| cxcr4_C-HIV |
| ID: | 1497836859 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 856 (852) | ||
| Sequences: | 2764 (345.8) | ||
| Seq/Len: | 3.244 | ||
| Nf(neff/√len): | 11.8 |
HHblits Results: (2016_02)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 3.244).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 283_T | 453_L | 4.858 | 1.00 |
| 502_K | 607_A | 3.866 | 1.00 |
| 632_D | 636_N | 3.531 | 1.00 |
| 755_L | 758_D | 3.162 | 1.00 |
| 747_R | 758_D | 3.144 | 1.00 |
| 293_E | 337_K | 3.052 | 1.00 |
| 348_K | 351_E | 2.910 | 1.00 |
| 659_E | 662_E | 2.873 | 1.00 |
| 275_V | 278_T | 2.861 | 1.00 |
| 658_Q | 662_E | 2.853 | 1.00 |
| 330_H | 334_S | 2.634 | 1.00 |
| 620_E | 624_N | 2.609 | 1.00 |
| 211_E | 379_G | 2.400 | 1.00 |
| 325_N | 419_R | 2.364 | 1.00 |
| 825_G | 829_V | 2.301 | 1.00 |
| 62_D | 65_V | 2.282 | 1.00 |
| 824_E | 829_V | 2.264 | 1.00 |
| 65_V | 208_V | 2.223 | 1.00 |
| 114_Q | 202_T | 2.206 | 1.00 |
| 655_K | 658_Q | 2.198 | 1.00 |
| 97_K | 275_V | 2.194 | 1.00 |
| 159_F | 174_A | 2.165 | 1.00 |
| 671_N | 683_K | 2.139 | 1.00 |
| 332_N | 336_A | 2.139 | 1.00 |
| 92_N | 238_P | 2.099 | 1.00 |
| 662_E | 665_K | 2.088 | 1.00 |
| 230_N | 240_T | 2.080 | 1.00 |
| 630_E | 633_R | 2.062 | 1.00 |
| 231_K | 267_E | 2.061 | 1.00 |
| 270_V | 277_F | 2.032 | 1.00 |
| 275_V | 279_D | 2.024 | 1.00 |
| 817_A | 821_A | 2.019 | 1.00 |
| 360_I | 465_S | 2.005 | 1.00 |
| 219_A | 225_I | 2.000 | 1.00 |
| 641_L | 644_S | 1.973 | 1.00 |
| 308_R | 316_A | 1.964 | 1.00 |
| 801_Q | 825_G | 1.955 | 1.00 |
| 161_I | 172_E | 1.952 | 1.00 |
| 279_D | 474_D | 1.928 | 1.00 |
| 746_I | 758_D | 1.916 | 1.00 |
| 85_V | 229_N | 1.915 | 1.00 |
| 195_S | 200_V | 1.891 | 0.99 |
| 198_T | 202_T | 1.870 | 0.99 |
| 429_K | 432_K | 1.870 | 0.99 |
| 21_L | 25_L | 1.853 | 0.99 |
| 797_W | 800_L | 1.829 | 0.99 |
| 805_Q | 809_N | 1.806 | 0.99 |
| 305_K | 319_T | 1.800 | 0.99 |
| 813_S | 817_A | 1.768 | 0.99 |
| 46_K | 636_N | 1.759 | 0.99 |
| 21_L | 24_M | 1.759 | 0.99 |
| 421_K | 424_I | 1.743 | 0.99 |
| 775_L | 796_W | 1.694 | 0.99 |
| 346_A | 393_S | 1.692 | 0.99 |
| 852_E | 855_L | 1.691 | 0.99 |
| 732_G | 788_R | 1.689 | 0.99 |
| 788_R | 792_A | 1.688 | 0.99 |
| 849_Q | 852_E | 1.685 | 0.99 |
| 801_Q | 824_E | 1.679 | 0.98 |
| 721_L | 756_I | 1.676 | 0.98 |
| 798_N | 801_Q | 1.676 | 0.98 |
| 651_N | 658_Q | 1.674 | 0.98 |
