| mexb |
| ID: | 1499799432 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 1000 (993) | ||
| Sequences: | 4580 (2704) | ||
| Seq/Len: | 4.612 | ||
| Nf(neff/√len): | 85.8 |
HHblits Results: (2016_02)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 4.612).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 957_G | 960_E | 4.942 | 1.00 |
| 309_T | 312_N | 4.638 | 1.00 |
| 244_E | 247_E | 4.627 | 1.00 |
| 591_V | 625_G | 4.201 | 1.00 |
| 304_K | 334_S | 4.149 | 1.00 |
| 169_T | 305_A | 4.091 | 1.00 |
| 247_E | 263_K | 4.043 | 1.00 |
| 62_V | 88_M | 3.992 | 1.00 |
| 142_V | 158_I | 3.802 | 1.00 |
| 154_L | 321_M | 3.570 | 1.00 |
| 47_V | 88_M | 3.503 | 1.00 |
| 65_I | 69_M | 3.388 | 1.00 |
| 311_A | 314_E | 3.363 | 1.00 |
| 165_P | 309_T | 3.360 | 1.00 |
| 76_R | 93_T | 3.326 | 1.00 |
| 735_A | 745_I | 3.309 | 1.00 |
| 193_L | 198_L | 3.274 | 1.00 |
| 680_F | 828_G | 3.216 | 1.00 |
| 248_N | 263_K | 3.201 | 1.00 |
| 75_L | 92_V | 3.155 | 1.00 |
| 729_E | 807_K | 3.138 | 1.00 |
| 58_Q | 822_P | 3.110 | 1.00 |
| 345_G | 349_L | 3.068 | 1.00 |
| 741_S | 744_D | 3.053 | 1.00 |
| 759_N | 770_V | 2.977 | 1.00 |
| 307_R | 328_D | 2.976 | 1.00 |
| 282_N | 608_S | 2.969 | 1.00 |
| 186_I | 207_I | 2.895 | 1.00 |
| 65_I | 90_I | 2.880 | 1.00 |
| 691_G | 694_V | 2.874 | 1.00 |
| 251_L | 265_V | 2.844 | 1.00 |
| 3_K | 7_D | 2.833 | 1.00 |
| 450_S | 479_A | 2.822 | 1.00 |
| 69_M | 90_I | 2.810 | 1.00 |
| 314_E | 322_K | 2.767 | 1.00 |
| 247_E | 268_V | 2.680 | 1.00 |
| 209_A | 736_S | 2.601 | 1.00 |
| 193_L | 265_V | 2.600 | 1.00 |
| 948_A | 962_A | 2.578 | 1.00 |
| 61_V | 122_V | 2.554 | 1.00 |
| 62_V | 82_S | 2.532 | 1.00 |
| 598_L | 651_A | 2.502 | 1.00 |
| 633_P | 636_E | 2.502 | 1.00 |
| 730_I | 735_A | 2.424 | 1.00 |
| 731_D | 805_T | 2.418 | 1.00 |
| 10_I | 888_A | 2.412 | 1.00 |
| 188_L | 203_V | 2.410 | 1.00 |
| 301_D | 305_A | 2.409 | 1.00 |
| 182_Y | 270_L | 2.376 | 1.00 |
| 262_L | 268_V | 2.376 | 1.00 |
| 14_V | 885_L | 2.356 | 1.00 |
| 189_D | 192_K | 2.331 | 1.00 |
| 588_Q | 592_D | 2.315 | 1.00 |
| 731_D | 734_K | 2.276 | 1.00 |
| 388_F | 472_I | 2.250 | 1.00 |
| 342_K | 346_E | 2.224 | 1.00 |
| 280_Q | 588_Q | 2.217 | 1.00 |
