| BubR1 -force run |
| ID: | 1408008917 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 1050 (1024) | ||
| Sequences: | 135 (96.9) | ||
| Seq/Len: | 0.132 | ||
| Nf(neff/√len): | 3.0 |
HHblits Results: (2013_03)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 0.132).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 883_L | 959_L | 2.723 | 0.82 |
| 139_Y | 998_V | 1.999 | 0.49 |
| 815_L | 843_T | 1.849 | 0.41 |
| 884_S | 913_S | 1.806 | 0.38 |
| 163_E | 199_R | 1.793 | 0.38 |
| 196_F | 199_R | 1.764 | 0.36 |
| 886_R | 913_S | 1.750 | 0.36 |
| 310_A | 848_L | 1.740 | 0.35 |
| 27_E | 36_R | 1.687 | 0.32 |
| 619_S | 622_F | 1.682 | 0.32 |
| 1034_A | 1040_K | 1.623 | 0.30 |
| 27_E | 41_L | 1.596 | 0.28 |
| 158_W | 841_C | 1.592 | 0.28 |
| 91_Q | 96_S | 1.589 | 0.28 |
| 815_L | 959_L | 1.585 | 0.28 |
| 36_R | 41_L | 1.583 | 0.28 |
| 412_F | 858_I | 1.554 | 0.27 |
| 109_L | 967_E | 1.546 | 0.26 |
| 27_E | 32_L | 1.540 | 0.26 |
| 142_L | 870_V | 1.537 | 0.26 |
| 32_L | 36_R | 1.527 | 0.25 |
| 183_A | 867_L | 1.526 | 0.25 |
| 27_E | 35_G | 1.524 | 0.25 |
| 174_I | 959_L | 1.520 | 0.25 |
| 793_V | 987_L | 1.513 | 0.25 |
| 197_Q | 416_R | 1.507 | 0.25 |
| 65_E | 80_R | 1.495 | 0.24 |
| 271_R | 302_R | 1.494 | 0.24 |
| 148_G | 171_A | 1.494 | 0.24 |
| 403_I | 980_L | 1.478 | 0.23 |
| 844_L | 862_I | 1.475 | 0.23 |
| 36_R | 306_N | 1.465 | 0.23 |
| 669_L | 762_G | 1.462 | 0.23 |
| 892_N | 905_Q | 1.462 | 0.23 |
| 882_D | 913_S | 1.459 | 0.23 |
| 125_W | 151_L | 1.455 | 0.23 |
| 171_A | 958_D | 1.454 | 0.23 |
| 27_E | 306_N | 1.452 | 0.22 |
| 454_K | 691_S | 1.449 | 0.22 |
| 35_G | 41_L | 1.445 | 0.22 |
| 416_R | 950_Q | 1.439 | 0.22 |
| 27_E | 96_S | 1.434 | 0.22 |
| 40_T | 949_Y | 1.429 | 0.22 |
| 36_R | 96_S | 1.426 | 0.22 |
| 32_L | 35_G | 1.422 | 0.21 |
| 84_W | 189_L | 1.421 | 0.21 |
| 845_Q | 913_S | 1.419 | 0.21 |
| 807_I | 979_K | 1.416 | 0.21 |
| 791_L | 830_D | 1.409 | 0.21 |
| 734_L | 806_Y | 1.403 | 0.21 |
| 275_F | 302_R | 1.398 | 0.20 |
| 162_Y | 881_G | 1.398 | 0.20 |
| 270_S | 963_L | 1.396 | 0.20 |
| 129_G | 152_A | 1.395 | 0.20 |
| 82_I | 170_K | 1.393 | 0.20 |
| 991_E | 1018_E | 1.393 | 0.20 |
| 23_E | 394_E | 1.390 | 0.20 |
| 271_R | 277_E | 1.386 | 0.20 |
| 126_L | 222_P | 1.383 | 0.20 |
| 970_Q | 985_S | 1.383 | 0.20 |
| 32_L | 41_L | 1.379 | 0.20 |
| 96_S | 304_K | 1.376 | 0.20 |
| 400_K | 978_W | 1.376 | 0.20 |