| 815_L | 818_T | 1.655 | 0.98 |
| 27_I | 614_W | 1.640 | 0.98 |
| 167_G | 192_K | 1.634 | 0.98 |
| 232_T | 268_E | 1.628 | 0.98 |
| 328_Q | 334_S | 1.627 | 0.98 |
| 833_V | 837_C | 1.624 | 0.98 |
| 49_T | 99_D | 1.619 | 0.98 |
| 289_N | 344_Q | 1.596 | 0.98 |
| 17_W | 20_M | 1.588 | 0.98 |
| 567_Q | 629_M | 1.580 | 0.97 |
| 26_M | 614_W | 1.578 | 0.97 |
| 211_E | 223_F | 1.575 | 0.97 |
| 223_F | 287_Q | 1.574 | 0.97 |
| 360_I | 467_I | 1.570 | 0.97 |
| 65_V | 68_V | 1.567 | 0.97 |
| 564_H | 567_Q | 1.559 | 0.97 |
| 20_M | 24_M | 1.555 | 0.97 |
| 270_V | 346_A | 1.549 | 0.97 |
| 750_N | 756_I | 1.549 | 0.97 |
| 359_I | 614_W | 1.548 | 0.97 |
| 26_M | 615_S | 1.547 | 0.97 |
| 845_R | 851_L | 1.545 | 0.97 |
| 106_E | 174_A | 1.542 | 0.97 |
| 269_E | 348_K | 1.537 | 0.97 |
| 700_A | 758_D | 1.531 | 0.97 |
| 722_P | 726_G | 1.531 | 0.97 |
| 837_C | 840_I | 1.521 | 0.97 |
| 471_G | 474_D | 1.514 | 0.97 |
| 844_P | 849_Q | 1.500 | 0.96 |
| 816_N | 825_G | 1.500 | 0.96 |
| 46_K | 49_T | 1.499 | 0.96 |
| 232_T | 240_T | 1.499 | 0.96 |
| 758_D | 764_C | 1.481 | 0.96 |
| 747_R | 755_L | 1.468 | 0.96 |
| 10_L | 25_L | 1.458 | 0.95 |
| 665_K | 677_N | 1.457 | 0.95 |
| 359_I | 615_S | 1.453 | 0.95 |
| 522_F | 713_S | 1.452 | 0.95 |
| 7_Y | 21_L | 1.450 | 0.95 |
| 805_Q | 853_R | 1.446 | 0.95 |
| 290_T | 340_N | 1.440 | 0.95 |
| 837_C | 841_R | 1.437 | 0.95 |
| 236_T | 275_V | 1.434 | 0.95 |
| 783_E | 786_G | 1.431 | 0.95 |
| 756_I | 775_L | 1.429 | 0.95 |
| 844_P | 848_R | 1.427 | 0.95 |
| 774_L | 781_I | 1.425 | 0.95 |
| 92_N | 633_R | 1.421 | 0.95 |
| 849_Q | 855_L | 1.416 | 0.94 |
| 565_L | 646_I | 1.416 | 0.94 |
| 295_N | 446_S | 1.414 | 0.94 |
| 676_T | 683_K | 1.412 | 0.94 |
| 615_S | 799_L | 1.411 | 0.94 |
| 13_W | 21_L | 1.411 | 0.94 |
| 740_R | 746_I | 1.407 | 0.94 |
| 825_G | 833_V | 1.406 | 0.94 |
| 846_R | 849_Q | 1.398 | 0.94 |
| 47_E | 629_M | 1.397 | 0.94 |
| 232_T | 236_T | 1.395 | 0.94 |
| 21_L | 796_W | 1.394 | 0.94 |
| 92_N | 630_E | 1.388 | 0.94 |
| 335_R | 412_D | 1.386 | 0.94 |
| 614_W | 799_L | 1.386 | 0.94 |
| 770_R | 773_D | 1.382 | 0.93 |
| 27_I | 615_S | 1.378 | 0.93 |
| 784_L | 787_R | 1.377 | 0.93 |
| 231_K | 268_E | 1.376 | 0.93 |
| 49_T | 632_D | 1.360 | 0.93 |
| 816_N | 824_E | 1.358 | 0.93 |
| 308_R | 315_R | 1.355 | 0.93 |
| 178_K | 195_S | 1.355 | 0.93 |
| 150_E | 154_I | 1.354 | 0.92 |
