| betagal |
| ID: | 1486089593 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 992 (973) | ||
| Sequences: | 1937 (1378.3) | ||
| Seq/Len: | 1.991 | ||
| Nf(neff/√len): | 44.2 |
HHblits Results: (2016_02)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 1.991).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 42_N | 198_D | 5.325 | 1.00 |
| 289_S | 292_I | 4.353 | 1.00 |
| 146_V | 163_F | 4.112 | 1.00 |
| 356_E | 384_L | 3.937 | 1.00 |
| 373_A | 553_F | 3.798 | 1.00 |
| 46_R | 70_T | 3.527 | 1.00 |
| 887_L | 927_G | 3.521 | 1.00 |
| 324_I | 470_P | 3.510 | 1.00 |
| 316_D | 391_R | 3.404 | 1.00 |
| 616_F | 687_V | 3.370 | 1.00 |
| 432_Q | 465_V | 3.281 | 1.00 |
| 686_R | 701_I | 3.248 | 1.00 |
| 897_L | 927_G | 3.239 | 1.00 |
| 432_Q | 435_R | 3.236 | 1.00 |
| 75_S | 80_H | 3.222 | 1.00 |
| 442_I | 485_I | 3.186 | 1.00 |
| 431_V | 462_I | 3.159 | 1.00 |
| 216_T | 225_A | 3.150 | 1.00 |
| 349_L | 563_I | 3.101 | 1.00 |
| 680_Q | 929_R | 3.051 | 1.00 |
| 463_K | 471_V | 3.020 | 1.00 |
| 286_K | 294_N | 3.014 | 1.00 |
| 692_A | 697_E | 2.996 | 1.00 |
| 912_M | 925_R | 2.991 | 1.00 |
| 128_I | 139_L | 2.966 | 1.00 |
| 427_V | 462_I | 2.817 | 1.00 |
| 360_V | 391_R | 2.800 | 1.00 |
| 369_N | 604_L | 2.791 | 1.00 |
| 544_R | 628_E | 2.770 | 1.00 |
| 94_I | 182_S | 2.705 | 1.00 |
| 461_W | 465_V | 2.694 | 1.00 |
| 374_V | 394_L | 2.694 | 1.00 |
| 587_Q | 777_D | 2.690 | 1.00 |
| 141_C | 171_L | 2.623 | 1.00 |
| 217_R | 321_E | 2.612 | 1.00 |
| 581_D | 584_N | 2.576 | 1.00 |
| 890_Q | 899_A | 2.572 | 1.00 |
| 133_V | 137_F | 2.563 | 1.00 |
| 537_A | 541_Q | 2.553 | 1.00 |
| 641_W | 653_G | 2.513 | 1.00 |
| 623_I | 685_V | 2.495 | 1.00 |
| 374_V | 385_W | 2.491 | 1.00 |
| 556_D | 560_Q | 2.486 | 1.00 |
| 556_D | 591_N | 2.480 | 1.00 |
| 754_Q | 761_K | 2.475 | 1.00 |
| 689_Q | 696_S | 2.448 | 1.00 |
| 304_T | 308_T | 2.440 | 1.00 |
| 360_V | 364_L | 2.438 | 1.00 |
| 459_Y | 463_K | 2.423 | 1.00 |
| 883_N | 906_D | 2.408 | 1.00 |
| 124_G | 203_H | 2.390 | 1.00 |
| 244_T | 303_H | 2.381 | 1.00 |
| 71_V | 80_H | 2.341 | 1.00 |
| 125_Q | 159_D | 2.321 | 1.00 |
| 44_E | 70_T | 2.320 | 1.00 |
| 290_A | 395_Y | 2.304 | 1.00 |
| 347_H | 358_T | 2.289 | 1.00 |
| 622_T | 666_L | 2.274 | 1.00 |
| 136_A | 179_S | 2.265 | 1.00 |
| 11_L | 145_W | 2.237 | 1.00 |
| 72_V | 80_H | 2.232 | 1.00 |
