Q | 501_Y | 1.239 | 0.93 |
| 159_D | 165_M | 1.235 | 0.93 |
| 106_K | 686_N | 1.235 | 0.93 |
| 476_L | 479_N | 1.235 | 0.93 |
| 436_F | 440_V | 1.233 | 0.93 |
| 581_H | 584_G | 1.231 | 0.93 |
| 500_E | 508_W | 1.230 | 0.93 |
| 152_P | 155_F | 1.230 | 0.93 |
| 475_Q | 479_N | 1.229 | 0.93 |
| 811_L | 815_Q | 1.228 | 0.93 |
| 485_L | 489_F | 1.227 | 0.93 |
| 540_F | 543_A | 1.225 | 0.93 |
| 501_Y | 508_W | 1.224 | 0.93 |
| 228_E | 231_G | 1.221 | 0.93 |
| 695_C | 701_G | 1.220 | 0.93 |
| 229_A | 288_Q | 1.220 | 0.93 |
| 486_Q | 489_F | 1.219 | 0.93 |
| 460_L | 466_E | 1.218 | 0.93 |
| 773_L | 777_R | 1.216 | 0.93 |
| 746_L | 763_V | 1.211 | 0.92 |
| 465_F | 468_F | 1.210 | 0.92 |
| 115_Y | 124_T | 1.210 | 0.92 |
| 116_T | 119_G | 1.209 | 0.92 |
| 351_K | 614_L | 1.207 | 0.92 |
| 703_R | 706_R | 1.206 | 0.92 |
| 814_I | 818_I | 1.206 | 0.92 |
| 676_N | 679_K | 1.199 | 0.92 |
| 581_H | 586_V | 1.198 | 0.92 |
| 482_N | 486_Q | 1.197 | 0.92 |
| 153_H | 162_Y | 1.196 | 0.92 |
| 328_E | 331_A | 1.195 | 0.92 |
| 266_Y | 269_E | 1.195 | 0.92 |
| 463_A | 466_E | 1.192 | 0.92 |
| 709_F | 757_K | 1.192 | 0.92 |
| 540_F | 594_L | 1.190 | 0.91 |
| 238_N | 241_S | 1.188 | 0.91 |
| 348_S | 614_L | 1.186 | 0.91 |
| 152_P | 158_S | 1.186 | 0.91 |
| 516_D | 521_I | 1.185 | 0.91 |
| 576_H | 589_N | 1.184 | 0.91 |
| 310_Y | 358_H | 1.180 | 0.91 |
| 530_I | 579_L | 1.179 | 0.91 |
| 105_L | 125_V | 1.179 | 0.91 |
| 258_L | 261_A | 1.178 | 0.91 |
| 673_I | 676_N | 1.178 | 0.91 |
| 537_E | 544_T | 1.176 | 0.91 |
| 233_A | 240_N | 1.176 | 0.91 |
| 426_A | 429_K | 1.175 | 0.91 |
| 476_L | 483_E | 1.174 | 0.91 |
| 400_C | 415_Q | 1.173 | 0.91 |
| 152_P | 156_S | 1.172 | 0.91 |
| 475_Q | 485_L | 1.170 | 0.90 |
| 108_R | 115_Y | 1.170 | 0.90 |
| 281_R | 287_Y | 1.169 | 0.90 |
| 312_F | 425_G | 1.168 | 0.90 |
| 232_N | 243_R | 1.166 | 0.90 |
| 179_E | 186_V | 1.165 | 0.90 |
| 280_E | 283_Y | 1.165 | 0.90 |
| 355_A | 387_L | 1.165 | 0.90 |
| 669_F | 672_C | 1.163 | 0.90 |
| 231_G | 235_T | 1.163 | 0.90 |
| 108_R | 116_T | 1.161 | 0.90 |
| 540_F | 544_T | 1.160 | 0.90 |
| 811_L | 814_I | 1.159 | 0.90 |
| 233_A | 241_S | 1.157 | 0.90 |
