| MalT180717 |
| ID: | 1500375853 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 901 (879) | ||
| Sequences: | 4910 (3710.2) | ||
| Seq/Len: | 5.586 | ||
| Nf(neff/√len): | 125.1 |
HHblits Results: (2016_02)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 5.586).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 665_D | 668_A | 7.681 | 1.00 |
| 585_R | 588_E | 7.233 | 1.00 |
| 344_H | 363_H | 6.260 | 1.00 |
| 624_D | 627_N | 5.772 | 1.00 |
| 49_I | 158_L | 5.515 | 1.00 |
| 543_F | 546_T | 5.221 | 1.00 |
| 703_E | 706_P | 4.518 | 1.00 |
| 191_A | 222_L | 4.305 | 1.00 |
| 464_N | 467_E | 4.305 | 1.00 |
| 424_R | 427_E | 3.764 | 1.00 |
| 503_E | 506_R | 3.479 | 1.00 |
| 187_T | 190_E | 3.328 | 1.00 |
| 839_R | 842_Q | 3.261 | 1.00 |
| 851_Y | 859_E | 3.259 | 1.00 |
| 590_E | 622_R | 3.243 | 1.00 |
| 871_I | 875_Y | 3.236 | 1.00 |
| 629_R | 663_T | 3.201 | 1.00 |
| 847_I | 856_I | 3.162 | 1.00 |
| 130_Y | 157_V | 3.127 | 1.00 |
| 743_R | 746_D | 3.126 | 1.00 |
| 277_L | 347_A | 3.111 | 1.00 |
| 548_W | 552_E | 2.916 | 1.00 |
| 274_S | 320_Y | 2.905 | 1.00 |
| 53_A | 126_V | 2.867 | 1.00 |
| 49_I | 126_V | 2.844 | 1.00 |
| 580_L | 588_E | 2.810 | 1.00 |
| 552_E | 576_R | 2.805 | 1.00 |
| 267_T | 300_E | 2.794 | 1.00 |
| 548_W | 583_W | 2.793 | 1.00 |
| 264_D | 300_E | 2.786 | 1.00 |
| 188_H | 209_S | 2.783 | 1.00 |
| 535_S | 551_Q | 2.734 | 1.00 |
| 39_S | 43_Y | 2.709 | 1.00 |
| 195_F | 226_A | 2.667 | 1.00 |
| 27_S | 55_G | 2.630 | 1.00 |
| 47_T | 51_Q | 2.624 | 1.00 |
| 348_A | 364_A | 2.595 | 1.00 |
| 841_W | 845_G | 2.555 | 1.00 |
| 37_I | 49_I | 2.537 | 1.00 |
| 50_S | 61_W | 2.525 | 1.00 |
| 191_A | 212_C | 2.468 | 1.00 |
| 352_M | 372_M | 2.455 | 1.00 |
| 58_D | 121_S | 2.437 | 1.00 |
| 128_D | 158_L | 2.433 | 1.00 |
| 26_L | 52_W | 2.410 | 1.00 |
| 840_E | 877_K | 2.399 | 1.00 |
| 264_D | 267_T | 2.382 | 1.00 |
| 211_I | 222_L | 2.375 | 1.00 |
| 41_A | 160_R | 2.371 | 1.00 |
| 844_L | 874_L | 2.289 | 1.00 |
| 16_T | 47_T | 2.277 | 1.00 |
| 577_A | 593_A | 2.268 | 1.00 |
| 22_L | 48_L | 2.228 | 1.00 |
| 580_L | 592_S | 2.226 | 1.00 |
| 587_D | 622_R | 2.221 | 1.00 |
| 325_G | 329_R | 2.210 | 1.00 |
| 660_W | 665_D | 2.200 | 1.00 |
| 619_S | 627_N | 2.178 | 1.00 |
| 580_L | 585_R | 2.176 | 1.00 |
| 51_Q | 54_A | 2.117 | 1.00 |
| 590_E | 615_L | 2.113 | 1.00 |
| 712_E | 734_L | 2.110 | 1.00 |
| 268_R | 272_L | 2.019 | 1.00 |
| 576_R | 592_S | 1.994 | 1.00 |