| 363_I | 394_L | 2.228 | 1.00 |
| 25_N | 28_E | 2.227 | 1.00 |
| 578_D | 959_H | 2.224 | 1.00 |
| 363_I | 392_Y | 2.202 | 1.00 |
| 420_L | 457_A | 2.191 | 1.00 |
| 130_F | 173_V | 2.191 | 1.00 |
| 554_V | 607_A | 2.189 | 1.00 |
| 149_G | 156_S | 2.178 | 1.00 |
| 883_N | 932_N | 2.177 | 1.00 |
| 738_L | 741_K | 2.166 | 0.99 |
| 350_H | 353_V | 2.151 | 0.99 |
| 329_L | 441_I | 2.139 | 0.99 |
| 875_L | 971_L | 2.139 | 0.99 |
| 111_S | 170_R | 2.138 | 0.99 |
| 117_D | 120_W | 2.132 | 0.99 |
| 427_V | 458_L | 2.122 | 0.99 |
| 247_L | 317_V | 2.117 | 0.99 |
| 331_L | 336_L | 2.104 | 0.99 |
| 369_N | 605_T | 2.100 | 0.99 |
| 69_D | 82_Y | 2.093 | 0.99 |
| 612_Q | 703_A | 2.087 | 0.99 |
| 639_L | 687_V | 2.081 | 0.99 |
| 873_C | 971_L | 2.079 | 0.99 |
| 528_A | 533_L | 2.069 | 0.99 |
| 414_T | 423_M | 2.065 | 0.99 |
| 350_H | 355_D | 2.062 | 0.99 |
| 644_A | 903_D | 2.062 | 0.99 |
| 390_D | 437_H | 2.057 | 0.99 |
| 491_A | 522_L | 2.055 | 0.99 |
| 126_T | 164_L | 2.043 | 0.99 |
| 640_H | 688_V | 2.041 | 0.99 |
| 883_N | 904_R | 2.030 | 0.99 |
| 224_R | 287_L | 2.025 | 0.99 |
| 424_S | 461_W | 2.006 | 0.99 |
| 398_D | 430_M | 1.994 | 0.99 |
| 227_L | 319_F | 1.988 | 0.99 |
| 617_R | 624_E | 1.987 | 0.99 |
| 924_L | 943_Q | 1.983 | 0.99 |
| 624_E | 664_K | 1.983 | 0.99 |
| 59_S | 62_E | 1.979 | 0.99 |
| 343_R | 381_N | 1.977 | 0.99 |
| 225_A | 285_P | 1.972 | 0.99 |
| 609_H | 705_Q | 1.971 | 0.99 |
| 882_V | 912_M | 1.970 | 0.99 |
| 590_M | 917_V | 1.965 | 0.99 |
| 338_I | 441_I | 1.964 | 0.99 |
| 297_R | 316_D | 1.945 | 0.99 |
| 137_F | 149_G | 1.936 | 0.99 |
| 26_S | 246_S | 1.926 | 0.99 |
| 608_K | 701_I | 1.925 | 0.99 |
| 14_L | 127_R | 1.924 | 0.99 |
| 630_L | 662_Q | 1.917 | 0.98 |
| 67_E | 111_S | 1.910 | 0.98 |
| 682_W | 902_F | 1.908 | 0.98 |
| 398_D | 434_D | 1.905 | 0.98 |
| 282_V | 285_P | 1.901 | 0.98 |
| 645_L | 679_G | 1.898 | 0.98 |
| 560_Q | 591_N | 1.887 | 0.98 |
| 746_N | 753_S | 1.885 | 0.98 |
| 141_C | 160_L | 1.884 | 0.98 |
| 224_R | 283_E | 1.884 | 0.98 |
| 109_C | 172_A | 1.866 | 0.98 |
| 643_V | 709_L | 1.853 | 0.98 |
| 219_N | 224_R | 1.850 | 0.98 |
| 363_I | 385_W | 1.849 | 0.98 |
| 614_F | 634_S | 1.842 | 0.98 |
| 887_L | 897_L | 1.831 | 0.98 |
| 128_I | 160_L | 1.829 | 0.98 |
| 218_F | 222_F | 1.814 | 0.98 |
| 566_D | 570_N | 1.813 | 0.98 |
