| UniProt: | Q46891 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13107 | ||
| Length: | 258 (255) | ||
| Sequences: | 5837 | ||
| Seq/Len: | 22.89 |
| YGBM
Paralog alert: 0.70 [within 20: 0.18] - ratio of genomes with paralogs Cluster includes: END4 FRLC HYI SGBU ULAE YCJR YGBM |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 220_N | 223_W | 3.381 | 1.00 | |
| 46_Q | 50_E | 3.275 | 1.00 | |
| 207_G | 215_D | 3.171 | 1.00 | |
| 174_F | 201_A | 3.148 | 1.00 | |
| 92_E | 136_H | 2.947 | 1.00 | |
| 22_A | 52_N | 2.945 | 1.00 | |
| 88_D | 132_R | 2.877 | 1.00 | |
| 31_A | 236_W | 2.822 | 1.00 | |
| 123_I | 167_E | 2.776 | 1.00 | |
| 92_E | 132_R | 2.749 | 1.00 | |
| 47_K | 51_Q | 2.509 | 1.00 | |
| 81_H | 85_A | 2.405 | 1.00 | |
| 163_A | 167_E | 2.321 | 1.00 | |
| 139_R | 174_F | 2.226 | 1.00 | |
| 131_D | 170_R | 2.164 | 1.00 | |
| 18_I | 48_Q | 2.119 | 1.00 | |
| 16_P | 19_E | 2.082 | 1.00 | |
| 194_R | 227_L | 2.05 | 1.00 | |
| 48_Q | 52_N | 2.044 | 1.00 | |
| 22_A | 26_K | 1.998 | 1.00 | |
| 139_R | 201_A | 1.994 | 1.00 | |
| 188_N | 191_H | 1.953 | 1.00 | |
| 95_L | 136_H | 1.924 | 1.00 | |
| 84_H | 128_Y | 1.912 | 1.00 | |
| 141_L | 201_A | 1.893 | 1.00 | |
| 120_A | 167_E | 1.878 | 1.00 | |
| 194_R | 230_E | 1.87 | 1.00 | |
| 119_R | 163_A | 1.844 | 1.00 | |
| 101_Q | 141_L | 1.841 | 1.00 | |
| 130_A | 173_V | 1.822 | 1.00 | |
| 49_L | 56_L | 1.781 | 1.00 | |
| 48_Q | 51_Q | 1.78 | 1.00 | |
| 117_R | 120_A | 1.717 | 1.00 | |
| 94_A | 99_C | 1.694 | 1.00 | |
| 119_R | 167_E | 1.69 | 1.00 | |
| 203_V | 228_F | 1.69 | 1.00 | |
| 80_E | 125_N | 1.664 | 1.00 | |
| 91_L | 133_F | 1.636 | 1.00 | |
| 227_L | 230_E | 1.625 | 1.00 | |
| 25_R | 52_N | 1.622 | 1.00 | |
| 159_Y | 195_D | 1.615 | 1.00 | |
| 226_R | 230_E | 1.615 | 1.00 | |
| 91_L | 136_H | 1.61 | 1.00 | |
| 132_R | 136_H | 1.588 | 1.00 | |
| 85_A | 89_L | 1.563 | 1.00 | |
| 248_E | 252_G | 1.549 | 1.00 | |
| 21_F | 52_N | 1.539 | 1.00 | |
| 121_V | 124_D | 1.536 | 1.00 | |
| 41_S | 44_Q | 1.532 | 1.00 | |
| 44_Q | 47_K | 1.526 | 1.00 | |
| 18_I | 51_Q | 1.519 | 1.00 | |
| 162_L | 166_E | 1.509 | 1.00 | |
| 130_A | 168_V | 1.489 | 1.00 | |
| 191_H | 195_D | 1.488 | 1.00 | |
| 42_T | 96_A | 1.486 | 1.00 | |
| 43_L | 96_A | 1.484 | 1.00 | |
| 89_L | 92_E | 1.478 | 1.00 | |
| 207_G | 217_G | 1.476 | 1.00 | |
| 141_L | 176_Q | 1.473 | 1.00 | |
| 134_A | 170_R | 1.47 | 1.00 | |
| 134_A | 172_N | 1.454 | 1.00 | |
| 123_I | 127_R | 1.45 | 1.00 | |
| 18_I | 44_Q | 1.444 | 1.00 | |
| 47_K | 50_E | 1.421 | 1.00 | |
| 22_A | 48_Q | 1.416 | 1.00 | |
| 131_D | 135_P | 1.415 | 1.00 | |
| 3_R | 55_T | 1.369 | 0.99 | |
| 84_H | 88_D | 1.365 | 0.99 | |
| 174_F | 199_K | 1.358 | 0.99 | |
| 114_D | 117_R | 1.353 | 0.99 | |
| 166_E | 199_K | 1.347 | 0.99 | |
