| 445sequences-1e-4-iterations4-coverage90-hhblits -force run |
| ID: | 1441680894 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 975 (974) | ||
| Sequences: | 129 (65.4) | ||
| Seq/Len: | 0.132 | ||
| Nf(neff/√len): | 2.1 |
HHblits Results: (2015_06)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 0.132).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 772_I | 789_K | 2.067 | 0.52 |
| 251_D | 355_V | 1.891 | 0.43 |
| 772_I | 826_I | 1.862 | 0.41 |
| 268_V | 460_C | 1.810 | 0.39 |
| 276_F | 329_T | 1.708 | 0.34 |
| 376_M | 457_Y | 1.703 | 0.33 |
| 741_R | 797_L | 1.654 | 0.31 |
| 439_F | 519_C | 1.641 | 0.30 |
| 442_A | 865_Y | 1.636 | 0.30 |
| 439_F | 522_N | 1.617 | 0.29 |
| 32_E | 536_P | 1.607 | 0.29 |
| 209_F | 828_V | 1.604 | 0.29 |
| 645_I | 881_V | 1.590 | 0.28 |
| 432_R | 549_T | 1.587 | 0.28 |
| 80_Y | 259_K | 1.582 | 0.28 |
| 84_F | 486_K | 1.576 | 0.28 |
| 91_C | 330_V | 1.576 | 0.28 |
| 829_E | 893_T | 1.561 | 0.27 |
| 567_C | 870_L | 1.553 | 0.27 |
| 80_Y | 454_V | 1.528 | 0.26 |
| 162_C | 306_Y | 1.514 | 0.25 |
| 904_E | 907_R | 1.482 | 0.24 |
| 846_P | 958_P | 1.479 | 0.24 |
| 270_R | 828_V | 1.472 | 0.23 |
| 227_L | 753_N | 1.447 | 0.22 |
| 276_F | 546_I | 1.444 | 0.22 |
| 427_L | 780_S | 1.439 | 0.22 |
| 279_Y | 828_V | 1.439 | 0.22 |
| 76_H | 202_S | 1.433 | 0.22 |
| 498_A | 587_L | 1.433 | 0.22 |
| 267_Y | 510_E | 1.432 | 0.22 |
| 276_F | 428_D | 1.429 | 0.22 |
| 522_N | 872_E | 1.428 | 0.22 |
| 389_L | 826_I | 1.415 | 0.21 |
| 664_D | 741_R | 1.413 | 0.21 |
| 477_S | 751_H | 1.411 | 0.21 |
| 482_L | 958_P | 1.410 | 0.21 |
| 514_I | 826_I | 1.408 | 0.21 |
| 423_L | 752_D | 1.390 | 0.20 |
| 412_G | 970_I | 1.390 | 0.20 |
| 227_L | 751_H | 1.380 | 0.20 |
| 929_N | 970_I | 1.379 | 0.20 |
| 71_D | 213_I | 1.376 | 0.20 |
| 308_L | 498_A | 1.376 | 0.20 |
| 70_I | 267_Y | 1.374 | 0.20 |
| 439_F | 466_N | 1.371 | 0.20 |
| 48_H | 80_Y | 1.365 | 0.19 |
| 342_C | 631_C | 1.359 | 0.19 |
| 392_N | 788_H | 1.357 | 0.19 |
| 318_L | 344_P | 1.357 | 0.19 |
| 685_P | 893_T | 1.356 | 0.19 |
| 276_F | 741_R | 1.354 | 0.19 |
| 453_L | 489_I | 1.347 | 0.19 |
| 591_C | 817_I | 1.346 | 0.19 |
| 213_I | 896_E | 1.337 | 0.18 |
| 223_A | 837_G | 1.325 | 0.18 |
| 85_Y | 513_L | 1.324 | 0.18 |
| 354_L | 753_N | 1.319 | 0.18 |
| 32_E | 39_K | 1.316 | 0.18 |