| 301_E | 309_L | 1.812 | 0.98 |
| 489_M | 523_C | 1.812 | 0.98 |
| 931_L | 944_F | 1.807 | 0.98 |
| 626_T | 664_K | 1.806 | 0.98 |
| 704_W | 901_C | 1.805 | 0.98 |
| 928_T | 944_F | 1.805 | 0.98 |
| 908_P | 911_D | 1.799 | 0.97 |
| 595_F | 914_T | 1.791 | 0.97 |
| 526_A | 533_L | 1.789 | 0.97 |
| 644_A | 684_T | 1.786 | 0.97 |
| 558_V | 598_R | 1.786 | 0.97 |
| 595_F | 599_T | 1.777 | 0.97 |
| 142_N | 169_N | 1.771 | 0.97 |
| 574_A | 579_F | 1.756 | 0.97 |
| 872_N | 952_Q | 1.754 | 0.97 |
| 212_F | 300_V | 1.749 | 0.97 |
| 366_M | 394_L | 1.745 | 0.97 |
| 2_D | 5_N | 1.745 | 0.97 |
| 928_T | 942_F | 1.724 | 0.96 |
| 430_M | 440_V | 1.722 | 0.96 |
| 563_I | 571_P | 1.718 | 0.96 |
| 14_L | 159_D | 1.715 | 0.96 |
| 522_L | 543_F | 1.713 | 0.96 |
| 396_V | 439_S | 1.711 | 0.96 |
| 435_R | 465_V | 1.699 | 0.96 |
| 219_N | 287_L | 1.689 | 0.96 |
| 10_Q | 13_R | 1.684 | 0.96 |
| 451_H | 482_A | 1.677 | 0.96 |
| 607_A | 611_Q | 1.672 | 0.96 |
| 216_T | 285_P | 1.672 | 0.96 |
| 573_S | 596_A | 1.669 | 0.96 |
| 325_E | 330_L | 1.662 | 0.95 |
| 245_V | 300_V | 1.661 | 0.95 |
| 904_R | 930_E | 1.654 | 0.95 |
| 684_T | 706_Q | 1.653 | 0.95 |
| 213_H | 435_R | 1.651 | 0.95 |
| 347_H | 355_D | 1.649 | 0.95 |
| 150_Q | 180_D | 1.646 | 0.95 |
| 533_L | 536_F | 1.646 | 0.95 |
| 561_S | 596_A | 1.642 | 0.95 |
| 497_Q | 542_A | 1.641 | 0.95 |
| 298_A | 317_V | 1.640 | 0.95 |
| 377_S | 381_N | 1.639 | 0.95 |
| 521_I | 550_Q | 1.636 | 0.95 |
| 339_R | 613_F | 1.632 | 0.95 |
| 44_E | 72_V | 1.628 | 0.95 |
| 130_F | 133_V | 1.627 | 0.95 |
| 565_Y | 571_P | 1.608 | 0.94 |
| 497_Q | 545_Q | 1.607 | 0.94 |
| 950_S | 970_W | 1.603 | 0.94 |
| 365_L | 557_W | 1.600 | 0.94 |
| 209_I | 231_V | 1.598 | 0.94 |
| 526_A | 536_F | 1.594 | 0.94 |
| 72_V | 75_S | 1.586 | 0.94 |
| 244_T | 301_E | 1.585 | 0.94 |
| 770_Q | 972_N | 1.585 | 0.94 |
| 624_E | 666_L | 1.569 | 0.93 |
| 381_N | 386_Y | 1.568 | 0.93 |
| 609_H | 612_Q | 1.565 | 0.93 |
| 701_I | 901_C | 1.562 | 0.93 |
| 141_C | 146_V | 1.562 | 0.93 |
| 361_Q | 364_L | 1.561 | 0.93 |
| 472_Q | 487_C | 1.561 | 0.93 |
| 938_W | 971_L | 1.561 | 0.93 |
| 642_M | 686_R | 1.557 | 0.93 |
| 79_M | 562_L | 1.556 | 0.93 |
| 371_F | 607_A | 1.550 | 0.93 |
| 211_D | 435_R | 1.547 | 0.93 |
| 39_R | 117_D | 1.546 | 0.93 |
| 355_D | 358_T | 1.540 | 0.92 |
| 910_S | 948_R | 1.535 | 0.92 |