| 243_A | 247_E | 2.197 | 1.00 |
| 371_A | 484_V | 2.187 | 1.00 |
| 382_V | 476_S | 2.167 | 1.00 |
| 188_L | 200_P | 2.166 | 1.00 |
| 34_Q | 569_Q | 2.159 | 1.00 |
| 415_N | 418_R | 2.148 | 1.00 |
| 578_T | 582_S | 2.145 | 1.00 |
| 267_D | 775_R | 2.129 | 1.00 |
| 696_L | 700_N | 2.116 | 1.00 |
| 408_D | 939_K | 2.096 | 1.00 |
| 183_S | 771_Y | 2.086 | 1.00 |
| 45_V | 69_M | 2.085 | 1.00 |
| 280_Q | 595_R | 2.084 | 1.00 |
| 786_S | 801_N | 2.083 | 1.00 |
| 712_L | 715_V | 2.082 | 1.00 |
| 76_R | 95_E | 2.072 | 1.00 |
| 977_S | 981_I | 2.057 | 1.00 |
| 605_S | 642_N | 2.043 | 1.00 |
| 586_R | 589_V | 2.038 | 1.00 |
| 561_T | 837_G | 2.037 | 1.00 |
| 783_D | 786_S | 2.036 | 1.00 |
| 3_K | 432_R | 2.031 | 1.00 |
| 55_E | 59_D | 2.029 | 1.00 |
| 694_V | 697_Q | 2.020 | 1.00 |
| 730_I | 745_I | 2.020 | 1.00 |
| 684_L | 702_F | 2.017 | 1.00 |
| 4_F | 11_F | 2.003 | 1.00 |
| 338_H | 342_K | 1.999 | 1.00 |
| 429_E | 433_K | 1.983 | 1.00 |
| 62_V | 80_S | 1.983 | 1.00 |
| 781_N | 784_D | 1.978 | 1.00 |
| 740_V | 790_V | 1.974 | 1.00 |
| 45_V | 65_I | 1.972 | 1.00 |
| 606_V | 629_I | 1.958 | 1.00 |
| 339_E | 998_Q | 1.958 | 1.00 |
| 77_Y | 819_N | 1.957 | 1.00 |
| 699_R | 717_P | 1.953 | 1.00 |
| 587_T | 625_G | 1.951 | 1.00 |
| 740_V | 803_F | 1.914 | 1.00 |
| 698_A | 854_V | 1.905 | 1.00 |
| 82_S | 88_M | 1.899 | 1.00 |
| 378_G | 480_L | 1.899 | 1.00 |
| 572_L | 651_A | 1.895 | 1.00 |
| 69_M | 92_V | 1.879 | 1.00 |
| 613_T | 625_G | 1.875 | 1.00 |
| 642_N | 650_R | 1.868 | 1.00 |
| 57_V | 61_V | 1.859 | 1.00 |
| 74_N | 98_T | 1.849 | 1.00 |
| 20_M | 377_L | 1.843 | 1.00 |
| 650_R | 654_H | 1.840 | 1.00 |
| 199_T | 791_R | 1.820 | 1.00 |
| 205_S | 208_Q | 1.813 | 1.00 |
| 115_T | 124_R | 1.813 | 1.00 |
| 735_A | 740_V | 1.804 | 1.00 |
| 204_S | 772_L | 1.789 | 1.00 |
| 242_T | 245_Q | 1.788 | 1.00 |
| 120_Q | 124_R | 1.787 | 1.00 |
| 78_I | 92_V | 1.785 | 1.00 |
| 426_S | 429_E | 1.785 | 1.00 |
| 951_L | 956_K | 1.774 | 1.00 |
| 729_E | 805_T | 1.768 | 1.00 |
| 728_L | 804_A | 1.765 | 1.00 |
| 8_R | 892_E | 1.762 | 1.00 |
| 65_I | 114_A | 1.754 | 1.00 |
| 43_I | 104_Q | 1.753 | 1.00 |
| 591_V | 613_T | 1.746 | 1.00 |