| 232_N | 241_S | 1.156 | 0.90 |
| 142_Y | 153_H | 1.155 | 0.90 |
| 543_A | 551_K | 1.154 | 0.90 |
| 153_H | 161_A | 1.154 | 0.90 |
| 341_F | 345_E | 1.154 | 0.90 |
| 89_D | 93_L | 1.152 | 0.90 |
| 714_L | 717_D | 1.151 | 0.90 |
| 270_K | 599_D | 1.150 | 0.89 |
| 708_G | 712_R | 1.150 | 0.89 |
| 192_I | 196_A | 1.149 | 0.89 |
| 745_L | 749_L | 1.148 | 0.89 |
| 180_S | 189_K | 1.147 | 0.89 |
| 231_G | 436_F | 1.144 | 0.89 |
| 739_R | 743_E | 1.143 | 0.89 |
| 145_K | 149_E | 1.142 | 0.89 |
| 431_V | 617_L | 1.141 | 0.89 |
| 812_L | 815_Q | 1.140 | 0.89 |
| 310_Y | 313_I | 1.140 | 0.89 |
| 477_C | 483_E | 1.138 | 0.89 |
| 693_L | 696_N | 1.136 | 0.89 |
| 548_F | 590_I | 1.132 | 0.88 |
| 818_I | 821_F | 1.131 | 0.88 |
| 108_R | 114_I | 1.130 | 0.88 |
| 697_G | 704_I | 1.129 | 0.88 |
| 711_N | 768_G | 1.127 | 0.88 |
| 153_H | 158_S | 1.125 | 0.88 |
| 701_G | 704_I | 1.125 | 0.88 |
| 302_L | 383_K | 1.123 | 0.88 |
| 231_G | 243_R | 1.121 | 0.88 |
| 186_V | 227_L | 1.121 | 0.88 |
| 162_Y | 165_M | 1.121 | 0.88 |
| 478_I | 489_F | 1.119 | 0.88 |
| 657_K | 660_T | 1.118 | 0.88 |
| 165_M | 252_F | 1.117 | 0.88 |
| 116_T | 127_P | 1.117 | 0.88 |
| 458_G | 462_I | 1.117 | 0.88 |
| 489_F | 497_E | 1.117 | 0.88 |
| 240_N | 284_H | 1.116 | 0.88 |
| 155_F | 193_Q | 1.114 | 0.87 |
| 482_N | 485_L | 1.113 | 0.87 |
| 793_R | 797_A | 1.112 | 0.87 |
| 460_L | 465_F | 1.112 | 0.87 |
| 672_C | 675_P | 1.111 | 0.87 |
| 480_F | 485_L | 1.111 | 0.87 |
| 105_L | 108_R | 1.110 | 0.87 |
| 541_P | 544_T | 1.109 | 0.87 |
| 165_M | 172_Q | 1.108 | 0.87 |
| 336_F | 341_F | 1.107 | 0.87 |
| 272_R | 280_E | 1.107 | 0.87 |
| 460_L | 464_G | 1.106 | 0.87 |
| 424_T | 428_A | 1.105 | 0.87 |
| 698_V | 701_G | 1.105 | 0.87 |
| 492_H | 667_P | 1.104 | 0.87 |
| 765_F | 770_L | 1.102 | 0.87 |
| 536_E | 540_F | 1.101 | 0.87 |
| 595_Q | 599_D | 1.100 | 0.86 |
| 486_Q | 490_N | 1.100 | 0.86 |
| 172_Q | 176_I | 1.099 | 0.86 |
| 377_G | 381_A | 1.099 | 0.86 |
| 358_H | 380_E | 1.099 | 0.86 |
| 241_S | 244_F | 1.098 | 0.86 |
| 533_I | 537_E | 1.098 | 0.86 |
| 696_N | 705_C | 1.098 | 0.86 |
| 786_T | 790_A | 1.095 | 0.86 |