| 646_I | 848_D | 1.312 | 0.18 |
| 80_Y | 221_A | 1.305 | 0.17 |
| 71_D | 104_R | 1.305 | 0.17 |
| 347_P | 684_D | 1.305 | 0.17 |
| 578_T | 743_I | 1.305 | 0.17 |
| 252_F | 281_L | 1.303 | 0.17 |
| 404_F | 859_E | 1.301 | 0.17 |
| 276_F | 965_L | 1.296 | 0.17 |
| 42_G | 170_V | 1.295 | 0.17 |
| 188_I | 484_K | 1.295 | 0.17 |
| 102_I | 277_N | 1.293 | 0.17 |
| 277_N | 346_K | 1.292 | 0.17 |
| 405_K | 514_I | 1.287 | 0.17 |
| 331_R | 412_G | 1.286 | 0.17 |
| 188_I | 578_T | 1.285 | 0.17 |
| 684_D | 830_N | 1.285 | 0.17 |
| 446_S | 958_P | 1.283 | 0.17 |
| 574_L | 686_T | 1.283 | 0.17 |
| 753_N | 874_K | 1.282 | 0.17 |
| 628_I | 815_R | 1.280 | 0.17 |
| 132_I | 223_A | 1.277 | 0.17 |
| 751_H | 878_A | 1.275 | 0.17 |
| 269_L | 627_L | 1.275 | 0.17 |
| 279_Y | 657_Y | 1.270 | 0.16 |
| 253_A | 282_T | 1.267 | 0.16 |
| 349_D | 467_I | 1.263 | 0.16 |
| 52_A | 120_G | 1.262 | 0.16 |
| 201_S | 948_E | 1.257 | 0.16 |
| 84_F | 945_I | 1.257 | 0.16 |
| 244_C | 588_W | 1.256 | 0.16 |
| 351_S | 567_C | 1.254 | 0.16 |
| 424_L | 694_K | 1.253 | 0.16 |
| 37_A | 776_L | 1.253 | 0.16 |
| 119_P | 175_A | 1.252 | 0.16 |
| 223_A | 354_L | 1.246 | 0.16 |
| 52_A | 404_F | 1.244 | 0.16 |
| 242_S | 582_S | 1.243 | 0.16 |
| 438_F | 785_L | 1.243 | 0.16 |
| 585_T | 758_K | 1.243 | 0.16 |
| 435_S | 855_K | 1.242 | 0.16 |
| 96_R | 741_R | 1.239 | 0.16 |
| 276_F | 426_V | 1.238 | 0.15 |
| 445_M | 559_R | 1.231 | 0.15 |
| 424_L | 709_M | 1.228 | 0.15 |
| 518_V | 746_L | 1.228 | 0.15 |
| 244_C | 867_P | 1.227 | 0.15 |
| 446_S | 453_L | 1.227 | 0.15 |
| 140_I | 922_L | 1.226 | 0.15 |
| 389_L | 892_F | 1.224 | 0.15 |
| 12_S | 166_N | 1.223 | 0.15 |
| 194_K | 943_Y | 1.222 | 0.15 |
| 158_L | 780_S | 1.222 | 0.15 |
| 355_V | 550_V | 1.221 | 0.15 |
| 518_V | 905_F | 1.221 | 0.15 |
| 39_K | 46_V | 1.219 | 0.15 |
| 482_L | 876_S | 1.218 | 0.15 |
| 439_F | 872_E | 1.217 | 0.15 |
| 337_F | 518_V | 1.216 | 0.15 |
| 81_R | 943_Y | 1.214 | 0.15 |
| 519_C | 522_N | 1.214 | 0.15 |
| 267_Y | 686_T | 1.212 | 0.15 |
| 780_S | 784_Y | 1.211 | 0.15 |
| 65_N | 761_C | 1.209 | 0.15 |
| 116_V | 252_F | 1.207 | 0.15 |
| 562_W | 586_T | 1.207 | 0.15 |
| 484_K | 747_K | 1.204 | 0.15 |
| 546_I | 873_S | 1.204 | 0.15 |
| 44_T | 198_I | 1.204 | 0.15 |
| 12_S | 329_T | 1.203 | 0.15 |
| 428_D | 850_E | 1.203 | 0.15 |