| 145_T | 322_K | 1.743 | 1.00 |
| 697_Q | 701_K | 1.743 | 1.00 |
| 597_Y | 654_H | 1.733 | 1.00 |
| 190_P | 778_A | 1.733 | 1.00 |
| 592_D | 595_R | 1.730 | 0.99 |
| 844_E | 866_R | 1.726 | 0.99 |
| 202_D | 791_R | 1.725 | 0.99 |
| 956_K | 964_E | 1.721 | 0.99 |
| 479_A | 483_I | 1.718 | 0.99 |
| 181_Q | 273_Q | 1.714 | 0.99 |
| 594_M | 655_F | 1.714 | 0.99 |
| 985_V | 989_I | 1.711 | 0.99 |
| 189_D | 267_D | 1.709 | 0.99 |
| 593_S | 597_Y | 1.707 | 0.99 |
| 47_V | 62_V | 1.705 | 0.99 |
| 903_V | 941_A | 1.705 | 0.99 |
| 339_E | 342_K | 1.687 | 0.99 |
| 7_D | 428_R | 1.687 | 0.99 |
| 75_L | 78_I | 1.686 | 0.99 |
| 562_A | 923_D | 1.686 | 0.99 |
| 68_Q | 114_A | 1.683 | 0.99 |
| 241_Q | 245_Q | 1.665 | 0.99 |
| 706_A | 843_V | 1.665 | 0.99 |
| 297_A | 302_T | 1.661 | 0.99 |
| 305_A | 308_Q | 1.649 | 0.99 |
| 379_T | 477_A | 1.636 | 0.99 |
| 574_A | 629_I | 1.633 | 0.99 |
| 835_S | 838_D | 1.632 | 0.99 |
| 203_V | 265_V | 1.624 | 0.99 |
| 419_V | 437_Q | 1.613 | 0.99 |
| 974_V | 978_L | 1.607 | 0.99 |
| 19_I | 378_G | 1.606 | 0.99 |
| 445_I | 482_V | 1.605 | 0.99 |
| 193_L | 196_Y | 1.601 | 0.99 |
| 607_S | 632_K | 1.599 | 0.99 |
| 24_G | 28_L | 1.594 | 0.99 |
| 775_R | 778_A | 1.593 | 0.99 |
| 207_I | 249_I | 1.584 | 0.99 |
| 609_V | 627_A | 1.581 | 0.99 |
| 745_I | 803_F | 1.577 | 0.99 |
| 591_V | 611_T | 1.572 | 0.99 |
| 188_L | 193_L | 1.567 | 0.99 |
| 245_Q | 248_N | 1.564 | 0.99 |
| 53_S | 56_T | 1.562 | 0.99 |
| 951_L | 964_E | 1.548 | 0.99 |
| 472_I | 476_S | 1.541 | 0.99 |
| 533_S | 537_H | 1.540 | 0.99 |
| 244_E | 248_N | 1.540 | 0.99 |
| 262_L | 266_A | 1.538 | 0.99 |
| 537_H | 540_P | 1.534 | 0.99 |
| 13_W | 894_W | 1.529 | 0.98 |
| 593_S | 596_E | 1.527 | 0.98 |
| 703_L | 715_V | 1.526 | 0.98 |
| 423_E | 433_K | 1.516 | 0.98 |
| 714_R | 829_E | 1.513 | 0.98 |
| 884_F | 888_A | 1.512 | 0.98 |
| 572_L | 648_A | 1.511 | 0.98 |
| 170_K | 305_A | 1.506 | 0.98 |
| 172_V | 291_I | 1.505 | 0.98 |
| 703_L | 707_A | 1.501 | 0.98 |
| 305_A | 309_T | 1.500 | 0.98 |
| 11_F | 889_A | 1.499 | 0.98 |
| 169_T | 309_T | 1.499 | 0.98 |
| 632_K | 636_E | 1.491 | 0.98 |
| 175_F | 289_I | 1.486 | 0.98 |
| 187_W | 269_G | 1.485 | 0.98 |
| 605_S | 632_K | 1.484 | 0.98 |