| 122_L | 151_L | 1.375 | 0.20 |
| 187_E | 416_R | 1.372 | 0.20 |
| 927_L | 959_L | 1.370 | 0.20 |
| 41_L | 306_N | 1.370 | 0.20 |
| 797_S | 914_Y | 1.366 | 0.19 |
| 66_I | 406_G | 1.366 | 0.19 |
| 670_S | 674_E | 1.366 | 0.19 |
| 151_L | 188_R | 1.365 | 0.19 |
| 135_P | 873_L | 1.362 | 0.19 |
| 96_S | 306_N | 1.359 | 0.19 |
| 275_F | 306_N | 1.356 | 0.19 |
| 845_Q | 884_S | 1.347 | 0.19 |
| 841_C | 890_L | 1.346 | 0.19 |
| 777_D | 782_W | 1.343 | 0.19 |
| 845_Q | 1000_I | 1.340 | 0.19 |
| 80_R | 105_A | 1.337 | 0.18 |
| 831_G | 988_K | 1.334 | 0.18 |
| 889_I | 980_L | 1.333 | 0.18 |
| 275_F | 305_E | 1.333 | 0.18 |
| 91_Q | 280_D | 1.331 | 0.18 |
| 226_T | 274_V | 1.327 | 0.18 |
| 122_L | 881_G | 1.324 | 0.18 |
| 65_E | 105_A | 1.320 | 0.18 |
| 671_P | 768_I | 1.319 | 0.18 |
| 66_I | 890_L | 1.317 | 0.18 |
| 36_R | 305_E | 1.317 | 0.18 |
| 882_D | 886_R | 1.313 | 0.18 |
| 27_E | 305_E | 1.308 | 0.18 |
| 23_E | 151_L | 1.306 | 0.17 |
| 66_I | 841_C | 1.304 | 0.17 |
| 867_L | 871_E | 1.304 | 0.17 |
| 106_V | 830_D | 1.303 | 0.17 |
| 125_W | 846_D | 1.303 | 0.17 |
| 26_K | 35_G | 1.301 | 0.17 |
| 779_K | 883_L | 1.300 | 0.17 |
| 963_L | 974_D | 1.300 | 0.17 |
| 26_K | 36_R | 1.300 | 0.17 |
| 125_W | 856_H | 1.298 | 0.17 |
| 913_S | 968_H | 1.297 | 0.17 |
| 122_L | 866_L | 1.297 | 0.17 |
| 35_G | 306_N | 1.293 | 0.17 |
| 884_S | 966_K | 1.293 | 0.17 |
| 32_L | 306_N | 1.293 | 0.17 |
| 241_P | 800_P | 1.290 | 0.17 |
| 151_L | 846_D | 1.287 | 0.17 |
| 674_E | 678_E | 1.287 | 0.17 |
| 916_V | 1010_S | 1.287 | 0.17 |
| 840_N | 949_Y | 1.287 | 0.17 |
| 35_G | 96_S | 1.287 | 0.17 |
| 172_D | 176_Q | 1.285 | 0.17 |
| 841_C | 892_N | 1.284 | 0.17 |
| 176_Q | 180_Q | 1.281 | 0.17 |
| 27_E | 304_K | 1.281 | 0.17 |
| 86_E | 127_K | 1.278 | 0.17 |
| 41_L | 96_S | 1.278 | 0.17 |
| 841_C | 905_Q | 1.275 | 0.17 |
| 672_I | 730_L | 1.275 | 0.17 |
| 32_L | 137_D | 1.267 | 0.16 |
| 311_G | 317_R | 1.265 | 0.16 |
| 59_K | 144_N | 1.264 | 0.16 |
| 838_Y | 891_R | 1.264 | 0.16 |
| 580_E | 806_Y | 1.262 | 0.16 |
| 121_F | 889_I | 1.261 | 0.16 |
| 99_S | 996_F | 1.261 | 0.16 |
| 36_R | 304_K | 1.260 | 0.16 |
| 882_D | 911_D | 1.252 | 0.16 |
| 416_R | 949_Y | 1.252 | 0.16 |
| 834_V | 849_Q | 1.248 | 0.16 |
| 858_I | 1000_I | 1.245 | 0.16 |
| 140_S | 416_R | 1.242 | 0.16 |
| 884_S | 887_C | 1.241 | 0.16 |
| 116_Y | 883_L | 1.241 | 0.16 |