| 331_L | 441_I | 1.533 | 0.92 |
| 428_T | 461_W | 1.532 | 0.92 |
| 329_L | 338_I | 1.529 | 0.92 |
| 645_L | 681_L | 1.522 | 0.92 |
| 729_T | 747_R | 1.512 | 0.91 |
| 902_F | 941_D | 1.510 | 0.91 |
| 897_L | 926_C | 1.505 | 0.91 |
| 907_L | 912_M | 1.505 | 0.91 |
| 248_W | 299_V | 1.499 | 0.91 |
| 131_D | 200_S | 1.495 | 0.91 |
| 873_C | 973_I | 1.489 | 0.91 |
| 125_Q | 206_T | 1.476 | 0.90 |
| 60_W | 172_A | 1.467 | 0.90 |
| 773_R | 779_D | 1.464 | 0.90 |
| 953_Q | 966_E | 1.456 | 0.89 |
| 629_Y | 636_N | 1.456 | 0.89 |
| 614_F | 687_V | 1.454 | 0.89 |
| 362_D | 598_R | 1.449 | 0.89 |
| 56_V | 174_M | 1.448 | 0.89 |
| 360_V | 384_L | 1.446 | 0.89 |
| 112_L | 171_L | 1.441 | 0.89 |
| 37_Q | 124_G | 1.441 | 0.89 |
| 204_K | 311_E | 1.436 | 0.88 |
| 13_R | 16_A | 1.435 | 0.88 |
| 384_L | 387_T | 1.434 | 0.88 |
| 292_I | 632_R | 1.431 | 0.88 |
| 14_L | 210_S | 1.430 | 0.88 |
| 892_N | 900_A | 1.425 | 0.88 |
| 660_A | 663_G | 1.423 | 0.88 |
| 78_Q | 193_S | 1.421 | 0.88 |
| 341_V | 593_L | 1.420 | 0.88 |
| 245_V | 298_A | 1.419 | 0.88 |
| 213_H | 465_V | 1.417 | 0.88 |
| 613_F | 629_Y | 1.416 | 0.87 |
| 151_D | 401_N | 1.406 | 0.87 |
| 139_L | 171_L | 1.406 | 0.87 |
| 566_D | 961_H | 1.403 | 0.87 |
| 2_D | 138_H | 1.394 | 0.86 |
| 356_E | 360_V | 1.393 | 0.86 |
| 896_R | 980_I | 1.392 | 0.86 |
| 214_V | 298_A | 1.390 | 0.86 |
| 2_D | 11_L | 1.387 | 0.86 |
| 6_P | 418_R | 1.386 | 0.86 |
| 743_W | 752_L | 1.385 | 0.86 |
| 286_K | 292_I | 1.383 | 0.86 |
| 564_K | 574_A | 1.380 | 0.86 |
| 359_M | 385_W | 1.376 | 0.85 |
| 250_G | 294_N | 1.372 | 0.85 |
| 767_L | 873_C | 1.368 | 0.85 |
| 329_L | 470_P | 1.368 | 0.85 |
| 225_A | 287_L | 1.365 | 0.85 |
| 459_Y | 471_V | 1.365 | 0.85 |
| 76_N | 353_V | 1.365 | 0.85 |
| 596_A | 917_V | 1.360 | 0.84 |
| 415_D | 453_A | 1.351 | 0.84 |
| 774_A | 954_L | 1.351 | 0.84 |
| 982_G | 986_W | 1.349 | 0.84 |
| 609_H | 704_W | 1.348 | 0.84 |
| 593_L | 604_L | 1.345 | 0.84 |
| 907_L | 911_D | 1.342 | 0.83 |
| 497_Q | 501_A | 1.337 | 0.83 |
| 880_E | 948_R | 1.337 | 0.83 |
| 218_F | 287_L | 1.331 | 0.83 |
| 533_L | 603_A | 1.331 | 0.83 |
| 366_M | 371_F | 1.329 | 0.83 |
| 390_D | 439_S | 1.329 | 0.83 |
| 931_L | 971_L | 1.324 | 0.82 |
| 431_V | 461_W | 1.322 | 0.82 |
| 9_T | 425_E | 1.320 | 0.82 |
| 521_I | 553_F | 1.320 | 0.82 |
| 872_N | 972_N | 1.312 | 0.81 |