| 222_P | 226_R | 1.346 | 0.99 | |
| 120_A | 124_D | 1.322 | 0.99 | |
| 124_D | 127_R | 1.32 | 0.99 | |
| 127_R | 169_A | 1.313 | 0.99 | |
| 24_A | 29_F | 1.307 | 0.99 | |
| 49_L | 54_L | 1.301 | 0.99 | |
| 144_A | 182_A | 1.299 | 0.99 | |
| 29_F | 239_C | 1.298 | 0.99 | |
| 190_T | 223_W | 1.283 | 0.99 | |
| 132_R | 135_P | 1.282 | 0.99 | |
| 43_L | 47_K | 1.276 | 0.99 | |
| 23_A | 26_K | 1.275 | 0.99 | |
| 116_E | 120_A | 1.269 | 0.99 | |
| 91_L | 132_R | 1.26 | 0.99 | |
| 131_D | 134_A | 1.255 | 0.99 | |
| 157_S | 160_Q | 1.25 | 0.99 | |
| 19_E | 22_A | 1.246 | 0.98 | |
| 85_A | 88_D | 1.243 | 0.98 | |
| 252_G | 256_A | 1.231 | 0.98 | |
| 101_Q | 139_R | 1.229 | 0.98 | |
| 123_I | 168_V | 1.215 | 0.98 | |
| 79_R | 82_E | 1.209 | 0.98 | |
| 44_Q | 48_Q | 1.182 | 0.98 | |
| 88_D | 92_E | 1.177 | 0.98 | |
| 162_L | 195_D | 1.176 | 0.98 | |
| 191_H | 194_R | 1.175 | 0.98 | |
| 193_I | 227_L | 1.175 | 0.98 | |
| 227_L | 231_V | 1.169 | 0.97 | |
| 134_A | 171_D | 1.157 | 0.97 | |
| 179_T | 224_L | 1.155 | 0.97 | |
| 115_A | 160_Q | 1.152 | 0.97 | |
| 87_I | 129_A | 1.145 | 0.97 | |
| 92_E | 95_L | 1.143 | 0.97 | |
| 88_D | 128_Y | 1.143 | 0.97 | |
| 253_W | 256_A | 1.142 | 0.97 | |
| 177_L | 182_A | 1.136 | 0.97 | |
| 31_A | 57_A | 1.126 | 0.97 | |
| 46_Q | 96_A | 1.125 | 0.97 | |
| 21_F | 48_Q | 1.116 | 0.96 | |
| 156_S | 160_Q | 1.115 | 0.96 | |
| 92_E | 96_A | 1.103 | 0.96 | |
| 223_W | 227_L | 1.093 | 0.96 | |
| 39_N | 96_A | 1.091 | 0.96 | |
| 246_L | 249_E | 1.089 | 0.96 | |
| 161_A | 175_I | 1.083 | 0.96 | |
| 24_A | 32_V | 1.082 | 0.96 | |
| 91_L | 138_K | 1.08 | 0.95 | |
| 81_H | 128_Y | 1.077 | 0.95 | |
| 101_Q | 201_A | 1.072 | 0.95 | |
| 18_I | 22_A | 1.068 | 0.95 | |
| 94_A | 102_V | 1.062 | 0.95 | |
| 25_R | 53_H | 1.04 | 0.94 | |
| 162_L | 196_Y | 1.038 | 0.94 | |
| 49_L | 52_N | 1.037 | 0.94 | |
| 163_A | 166_E | 1.034 | 0.94 | |
| 88_D | 135_P | 1.033 | 0.94 | |
| 197_A | 231_V | 1.02 | 0.93 | |
| 46_Q | 98_N | 1.017 | 0.93 | |
| 193_I | 231_V | 1.015 | 0.93 | |
| 228_F | 231_V | 1.015 | 0.93 | |
| 78_G | 82_E | 1.006 | 0.93 | |
| 127_R | 170_R | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1k77A | 1 | 1 | 100 | 0.122 | Contact Map | 0.708 |
| 3ngfA | 2 | 0.9961 | 100 | 0.16 | Contact Map | 0.652 |
| 1i60A | 1 | 0.9574 | 100 | 0.208 | Contact Map | 0.679 |
| 2qulA | 4 | 0.9729 | 100 | 0.222 | Contact Map | 0.778 |
| 2hk0A | 4 | 0.969 | 100 | 0.223 | Contact Map | 0.738 |
| 3kwsA | 2 | 0.969 | 100 | 0.229 | Contact Map | 0.695 |
| 2zvrA | 2 | 0.9767 | 100 | 0.23 | Contact Map | 0.779 |
| 3vylA | 8 | 0.969 | 100 | 0.235 | Contact Map | 0.737 |
| 3qc0A | 1 | 0.9651 | 100 | 0.236 | Contact Map | 0.668 |
| 3vniA | 4 | 0.969 | 100 | 0.242 | Contact Map | 0.804 |
Sequence Conservation (Image Generated using WebLogo v3)