| 759_G | 764_F | 1.095 | 0.86 |
| 490_N | 497_E | 1.095 | 0.86 |
| 617_L | 620_L | 1.094 | 0.86 |
| 228_E | 246_K | 1.094 | 0.86 |
| 472_S | 475_Q | 1.092 | 0.86 |
| 490_N | 493_M | 1.091 | 0.86 |
| 480_F | 483_E | 1.090 | 0.86 |
| 397_K | 412_T | 1.089 | 0.86 |
| 234_K | 237_R | 1.089 | 0.86 |
| 463_A | 467_I | 1.084 | 0.85 |
| 435_M | 438_W | 1.083 | 0.85 |
| 669_F | 676_N | 1.083 | 0.85 |
| 592_G | 595_Q | 1.082 | 0.85 |
| 471_N | 474_E | 1.082 | 0.85 |
| 280_E | 286_F | 1.080 | 0.85 |
| 471_N | 478_I | 1.079 | 0.85 |
| 235_T | 241_S | 1.074 | 0.85 |
| 159_D | 198_I | 1.074 | 0.85 |
| 88_E | 113_M | 1.074 | 0.85 |
| 323_I | 328_E | 1.073 | 0.85 |
| 283_Y | 287_Y | 1.072 | 0.85 |
| 178_G | 182_A | 1.071 | 0.84 |
| 420_V | 425_G | 1.071 | 0.84 |
| 468_F | 471_N | 1.070 | 0.84 |
| 404_V | 413_K | 1.069 | 0.84 |
| 495_V | 518_Q | 1.069 | 0.84 |
| 609_Y | 612_S | 1.068 | 0.84 |
| 491_H | 495_V | 1.067 | 0.84 |
| 488_F | 492_H | 1.066 | 0.84 |
| 474_E | 485_L | 1.065 | 0.84 |
| 289_I | 353_T | 1.064 | 0.84 |
| 743_E | 747_S | 1.064 | 0.84 |
| 237_R | 240_N | 1.064 | 0.84 |
| 231_G | 242_S | 1.064 | 0.84 |
| 564_Q | 585_I | 1.064 | 0.84 |
| 813_V | 816_W | 1.062 | 0.84 |
| 93_L | 96_L | 1.061 | 0.84 |
| 176_I | 182_A | 1.060 | 0.84 |
| 697_G | 700_E | 1.060 | 0.84 |
| 790_A | 794_G | 1.058 | 0.83 |
| 785_I | 788_I | 1.058 | 0.83 |
| 816_W | 820_A | 1.057 | 0.83 |
| 143_R | 159_D | 1.056 | 0.83 |
| 671_R | 676_N | 1.056 | 0.83 |
| 474_E | 489_F | 1.053 | 0.83 |
| 86_K | 90_M | 1.052 | 0.83 |
| 389_G | 614_L | 1.051 | 0.83 |
| 224_N | 232_N | 1.050 | 0.83 |
| 705_C | 710_P | 1.050 | 0.83 |
| 230_F | 243_R | 1.049 | 0.83 |
| 291_S | 325_D | 1.049 | 0.83 |
| 647_V | 651_H | 1.048 | 0.83 |
| 179_E | 183_G | 1.048 | 0.83 |
| 233_A | 244_F | 1.047 | 0.83 |
| 529_G | 534_L | 1.044 | 0.82 |
| 293_K | 297_L | 1.043 | 0.82 |
| 185_T | 189_K | 1.042 | 0.82 |
| 695_C | 706_R | 1.041 | 0.82 |
| 41_D | 47_V | 1.038 | 0.82 |
| 655_L | 659_M | 1.037 | 0.82 |
| 480_F | 487_Q | 1.033 | 0.81 |
| 692_Q | 697_G | 1.033 | 0.81 |
| 542_K | 594_L | 1.032 | 0.81 |
| 106_K | 110_G | 1.032 | 0.81 |