| 360_V | 363_I | 1.311 | 0.81 |
| 890_Q | 900_A | 1.310 | 0.81 |
| 209_I | 313_E | 1.309 | 0.81 |
| 770_Q | 951_Q | 1.307 | 0.81 |
| 366_M | 557_W | 1.297 | 0.80 |
| 246_S | 301_E | 1.294 | 0.80 |
| 397_V | 442_I | 1.294 | 0.80 |
| 368_Q | 700_H | 1.291 | 0.80 |
| 92_Y | 406_G | 1.287 | 0.80 |
| 926_C | 943_Q | 1.285 | 0.80 |
| 77_W | 108_G | 1.285 | 0.80 |
| 682_W | 708_R | 1.285 | 0.80 |
| 63_C | 165_R | 1.282 | 0.79 |
| 109_C | 174_M | 1.280 | 0.79 |
| 47_F | 108_G | 1.279 | 0.79 |
| 557_W | 604_L | 1.278 | 0.79 |
| 341_V | 371_F | 1.275 | 0.79 |
| 741_K | 845_I | 1.274 | 0.79 |
| 154_L | 430_M | 1.272 | 0.79 |
| 371_F | 611_Q | 1.271 | 0.79 |
| 113_T | 168_E | 1.271 | 0.79 |
| 946_I | 971_L | 1.268 | 0.78 |
| 127_R | 159_D | 1.268 | 0.78 |
| 882_V | 944_F | 1.267 | 0.78 |
| 488_P | 491_A | 1.267 | 0.78 |
| 334_K | 662_Q | 1.263 | 0.78 |
| 126_T | 203_H | 1.261 | 0.78 |
| 395_Y | 631_F | 1.258 | 0.78 |
| 303_H | 309_L | 1.258 | 0.78 |
| 88_T | 93_P | 1.257 | 0.77 |
| 184_L | 422_A | 1.256 | 0.77 |
| 472_Q | 523_C | 1.253 | 0.77 |
| 891_E | 916_Y | 1.250 | 0.77 |
| 1_R | 4_E | 1.248 | 0.77 |
| 398_D | 433_R | 1.246 | 0.77 |
| 488_P | 495_E | 1.245 | 0.76 |
| 642_M | 684_T | 1.243 | 0.76 |
| 345_E | 385_W | 1.242 | 0.76 |
| 629_Y | 632_R | 1.240 | 0.76 |
| 537_A | 898_T | 1.234 | 0.76 |
| 136_A | 148_Y | 1.234 | 0.76 |
| 740_N | 758_G | 1.221 | 0.75 |
| 216_T | 468_S | 1.220 | 0.74 |
| 457_A | 460_R | 1.220 | 0.74 |
| 151_D | 429_R | 1.220 | 0.74 |
| 615_Q | 628_E | 1.215 | 0.74 |
| 910_S | 965_A | 1.214 | 0.74 |
| 902_F | 929_R | 1.214 | 0.74 |
| 420_L | 424_S | 1.213 | 0.74 |
| 423_M | 449_S | 1.210 | 0.74 |
| 230_E | 277_T | 1.209 | 0.73 |
| 632_R | 661_P | 1.208 | 0.73 |
| 56_V | 109_C | 1.208 | 0.73 |
| 420_L | 453_A | 1.207 | 0.73 |
| 449_S | 473_Y | 1.207 | 0.73 |
| 894_P | 977_H | 1.203 | 0.73 |
| 331_L | 395_Y | 1.202 | 0.73 |
| 927_G | 941_D | 1.198 | 0.73 |
| 134_N | 352_Q | 1.198 | 0.73 |
| 374_V | 389_C | 1.197 | 0.72 |
| 689_Q | 699_G | 1.196 | 0.72 |
| 52_A | 55_A | 1.196 | 0.72 |
| 299_V | 314_A | 1.194 | 0.72 |
| 364_L | 368_Q | 1.193 | 0.72 |
| 564_K | 572_W | 1.193 | 0.72 |
| 617_R | 626_T | 1.192 | 0.72 |
| 212_F | 315_C | 1.190 | 0.72 |
| 9_T | 421_P | 1.190 | 0.72 |
| 19_P | 383_P | 1.189 | 0.72 |
| 933_Y | 971_L | 1.187 | 0.72 |
| 431_V | 465_V | 1.185 | 0.71 |