| 26_L | 35_A | 1.976 | 1.00 |
| 224_L | 259_V | 1.963 | 1.00 |
| 545_Q | 583_W | 1.943 | 1.00 |
| 275_A | 329_R | 1.941 | 1.00 |
| 865_T | 872_R | 1.939 | 1.00 |
| 345_R | 349_E | 1.916 | 1.00 |
| 252_S | 330_Q | 1.915 | 1.00 |
| 559_N | 595_S | 1.911 | 1.00 |
| 660_W | 668_A | 1.911 | 1.00 |
| 190_E | 193_Q | 1.904 | 1.00 |
| 272_L | 339_E | 1.902 | 1.00 |
| 862_V | 867_I | 1.897 | 1.00 |
| 267_T | 301_I | 1.894 | 1.00 |
| 192_K | 208_S | 1.856 | 1.00 |
| 719_R | 753_D | 1.848 | 1.00 |
| 627_N | 631_Q | 1.839 | 1.00 |
| 619_S | 631_Q | 1.838 | 1.00 |
| 847_I | 871_I | 1.837 | 1.00 |
| 594_R | 615_L | 1.830 | 1.00 |
| 193_Q | 197_C | 1.820 | 1.00 |
| 538_L | 543_F | 1.809 | 1.00 |
| 548_W | 576_R | 1.802 | 1.00 |
| 209_S | 213_D | 1.801 | 1.00 |
| 657_V | 673_L | 1.796 | 1.00 |
| 698_Q | 703_E | 1.785 | 1.00 |
| 715_N | 734_L | 1.783 | 1.00 |
| 288_V | 350_S | 1.780 | 1.00 |
| 854_E | 858_G | 1.780 | 1.00 |
| 619_S | 624_D | 1.778 | 1.00 |
| 270_F | 297_R | 1.768 | 1.00 |
| 265_L | 268_R | 1.766 | 1.00 |
| 593_A | 618_C | 1.760 | 1.00 |
| 573_V | 595_S | 1.749 | 1.00 |
| 276_I | 329_R | 1.743 | 1.00 |
| 548_W | 580_L | 1.743 | 1.00 |
| 188_H | 212_C | 1.741 | 1.00 |
| 276_I | 343_I | 1.733 | 1.00 |
| 19_R | 22_L | 1.731 | 1.00 |
| 875_Y | 880_V | 1.727 | 1.00 |
| 495_G | 511_M | 1.717 | 1.00 |
| 508_L | 512_Q | 1.715 | 1.00 |
| 844_L | 890_A | 1.705 | 1.00 |
| 849_S | 859_E | 1.699 | 1.00 |
| 130_Y | 139_H | 1.686 | 1.00 |
| 345_R | 369_D | 1.678 | 1.00 |
| 46_T | 50_S | 1.674 | 1.00 |
| 52_W | 156_V | 1.672 | 1.00 |
| 590_E | 594_R | 1.670 | 1.00 |
| 171_R | 178_E | 1.664 | 1.00 |
| 618_C | 622_R | 1.662 | 1.00 |
| 844_L | 886_A | 1.649 | 1.00 |
| 277_L | 288_V | 1.645 | 1.00 |
| 855_Q | 858_G | 1.638 | 0.99 |
| 538_L | 546_T | 1.633 | 0.99 |
| 329_R | 340_L | 1.632 | 0.99 |
| 271_L | 301_I | 1.631 | 0.99 |
| 728_N | 754_A | 1.626 | 0.99 |
| 708_E | 741_A | 1.624 | 0.99 |
| 269_H | 339_E | 1.620 | 0.99 |
| 271_L | 328_L | 1.619 | 0.99 |
| 625_L | 663_T | 1.616 | 0.99 |
| 589_A | 618_C | 1.609 | 0.99 |
| 881_A | 885_D | 1.607 | 0.99 |
| 869_T | 873_N | 1.602 | 0.99 |
| 847_I | 853_N | 1.600 | 0.99 |
| 731_L | 753_D | 1.597 | 0.99 |
| 125_L | 155_L | 1.596 | 0.99 |
| 75_A | 78_L | 1.591 | 0.99 |
| 43_Y | 219_A | 1.578 | 0.99 |
| 49_I | 53_A | 1.576 | 0.99 |
| 852_S | 855_Q | 1.560 | 0.99 |
| 555_F | 576_R | 1.545 | 0.99 |
| 389_E | 392_L | 1.545 | 0.99 |
