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OPENSEQ.org
YAFJ - Putative glutamine amidotransferase YafJ
UniProt: Q47147 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13147
Length: 255 (254)
Sequences: 700
Seq/Len: 2.76
YAFJ
Paralog alert: 0.15 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
39_T 104_T 5.459 1.00
71_S 74_V 2.452 1.00
241_M 244_E 2.441 1.00
75_V 106_A 2.31 1.00
128_T 131_E 2.111 1.00
194_T 224_T 2.079 1.00
41_Y 177_S 2.008 1.00
126_G 131_E 1.994 1.00
90_N 131_E 1.935 0.99
2_C 5_L 1.874 0.99
111_L 133_A 1.864 0.99
101_R 178_D 1.855 0.99
203_T 233_G 1.76 0.99
1_M 5_L 1.757 0.98
122_F 142_T 1.675 0.98
140_K 165_E 1.632 0.97
191_H 239_K 1.613 0.97
202_A 213_F 1.599 0.97
77_H 92_H 1.594 0.97
212_D 215_S 1.581 0.97
1_M 4_L 1.557 0.96
117_L 166_L 1.537 0.96
62_K 66_D 1.533 0.96
90_N 126_G 1.528 0.96
61_A 91_T 1.493 0.95
152_M 215_S 1.468 0.94
118_E 139_H 1.439 0.93
105_Y 134_F 1.434 0.93
5_L 18_S 1.429 0.93
61_A 231_L 1.403 0.92
55_S 91_T 1.386 0.91
6_G 182_V 1.363 0.91
189_N 229_Q 1.349 0.90
157_K 161_S 1.327 0.89
90_N 128_T 1.301 0.88
152_M 156_F 1.296 0.87
76_A 190_L 1.29 0.87
3_E 8_S 1.287 0.87
205_L 233_G 1.286 0.87
164_D 254_V 1.281 0.87
15_I 74_V 1.257 0.85
15_I 38_I 1.256 0.85
6_G 175_L 1.253 0.85
45_G 102_N 1.249 0.85
22_L 30_G 1.244 0.84
240_I 246_R 1.24 0.84
161_S 164_D 1.229 0.83
190_L 230_P 1.224 0.83
52_P 91_T 1.217 0.82
81_A 84_G 1.204 0.82
161_S 180_R 1.198 0.81
139_H 143_Q 1.185 0.80
22_L 25_R 1.181 0.80
249_C 252_E 1.169 0.79
50_K 104_T 1.162 0.78
232_T 235_E 1.159 0.78
201_V 210_E 1.153 0.78
39_T 176_L 1.141 0.76
205_L 210_E 1.134 0.76
107_H 130_S 1.134 0.76
40_F 47_R 1.132 0.76
34_D 134_F 1.129 0.75
84_G 173_N 1.125 0.75
32_H 78_I 1.122 0.75
8_S 73_S 1.119 0.75
77_H 90_N 1.109 0.74
39_T 75_V 1.106 0.73
41_Y 104_T 1.104 0.73
124_P 135_C 1.103 0.73
178_D 181_Y 1.101 0.73
47_R 71_S 1.098 0.73
86_V 176_L 1.096 0.72
7_M 40_F 1.095 0.72
19_F 63_L 1.088 0.72
161_S 165_E 1.083 0.71
32_H 56_F 1.082 0.71
143_Q 164_D 1.078 0.71
83_R 110_Q 1.071 0.70
2_C 6_G 1.07 0.70
155_V 159_I 1.069 0.70
46_C 205_L 1.067 0.69
1_M 6_G 1.066 0.69
41_Y 71_S 1.061 0.69
82_N 110_Q 1.059 0.69
126_G 134_F 1.059 0.69
55_S 77_H 1.057 0.68
140_K 144_R 1.056 0.68
196_R 222_V 1.054 0.68
40_F 71_S 1.052 0.68
33_K 57_N 1.05 0.68
157_K 180_R 1.049 0.68
162_L 166_L 1.049 0.68
117_L 120_G 1.048 0.67
82_N 130_S 1.046 0.67
25_R 29_T 1.044 0.67
41_Y 178_D 1.043 0.67
7_M 18_S 1.034 0.66
91_T 187_S 1.033 0.66
118_E 121_N 1.033 0.66
41_Y 179_G 1.032 0.66
16_C 54_P 1.031 0.66
76_A 191_H 1.03 0.65
71_S 177_S 1.029 0.65
75_V 175_L 1.029 0.65
137_L 163_A 1.029 0.65
201_V 246_R 1.027 0.65
3_E 41_Y 1.024 0.65
8_S 22_L 1.023 0.65
209_V 218_T 1.022 0.65
92_H 131_E 1.019 0.64
38_I 52_P 1.019 0.64
50_K 95_T 1.019 0.64
24_Q 28_G 1.012 0.63
222_V 225_V 1.006 0.63
159_I 245_W 1.005 0.63
28_G 252_E 1.004 0.63
114_Y 229_Q 1.002 0.62
57_N 121_N 1.002 0.62
106_A 175_L 1 0.62
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1te5A20.99221000.402Contact Map0.489
3mdnA40.8511000.466Contact Map0.574
1xffA20.81181000.625Contact Map0.491
2bplA30.81961000.633Contact Map0.461
1ao0A40.81961000.636Contact Map0.483
1ecfA20.87061000.642Contact Map0.456
1ea0A20.85199.80.744Contact Map0.274
1ofdA20.854999.80.747Contact Map0.282
1jgtA20.682499.70.765Contact Map0.361
1ct9A40.670699.70.772Contact Map0.525
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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