| 112_Q | 115_T | 1.483 | 0.98 |
| 196_Y | 260_V | 1.482 | 0.98 |
| 142_V | 323_V | 1.482 | 0.98 |
| 185_R | 773_Q | 1.480 | 0.98 |
| 643_S | 646_E | 1.479 | 0.98 |
| 307_R | 325_Y | 1.478 | 0.98 |
| 14_V | 889_A | 1.477 | 0.98 |
| 896_I | 949_K | 1.472 | 0.98 |
| 582_S | 586_R | 1.464 | 0.98 |
| 528_E | 967_R | 1.456 | 0.98 |
| 418_R | 968_M | 1.454 | 0.98 |
| 218_Q | 231_N | 1.454 | 0.98 |
| 13_W | 17_L | 1.452 | 0.98 |
| 301_D | 304_K | 1.451 | 0.98 |
| 92_V | 107_V | 1.450 | 0.98 |
| 328_D | 331_P | 1.448 | 0.98 |
| 156_N | 160_S | 1.447 | 0.98 |
| 576_V | 625_G | 1.443 | 0.98 |
| 686_D | 854_V | 1.442 | 0.98 |
| 576_V | 594_M | 1.434 | 0.97 |
| 915_T | 926_F | 1.434 | 0.97 |
| 834_L | 838_D | 1.432 | 0.97 |
| 712_L | 839_A | 1.428 | 0.97 |
| 651_A | 655_F | 1.426 | 0.97 |
| 683_F | 823_A | 1.426 | 0.97 |
| 694_V | 698_A | 1.424 | 0.97 |
| 66_E | 817_R | 1.422 | 0.97 |
| 578_T | 587_T | 1.418 | 0.97 |
| 172_V | 302_T | 1.412 | 0.97 |
| 702_F | 847_V | 1.411 | 0.97 |
| 834_L | 842_A | 1.410 | 0.97 |
| 26_S | 384_A | 1.408 | 0.97 |
| 711_A | 834_L | 1.408 | 0.97 |
| 98_T | 106_Q | 1.404 | 0.97 |
| 699_R | 824_M | 1.403 | 0.97 |
| 370_I | 492_L | 1.401 | 0.97 |
| 199_T | 202_D | 1.400 | 0.97 |
| 441_A | 950_E | 1.400 | 0.97 |
| 57_V | 82_S | 1.399 | 0.97 |
| 62_V | 90_I | 1.397 | 0.97 |
| 473_T | 477_A | 1.395 | 0.97 |
| 7_D | 432_R | 1.394 | 0.97 |
| 142_V | 154_L | 1.394 | 0.97 |
| 592_D | 596_E | 1.388 | 0.97 |
| 334_S | 338_H | 1.386 | 0.97 |
| 163_Q | 167_S | 1.385 | 0.97 |
| 140_V | 325_Y | 1.385 | 0.97 |
| 606_V | 609_V | 1.384 | 0.97 |
| 45_V | 92_V | 1.382 | 0.97 |
| 99_D | 102_I | 1.375 | 0.96 |
| 598_L | 606_V | 1.373 | 0.96 |
| 198_L | 202_D | 1.372 | 0.96 |
| 22_A | 381_G | 1.371 | 0.96 |
| 204_S | 208_Q | 1.371 | 0.96 |
| 590_V | 593_S | 1.369 | 0.96 |
| 547_V | 551_G | 1.368 | 0.96 |
| 158_I | 162_I | 1.368 | 0.96 |
| 352_F | 369_T | 1.368 | 0.96 |
| 701_K | 705_L | 1.361 | 0.96 |
| 74_N | 95_E | 1.359 | 0.96 |
| 684_L | 699_R | 1.354 | 0.96 |
| 425_L | 433_K | 1.353 | 0.96 |
| 923_D | 926_F | 1.350 | 0.96 |
| 542_L | 546_V | 1.349 | 0.96 |
| 202_D | 205_S | 1.346 | 0.96 |
| 594_M | 658_F | 1.343 | 0.96 |