| 419_M | 431_L | 1.528 | 0.99 |
| 204_E | 207_E | 1.528 | 0.99 |
| 735_N | 754_A | 1.527 | 0.99 |
| 854_E | 864_A | 1.524 | 0.99 |
| 276_I | 347_A | 1.523 | 0.99 |
| 735_N | 751_L | 1.520 | 0.99 |
| 415_Q | 419_M | 1.520 | 0.99 |
| 577_A | 589_A | 1.512 | 0.99 |
| 576_R | 580_L | 1.507 | 0.99 |
| 629_R | 633_N | 1.500 | 0.99 |
| 186_F | 194_F | 1.498 | 0.99 |
| 51_Q | 55_G | 1.494 | 0.99 |
| 627_N | 630_S | 1.493 | 0.99 |
| 332_C | 343_I | 1.474 | 0.99 |
| 149_Q | 153_L | 1.473 | 0.99 |
| 653_N | 672_W | 1.468 | 0.99 |
| 547_A | 579_L | 1.465 | 0.99 |
| 284_L | 350_S | 1.458 | 0.99 |
| 660_W | 672_W | 1.455 | 0.98 |
| 40_P | 43_Y | 1.447 | 0.98 |
| 37_I | 158_L | 1.444 | 0.98 |
| 27_S | 52_W | 1.444 | 0.98 |
| 393_L | 396_S | 1.442 | 0.98 |
| 53_A | 124_Y | 1.438 | 0.98 |
| 58_D | 123_L | 1.437 | 0.98 |
| 854_E | 869_T | 1.432 | 0.98 |
| 853_N | 868_K | 1.430 | 0.98 |
| 429_N | 433_A | 1.429 | 0.98 |
| 698_Q | 706_P | 1.428 | 0.98 |
| 160_R | 321_H | 1.424 | 0.98 |
| 731_L | 750_V | 1.423 | 0.98 |
| 738_Y | 750_V | 1.422 | 0.98 |
| 49_I | 156_V | 1.421 | 0.98 |
| 419_M | 427_E | 1.416 | 0.98 |
| 573_V | 592_S | 1.411 | 0.98 |
| 35_A | 154_T | 1.408 | 0.98 |
| 853_N | 875_Y | 1.396 | 0.98 |
| 667_A | 701_L | 1.389 | 0.98 |
| 748_Q | 752_L | 1.384 | 0.98 |
| 708_E | 712_E | 1.383 | 0.98 |
| 128_D | 131_H | 1.381 | 0.98 |
| 579_L | 583_W | 1.378 | 0.98 |
| 626_D | 663_T | 1.378 | 0.98 |
| 342_E | 346_A | 1.374 | 0.98 |
| 307_F | 324_F | 1.370 | 0.98 |
| 844_L | 847_I | 1.365 | 0.97 |
| 25_K | 183_Q | 1.365 | 0.97 |
| 34_L | 146_I | 1.363 | 0.97 |
| 844_L | 880_V | 1.360 | 0.97 |
| 843_V | 870_H | 1.358 | 0.97 |
| 287_R | 353_A | 1.357 | 0.97 |
| 159_S | 163_P | 1.357 | 0.97 |
| 36_L | 159_S | 1.355 | 0.97 |
| 548_W | 579_L | 1.352 | 0.97 |
| 588_E | 591_A | 1.351 | 0.97 |
| 416_A | 435_A | 1.350 | 0.97 |
| 590_E | 619_S | 1.347 | 0.97 |
| 273_K | 347_A | 1.345 | 0.97 |
| 880_V | 889_H | 1.343 | 0.97 |
| 734_L | 750_V | 1.342 | 0.97 |
| 694_I | 698_Q | 1.338 | 0.97 |
| 512_Q | 534_Q | 1.334 | 0.97 |
| 322_P | 325_G | 1.333 | 0.97 |
| 126_V | 156_V | 1.330 | 0.97 |
| 870_H | 873_N | 1.328 | 0.97 |
| 738_Y | 746_D | 1.327 | 0.97 |
| 847_I | 874_L | 1.326 | 0.97 |
| 866_T | 877_K | 1.326 | 0.97 |
| 590_E | 618_C | 1.320 | 0.97 |
| 46_T | 128_D | 1.316 | 0.97 |
| 697_A | 701_L | 1.316 | 0.97 |
| 546_T | 549_E | 1.314 | 0.97 |
| 188_H | 192_K | 1.313 | 0.97 |
| 847_I | 872_R | 1.311 | 0.97 |