| 434_Y | 859_E | 1.202 | 0.14 |
| 453_L | 958_P | 1.199 | 0.14 |
| 873_S | 876_S | 1.199 | 0.14 |
| 188_I | 337_F | 1.197 | 0.14 |
| 161_Y | 529_E | 1.197 | 0.14 |
| 806_K | 849_K | 1.195 | 0.14 |
| 62_Y | 484_K | 1.194 | 0.14 |
| 239_N | 253_A | 1.194 | 0.14 |
| 93_G | 788_H | 1.192 | 0.14 |
| 507_F | 553_K | 1.192 | 0.14 |
| 426_V | 627_L | 1.192 | 0.14 |
| 266_L | 942_I | 1.190 | 0.14 |
| 454_V | 873_S | 1.189 | 0.14 |
| 158_L | 943_Y | 1.187 | 0.14 |
| 66_H | 453_L | 1.187 | 0.14 |
| 596_K | 814_K | 1.187 | 0.14 |
| 479_D | 541_L | 1.184 | 0.14 |
| 3_P | 546_I | 1.184 | 0.14 |
| 889_Y | 893_T | 1.184 | 0.14 |
| 206_A | 494_K | 1.183 | 0.14 |
| 489_I | 958_P | 1.183 | 0.14 |
| 846_P | 858_G | 1.182 | 0.14 |
| 568_I | 796_K | 1.182 | 0.14 |
| 529_E | 696_L | 1.180 | 0.14 |
| 194_K | 454_V | 1.179 | 0.14 |
| 228_C | 868_E | 1.179 | 0.14 |
| 210_V | 910_G | 1.179 | 0.14 |
| 98_Y | 211_S | 1.179 | 0.14 |
| 466_N | 519_C | 1.178 | 0.14 |
| 460_C | 929_N | 1.178 | 0.14 |
| 424_L | 942_I | 1.177 | 0.14 |
| 780_S | 859_E | 1.177 | 0.14 |
| 253_A | 710_C | 1.175 | 0.14 |
| 137_N | 413_D | 1.175 | 0.14 |
| 668_N | 772_I | 1.174 | 0.14 |
| 281_L | 573_N | 1.173 | 0.14 |
| 577_A | 750_Q | 1.172 | 0.14 |
| 272_S | 963_L | 1.172 | 0.14 |
| 329_T | 426_V | 1.170 | 0.14 |
| 482_L | 846_P | 1.169 | 0.14 |
| 72_E | 267_Y | 1.169 | 0.14 |
| 211_S | 582_S | 1.169 | 0.14 |
| 52_A | 798_L | 1.168 | 0.14 |
| 644_A | 800_Y | 1.167 | 0.14 |
| 439_F | 585_T | 1.165 | 0.14 |
| 37_A | 205_E | 1.164 | 0.13 |
| 88_R | 283_F | 1.164 | 0.13 |
| 283_F | 505_M | 1.164 | 0.13 |
| 267_Y | 569_E | 1.163 | 0.13 |
| 340_T | 472_F | 1.162 | 0.13 |
| 140_I | 213_I | 1.157 | 0.13 |
| 251_D | 873_S | 1.155 | 0.13 |
| 320_D | 468_L | 1.155 | 0.13 |
| 90_Y | 477_S | 1.154 | 0.13 |
| 823_T | 859_E | 1.154 | 0.13 |
| 501_L | 590_I | 1.154 | 0.13 |
| 588_W | 689_E | 1.154 | 0.13 |
| 167_I | 198_I | 1.152 | 0.13 |
| 84_F | 663_N | 1.152 | 0.13 |
| 439_F | 914_Q | 1.152 | 0.13 |
| 384_I | 469_V | 1.150 | 0.13 |
| 96_R | 413_D | 1.148 | 0.13 |
| 29_V | 180_S | 1.146 | 0.13 |
| 432_R | 548_I | 1.146 | 0.13 |
| 454_V | 934_R | 1.145 | 0.13 |
| 71_D | 585_T | 1.145 | 0.13 |
| 495_L | 659_L | 1.145 | 0.13 |
| 148_K | 535_N | 1.144 | 0.13 |
| 24_P | 104_R | 1.144 | 0.13 |
| 751_H | 874_K | 1.144 | 0.13 |