| 1_M | 5_E | 1.354 | 0.92 |
| 721_L | 750_N | 1.353 | 0.92 |
| 164_S | 195_S | 1.351 | 0.92 |
| 333_I | 341_T | 1.350 | 0.92 |
| 646_I | 698_V | 1.349 | 0.92 |
| 22_L | 29_S | 1.343 | 0.92 |
| 848_R | 852_E | 1.342 | 0.92 |
| 518_L | 553_N | 1.341 | 0.92 |
| 740_R | 756_I | 1.339 | 0.92 |
| 369_P | 373_T | 1.339 | 0.92 |
| 797_W | 804_S | 1.338 | 0.92 |
| 745_S | 748_L | 1.337 | 0.92 |
| 797_W | 809_N | 1.335 | 0.92 |
| 723_T | 756_I | 1.326 | 0.91 |
| 85_V | 629_M | 1.325 | 0.91 |
| 10_L | 24_M | 1.324 | 0.91 |
| 1_M | 614_W | 1.323 | 0.91 |
| 740_R | 796_W | 1.317 | 0.91 |
| 842_H | 853_R | 1.315 | 0.91 |
| 174_A | 567_Q | 1.315 | 0.91 |
| 223_F | 490_K | 1.314 | 0.91 |
| 202_T | 425_N | 1.312 | 0.91 |
| 792_A | 801_Q | 1.311 | 0.91 |
| 65_V | 287_Q | 1.311 | 0.91 |
| 372_V | 507_Q | 1.310 | 0.91 |
| 698_V | 705_V | 1.309 | 0.91 |
| 328_Q | 332_N | 1.305 | 0.91 |
| 62_D | 209_S | 1.303 | 0.90 |
| 425_N | 432_K | 1.303 | 0.90 |
| 667_A | 674_N | 1.300 | 0.90 |
| 440_S | 444_R | 1.296 | 0.90 |
| 553_N | 651_N | 1.296 | 0.90 |
| 850_G | 855_L | 1.293 | 0.90 |
| 721_L | 732_G | 1.291 | 0.90 |
| 305_K | 321_G | 1.289 | 0.90 |
| 722_P | 825_G | 1.288 | 0.90 |
| 2_R | 621_Q | 1.286 | 0.90 |
| 836_A | 839_A | 1.286 | 0.90 |
| 788_R | 801_Q | 1.285 | 0.90 |
| 21_L | 49_T | 1.282 | 0.89 |
| 722_P | 824_E | 1.282 | 0.89 |
| 8_Q | 796_W | 1.279 | 0.89 |
| 133_D | 137_D | 1.275 | 0.89 |
| 747_R | 754_A | 1.275 | 0.89 |
| 132_T | 698_V | 1.274 | 0.89 |
| 444_R | 492_E | 1.273 | 0.89 |
| 330_H | 415_T | 1.271 | 0.89 |
| 442_Q | 446_S | 1.270 | 0.89 |
| 10_L | 20_M | 1.264 | 0.89 |
| 756_I | 804_S | 1.264 | 0.89 |
| 671_N | 674_N | 1.263 | 0.89 |
| 588_K | 646_I | 1.256 | 0.88 |
| 721_L | 740_R | 1.255 | 0.88 |
| 788_R | 813_S | 1.255 | 0.88 |
| 121_K | 429_K | 1.254 | 0.88 |
| 182_I | 192_K | 1.251 | 0.88 |
| 25_L | 732_G | 1.245 | 0.88 |
| 290_T | 344_Q | 1.245 | 0.88 |
| 3_V | 26_M | 1.240 | 0.87 |
| 7_Y | 26_M | 1.239 | 0.87 |
| 848_R | 855_L | 1.233 | 0.87 |
| 21_L | 805_Q | 1.233 | 0.87 |
| 277_F | 352_Q | 1.232 | 0.87 |
| 781_I | 796_W | 1.227 | 0.87 |
| 65_V | 379_G | 1.226 | 0.86 |
| 114_Q | 198_T | 1.225 | 0.86 |
| 781_I | 788_R | 1.225 | 0.86 |
| 25_L | 722_P | 1.222 | 0.86 |
| 4_K | 30_A | 1.219 | 0.86 |
| 426_M | 429_K | 1.219 | 0.86 |
| 432_K | 442_Q | 1.216 | 0.86 |
| 62_D | 607_A | 1.214 | 0.86 |
| 846_R | 852_E | 1.212 | 0.86 |