| 130_F | 137_F | 1.183 | 0.71 |
| 385_W | 389_C | 1.183 | 0.71 |
| 922_N | 947_S | 1.183 | 0.71 |
| 159_D | 164_L | 1.181 | 0.71 |
| 984_D | 987_S | 1.176 | 0.71 |
| 465_V | 468_S | 1.176 | 0.71 |
| 486_I | 518_R | 1.175 | 0.70 |
| 946_I | 969_T | 1.172 | 0.70 |
| 154_L | 429_R | 1.170 | 0.70 |
| 218_F | 225_A | 1.164 | 0.69 |
| 215_A | 468_S | 1.163 | 0.69 |
| 493_V | 542_A | 1.161 | 0.69 |
| 337_L | 550_Q | 1.159 | 0.69 |
| 402_I | 458_L | 1.156 | 0.69 |
| 907_L | 925_R | 1.154 | 0.68 |
| 78_Q | 134_N | 1.154 | 0.68 |
| 500_P | 549_L | 1.153 | 0.68 |
| 844_R | 854_T | 1.153 | 0.68 |
| 427_V | 430_M | 1.151 | 0.68 |
| 882_V | 925_R | 1.149 | 0.68 |
| 113_T | 170_R | 1.149 | 0.68 |
| 216_T | 321_E | 1.148 | 0.68 |
| 56_V | 107_T | 1.147 | 0.68 |
| 290_A | 631_F | 1.145 | 0.68 |
| 38_L | 200_S | 1.145 | 0.68 |
| 47_F | 77_W | 1.144 | 0.67 |
| 133_V | 139_L | 1.144 | 0.67 |
| 385_W | 396_V | 1.143 | 0.67 |
| 868_R | 974_D | 1.140 | 0.67 |
| 284_N | 287_L | 1.140 | 0.67 |
| 532_S | 982_G | 1.135 | 0.67 |
| 16_A | 429_R | 1.134 | 0.66 |
| 846_D | 850_Q | 1.134 | 0.66 |
| 639_L | 655_V | 1.130 | 0.66 |
| 680_Q | 902_F | 1.129 | 0.66 |
| 623_I | 683_L | 1.127 | 0.66 |
| 17_H | 157_E | 1.127 | 0.66 |
| 595_F | 915_P | 1.127 | 0.66 |
| 50_F | 109_C | 1.125 | 0.66 |
| 949_Y | 963_L | 1.122 | 0.65 |
| 575_Y | 959_H | 1.121 | 0.65 |
| 488_P | 520_L | 1.121 | 0.65 |
| 83_D | 106_P | 1.116 | 0.65 |
| 496_D | 549_L | 1.114 | 0.64 |
| 572_W | 961_H | 1.112 | 0.64 |
| 328_L | 550_Q | 1.107 | 0.64 |
| 938_W | 973_I | 1.105 | 0.64 |
| 659_V | 665_Q | 1.105 | 0.64 |
| 111_S | 172_A | 1.104 | 0.63 |
| 67_E | 170_R | 1.098 | 0.63 |
| 369_N | 600_P | 1.097 | 0.63 |
| 160_L | 201_L | 1.096 | 0.63 |
| 368_Q | 696_S | 1.096 | 0.63 |
| 222_F | 333_G | 1.096 | 0.63 |
| 214_V | 229_A | 1.096 | 0.63 |
| 228_E | 279_R | 1.095 | 0.62 |
| 216_T | 287_L | 1.094 | 0.62 |
| 225_A | 321_E | 1.092 | 0.62 |
| 215_A | 230_E | 1.092 | 0.62 |
| 133_V | 195_I | 1.090 | 0.62 |
| 701_I | 704_W | 1.089 | 0.62 |
| 213_H | 468_S | 1.087 | 0.62 |
| 209_I | 300_V | 1.086 | 0.62 |
| 71_V | 75_S | 1.086 | 0.62 |
| 24_R | 28_E | 1.080 | 0.61 |
| 563_I | 573_S | 1.080 | 0.61 |
| 135_S | 179_S | 1.080 | 0.61 |
| 225_A | 319_F | 1.080 | 0.61 |
| 155_P | 433_R | 1.078 | 0.61 |
| 638_L | 654_E | 1.078 | 0.61 |