| 189_H | 292_E | 1.143 | 0.13 |
| 267_Y | 350_K | 1.143 | 0.13 |
| 780_S | 874_K | 1.143 | 0.13 |
| 215_G | 579_D | 1.141 | 0.13 |
| 361_V | 909_I | 1.141 | 0.13 |
| 627_L | 645_I | 1.141 | 0.13 |
| 523_I | 826_I | 1.141 | 0.13 |
| 389_L | 437_S | 1.140 | 0.13 |
| 80_Y | 239_N | 1.140 | 0.13 |
| 109_F | 234_P | 1.139 | 0.13 |
| 359_N | 457_Y | 1.139 | 0.13 |
| 470_Q | 481_Y | 1.138 | 0.13 |
| 747_K | 768_N | 1.138 | 0.13 |
| 632_M | 710_C | 1.138 | 0.13 |
| 644_A | 648_D | 1.136 | 0.13 |
| 455_L | 710_C | 1.135 | 0.13 |
| 267_Y | 592_S | 1.133 | 0.13 |
| 516_G | 566_E | 1.130 | 0.13 |
| 482_L | 489_I | 1.129 | 0.13 |
| 577_A | 591_C | 1.129 | 0.13 |
| 521_K | 775_Y | 1.128 | 0.13 |
| 284_A | 591_C | 1.128 | 0.13 |
| 870_L | 941_E | 1.128 | 0.13 |
| 5_L | 627_L | 1.126 | 0.13 |
| 78_V | 554_D | 1.126 | 0.13 |
| 230_E | 685_P | 1.125 | 0.13 |
| 708_E | 711_R | 1.125 | 0.13 |
| 268_V | 350_K | 1.124 | 0.13 |
| 388_D | 427_L | 1.124 | 0.13 |
| 38_S | 142_W | 1.123 | 0.12 |
| 141_Q | 652_L | 1.123 | 0.12 |
| 443_S | 624_L | 1.121 | 0.12 |
| 281_L | 473_V | 1.120 | 0.12 |
| 92_S | 179_G | 1.119 | 0.12 |
| 33_I | 369_T | 1.119 | 0.12 |
| 446_S | 482_L | 1.118 | 0.12 |
| 399_T | 591_C | 1.116 | 0.12 |
| 549_T | 745_I | 1.115 | 0.12 |
| 325_Y | 481_Y | 1.115 | 0.12 |
| 688_F | 725_V | 1.114 | 0.12 |
| 253_A | 435_S | 1.114 | 0.12 |
| 12_S | 486_K | 1.114 | 0.12 |
| 230_E | 568_I | 1.114 | 0.12 |
| 644_A | 812_G | 1.114 | 0.12 |
| 682_D | 942_I | 1.114 | 0.12 |
| 385_R | 432_R | 1.113 | 0.12 |
| 34_C | 256_K | 1.113 | 0.12 |
| 211_S | 641_S | 1.111 | 0.12 |
| 53_L | 963_L | 1.110 | 0.12 |
| 486_K | 585_T | 1.109 | 0.12 |
| 35_I | 317_S | 1.108 | 0.12 |
| 544_P | 562_W | 1.106 | 0.12 |
| 544_P | 586_T | 1.106 | 0.12 |
| 281_L | 815_R | 1.106 | 0.12 |
| 404_F | 483_K | 1.106 | 0.12 |
| 215_G | 516_G | 1.105 | 0.12 |
| 516_G | 579_D | 1.105 | 0.12 |
| 61_W | 353_L | 1.105 | 0.12 |
| 284_A | 399_T | 1.105 | 0.12 |
| 145_G | 894_Y | 1.105 | 0.12 |
| 87_P | 800_Y | 1.104 | 0.12 |
| 215_G | 566_E | 1.103 | 0.12 |
| 566_E | 579_D | 1.103 | 0.12 |
| 33_I | 224_H | 1.103 | 0.12 |
| 88_R | 526_I | 1.103 | 0.12 |
| 136_G | 352_N | 1.101 | 0.12 |
| 90_Y | 97_A | 1.101 | 0.12 |
| 236_V | 603_S | 1.100 | 0.12 |
| 494_K | 500_Q | 1.100 | 0.12 |
| 328_E | 814_K | 1.100 | 0.12 |
| 592_S | 601_L | 1.100 | 0.12 |