| 270_V | 393_S | 1.211 | 0.86 |
| 667_A | 671_N | 1.211 | 0.86 |
| 821_A | 833_V | 1.208 | 0.85 |
| 379_G | 444_R | 1.208 | 0.85 |
| 149_M | 152_G | 1.206 | 0.85 |
| 830_I | 833_V | 1.203 | 0.85 |
| 290_T | 337_K | 1.201 | 0.85 |
| 798_N | 809_N | 1.201 | 0.85 |
| 841_R | 853_R | 1.199 | 0.85 |
| 408_T | 413_T | 1.199 | 0.85 |
| 181_I | 192_K | 1.197 | 0.85 |
| 192_K | 195_S | 1.193 | 0.84 |
| 47_E | 85_V | 1.193 | 0.84 |
| 358_T | 615_S | 1.189 | 0.84 |
| 700_A | 764_C | 1.187 | 0.84 |
| 410_G | 413_T | 1.187 | 0.84 |
| 334_S | 446_S | 1.186 | 0.84 |
| 774_L | 797_W | 1.184 | 0.84 |
| 781_I | 809_N | 1.182 | 0.84 |
| 844_P | 855_L | 1.182 | 0.84 |
| 432_K | 567_Q | 1.181 | 0.84 |
| 490_K | 658_Q | 1.176 | 0.83 |
| 1_M | 615_S | 1.174 | 0.83 |
| 812_V | 816_N | 1.174 | 0.83 |
| 764_C | 767_S | 1.172 | 0.83 |
| 178_K | 194_T | 1.171 | 0.83 |
| 102_E | 731_E | 1.170 | 0.83 |
| 26_M | 726_G | 1.169 | 0.83 |
| 853_R | 856_L | 1.169 | 0.83 |
| 676_T | 829_V | 1.166 | 0.83 |
| 229_N | 232_T | 1.165 | 0.82 |
| 843_I | 849_Q | 1.164 | 0.82 |
| 427_W | 435_Y | 1.163 | 0.82 |
| 49_T | 174_A | 1.163 | 0.82 |
| 535_M | 553_N | 1.162 | 0.82 |
| 10_L | 644_S | 1.161 | 0.82 |
| 12_R | 21_L | 1.161 | 0.82 |
| 422_Q | 430_V | 1.159 | 0.82 |
| 646_I | 668_S | 1.158 | 0.82 |
| 346_A | 395_W | 1.157 | 0.82 |
| 756_I | 774_L | 1.155 | 0.82 |
| 315_R | 507_Q | 1.153 | 0.82 |
| 583_V | 588_K | 1.152 | 0.81 |
| 300_N | 442_Q | 1.149 | 0.81 |
| 65_V | 211_E | 1.147 | 0.81 |
| 800_L | 853_R | 1.146 | 0.81 |
| 46_K | 632_D | 1.145 | 0.81 |
| 724_P | 727_P | 1.145 | 0.81 |
| 792_A | 825_G | 1.144 | 0.81 |
| 1_M | 27_I | 1.143 | 0.81 |
| 8_Q | 12_R | 1.143 | 0.81 |
| 612_A | 720_H | 1.143 | 0.81 |
| 640_S | 646_I | 1.142 | 0.81 |
| 595_I | 602_L | 1.142 | 0.81 |
| 269_E | 278_T | 1.141 | 0.81 |
| 306_R | 323_I | 1.138 | 0.80 |
| 1_M | 26_M | 1.138 | 0.80 |
| 583_V | 674_N | 1.136 | 0.80 |
| 275_V | 282_K | 1.136 | 0.80 |
| 471_G | 476_R | 1.136 | 0.80 |
| 135_K | 138_T | 1.135 | 0.80 |
| 844_P | 852_E | 1.133 | 0.80 |
| 8_Q | 21_L | 1.131 | 0.80 |
| 766_F | 773_D | 1.129 | 0.80 |
| 720_H | 796_W | 1.127 | 0.79 |
| 62_D | 68_V | 1.127 | 0.79 |
| 60_A | 65_V | 1.126 | 0.79 |
| 283_T | 288_L | 1.125 | 0.79 |
| 740_R | 747_R | 1.124 | 0.79 |
| 502_K | 735_E | 1.123 | 0.79 |
| 456_R | 466_E | 1.123 | 0.79 |
| 490_K | 651_N | 1.122 | 0.79 |
