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SUFD - FeS cluster assembly protein SufD
UniProt: P77689 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13963
Length: 423 (395)
Sequences: 1716
Seq/Len: 4.34
SUFD
Paralog alert: 0.61 [within 20: 0.38] - ratio of genomes with paralogs
Cluster includes: SUFB SUFD
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
209_A 237_E 4.952 1.00
144_R 179_E 4.867 1.00
177_L 181_A 4.808 1.00
238_D 265_N 4.311 1.00
235_L 239_A 4.049 1.00
33_L 37_L 3.926 1.00
210_N 238_D 3.879 1.00
147_R 182_E 3.734 1.00
381_N 384_D 3.545 1.00
179_E 209_A 3.485 1.00
177_L 213_L 3.442 1.00
205_I 213_L 3.436 1.00
233_L 241_A 3.395 1.00
141_A 178_A 2.978 1.00
180_G 210_N 2.915 1.00
144_R 178_A 2.9 1.00
59_N 126_F 2.884 1.00
207_V 241_A 2.842 1.00
182_E 212_H 2.801 1.00
207_V 211_A 2.745 1.00
264_E 294_F 2.738 1.00
294_F 325_K 2.734 1.00
234_L 262_N 2.625 1.00
290_H 297_S 2.485 1.00
177_L 211_A 2.471 1.00
264_E 293_G 2.456 1.00
179_E 208_A 2.321 1.00
325_K 355_D 2.316 1.00
310_R 342_E 2.288 1.00
209_A 236_A 2.248 1.00
274_A 303_T 2.239 1.00
276_P 309_G 2.079 1.00
52_T 252_V 2.027 1.00
376_R 382_Q 1.996 1.00
212_H 240_T 1.991 1.00
237_E 265_N 1.988 1.00
310_R 344_D 1.968 1.00
262_N 291_N 1.93 1.00
289_E 320_A 1.916 1.00
130_T 172_R 1.916 1.00
291_N 320_A 1.907 1.00
237_E 264_E 1.876 1.00
267_T 296_N 1.871 1.00
34_Q 38_R 1.851 1.00
108_V 140_I 1.834 1.00
145_G 180_G 1.829 1.00
240_T 267_T 1.815 1.00
32_H 131_E 1.797 1.00
324_I 355_D 1.71 0.99
41_L 54_L 1.681 0.99
276_P 282_C 1.68 0.99
177_L 183_A 1.679 0.99
72_Q 75_D 1.677 0.99
107_E 141_A 1.675 0.99
207_V 239_A 1.672 0.99
35_Q 38_R 1.644 0.99
326_T 356_V 1.636 0.99
324_I 353_A 1.623 0.99
264_E 292_K 1.614 0.99
236_A 262_N 1.605 0.99
380_I 388_M 1.604 0.99
319_V 358_C 1.592 0.99
265_N 294_F 1.585 0.99
28_Q 131_E 1.565 0.99
207_V 213_L 1.563 0.99
345_T 362_A 1.547 0.98
266_S 292_K 1.546 0.98
322_H 353_A 1.536 0.98
31_Q 34_Q 1.533 0.98
34_Q 37_L 1.53 0.98
308_K 340_L 1.515 0.98
382_Q 386_Q 1.514 0.98
183_A 213_L 1.5 0.98
351_I 358_C 1.499 0.98
181_A 213_L 1.491 0.98
35_Q 39_T 1.489 0.98
323_A 326_T 1.485 0.98
141_A 176_D 1.484 0.98
261_L 295_C 1.473 0.98
319_V 351_I 1.47 0.98
279_N 308_K 1.456 0.97
58_I 61_Q 1.454 0.97
142_V 177_L 1.423 0.97
305_V 309_G 1.419 0.97
298_R 327_D 1.417 0.97
388_M 398_T 1.412 0.97
250_G 253_L 1.398 0.96
153_L 188_H 1.387 0.96
329_Q 359_S 1.36 0.96
99_D 102_E 1.346 0.95
106_Y 142_V 1.337 0.95
119_D 206_N 1.333 0.95
77_L 84_V 1.329 0.95
259_T 268_L 1.321 0.95
77_L 85_R 1.317 0.95
207_V 235_L 1.308 0.94
367_I 389_I 1.294 0.94
312_V 346_K 1.292 0.94
52_T 281_V 1.286 0.94
305_V 343_V 1.285 0.94
261_L 292_K 1.252 0.92
236_A 239_A 1.243 0.92
210_N 265_N 1.241 0.92
208_A 236_A 1.233 0.92
145_G 179_E 1.222 0.91
318_N 352_Y 1.201 0.90
142_V 183_A 1.199 0.90
281_V 312_V 1.193 0.90
175_L 205_I 1.182 0.89
184_T 216_I 1.179 0.89
110_I 136_S 1.178 0.89
152_L 183_A 1.173 0.89
130_T 202_R 1.173 0.89
56_G 252_V 1.165 0.88
238_D 264_E 1.157 0.88
304_I 394_A 1.156 0.88
175_L 185_V 1.15 0.87
234_L 260_Q 1.141 0.87
107_E 143_K 1.138 0.87
311_A 343_V 1.133 0.86
144_R 147_R 1.132 0.86
367_I 374_Y 1.129 0.86
142_V 148_P 1.117 0.85
110_I 113_D 1.111 0.85
319_V 326_T 1.104 0.84
319_V 354_D 1.101 0.84
221_E 227_H 1.096 0.84
349_L 358_C 1.094 0.84
156_H 189_F 1.092 0.84
176_D 206_N 1.092 0.84
260_Q 289_E 1.09 0.83
292_K 295_C 1.089 0.83
52_T 312_V 1.086 0.83
321_Q 340_L 1.082 0.83
142_V 181_A 1.081 0.83
325_K 354_D 1.072 0.82
319_V 330_M 1.068 0.82
120_A 206_N 1.068 0.82
177_L 207_V 1.064 0.81
172_R 204_T 1.062 0.81
284_T 301_H 1.055 0.81
351_I 356_V 1.055 0.81
353_A 356_V 1.051 0.80
144_R 380_I 1.047 0.80
273_L 302_K 1.045 0.80
31_Q 35_Q 1.044 0.80
235_L 241_A 1.041 0.79
179_E 210_N 1.041 0.79
151_P 184_T 1.037 0.79
324_I 354_D 1.03 0.78
295_C 326_T 1.03 0.78
330_M 358_C 1.028 0.78
147_R 212_H 1.022 0.78
189_F 227_H 1.021 0.77
300_L 396_E 1.018 0.77
236_A 263_G 1.017 0.77
79_L 82_D 1.015 0.77
285_R 314_N 1.009 0.76
266_S 293_G 1.008 0.76
51_Y 346_K 1.003 0.76
205_I 241_A 1.001 0.75
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1vh4A20.99761000.114Contact Map0.779
4dn7A20.93621000.298Contact Map0.808
1ifyA10.111119.90.973Contact Map0.503
1u9lA20.134816.30.974Contact Map0.809
1rq8A10.1315.80.974Contact Map0
1wjiA10.141815.60.974Contact Map0.715
2ekkA10.111115.30.975Contact Map0.762
4k6mA20.148914.20.975Contact Map0
3proC20.132414.10.975Contact Map0.578
2g3qA10.096911.30.976Contact Map0.517
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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