| 268_V | 585_T | 1.099 | 0.12 |
| 815_R | 846_P | 1.098 | 0.12 |
| 519_C | 816_Y | 1.098 | 0.12 |
| 191_Q | 587_L | 1.098 | 0.12 |
| 57_T | 809_E | 1.098 | 0.12 |
| 267_Y | 557_Q | 1.096 | 0.12 |
| 293_Y | 525_L | 1.096 | 0.12 |
| 82_I | 119_P | 1.096 | 0.12 |
| 617_P | 762_Y | 1.095 | 0.12 |
| 97_A | 311_T | 1.095 | 0.12 |
| 62_Y | 300_K | 1.095 | 0.12 |
| 446_S | 489_I | 1.095 | 0.12 |
| 280_F | 519_C | 1.094 | 0.12 |
| 27_E | 961_R | 1.094 | 0.12 |
| 685_P | 829_E | 1.090 | 0.12 |
| 588_W | 812_G | 1.090 | 0.12 |
| 80_Y | 928_N | 1.089 | 0.12 |
| 230_E | 942_I | 1.087 | 0.12 |
| 636_P | 888_L | 1.087 | 0.12 |
| 823_T | 895_I | 1.087 | 0.12 |
| 61_W | 932_L | 1.086 | 0.12 |
| 439_F | 970_I | 1.086 | 0.12 |
| 132_I | 210_V | 1.086 | 0.12 |
| 175_A | 912_D | 1.085 | 0.12 |
| 486_K | 663_N | 1.085 | 0.12 |
| 157_D | 388_D | 1.085 | 0.12 |
| 248_I | 261_G | 1.085 | 0.12 |
| 433_N | 918_I | 1.084 | 0.12 |
| 872_E | 970_I | 1.084 | 0.12 |
| 172_I | 831_E | 1.084 | 0.12 |
| 262_N | 689_E | 1.082 | 0.12 |
| 244_C | 708_E | 1.081 | 0.12 |
| 295_H | 456_N | 1.081 | 0.12 |
| 62_Y | 188_I | 1.081 | 0.12 |
| 797_L | 867_P | 1.081 | 0.12 |
| 332_S | 814_K | 1.081 | 0.12 |
| 645_I | 756_K | 1.080 | 0.12 |
| 110_Y | 158_L | 1.080 | 0.12 |
| 197_E | 561_P | 1.080 | 0.12 |
| 275_D | 459_V | 1.080 | 0.12 |
| 709_M | 754_I | 1.080 | 0.12 |
| 582_S | 787_K | 1.079 | 0.11 |
| 182_E | 230_E | 1.077 | 0.11 |
| 585_T | 832_N | 1.077 | 0.11 |
| 419_E | 783_D | 1.077 | 0.11 |
| 476_G | 926_L | 1.076 | 0.11 |
| 375_H | 472_F | 1.076 | 0.11 |
| 104_R | 766_R | 1.076 | 0.11 |
| 454_V | 908_M | 1.075 | 0.11 |
| 213_I | 740_E | 1.075 | 0.11 |
| 71_D | 962_D | 1.075 | 0.11 |
| 80_Y | 812_G | 1.074 | 0.11 |
| 355_V | 454_V | 1.074 | 0.11 |
| 381_F | 624_L | 1.074 | 0.11 |
| 186_V | 540_K | 1.074 | 0.11 |
| 448_L | 740_E | 1.074 | 0.11 |
| 402_K | 484_K | 1.071 | 0.11 |
| 88_R | 564_P | 1.071 | 0.11 |
| 401_T | 541_L | 1.070 | 0.11 |
| 758_K | 772_I | 1.070 | 0.11 |
| 506_H | 696_L | 1.070 | 0.11 |
| 706_S | 869_S | 1.069 | 0.11 |
| 306_Y | 743_I | 1.069 | 0.11 |
| 14_G | 180_S | 1.069 | 0.11 |
| 701_K | 706_S | 1.069 | 0.11 |
| 826_I | 892_F | 1.069 | 0.11 |
| 35_I | 71_D | 1.069 | 0.11 |
| 267_Y | 942_I | 1.067 | 0.11 |
| 504_A | 781_L | 1.067 | 0.11 |
| 448_L | 775_Y | 1.066 | 0.11 |