| 287_Q | 291_S | 1.122 | 0.79 |
| 723_T | 825_G | 1.122 | 0.79 |
| 662_E | 676_T | 1.120 | 0.79 |
| 167_G | 317_F | 1.119 | 0.79 |
| 172_E | 305_K | 1.118 | 0.79 |
| 730_P | 805_Q | 1.116 | 0.79 |
| 7_Y | 756_I | 1.114 | 0.78 |
| 295_N | 444_R | 1.113 | 0.78 |
| 49_T | 659_E | 1.110 | 0.78 |
| 136_N | 139_N | 1.110 | 0.78 |
| 790_W | 795_Y | 1.108 | 0.78 |
| 7_Y | 796_W | 1.107 | 0.78 |
| 350_R | 393_S | 1.104 | 0.78 |
| 798_N | 805_Q | 1.104 | 0.78 |
| 796_W | 812_V | 1.101 | 0.77 |
| 10_L | 21_L | 1.100 | 0.77 |
| 198_T | 425_N | 1.096 | 0.77 |
| 721_L | 804_S | 1.095 | 0.77 |
| 3_V | 615_S | 1.095 | 0.77 |
| 271_V | 277_F | 1.095 | 0.77 |
| 592_L | 614_W | 1.094 | 0.77 |
| 557_R | 564_H | 1.094 | 0.77 |
| 270_V | 778_V | 1.093 | 0.77 |
| 774_L | 796_W | 1.088 | 0.76 |
| 629_M | 632_D | 1.088 | 0.76 |
| 306_R | 319_T | 1.088 | 0.76 |
| 632_D | 640_S | 1.086 | 0.76 |
| 723_T | 740_R | 1.086 | 0.76 |
| 99_D | 440_S | 1.086 | 0.76 |
| 3_V | 614_W | 1.086 | 0.76 |
| 456_R | 459_G | 1.084 | 0.76 |
| 781_I | 804_S | 1.083 | 0.76 |
| 28_C | 614_W | 1.082 | 0.75 |
| 174_A | 429_K | 1.079 | 0.75 |
| 279_D | 282_K | 1.079 | 0.75 |
| 293_E | 297_T | 1.078 | 0.75 |
| 16_R | 30_A | 1.075 | 0.75 |
| 4_K | 8_Q | 1.075 | 0.75 |
| 152_G | 155_K | 1.070 | 0.74 |
| 202_T | 252_R | 1.069 | 0.74 |
| 46_K | 492_E | 1.069 | 0.74 |
| 761_R | 765_L | 1.069 | 0.74 |
| 790_W | 794_K | 1.069 | 0.74 |
| 16_R | 21_L | 1.068 | 0.74 |
| 730_P | 853_R | 1.066 | 0.74 |
| 745_S | 749_V | 1.065 | 0.74 |
| 1_M | 6_K | 1.063 | 0.74 |
| 202_T | 629_M | 1.062 | 0.74 |
| 510_K | 522_F | 1.062 | 0.74 |
| 409_E | 413_T | 1.058 | 0.73 |
| 369_P | 432_K | 1.058 | 0.73 |
| 23_G | 30_A | 1.058 | 0.73 |
| 740_R | 804_S | 1.058 | 0.73 |
| 155_K | 211_E | 1.054 | 0.73 |
| 202_T | 432_K | 1.053 | 0.73 |
| 13_W | 65_V | 1.053 | 0.73 |
| 1_M | 28_C | 1.052 | 0.73 |
| 797_W | 840_I | 1.051 | 0.72 |
| 12_R | 20_M | 1.048 | 0.72 |
| 4_K | 26_M | 1.044 | 0.72 |
| 21_L | 723_T | 1.042 | 0.72 |
| 843_I | 850_G | 1.041 | 0.71 |
| 792_A | 824_E | 1.041 | 0.71 |
| 723_T | 731_E | 1.040 | 0.71 |
| 169_V | 796_W | 1.040 | 0.71 |
| 496_V | 567_Q | 1.038 | 0.71 |
| 775_L | 778_V | 1.036 | 0.71 |
| 192_K | 426_M | 1.036 | 0.71 |
| 753_L | 762_S | 1.035 | 0.71 |
| 293_E | 446_S | 1.035 | 0.71 |
| 370_E | 384_Y | 1.035 | 0.71 |
| 41_G | 45_W | 1.034 | 0.71 |
| 758_D | 762_S | 1.032 | 0.70 |