| 196_D | 208_S | 1.304 | 0.96 |
| 708_E | 734_L | 1.303 | 0.96 |
| 873_N | 876_Q | 1.303 | 0.96 |
| 866_T | 870_H | 1.303 | 0.96 |
| 615_L | 619_S | 1.297 | 0.96 |
| 416_A | 432_L | 1.296 | 0.96 |
| 636_E | 656_R | 1.295 | 0.96 |
| 20_E | 190_E | 1.292 | 0.96 |
| 837_T | 877_K | 1.291 | 0.96 |
| 889_H | 893_L | 1.283 | 0.96 |
| 263_V | 267_T | 1.277 | 0.96 |
| 734_L | 738_Y | 1.275 | 0.96 |
| 20_E | 24_A | 1.275 | 0.96 |
| 731_L | 757_L | 1.271 | 0.96 |
| 473_K | 477_E | 1.269 | 0.96 |
| 280_M | 318_F | 1.265 | 0.96 |
| 865_T | 869_T | 1.262 | 0.95 |
| 749_R | 753_D | 1.262 | 0.95 |
| 53_A | 59_I | 1.258 | 0.95 |
| 556_Q | 560_E | 1.257 | 0.95 |
| 719_R | 727_L | 1.257 | 0.95 |
| 16_T | 19_R | 1.256 | 0.95 |
| 210_R | 214_D | 1.256 | 0.95 |
| 210_R | 213_D | 1.256 | 0.95 |
| 62_Y | 77_Y | 1.254 | 0.95 |
| 394_E | 398_K | 1.251 | 0.95 |
| 134_T | 138_I | 1.247 | 0.95 |
| 270_F | 294_G | 1.247 | 0.95 |
| 593_A | 615_L | 1.246 | 0.95 |
| 531_L | 557_L | 1.237 | 0.95 |
| 41_A | 323_L | 1.235 | 0.95 |
| 290_G | 346_A | 1.231 | 0.95 |
| 220_T | 321_H | 1.224 | 0.94 |
| 853_N | 883_R | 1.224 | 0.94 |
| 130_Y | 133_I | 1.221 | 0.94 |
| 531_L | 553_K | 1.217 | 0.94 |
| 551_Q | 575_I | 1.215 | 0.94 |
| 144_F | 148_H | 1.215 | 0.94 |
| 885_D | 888_Q | 1.211 | 0.94 |
| 746_D | 749_R | 1.205 | 0.94 |
| 851_Y | 855_Q | 1.204 | 0.94 |
| 270_F | 285_I | 1.204 | 0.94 |
| 192_K | 205_A | 1.202 | 0.94 |
| 661_Q | 697_A | 1.195 | 0.93 |
| 846_L | 859_E | 1.195 | 0.93 |
| 24_A | 28_G | 1.195 | 0.93 |
| 882_H | 885_D | 1.194 | 0.93 |
| 597_I | 615_L | 1.194 | 0.93 |
| 224_L | 227_L | 1.193 | 0.93 |
| 18_V | 23_L | 1.188 | 0.93 |
| 546_T | 550_T | 1.188 | 0.93 |
| 872_R | 876_Q | 1.187 | 0.93 |
| 123_L | 153_L | 1.186 | 0.93 |
| 880_V | 886_A | 1.184 | 0.93 |
| 552_E | 580_L | 1.182 | 0.93 |
| 21_R | 25_K | 1.181 | 0.93 |
| 670_A | 701_L | 1.180 | 0.93 |
| 671_N | 675_H | 1.180 | 0.93 |
| 195_F | 208_S | 1.179 | 0.93 |
| 847_I | 865_T | 1.176 | 0.93 |
| 511_M | 534_Q | 1.176 | 0.93 |
| 843_V | 860_L | 1.175 | 0.93 |
| 552_E | 556_Q | 1.175 | 0.93 |
| 47_T | 223_Q | 1.166 | 0.92 |
| 299_E | 303_R | 1.165 | 0.92 |
| 16_T | 51_Q | 1.163 | 0.92 |
| 550_T | 553_K | 1.162 | 0.92 |
| 666_K | 697_A | 1.157 | 0.92 |
| 853_N | 856_I | 1.157 | 0.92 |
| 512_Q | 543_F | 1.154 | 0.92 |
| 593_A | 611_C | 1.153 | 0.92 |
| 837_T | 873_N | 1.151 | 0.92 |
| 831_I | 835_P | 1.151 | 0.92 |