| 162_C | 534_G | 1.065 | 0.11 |
| 480_T | 769_L | 1.064 | 0.11 |
| 62_Y | 319_K | 1.064 | 0.11 |
| 870_L | 893_T | 1.064 | 0.11 |
| 270_R | 439_F | 1.062 | 0.11 |
| 98_Y | 489_I | 1.061 | 0.11 |
| 71_D | 664_D | 1.061 | 0.11 |
| 572_K | 850_E | 1.060 | 0.11 |
| 171_S | 826_I | 1.060 | 0.11 |
| 153_L | 413_D | 1.060 | 0.11 |
| 180_S | 675_G | 1.059 | 0.11 |
| 282_T | 347_P | 1.059 | 0.11 |
| 275_D | 685_P | 1.059 | 0.11 |
| 644_A | 855_K | 1.057 | 0.11 |
| 457_Y | 474_K | 1.057 | 0.11 |
| 93_G | 103_S | 1.056 | 0.11 |
| 758_K | 780_S | 1.056 | 0.11 |
| 489_I | 764_A | 1.056 | 0.11 |
| 259_K | 456_N | 1.055 | 0.11 |
| 442_A | 745_I | 1.055 | 0.11 |
| 190_K | 419_E | 1.051 | 0.11 |
| 424_L | 584_G | 1.051 | 0.11 |
| 329_T | 908_M | 1.051 | 0.11 |
| 460_C | 585_T | 1.050 | 0.11 |
| 518_V | 791_R | 1.050 | 0.11 |
| 381_F | 443_S | 1.049 | 0.11 |
| 951_N | 956_Q | 1.049 | 0.11 |
| 389_L | 514_I | 1.049 | 0.11 |
| 227_L | 399_T | 1.047 | 0.11 |
| 453_L | 846_P | 1.047 | 0.11 |
| 535_N | 831_E | 1.047 | 0.11 |
| 354_L | 909_I | 1.047 | 0.11 |
| 328_E | 842_T | 1.046 | 0.11 |
| 643_R | 863_F | 1.046 | 0.11 |
| 210_V | 801_T | 1.046 | 0.11 |
| 90_Y | 295_H | 1.046 | 0.11 |
| 649_L | 855_K | 1.046 | 0.11 |
| 632_M | 708_E | 1.045 | 0.11 |
| 284_A | 297_L | 1.045 | 0.11 |
| 501_L | 540_K | 1.045 | 0.11 |
| 723_V | 912_D | 1.045 | 0.11 |
| 424_L | 682_D | 1.045 | 0.11 |
| 597_P | 623_E | 1.045 | 0.11 |
| 603_S | 842_T | 1.045 | 0.11 |
| 178_E | 778_Y | 1.044 | 0.11 |
| 161_Y | 564_P | 1.044 | 0.11 |
| 337_F | 465_E | 1.042 | 0.11 |
| 363_D | 812_G | 1.042 | 0.11 |
| 322_L | 797_L | 1.042 | 0.11 |
| 26_G | 205_E | 1.041 | 0.11 |
| 354_L | 751_H | 1.041 | 0.11 |
| 330_V | 535_N | 1.041 | 0.11 |
| 64_P | 583_F | 1.041 | 0.11 |
| 97_A | 698_Q | 1.041 | 0.11 |
| 14_G | 176_N | 1.040 | 0.11 |
| 221_A | 599_S | 1.040 | 0.11 |
| 221_A | 730_H | 1.040 | 0.11 |
| 548_I | 911_N | 1.040 | 0.11 |
| 29_V | 288_E | 1.038 | 0.11 |
| 206_A | 606_K | 1.038 | 0.11 |
| 268_V | 548_I | 1.038 | 0.11 |
| 257_L | 933_P | 1.038 | 0.11 |
| 487_N | 842_T | 1.038 | 0.11 |
| 286_E | 663_N | 1.037 | 0.11 |
| 521_K | 772_I | 1.037 | 0.11 |
| 213_I | 468_L | 1.037 | 0.11 |
| 180_S | 532_K | 1.037 | 0.11 |
| 210_V | 362_S | 1.037 | 0.11 |
| 84_F | 929_N | 1.037 | 0.11 |
| 418_H | 887_V | 1.036 | 0.11 |