| 845_Q | 986_E | 1.237 | 0.15 |
| 89_Y | 96_S | 1.235 | 0.15 |
| 1010_S | 1016_A | 1.235 | 0.15 |
| 35_G | 305_E | 1.234 | 0.15 |
| 877_E | 925_F | 1.231 | 0.15 |
| 883_L | 907_L | 1.231 | 0.15 |
| 151_L | 727_R | 1.229 | 0.15 |
| 104_R | 985_S | 1.225 | 0.15 |
| 1033_K | 1037_K | 1.225 | 0.15 |
| 907_L | 959_L | 1.224 | 0.15 |
| 774_I | 963_L | 1.222 | 0.15 |
| 413_E | 731_L | 1.222 | 0.15 |
| 753_L | 801_V | 1.222 | 0.15 |
| 23_E | 302_R | 1.222 | 0.15 |
| 466_D | 953_L | 1.221 | 0.15 |
| 135_P | 163_E | 1.219 | 0.15 |
| 122_L | 188_R | 1.219 | 0.15 |
| 995_K | 1018_E | 1.219 | 0.15 |
| 793_V | 865_N | 1.219 | 0.15 |
| 884_S | 968_H | 1.218 | 0.15 |
| 82_I | 410_F | 1.215 | 0.15 |
| 488_K | 516_Q | 1.215 | 0.15 |
| 674_E | 878_I | 1.215 | 0.15 |
| 275_F | 866_L | 1.215 | 0.15 |
| 95_E | 586_P | 1.211 | 0.15 |
| 339_S | 343_Y | 1.211 | 0.15 |
| 163_E | 196_F | 1.209 | 0.15 |
| 158_W | 905_Q | 1.208 | 0.15 |
| 524_P | 531_F | 1.208 | 0.15 |
| 166_E | 869_I | 1.205 | 0.15 |
| 26_K | 41_L | 1.204 | 0.14 |
| 631_L | 772_Y | 1.204 | 0.14 |
| 25_S | 867_L | 1.204 | 0.14 |
| 80_R | 135_P | 1.204 | 0.14 |
| 96_S | 275_F | 1.202 | 0.14 |
| 41_L | 305_E | 1.201 | 0.14 |
| 151_L | 394_E | 1.201 | 0.14 |
| 126_L | 496_S | 1.201 | 0.14 |
| 148_G | 189_L | 1.199 | 0.14 |
| 884_S | 987_L | 1.199 | 0.14 |
| 21_E | 45_L | 1.199 | 0.14 |
| 59_K | 78_W | 1.198 | 0.14 |
| 797_S | 985_S | 1.198 | 0.14 |
| 36_R | 275_F | 1.198 | 0.14 |
| 96_S | 305_E | 1.196 | 0.14 |
| 802_P | 870_V | 1.195 | 0.14 |
| 188_R | 866_L | 1.195 | 0.14 |
| 700_C | 896_D | 1.195 | 0.14 |
| 178_G | 881_G | 1.195 | 0.14 |
| 28_N | 36_R | 1.193 | 0.14 |
| 85_T | 757_K | 1.192 | 0.14 |
| 961_H | 1011_V | 1.191 | 0.14 |
| 38_M | 930_F | 1.191 | 0.14 |
| 117_S | 188_R | 1.189 | 0.14 |
| 178_G | 1003_A | 1.188 | 0.14 |
| 192_Q | 195_Q | 1.188 | 0.14 |
| 41_L | 304_K | 1.188 | 0.14 |
| 913_S | 966_K | 1.188 | 0.14 |
| 128_L | 838_Y | 1.188 | 0.14 |
| 119_P | 154_F | 1.188 | 0.14 |
| 95_E | 791_L | 1.186 | 0.14 |
| 349_R | 956_I | 1.185 | 0.14 |
| 280_D | 983_N | 1.185 | 0.14 |
| 886_R | 966_K | 1.185 | 0.14 |
| 27_E | 275_F | 1.183 | 0.14 |
| 832_C | 883_L | 1.183 | 0.14 |
| 26_K | 32_L | 1.183 | 0.14 |
| 855_T | 984_I | 1.183 | 0.14 |
| 72_N | 713_T | 1.182 | 0.14 |
| 734_L | 907_L | 1.179 | 0.14 |
| 28_N | 32_L | 1.178 | 0.14 |
| 32_L | 96_S | 1.178 | 0.14 |
| 29_V | 307_E | 1.172 | 0.14 |