| 925_R | 929_E | 1.031 | 0.81 |
| 693_L | 701_G | 1.029 | 0.81 |
| 829_W | 832_L | 1.029 | 0.81 |
| 98_E | 694_R | 1.029 | 0.81 |
| 688_L | 706_R | 1.028 | 0.81 |
| 792_S | 796_L | 1.027 | 0.81 |
| 190_R | 193_Q | 1.027 | 0.81 |
| 473_F | 648_S | 1.027 | 0.81 |
| 494_F | 497_E | 1.026 | 0.81 |
| 248_I | 263_I | 1.026 | 0.81 |
| 655_L | 658_L | 1.025 | 0.81 |
| 358_H | 383_K | 1.024 | 0.81 |
| 432_Y | 444_N | 1.021 | 0.80 |
| 788_I | 791_Q | 1.020 | 0.80 |
| 268_L | 272_R | 1.018 | 0.80 |
| 490_N | 513_F | 1.016 | 0.80 |
| 814_I | 817_N | 1.015 | 0.80 |
| 497_E | 508_W | 1.014 | 0.80 |
| 52_V | 62_E | 1.014 | 0.80 |
| 861_E | 865_K | 1.014 | 0.80 |
| 564_Q | 580_I | 1.013 | 0.80 |
| 519_A | 562_N | 1.012 | 0.80 |
| 440_V | 444_N | 1.012 | 0.80 |
| 188_T | 192_I | 1.012 | 0.80 |
| 87_I | 93_L | 1.011 | 0.79 |
| 157_I | 161_A | 1.011 | 0.79 |
| 187_N | 192_I | 1.011 | 0.79 |
| 500_E | 503_K | 1.010 | 0.79 |
| 842_S | 846_E | 1.009 | 0.79 |
| 228_E | 244_F | 1.009 | 0.79 |
| 473_F | 483_E | 1.008 | 0.79 |
| 221_I | 224_N | 1.008 | 0.79 |
| 179_E | 189_K | 1.007 | 0.79 |
| 119_G | 127_P | 1.007 | 0.79 |
| 780_R | 783_R | 1.006 | 0.79 |
| 517_L | 523_L | 1.006 | 0.79 |
| 907_Q | 911_N | 1.004 | 0.79 |
| 521_I | 524_I | 1.004 | 0.79 |
| 544_T | 547_T | 1.004 | 0.79 |
| 191_V | 250_I | 1.004 | 0.79 |
| 266_Y | 270_K | 1.003 | 0.79 |
| 786_T | 789_Q | 1.002 | 0.79 |
| 799_M | 802_K | 1.002 | 0.79 |
| 866_S | 870_R | 1.002 | 0.79 |
| 91_A | 100_A | 1.000 | 0.78 |
| 294_K | 333_D | 1.000 | 0.78 |
| 514_G | 517_L | 1.000 | 0.78 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 1i84S | 2 | 0.9313 | 100 | -0.014 | Contact Map |
| 1kk8A | 1 | 0.8229 | 100 | 0.013 | Contact Map |
| 2dfsA | 2 | 0.8802 | 100 | 0.042 | Contact Map |
| 4pa0A | 2 | 0 | 100 | 0.058 | Contact Map |
| 4qbdA | 2 | 0.8187 | 100 | 0.063 | Contact Map |
| 2ycuA | 1 | 0.9375 | 100 | 0.08 | Contact Map |
| 1g8xA | 2 | 0.9729 | 100 | 0.081 | Contact Map |
| 1w7jA | 1 | 0.7719 | 100 | 0.092 | Contact Map |
| 1w9iA | 1 | 0.725 | 100 | 0.101 | Contact Map |
| 4anjA | 1 | 0.8698 | 100 | 0.103 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)