| 232_A | 560_I | 1.036 | 0.11 |
| 33_I | 223_A | 1.036 | 0.11 |
| 233_P | 699_L | 1.036 | 0.11 |
| 642_F | 837_G | 1.036 | 0.11 |
| 490_N | 578_T | 1.036 | 0.11 |
| 588_W | 867_P | 1.036 | 0.11 |
| 792_I | 842_T | 1.035 | 0.11 |
| 268_V | 600_A | 1.035 | 0.11 |
| 84_F | 424_L | 1.035 | 0.11 |
| 47_Y | 859_E | 1.035 | 0.11 |
| 14_G | 181_N | 1.033 | 0.11 |
| 619_P | 745_I | 1.033 | 0.11 |
| 236_V | 279_Y | 1.033 | 0.11 |
| 514_I | 578_T | 1.032 | 0.10 |
| 273_P | 495_L | 1.032 | 0.10 |
| 420_T | 507_F | 1.032 | 0.10 |
| 84_F | 942_I | 1.031 | 0.10 |
| 161_Y | 283_F | 1.031 | 0.10 |
| 41_C | 632_M | 1.031 | 0.10 |
| 72_E | 832_N | 1.031 | 0.10 |
| 135_T | 459_V | 1.030 | 0.10 |
| 268_V | 570_N | 1.030 | 0.10 |
| 349_D | 554_D | 1.030 | 0.10 |
| 525_L | 752_D | 1.030 | 0.10 |
| 884_F | 901_P | 1.030 | 0.10 |
| 131_T | 967_V | 1.028 | 0.10 |
| 522_N | 780_S | 1.028 | 0.10 |
| 652_L | 783_D | 1.028 | 0.10 |
| 296_C | 563_V | 1.028 | 0.10 |
| 459_V | 514_I | 1.027 | 0.10 |
| 9_L | 357_R | 1.026 | 0.10 |
| 190_K | 223_A | 1.025 | 0.10 |
| 465_E | 745_I | 1.025 | 0.10 |
| 549_T | 644_A | 1.025 | 0.10 |
| 200_L | 738_D | 1.025 | 0.10 |
| 90_Y | 751_H | 1.025 | 0.10 |
| 256_K | 645_I | 1.025 | 0.10 |
| 308_L | 688_F | 1.025 | 0.10 |
| 311_T | 591_C | 1.025 | 0.10 |
| 496_E | 735_H | 1.023 | 0.10 |
| 188_I | 638_F | 1.022 | 0.10 |
| 276_F | 738_D | 1.022 | 0.10 |
| 294_K | 546_I | 1.022 | 0.10 |
| 432_R | 688_F | 1.022 | 0.10 |
| 557_Q | 831_E | 1.021 | 0.10 |
| 103_S | 183_S | 1.021 | 0.10 |
| 330_V | 339_F | 1.021 | 0.10 |
| 768_N | 823_T | 1.021 | 0.10 |
| 172_I | 683_R | 1.021 | 0.10 |
| 929_N | 944_M | 1.021 | 0.10 |
| 519_C | 872_E | 1.020 | 0.10 |
| 509_E | 946_M | 1.020 | 0.10 |
| 585_T | 732_T | 1.020 | 0.10 |
| 631_C | 771_L | 1.018 | 0.10 |
| 162_C | 617_P | 1.018 | 0.10 |
| 322_L | 741_R | 1.017 | 0.10 |
| 30_A | 494_K | 1.017 | 0.10 |
| 511_N | 584_G | 1.017 | 0.10 |
| 280_F | 970_I | 1.016 | 0.10 |
| 459_V | 723_V | 1.016 | 0.10 |
| 85_Y | 963_L | 1.016 | 0.10 |
| 472_F | 959_S | 1.016 | 0.10 |
| 495_L | 701_K | 1.016 | 0.10 |
| 272_S | 479_D | 1.016 | 0.10 |
| 812_G | 904_E | 1.016 | 0.10 |
| 345_P | 566_E | 1.016 | 0.10 |
| 248_I | 867_P | 1.015 | 0.10 |
| 301_N | 602_D | 1.015 | 0.10 |
| 276_F | 731_S | 1.013 | 0.10 |
| 270_R | 745_I | 1.013 | 0.10 |