| 92_G | 137_D | 1.172 | 0.14 |
| 833_I | 905_Q | 1.172 | 0.14 |
| 195_Q | 294_P | 1.170 | 0.14 |
| 66_I | 783_V | 1.170 | 0.14 |
| 910_V | 913_S | 1.169 | 0.14 |
| 797_S | 891_R | 1.169 | 0.14 |
| 632_P | 881_G | 1.169 | 0.14 |
| 275_F | 304_K | 1.168 | 0.14 |
| 95_E | 979_K | 1.168 | 0.14 |
| 913_S | 985_S | 1.166 | 0.14 |
| 618_V | 621_P | 1.166 | 0.14 |
| 946_S | 954_F | 1.165 | 0.13 |
| 26_K | 305_E | 1.165 | 0.13 |
| 886_R | 968_H | 1.165 | 0.13 |
| 76_D | 80_R | 1.163 | 0.13 |
| 71_G | 86_E | 1.163 | 0.13 |
| 963_L | 984_I | 1.163 | 0.13 |
| 392_K | 704_P | 1.163 | 0.13 |
| 59_K | 136_L | 1.163 | 0.13 |
| 801_V | 877_E | 1.162 | 0.13 |
| 28_N | 304_K | 1.162 | 0.13 |
| 224_R | 227_L | 1.158 | 0.13 |
| 310_A | 654_T | 1.158 | 0.13 |
| 24_L | 31_P | 1.158 | 0.13 |
| 142_L | 159_A | 1.158 | 0.13 |
| 720_S | 881_G | 1.158 | 0.13 |
| 966_K | 1010_S | 1.156 | 0.13 |
| 43_G | 54_T | 1.156 | 0.13 |
| 178_G | 740_S | 1.155 | 0.13 |
| 32_L | 91_Q | 1.155 | 0.13 |
| 871_E | 1016_A | 1.155 | 0.13 |
| 848_L | 1003_A | 1.155 | 0.13 |
| 69_Y | 398_Y | 1.153 | 0.13 |
| 32_L | 305_E | 1.153 | 0.13 |
| 352_V | 359_E | 1.153 | 0.13 |
| 30_Q | 38_M | 1.152 | 0.13 |
| 121_F | 157_S | 1.150 | 0.13 |
| 37_I | 797_S | 1.149 | 0.13 |
| 87_Q | 193_H | 1.149 | 0.13 |
| 412_F | 805_F | 1.149 | 0.13 |
| 32_L | 304_K | 1.147 | 0.13 |
| 187_E | 197_Q | 1.147 | 0.13 |
| 521_S | 756_E | 1.146 | 0.13 |
| 78_W | 114_R | 1.145 | 0.13 |
| 838_Y | 843_T | 1.145 | 0.13 |
| 98_M | 133_N | 1.143 | 0.13 |
| 69_Y | 86_E | 1.142 | 0.13 |
| 31_P | 34_Q | 1.140 | 0.13 |
| 150_S | 815_L | 1.140 | 0.13 |
| 101_L | 135_P | 1.140 | 0.13 |
| 888_L | 988_K | 1.140 | 0.13 |
| 121_F | 175_F | 1.140 | 0.13 |
| 838_Y | 961_H | 1.139 | 0.13 |
| 66_I | 158_W | 1.139 | 0.13 |
| 416_R | 794_I | 1.137 | 0.13 |
| 1016_A | 1020_N | 1.136 | 0.13 |
| 158_W | 949_Y | 1.136 | 0.13 |
| 76_D | 163_E | 1.134 | 0.13 |
| 156_I | 188_R | 1.134 | 0.13 |
| 845_Q | 858_I | 1.134 | 0.13 |
| 156_I | 988_K | 1.134 | 0.13 |
| 28_N | 41_L | 1.133 | 0.13 |
| 862_I | 918_L | 1.133 | 0.13 |
| 225_S | 229_E | 1.132 | 0.13 |
| 913_S | 987_L | 1.132 | 0.13 |
| 84_W | 89_Y | 1.132 | 0.13 |
| 848_L | 858_I | 1.132 | 0.13 |
| 448_E | 781_F | 1.130 | 0.13 |
| 410_F | 708_E | 1.130 | 0.13 |
| 884_S | 910_V | 1.129 | 0.13 |
| 298_P | 910_V | 1.127 | 0.13 |
| 22_W | 274_V | 1.127 | 0.13 |
| 884_S | 985_S | 1.127 | 0.13 |