| 869_T | 872_R | 1.149 | 0.92 |
| 746_D | 750_V | 1.148 | 0.91 |
| 862_V | 870_H | 1.143 | 0.91 |
| 573_V | 599_V | 1.141 | 0.91 |
| 188_H | 213_D | 1.138 | 0.91 |
| 362_H | 366_A | 1.137 | 0.91 |
| 670_A | 697_A | 1.136 | 0.91 |
| 865_T | 868_K | 1.135 | 0.91 |
| 515_E | 534_Q | 1.135 | 0.91 |
| 753_D | 757_L | 1.133 | 0.91 |
| 580_L | 583_W | 1.132 | 0.91 |
| 45_K | 160_R | 1.130 | 0.91 |
| 695_A | 711_L | 1.129 | 0.91 |
| 358_S | 383_S | 1.126 | 0.90 |
| 41_A | 321_H | 1.126 | 0.90 |
| 559_N | 569_H | 1.126 | 0.90 |
| 695_A | 707_A | 1.125 | 0.90 |
| 712_E | 716_E | 1.124 | 0.90 |
| 308_L | 319_C | 1.120 | 0.90 |
| 365_L | 395_E | 1.115 | 0.90 |
| 555_F | 569_H | 1.114 | 0.90 |
| 573_V | 596_G | 1.113 | 0.90 |
| 850_G | 853_N | 1.110 | 0.90 |
| 47_T | 50_S | 1.108 | 0.89 |
| 37_I | 156_V | 1.107 | 0.89 |
| 57_N | 124_Y | 1.107 | 0.89 |
| 272_L | 332_C | 1.106 | 0.89 |
| 180_G | 183_Q | 1.106 | 0.89 |
| 633_N | 656_R | 1.106 | 0.89 |
| 656_R | 672_W | 1.105 | 0.89 |
| 216_S | 322_P | 1.105 | 0.89 |
| 279_S | 359_E | 1.102 | 0.89 |
| 727_L | 731_L | 1.101 | 0.89 |
| 160_R | 220_T | 1.101 | 0.89 |
| 188_H | 208_S | 1.101 | 0.89 |
| 750_V | 753_D | 1.095 | 0.89 |
| 257_D | 331_R | 1.094 | 0.89 |
| 506_R | 509_A | 1.094 | 0.89 |
| 711_L | 730_N | 1.093 | 0.89 |
| 866_T | 878_L | 1.093 | 0.89 |
| 364_A | 376_I | 1.091 | 0.88 |
| 274_S | 327_F | 1.089 | 0.88 |
| 257_D | 327_F | 1.085 | 0.88 |
| 62_Y | 127_I | 1.085 | 0.88 |
| 519_R | 553_K | 1.084 | 0.88 |
| 508_L | 538_L | 1.083 | 0.88 |
| 467_E | 470_R | 1.080 | 0.88 |
| 329_R | 344_H | 1.079 | 0.88 |
| 306_L | 324_F | 1.079 | 0.88 |
| 498_L | 510_L | 1.078 | 0.88 |
| 215_V | 222_L | 1.076 | 0.88 |
| 141_S | 145_F | 1.076 | 0.88 |
| 356_F | 359_E | 1.076 | 0.88 |
| 40_P | 185_A | 1.074 | 0.87 |
| 670_A | 694_I | 1.070 | 0.87 |
| 594_R | 598_E | 1.069 | 0.87 |
| 581_W | 586_L | 1.069 | 0.87 |
| 695_A | 714_L | 1.069 | 0.87 |
| 42_G | 45_K | 1.068 | 0.87 |
| 889_H | 892_Q | 1.066 | 0.87 |
| 342_E | 345_R | 1.066 | 0.87 |
| 548_W | 585_R | 1.065 | 0.87 |
| 857_A | 862_V | 1.064 | 0.87 |
| 38_T | 178_E | 1.063 | 0.87 |
| 198_R | 223_Q | 1.063 | 0.87 |
| 508_L | 534_Q | 1.062 | 0.87 |
| 340_L | 344_H | 1.058 | 0.86 |
| 53_A | 61_W | 1.057 | 0.86 |
| 875_Y | 882_H | 1.056 | 0.86 |
| 127_I | 157_V | 1.056 | 0.86 |
| 127_I | 142_M | 1.055 | 0.86 |
| 756_K | 759_N | 1.052 | 0.86 |
| 360_A | 364_A | 1.051 | 0.86 |
| 385_F | 418_L | 1.051 | 0.86 |