| 310_I | 323_V | 1.340 | 0.96 |
| 791_R | 797_M | 1.338 | 0.96 |
| 711_A | 842_A | 1.338 | 0.96 |
| 143_V | 322_K | 1.335 | 0.96 |
| 593_S | 660_D | 1.335 | 0.96 |
| 231_N | 276_S | 1.334 | 0.96 |
| 43_I | 107_V | 1.332 | 0.96 |
| 115_T | 123_Q | 1.332 | 0.96 |
| 142_V | 162_I | 1.331 | 0.96 |
| 595_R | 609_V | 1.330 | 0.95 |
| 47_V | 65_I | 1.329 | 0.95 |
| 684_L | 826_I | 1.324 | 0.95 |
| 698_A | 850_L | 1.317 | 0.95 |
| 240_L | 246_F | 1.316 | 0.95 |
| 254_N | 258_S | 1.314 | 0.95 |
| 549_V | 553_I | 1.313 | 0.95 |
| 162_I | 313_L | 1.308 | 0.95 |
| 148_S | 320_G | 1.306 | 0.95 |
| 137_L | 303_A | 1.302 | 0.95 |
| 273_Q | 769_R | 1.302 | 0.95 |
| 482_V | 979_A | 1.295 | 0.95 |
| 680_F | 843_V | 1.295 | 0.95 |
| 681_D | 825_E | 1.294 | 0.95 |
| 562_A | 921_S | 1.292 | 0.94 |
| 727_K | 809_E | 1.290 | 0.94 |
| 970_L | 974_V | 1.289 | 0.94 |
| 647_L | 650_R | 1.287 | 0.94 |
| 896_I | 899_S | 1.287 | 0.94 |
| 840_M | 862_S | 1.284 | 0.94 |
| 304_K | 308_Q | 1.283 | 0.94 |
| 982_L | 985_V | 1.282 | 0.94 |
| 727_K | 807_K | 1.280 | 0.94 |
| 433_K | 436_G | 1.275 | 0.94 |
| 642_N | 647_L | 1.274 | 0.94 |
| 47_V | 122_V | 1.274 | 0.94 |
| 446_A | 482_V | 1.271 | 0.94 |
| 141_G | 281_F | 1.271 | 0.94 |
| 46_Q | 89_T | 1.266 | 0.94 |
| 576_V | 591_V | 1.260 | 0.93 |
| 412_V | 435_M | 1.259 | 0.93 |
| 26_S | 381_G | 1.259 | 0.93 |
| 29_S | 384_A | 1.258 | 0.93 |
| 734_K | 737_A | 1.251 | 0.93 |
| 841_A | 844_E | 1.250 | 0.93 |
| 705_L | 846_I | 1.248 | 0.93 |
| 158_I | 289_I | 1.245 | 0.93 |
| 317_M | 323_V | 1.243 | 0.93 |
| 157_Y | 321_M | 1.241 | 0.93 |
| 740_V | 745_I | 1.239 | 0.93 |
| 698_A | 701_K | 1.236 | 0.93 |
| 699_R | 703_L | 1.234 | 0.93 |
| 68_Q | 113_L | 1.233 | 0.92 |
| 166_L | 175_F | 1.232 | 0.92 |
| 349_L | 353_L | 1.230 | 0.92 |
| 239_R | 762_I | 1.228 | 0.92 |
| 280_Q | 592_D | 1.227 | 0.92 |
| 790_V | 803_F | 1.227 | 0.92 |
| 303_A | 330_T | 1.226 | 0.92 |
| 102_I | 105_V | 1.224 | 0.92 |
| 712_L | 828_G | 1.221 | 0.92 |
| 309_T | 313_L | 1.220 | 0.92 |
| 522_S | 526_G | 1.220 | 0.92 |
| 58_Q | 815_L | 1.219 | 0.92 |
| 528_E | 532_A | 1.217 | 0.92 |
| 415_N | 437_Q | 1.216 | 0.92 |
| 959_V | 963_I | 1.215 | 0.92 |