| 144_N | 184_E | 1.127 | 0.13 |
| 102_L | 142_L | 1.126 | 0.13 |
| 141_Y | 272_I | 1.126 | 0.13 |
| 731_L | 885_P | 1.126 | 0.13 |
| 62_F | 743_L | 1.126 | 0.13 |
| 102_L | 163_E | 1.124 | 0.12 |
| 934_Q | 963_L | 1.124 | 0.12 |
| 941_I | 945_C | 1.123 | 0.12 |
| 146_G | 778_Y | 1.123 | 0.12 |
| 97_N | 979_K | 1.123 | 0.12 |
| 139_Y | 801_V | 1.123 | 0.12 |
| 891_R | 914_Y | 1.122 | 0.12 |
| 121_F | 192_Q | 1.122 | 0.12 |
| 43_G | 53_N | 1.119 | 0.12 |
| 22_W | 29_V | 1.117 | 0.12 |
| 804_D | 887_C | 1.117 | 0.12 |
| 810_K | 920_V | 1.116 | 0.12 |
| 86_E | 158_W | 1.116 | 0.12 |
| 23_E | 26_K | 1.116 | 0.12 |
| 23_E | 35_G | 1.116 | 0.12 |
| 884_S | 986_E | 1.114 | 0.12 |
| 914_Y | 985_S | 1.114 | 0.12 |
| 126_L | 410_F | 1.113 | 0.12 |
| 126_L | 359_E | 1.113 | 0.12 |
| 800_P | 832_C | 1.113 | 0.12 |
| 62_F | 990_G | 1.111 | 0.12 |
| 544_P | 863_I | 1.111 | 0.12 |
| 608_T | 611_F | 1.111 | 0.12 |
| 67_R | 1014_E | 1.111 | 0.12 |
| 932_T | 969_L | 1.110 | 0.12 |
| 837_Q | 949_Y | 1.110 | 0.12 |
| 150_S | 878_I | 1.109 | 0.12 |
| 15_M | 1011_V | 1.109 | 0.12 |
| 842_F | 916_V | 1.106 | 0.12 |
| 834_V | 986_E | 1.106 | 0.12 |
| 99_S | 114_R | 1.106 | 0.12 |
| 544_P | 568_T | 1.106 | 0.12 |
| 28_N | 96_S | 1.104 | 0.12 |
| 84_W | 102_L | 1.104 | 0.12 |
| 22_W | 38_M | 1.104 | 0.12 |
| 875_K | 903_N | 1.104 | 0.12 |
| 622_F | 762_G | 1.103 | 0.12 |
| 843_T | 979_K | 1.103 | 0.12 |
| 847_L | 977_F | 1.103 | 0.12 |
| 887_C | 913_S | 1.101 | 0.12 |
| 197_Q | 978_W | 1.101 | 0.12 |
| 845_Q | 887_C | 1.101 | 0.12 |
| 727_R | 866_L | 1.101 | 0.12 |
| 797_S | 969_L | 1.101 | 0.12 |
| 605_P | 619_S | 1.100 | 0.12 |
| 884_S | 914_Y | 1.100 | 0.12 |
| 806_Y | 954_F | 1.100 | 0.12 |
| 81_Y | 147_I | 1.100 | 0.12 |
| 404_Y | 912_F | 1.100 | 0.12 |
| 464_T | 994_N | 1.099 | 0.12 |
| 84_W | 96_S | 1.099 | 0.12 |
| 228_A | 241_P | 1.099 | 0.12 |
| 420_F | 920_V | 1.097 | 0.12 |
| 149_V | 974_D | 1.097 | 0.12 |
| 888_L | 914_Y | 1.097 | 0.12 |
| 24_L | 401_E | 1.093 | 0.12 |
| 142_L | 415_I | 1.091 | 0.12 |
| 91_Q | 275_F | 1.091 | 0.12 |
| 538_E | 734_L | 1.091 | 0.12 |
| 41_L | 91_Q | 1.090 | 0.12 |
| 23_E | 27_E | 1.090 | 0.12 |
| 85_T | 104_R | 1.088 | 0.12 |
| 767_C | 796_V | 1.088 | 0.12 |
| 925_F | 998_V | 1.088 | 0.12 |
| 23_E | 36_R | 1.087 | 0.12 |
| 469_E | 555_R | 1.087 | 0.12 |
| 797_S | 845_Q | 1.087 | 0.12 |
| 797_S | 986_E | 1.086 | 0.12 |