| 374_R | 378_L | 1.050 | 0.86 |
| 779_R | 782_I | 1.050 | 0.86 |
| 846_L | 851_Y | 1.050 | 0.86 |
| 19_R | 23_L | 1.047 | 0.86 |
| 220_T | 251_L | 1.047 | 0.86 |
| 267_T | 304_Q | 1.047 | 0.86 |
| 23_L | 51_Q | 1.045 | 0.85 |
| 322_P | 326_N | 1.045 | 0.85 |
| 509_A | 513_Q | 1.044 | 0.85 |
| 272_L | 331_R | 1.041 | 0.85 |
| 215_V | 225_I | 1.040 | 0.85 |
| 192_K | 196_D | 1.037 | 0.85 |
| 41_A | 254_Y | 1.037 | 0.85 |
| 266_A | 297_R | 1.036 | 0.85 |
| 833_T | 889_H | 1.036 | 0.85 |
| 222_L | 416_A | 1.036 | 0.85 |
| 629_R | 656_R | 1.035 | 0.85 |
| 360_A | 376_I | 1.035 | 0.85 |
| 796_Q | 799_L | 1.035 | 0.85 |
| 586_L | 618_C | 1.032 | 0.84 |
| 24_A | 27_S | 1.031 | 0.84 |
| 601_S | 634_R | 1.029 | 0.84 |
| 577_A | 614_M | 1.029 | 0.84 |
| 352_M | 376_I | 1.028 | 0.84 |
| 847_I | 886_A | 1.027 | 0.84 |
| 21_R | 187_T | 1.025 | 0.84 |
| 38_T | 159_S | 1.025 | 0.84 |
| 670_A | 674_R | 1.024 | 0.84 |
| 694_I | 710_V | 1.023 | 0.84 |
| 557_L | 560_E | 1.022 | 0.84 |
| 881_A | 884_Q | 1.021 | 0.84 |
| 752_L | 756_K | 1.020 | 0.83 |
| 128_D | 322_P | 1.020 | 0.83 |
| 412_V | 431_L | 1.018 | 0.83 |
| 33_R | 154_T | 1.018 | 0.83 |
| 661_Q | 669_A | 1.017 | 0.83 |
| 369_D | 372_M | 1.015 | 0.83 |
| 711_L | 715_N | 1.015 | 0.83 |
| 37_I | 179_I | 1.014 | 0.83 |
| 279_S | 317_W | 1.013 | 0.83 |
| 77_Y | 133_I | 1.012 | 0.83 |
| 549_E | 553_K | 1.012 | 0.83 |
| 850_G | 884_Q | 1.011 | 0.83 |
| 837_T | 870_H | 1.011 | 0.83 |
| 538_L | 550_T | 1.010 | 0.83 |
| 361_I | 380_H | 1.009 | 0.83 |
| 300_E | 304_Q | 1.009 | 0.83 |
| 270_F | 298_L | 1.008 | 0.82 |
| 272_L | 328_L | 1.008 | 0.82 |
| 276_I | 332_C | 1.007 | 0.82 |
| 473_K | 494_L | 1.007 | 0.82 |
| 339_E | 342_E | 1.004 | 0.82 |
| 512_Q | 516_Q | 1.002 | 0.82 |
| 281_N | 284_L | 1.002 | 0.82 |
| 709_I | 713_E | 1.002 | 0.82 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 1z6tA | 4 | 0.4761 | 100 | 0.72 | Contact Map |
| 2a5yB | 2 | 0.3818 | 100 | 0.763 | Contact Map |
| 1hz4A | 1 | 0.4062 | 100 | 0.775 | Contact Map |
| 2qenA | 1 | 0.3452 | 100 | 0.796 | Contact Map |
| 2fnaA | 2 | 0.3363 | 99.9 | 0.811 | Contact Map |
| 3sf4A | 3 | 0.3751 | 99.9 | 0.815 | Contact Map |
| 1w3bA | 2 | 0.4284 | 99.9 | 0.819 | Contact Map |
| 3ro2A | 1 | 0.343 | 99.9 | 0.823 | Contact Map |
| 4ui9O | 1 | 0 | 99.9 | 0.824 | Contact Map |
| 4a1sA | 2 | 0.3441 | 99.9 | 0.826 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)