| 799_P | 802_A | 1.214 | 0.92 |
| 702_F | 826_I | 1.208 | 0.91 |
| 77_Y | 93_T | 1.203 | 0.91 |
| 383_L | 388_F | 1.203 | 0.91 |
| 207_I | 758_V | 1.203 | 0.91 |
| 449_L | 939_K | 1.202 | 0.91 |
| 361_N | 417_E | 1.200 | 0.91 |
| 685_Q | 857_S | 1.195 | 0.91 |
| 145_T | 148_S | 1.193 | 0.91 |
| 65_I | 111_L | 1.187 | 0.90 |
| 79_S | 93_T | 1.186 | 0.90 |
| 725_Q | 811_G | 1.185 | 0.90 |
| 218_Q | 276_S | 1.184 | 0.90 |
| 379_T | 476_S | 1.184 | 0.90 |
| 572_L | 629_I | 1.183 | 0.90 |
| 98_T | 103_A | 1.181 | 0.90 |
| 408_D | 979_A | 1.181 | 0.90 |
| 50_P | 123_Q | 1.181 | 0.90 |
| 307_R | 330_T | 1.180 | 0.90 |
| 818_Y | 859_T | 1.178 | 0.90 |
| 42_A | 91_T | 1.178 | 0.90 |
| 94_F | 107_V | 1.177 | 0.90 |
| 744_D | 747_S | 1.173 | 0.90 |
| 234_I | 753_W | 1.173 | 0.90 |
| 95_E | 98_T | 1.171 | 0.90 |
| 785_L | 806_G | 1.169 | 0.90 |
| 842_A | 846_I | 1.164 | 0.89 |
| 416_V | 493_C | 1.162 | 0.89 |
| 728_L | 806_G | 1.161 | 0.89 |
| 140_V | 289_I | 1.159 | 0.89 |
| 27_I | 390_I | 1.159 | 0.89 |
| 163_Q | 177_V | 1.156 | 0.89 |
| 839_A | 842_A | 1.156 | 0.89 |
| 838_D | 841_A | 1.156 | 0.89 |
| 1_M | 5_F | 1.155 | 0.89 |
| 842_A | 845_E | 1.152 | 0.89 |
| 382_V | 386_F | 1.152 | 0.89 |
| 529_R | 533_S | 1.150 | 0.89 |
| 792_N | 796_E | 1.149 | 0.89 |
| 193_L | 203_V | 1.148 | 0.88 |
| 573_F | 628_F | 1.143 | 0.88 |
| 216_S | 749_V | 1.143 | 0.88 |
| 602_E | 605_S | 1.142 | 0.88 |
| 550_A | 553_I | 1.141 | 0.88 |
| 784_D | 787_K | 1.141 | 0.88 |
| 184_M | 761_F | 1.139 | 0.88 |
| 885_L | 889_A | 1.137 | 0.88 |
| 439_Q | 443_V | 1.136 | 0.88 |
| 200_P | 751_I | 1.135 | 0.88 |
| 574_A | 598_L | 1.135 | 0.88 |
| 921_S | 926_F | 1.134 | 0.88 |
| 522_S | 525_H | 1.134 | 0.88 |
| 157_Y | 161_N | 1.134 | 0.88 |
| 700_N | 703_L | 1.130 | 0.87 |
| 304_K | 307_R | 1.130 | 0.87 |
| 58_Q | 817_R | 1.128 | 0.87 |
| 404_L | 980_F | 1.127 | 0.87 |
| 449_L | 478_M | 1.126 | 0.87 |
| 139_V | 290_A | 1.123 | 0.87 |
| 701_K | 704_M | 1.122 | 0.87 |
| 543_L | 550_A | 1.121 | 0.87 |
| 684_L | 854_V | 1.121 | 0.87 |
| 5_F | 12_A | 1.120 | 0.87 |
| 81_E | 91_T | 1.120 | 0.87 |
| 903_V | 906_L | 1.118 | 0.87 |
| 590_V | 658_F | 1.116 | 0.86 |