| 806_Y | 870_V | 1.086 | 0.12 |
| 523_G | 527_P | 1.086 | 0.12 |
| 671_P | 676_S | 1.084 | 0.12 |
| 775_C | 797_S | 1.084 | 0.12 |
| 169_R | 193_H | 1.084 | 0.12 |
| 26_K | 306_N | 1.084 | 0.12 |
| 29_V | 36_R | 1.084 | 0.12 |
| 415_I | 450_E | 1.083 | 0.12 |
| 35_G | 304_K | 1.080 | 0.11 |
| 381_R | 806_Y | 1.080 | 0.11 |
| 78_W | 841_C | 1.080 | 0.11 |
| 768_I | 794_I | 1.080 | 0.11 |
| 114_R | 841_C | 1.080 | 0.11 |
| 887_C | 910_V | 1.080 | 0.11 |
| 121_F | 856_H | 1.078 | 0.11 |
| 797_S | 913_S | 1.078 | 0.11 |
| 79_D | 737_L | 1.078 | 0.11 |
| 39_S | 726_Y | 1.078 | 0.11 |
| 176_Q | 949_Y | 1.076 | 0.11 |
| 125_W | 188_R | 1.076 | 0.11 |
| 151_L | 773_L | 1.074 | 0.11 |
| 87_Q | 172_D | 1.074 | 0.11 |
| 916_V | 925_F | 1.074 | 0.11 |
| 815_L | 870_V | 1.074 | 0.11 |
| 153_Q | 888_L | 1.073 | 0.11 |
| 35_G | 275_F | 1.071 | 0.11 |
| 547_D | 580_E | 1.071 | 0.11 |
| 119_P | 151_L | 1.071 | 0.11 |
| 275_F | 955_G | 1.070 | 0.11 |
| 106_V | 989_D | 1.070 | 0.11 |
| 797_S | 888_L | 1.070 | 0.11 |
| 671_P | 737_L | 1.068 | 0.11 |
| 31_P | 137_D | 1.068 | 0.11 |
| 960_A | 996_F | 1.068 | 0.11 |
| 886_R | 947_S | 1.068 | 0.11 |
| 394_E | 846_D | 1.067 | 0.11 |
| 533_E | 575_P | 1.065 | 0.11 |
| 531_F | 578_C | 1.064 | 0.11 |
| 399_C | 774_I | 1.063 | 0.11 |
| 886_R | 987_L | 1.063 | 0.11 |
| 80_R | 189_L | 1.063 | 0.11 |
| 605_P | 610_D | 1.061 | 0.11 |
| 228_A | 235_K | 1.061 | 0.11 |
| 674_E | 885_P | 1.061 | 0.11 |
| 865_N | 987_L | 1.061 | 0.11 |
| 80_R | 102_L | 1.060 | 0.11 |
| 76_D | 172_D | 1.060 | 0.11 |
| 683_S | 883_L | 1.060 | 0.11 |
| 39_S | 907_L | 1.060 | 0.11 |
| 96_S | 122_L | 1.058 | 0.11 |
| 831_G | 914_Y | 1.058 | 0.11 |
| 431_E | 680_T | 1.058 | 0.11 |
| 635_P | 945_C | 1.058 | 0.11 |
| 100_T | 187_E | 1.058 | 0.11 |
| 33_R | 318_S | 1.058 | 0.11 |
| 811_L | 824_S | 1.057 | 0.11 |
| 683_S | 743_L | 1.057 | 0.11 |
| 849_Q | 887_C | 1.055 | 0.11 |
| 797_S | 831_G | 1.053 | 0.11 |
| 45_L | 961_H | 1.053 | 0.11 |
| 416_R | 837_Q | 1.053 | 0.11 |
| 170_K | 950_Q | 1.053 | 0.11 |
| 857_E | 876_A | 1.053 | 0.11 |
| 137_D | 277_E | 1.051 | 0.11 |
| 906_A | 985_S | 1.051 | 0.11 |
| 799_Q | 842_F | 1.051 | 0.11 |
| 723_C | 736_E | 1.051 | 0.11 |
| 831_G | 855_T | 1.050 | 0.11 |
| 26_K | 96_S | 1.050 | 0.11 |
| 756_E | 774_I | 1.048 | 0.11 |
| 242_I | 309_Q | 1.048 | 0.11 |
| 308_L | 864_Y | 1.048 | 0.11 |