| 614_W | 725_R | 1.032 | 0.70 |
| 172_E | 200_V | 1.032 | 0.70 |
| 279_D | 476_R | 1.031 | 0.70 |
| 270_V | 395_W | 1.031 | 0.70 |
| 758_D | 775_L | 1.030 | 0.70 |
| 21_L | 26_M | 1.030 | 0.70 |
| 775_L | 800_L | 1.030 | 0.70 |
| 647_E | 654_E | 1.029 | 0.70 |
| 164_S | 200_V | 1.028 | 0.70 |
| 372_V | 432_K | 1.028 | 0.70 |
| 688_I | 693_V | 1.027 | 0.70 |
| 37_T | 41_G | 1.026 | 0.70 |
| 780_R | 784_L | 1.024 | 0.70 |
| 22_L | 490_K | 1.024 | 0.70 |
| 775_L | 797_W | 1.023 | 0.70 |
| 181_I | 211_E | 1.023 | 0.70 |
| 756_I | 797_W | 1.022 | 0.69 |
| 27_I | 30_A | 1.022 | 0.69 |
| 515_I | 519_F | 1.022 | 0.69 |
| 788_R | 825_G | 1.021 | 0.69 |
| 312_G | 315_R | 1.021 | 0.69 |
| 275_V | 437_P | 1.018 | 0.69 |
| 699_F | 702_L | 1.018 | 0.69 |
| 234_N | 275_V | 1.018 | 0.69 |
| 809_N | 853_R | 1.015 | 0.69 |
| 63_T | 774_L | 1.014 | 0.69 |
| 740_R | 775_L | 1.014 | 0.69 |
| 845_R | 848_R | 1.014 | 0.69 |
| 721_L | 784_L | 1.014 | 0.69 |
| 723_T | 824_E | 1.013 | 0.68 |
| 211_E | 287_Q | 1.013 | 0.68 |
| 721_L | 775_L | 1.013 | 0.68 |
| 13_W | 836_A | 1.012 | 0.68 |
| 12_R | 22_L | 1.010 | 0.68 |
| 195_S | 315_R | 1.010 | 0.68 |
| 85_V | 646_I | 1.009 | 0.68 |
| 805_Q | 816_N | 1.009 | 0.68 |
| 464_E | 467_I | 1.009 | 0.68 |
| 154_I | 173_Y | 1.009 | 0.68 |
| 65_V | 429_K | 1.008 | 0.68 |
| 851_L | 856_L | 1.007 | 0.68 |
| 271_V | 315_R | 1.007 | 0.68 |
| 25_L | 49_T | 1.006 | 0.68 |
| 157_C | 162_S | 1.004 | 0.67 |
| 287_Q | 595_I | 1.004 | 0.67 |
| 843_I | 846_R | 1.003 | 0.67 |
| 425_N | 502_K | 1.003 | 0.67 |
| 159_F | 567_Q | 1.002 | 0.67 |
| 803_W | 806_E | 1.002 | 0.67 |
| 84_V | 651_N | 1.000 | 0.67 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- See coupling matrix (for protein design or mutagenesis)
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 4tvpG | 1 | 0.5257 | 100 | 0.445 | Contact Map |
| 4r4hA | 1 | 0.3925 | 100 | 0.491 | Contact Map |
| 4jzzA | 1 | 0.3925 | 100 | 0.565 | Contact Map |
| 3lqaG | 1 | 0.3353 | 100 | 0.637 | Contact Map |
| 2bf1A | 1 | 0.3458 | 100 | 0.646 | Contact Map |
| 4i3sG | 1 | 0.2103 | 100 | 0.822 | Contact Map |
| 4tvpB | 1 | 0.1472 | 100 | 0.826 | Contact Map |
| 3tygA | 1 | 0.1822 | 100 | 0.85 | Contact Map |
| 1qbzA | 3 | 0.1402 | 100 | 0.861 | Contact Map |
| 4jpkA | 1 | 0.1869 | 100 | 0.877 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)