| 815_L | 822_P | 1.114 | 0.86 |
| 649_K | 652_Q | 1.113 | 0.86 |
| 703_L | 826_I | 1.113 | 0.86 |
| 428_R | 432_R | 1.113 | 0.86 |
| 31_P | 389_S | 1.110 | 0.86 |
| 595_R | 611_T | 1.110 | 0.86 |
| 192_K | 196_Y | 1.109 | 0.86 |
| 518_R | 522_S | 1.109 | 0.86 |
| 593_S | 658_F | 1.107 | 0.86 |
| 69_M | 75_L | 1.107 | 0.86 |
| 956_K | 960_E | 1.106 | 0.86 |
| 155_S | 180_S | 1.103 | 0.86 |
| 169_T | 302_T | 1.102 | 0.86 |
| 206_A | 249_I | 1.102 | 0.86 |
| 47_V | 82_S | 1.102 | 0.86 |
| 2_S | 435_M | 1.100 | 0.85 |
| 278_N | 588_Q | 1.099 | 0.85 |
| 445_I | 979_A | 1.097 | 0.85 |
| 386_F | 476_S | 1.097 | 0.85 |
| 278_N | 613_T | 1.097 | 0.85 |
| 920_L | 999_H | 1.096 | 0.85 |
| 383_L | 472_I | 1.094 | 0.85 |
| 432_R | 436_G | 1.094 | 0.85 |
| 465_V | 468_R | 1.092 | 0.85 |
| 911_A | 930_L | 1.091 | 0.85 |
| 706_A | 712_L | 1.087 | 0.84 |
| 834_L | 839_A | 1.087 | 0.84 |
| 146_D | 320_G | 1.087 | 0.84 |
| 958_I | 962_A | 1.086 | 0.84 |
| 922_N | 926_F | 1.084 | 0.84 |
| 313_L | 317_M | 1.084 | 0.84 |
| 683_F | 818_Y | 1.083 | 0.84 |
| 734_K | 738_L | 1.083 | 0.84 |
| 442_L | 482_V | 1.081 | 0.84 |
| 703_L | 717_P | 1.080 | 0.84 |
| 150_T | 153_D | 1.079 | 0.84 |
| 47_V | 125_Q | 1.078 | 0.84 |
| 693_E | 696_L | 1.076 | 0.84 |
| 110_K | 113_L | 1.076 | 0.84 |
| 6_I | 432_R | 1.075 | 0.84 |
| 898_F | 902_L | 1.072 | 0.83 |
| 758_V | 772_L | 1.072 | 0.83 |
| 145_T | 320_G | 1.072 | 0.83 |
| 347_A | 351_V | 1.071 | 0.83 |
| 415_N | 419_V | 1.071 | 0.83 |
| 578_T | 590_V | 1.071 | 0.83 |
| 203_V | 772_L | 1.068 | 0.83 |
| 462_S | 563_F | 1.068 | 0.83 |
| 163_Q | 175_F | 1.065 | 0.83 |
| 367_I | 492_L | 1.065 | 0.83 |
| 591_V | 627_A | 1.065 | 0.83 |
| 873_P | 877_A | 1.065 | 0.83 |
| 70_N | 820_G | 1.064 | 0.83 |
| 279_A | 288_G | 1.063 | 0.83 |
| 246_F | 262_L | 1.059 | 0.82 |
| 745_I | 800_F | 1.059 | 0.82 |
| 419_V | 433_K | 1.057 | 0.82 |
| 16_A | 19_I | 1.056 | 0.82 |
| 48_S | 87_S | 1.056 | 0.82 |
| 602_E | 647_L | 1.055 | 0.82 |
| 211_N | 759_N | 1.054 | 0.82 |
| 700_N | 704_M | 1.053 | 0.82 |
| 192_K | 734_K | 1.052 | 0.82 |
| 388_F | 475_V | 1.051 | 0.82 |
| 388_F | 469_Q | 1.051 | 0.82 |
| 530_G | 533_S | 1.050 | 0.82 |
| 41_P | 94_F | 1.049 | 0.82 |