| 806_Y | 878_I | 1.048 | 0.11 |
| 831_G | 888_L | 1.047 | 0.11 |
| 34_Q | 961_H | 1.047 | 0.11 |
| 886_R | 918_L | 1.047 | 0.11 |
| 44_A | 963_L | 1.047 | 0.11 |
| 806_Y | 907_L | 1.047 | 0.11 |
| 762_G | 981_S | 1.047 | 0.11 |
| 184_E | 831_G | 1.047 | 0.11 |
| 41_L | 275_F | 1.045 | 0.11 |
| 139_Y | 802_P | 1.045 | 0.11 |
| 670_S | 678_E | 1.045 | 0.11 |
| 727_R | 775_C | 1.045 | 0.11 |
| 630_D | 714_S | 1.044 | 0.11 |
| 605_P | 669_L | 1.042 | 0.11 |
| 65_E | 98_M | 1.042 | 0.11 |
| 966_K | 1016_A | 1.042 | 0.11 |
| 89_Y | 178_G | 1.041 | 0.11 |
| 33_R | 312_P | 1.041 | 0.11 |
| 162_Y | 1022_V | 1.041 | 0.11 |
| 85_T | 101_L | 1.040 | 0.11 |
| 27_E | 137_D | 1.038 | 0.11 |
| 723_C | 826_Y | 1.038 | 0.11 |
| 885_P | 962_L | 1.037 | 0.11 |
| 347_T | 970_Q | 1.035 | 0.11 |
| 622_F | 741_A | 1.035 | 0.11 |
| 129_G | 844_L | 1.035 | 0.11 |
| 280_D | 904_N | 1.034 | 0.11 |
| 36_R | 137_D | 1.034 | 0.11 |
| 137_D | 304_K | 1.034 | 0.11 |
| 891_R | 898_Y | 1.034 | 0.11 |
| 807_I | 810_K | 1.034 | 0.11 |
| 403_I | 890_L | 1.032 | 0.10 |
| 523_G | 531_F | 1.032 | 0.10 |
| 151_L | 178_G | 1.032 | 0.10 |
| 589_E | 595_G | 1.032 | 0.10 |
| 127_K | 145_Q | 1.031 | 0.10 |
| 539_K | 612_A | 1.031 | 0.10 |
| 182_K | 293_Q | 1.031 | 0.10 |
| 79_D | 731_L | 1.031 | 0.10 |
| 188_R | 773_L | 1.031 | 0.10 |
| 142_L | 759_I | 1.031 | 0.10 |
| 139_Y | 995_K | 1.028 | 0.10 |
| 887_C | 986_E | 1.028 | 0.10 |
| 29_V | 799_Q | 1.028 | 0.10 |
| 222_P | 547_D | 1.028 | 0.10 |
| 254_Q | 736_E | 1.028 | 0.10 |
| 684_G | 713_T | 1.028 | 0.10 |
| 33_R | 138_M | 1.027 | 0.10 |
| 35_G | 89_Y | 1.027 | 0.10 |
| 797_S | 988_K | 1.027 | 0.10 |
| 26_K | 89_Y | 1.027 | 0.10 |
| 227_L | 295_W | 1.025 | 0.10 |
| 882_D | 968_H | 1.025 | 0.10 |
| 91_Q | 119_P | 1.025 | 0.10 |
| 257_G | 310_A | 1.024 | 0.10 |
| 31_P | 995_K | 1.024 | 0.10 |
| 122_L | 737_L | 1.024 | 0.10 |
| 62_F | 876_A | 1.024 | 0.10 |
| 826_Y | 1038_V | 1.024 | 0.10 |
| 977_F | 999_R | 1.024 | 0.10 |
| 401_E | 975_G | 1.022 | 0.10 |
| 804_D | 910_V | 1.022 | 0.10 |
| 415_I | 837_Q | 1.022 | 0.10 |
| 649_S | 654_T | 1.022 | 0.10 |
| 469_E | 473_P | 1.021 | 0.10 |
| 727_R | 969_L | 1.021 | 0.10 |
| 668_K | 761_L | 1.021 | 0.10 |
| 487_Q | 755_I | 1.019 | 0.10 |
| 739_A | 844_L | 1.019 | 0.10 |
| 914_Y | 988_K | 1.019 | 0.10 |
| 777_D | 794_I | 1.018 | 0.10 |
| 37_I | 914_Y | 1.018 | 0.10 |
| 153_Q | 156_I | 1.018 | 0.10 |