| 387_T | 437_H | 1.077 | 0.61 |
| 349_L | 571_P | 1.076 | 0.60 |
| 546_Y | 549_L | 1.076 | 0.60 |
| 642_M | 649_P | 1.076 | 0.60 |
| 28_E | 36_Q | 1.074 | 0.60 |
| 622_T | 668_E | 1.071 | 0.60 |
| 885_L | 902_F | 1.070 | 0.60 |
| 561_S | 590_M | 1.066 | 0.59 |
| 222_F | 287_L | 1.061 | 0.59 |
| 329_L | 442_I | 1.061 | 0.59 |
| 138_H | 145_W | 1.060 | 0.59 |
| 327_G | 548_R | 1.059 | 0.59 |
| 133_V | 175_V | 1.059 | 0.59 |
| 456_D | 482_A | 1.056 | 0.58 |
| 226_V | 279_R | 1.055 | 0.58 |
| 924_L | 977_H | 1.055 | 0.58 |
| 466_D | 469_R | 1.053 | 0.58 |
| 770_Q | 872_N | 1.053 | 0.58 |
| 287_L | 319_F | 1.051 | 0.58 |
| 219_N | 222_F | 1.050 | 0.58 |
| 229_A | 245_V | 1.046 | 0.57 |
| 881_R | 906_D | 1.045 | 0.57 |
| 456_D | 460_R | 1.044 | 0.57 |
| 708_R | 902_F | 1.043 | 0.57 |
| 776_L | 779_D | 1.041 | 0.57 |
| 83_D | 177_R | 1.037 | 0.56 |
| 155_P | 383_P | 1.036 | 0.56 |
| 649_P | 652_S | 1.035 | 0.56 |
| 633_H | 660_A | 1.033 | 0.56 |
| 116_V | 160_L | 1.029 | 0.55 |
| 135_S | 181_G | 1.029 | 0.55 |
| 865_H | 978_M | 1.028 | 0.55 |
| 878_V | 935_P | 1.025 | 0.55 |
| 359_M | 374_V | 1.024 | 0.55 |
| 983_D | 986_W | 1.022 | 0.55 |
| 217_R | 225_A | 1.021 | 0.54 |
| 215_A | 228_E | 1.020 | 0.54 |
| 743_W | 845_I | 1.019 | 0.54 |
| 190_W | 346_H | 1.018 | 0.54 |
| 359_M | 363_I | 1.017 | 0.54 |
| 496_D | 522_L | 1.014 | 0.54 |
| 745_F | 752_L | 1.014 | 0.54 |
| 913_Y | 947_S | 1.013 | 0.54 |
| 322_V | 329_L | 1.013 | 0.54 |
| 529_M | 588_F | 1.012 | 0.53 |
| 60_W | 65_L | 1.009 | 0.53 |
| 137_F | 173_V | 1.008 | 0.53 |
| 887_L | 926_C | 1.005 | 0.53 |
| 633_H | 661_P | 1.005 | 0.53 |
| 107_T | 176_L | 1.005 | 0.53 |
| 451_H | 456_D | 1.004 | 0.53 |
| 184_L | 404_T | 1.001 | 0.52 |
| 226_V | 281_N | 1.000 | 0.52 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 1jz7A | 4 | 0.998 | 100 | 0.238 | Contact Map |
| 3bgaA | 2 | 0.9506 | 100 | 0.284 | Contact Map |
| 3obaA | 4 | 0.9425 | 100 | 0.303 | Contact Map |
| 1yq2A | 6 | 0.9415 | 100 | 0.319 | Contact Map |
| 3cmgA | 1 | 0.6089 | 100 | 0.687 | Contact Map |
| 4ypjA | 2 | 0 | 100 | 0.688 | Contact Map |
| 3fn9A | 4 | 0.6129 | 100 | 0.69 | Contact Map |
| 3gm8A | 1 | 0.6774 | 100 | 0.697 | Contact Map |
| 3hn3A | 4 | 0.5413 | 100 | 0.705 | Contact Map |
| 3lpfA | 2 | 0.5433 | 100 | 0.714 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)