| 602_E | 654_H | 1.048 | 0.81 |
| 719_G | 824_M | 1.048 | 0.81 |
| 382_V | 480_L | 1.048 | 0.81 |
| 288_G | 610_F | 1.047 | 0.81 |
| 76_R | 863_Y | 1.044 | 0.81 |
| 144_S | 320_G | 1.044 | 0.81 |
| 977_S | 980_F | 1.043 | 0.81 |
| 597_Y | 651_A | 1.042 | 0.81 |
| 702_F | 846_I | 1.040 | 0.81 |
| 709_N | 842_A | 1.040 | 0.81 |
| 201_G | 744_D | 1.038 | 0.81 |
| 178_F | 290_A | 1.036 | 0.80 |
| 30_L | 390_I | 1.036 | 0.80 |
| 447_M | 886_C | 1.035 | 0.80 |
| 205_S | 209_A | 1.033 | 0.80 |
| 201_G | 205_S | 1.031 | 0.80 |
| 69_M | 78_I | 1.030 | 0.80 |
| 69_M | 107_V | 1.029 | 0.80 |
| 352_F | 372_V | 1.029 | 0.80 |
| 417_E | 421_A | 1.028 | 0.80 |
| 291_I | 306_I | 1.028 | 0.80 |
| 879_S | 931_L | 1.028 | 0.80 |
| 914_A | 918_R | 1.027 | 0.80 |
| 250_L | 259_Q | 1.027 | 0.80 |
| 841_A | 845_E | 1.026 | 0.79 |
| 551_G | 555_M | 1.026 | 0.79 |
| 940_N | 977_S | 1.023 | 0.79 |
| 830_P | 839_A | 1.023 | 0.79 |
| 214_I | 746_N | 1.022 | 0.79 |
| 404_L | 979_A | 1.022 | 0.79 |
| 594_M | 627_A | 1.020 | 0.79 |
| 281_F | 286_A | 1.015 | 0.78 |
| 558_R | 916_S | 1.015 | 0.78 |
| 876_Y | 934_I | 1.014 | 0.78 |
| 30_L | 380_F | 1.013 | 0.78 |
| 145_T | 284_S | 1.013 | 0.78 |
| 335_A | 338_H | 1.011 | 0.78 |
| 526_G | 530_G | 1.009 | 0.78 |
| 366_L | 496_M | 1.008 | 0.78 |
| 978_L | 982_L | 1.007 | 0.78 |
| 2_S | 6_I | 1.006 | 0.78 |
| 492_L | 496_M | 1.006 | 0.78 |
| 413_V | 434_S | 1.005 | 0.78 |
| 166_L | 309_T | 1.005 | 0.78 |
| 3_K | 436_G | 1.005 | 0.78 |
| 198_L | 251_L | 1.004 | 0.77 |
| 952_H | 958_I | 1.004 | 0.77 |
| 360_Q | 517_N | 1.003 | 0.77 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 4k0jA | 6 | 0.93 | 100 | 0.282 | Contact Map |
| 4mt1A | 1 | 0.974 | 100 | 0.343 | Contact Map |
| 3ne5A | 1 | 0.961 | 100 | 0.353 | Contact Map |
| 3w9iA | 6 | 0.995 | 100 | 0.353 | Contact Map |
| 4dx5A | 3 | 0.996 | 100 | 0.366 | Contact Map |
| 4r86A | 2 | 0.289 | 100 | 0.76 | Contact Map |
| 3aqpA | 2 | 0.665 | 100 | 0.779 | Contact Map |
| 2ew9A | 1 | 0.149 | 76 | 0.984 | Contact Map |
| 4n8nA | 4 | 0.1 | 70.7 | 0.985 | Contact Map |
| 4q2lA | 1 | 0.06 | 61.2 | 0.986 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)