| 88_N | 294_P | 1.018 | 0.10 |
| 271_R | 275_F | 1.017 | 0.10 |
| 187_E | 415_I | 1.017 | 0.10 |
| 178_G | 188_R | 1.017 | 0.10 |
| 310_A | 1038_V | 1.017 | 0.10 |
| 836_H | 953_L | 1.017 | 0.10 |
| 15_M | 630_D | 1.015 | 0.10 |
| 56_Q | 92_G | 1.015 | 0.10 |
| 277_E | 304_K | 1.015 | 0.10 |
| 71_G | 158_W | 1.015 | 0.10 |
| 364_H | 712_E | 1.014 | 0.10 |
| 1022_V | 1029_S | 1.014 | 0.10 |
| 767_C | 776_E | 1.014 | 0.10 |
| 50_A | 777_D | 1.014 | 0.10 |
| 812_K | 915_S | 1.014 | 0.10 |
| 828_Y | 841_C | 1.014 | 0.10 |
| 399_C | 841_C | 1.014 | 0.10 |
| 141_Y | 147_I | 1.014 | 0.10 |
| 488_K | 517_E | 1.014 | 0.10 |
| 811_L | 869_I | 1.012 | 0.10 |
| 49_S | 1012_L | 1.012 | 0.10 |
| 277_E | 305_E | 1.012 | 0.10 |
| 408_G | 817_E | 1.012 | 0.10 |
| 128_L | 831_G | 1.011 | 0.10 |
| 341_T | 453_L | 1.011 | 0.10 |
| 924_V | 1011_V | 1.009 | 0.10 |
| 815_L | 961_H | 1.009 | 0.10 |
| 33_R | 86_E | 1.009 | 0.10 |
| 37_I | 157_S | 1.008 | 0.10 |
| 121_F | 345_E | 1.008 | 0.10 |
| 734_L | 741_A | 1.008 | 0.10 |
| 156_I | 888_L | 1.007 | 0.10 |
| 826_Y | 963_L | 1.007 | 0.10 |
| 98_M | 649_S | 1.007 | 0.10 |
| 45_L | 949_Y | 1.007 | 0.10 |
| 149_V | 294_P | 1.007 | 0.10 |
| 29_V | 35_G | 1.007 | 0.10 |
| 133_N | 1003_A | 1.007 | 0.10 |
| 831_G | 930_F | 1.005 | 0.10 |
| 256_R | 843_T | 1.005 | 0.10 |
| 78_W | 158_W | 1.005 | 0.10 |
| 468_Q | 471_T | 1.005 | 0.10 |
| 833_I | 963_L | 1.005 | 0.10 |
| 739_A | 858_I | 1.005 | 0.10 |
| 807_I | 959_L | 1.005 | 0.10 |
| 90_P | 115_Y | 1.004 | 0.10 |
| 76_D | 873_L | 1.004 | 0.10 |
| 38_M | 865_N | 1.004 | 0.10 |
| 605_P | 621_P | 1.002 | 0.10 |
| 396_M | 866_L | 1.001 | 0.10 |
| 906_A | 913_S | 1.001 | 0.10 |
| 188_R | 988_K | 1.001 | 0.10 |
| 92_G | 96_S | 1.001 | 0.10 |
| 90_P | 96_S | 1.001 | 0.10 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 4aezC | 3 | 0.2 | 100 | 0.823 | Contact Map |
| 3e7eA | 1 | 0.301 | 100 | 0.856 | Contact Map |
| 4a1gA | 4 | 0.1429 | 100 | 0.861 | Contact Map |
| 2wviA | 1 | 0.1524 | 100 | 0.89 | Contact Map |
| 3eslA | 2 | 0.1829 | 100 | 0.901 | Contact Map |
| 2izrA | 1 | 0.2543 | 99.9 | 0.93 | Contact Map |
| 2yabA | 2 | 0.2562 | 99.9 | 0.931 | Contact Map |
| 4neuA | 2 | 0.2543 | 99.9 | 0.931 | Contact Map |
| 1qpcA | 1 | 0.24 | 99.9 | 0.931 | Contact Map |
| 3byvA | 1 | 0.2705 | 99.9 | 0.932 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)