| 109_F | 341_K | 1.013 | 0.10 |
| 783_D | 829_E | 1.012 | 0.10 |
| 114_F | 582_S | 1.012 | 0.10 |
| 550_V | 954_V | 1.012 | 0.10 |
| 163_D | 719_T | 1.012 | 0.10 |
| 256_K | 881_V | 1.011 | 0.10 |
| 575_N | 648_D | 1.011 | 0.10 |
| 176_N | 181_N | 1.011 | 0.10 |
| 315_F | 858_G | 1.011 | 0.10 |
| 513_L | 591_C | 1.011 | 0.10 |
| 468_L | 954_V | 1.011 | 0.10 |
| 577_A | 751_H | 1.010 | 0.10 |
| 266_L | 817_I | 1.010 | 0.10 |
| 459_V | 597_P | 1.010 | 0.10 |
| 448_L | 513_L | 1.008 | 0.10 |
| 814_K | 954_V | 1.008 | 0.10 |
| 566_E | 647_R | 1.008 | 0.10 |
| 276_F | 572_K | 1.007 | 0.10 |
| 375_H | 411_V | 1.007 | 0.10 |
| 689_E | 831_E | 1.007 | 0.10 |
| 132_I | 217_Y | 1.007 | 0.10 |
| 360_G | 909_I | 1.007 | 0.10 |
| 105_G | 591_C | 1.006 | 0.10 |
| 269_L | 318_L | 1.006 | 0.10 |
| 385_R | 547_S | 1.006 | 0.10 |
| 753_N | 780_S | 1.006 | 0.10 |
| 704_F | 843_K | 1.006 | 0.10 |
| 100_H | 475_F | 1.005 | 0.10 |
| 110_Y | 456_N | 1.005 | 0.10 |
| 71_D | 375_H | 1.005 | 0.10 |
| 80_Y | 196_L | 1.005 | 0.10 |
| 426_V | 968_D | 1.005 | 0.10 |
| 748_S | 776_L | 1.003 | 0.10 |
| 236_V | 842_T | 1.003 | 0.10 |
| 713_D | 720_G | 1.003 | 0.10 |
| 448_L | 454_V | 1.003 | 0.10 |
| 575_N | 929_N | 1.003 | 0.10 |
| 80_Y | 165_P | 1.003 | 0.10 |
| 149_E | 413_D | 1.002 | 0.10 |
| 599_S | 909_I | 1.002 | 0.10 |
| 337_F | 412_G | 1.002 | 0.10 |
| 200_L | 797_L | 1.001 | 0.10 |
| 519_C | 780_S | 1.001 | 0.10 |
| 89_W | 713_D | 1.001 | 0.10 |
| 588_W | 632_M | 1.001 | 0.10 |
| 97_A | 477_S | 1.000 | 0.10 |
| 185_V | 548_I | 1.000 | 0.10 |
| 78_V | 604_Q | 1.000 | 0.10 |
| 7_V | 210_V | 1.000 | 0.10 |
| 253_A | 455_L | 1.000 | 0.10 |
| 936_D | 942_I | 1.000 | 0.10 |
| 522_N | 902_P | 1.000 | 0.10 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 4oliA | 1 | 0.5528 | 100 | 0.715 | Contact Map |
| 4po6A | 1 | 0.3385 | 100 | 0.814 | Contact Map |
| 4fl3A | 1 | 0.5262 | 100 | 0.834 | Contact Map |
| 4e5wA | 2 | 0.3005 | 100 | 0.842 | Contact Map |
| 2ozoA | 1 | 0.5323 | 100 | 0.844 | Contact Map |
| 3ugcA | 1 | 0.281 | 100 | 0.855 | Contact Map |
| 4rt7A | 1 | 0 | 100 | 0.857 | Contact Map |
| 2w1iA | 2 | 0.2903 | 100 | 0.857 | Contact Map |
| 3lxpA | 1 | 0.2903 | 100 | 0.86 | Contact Map |
| 1qcfA | 1 | 0.4492 | 100 | 0.862 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)