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OPENSEQ.org
YAHJ - Uncharacterized protein YahJ
UniProt: P77554 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13594
Length: 460 (398)
Sequences: 3627
Seq/Len: 9.11
YAHJ
Paralog alert: 0.71 [within 20: 0.27] - ratio of genomes with paralogs
Cluster includes: ALLB CODA GUAD IADA NAGA PHNM PHYDA SSNA YAHJ
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
414_E 422_D 3.99 1.00
448_F 453_L 3.911 1.00
108_A 428_L 3.634 1.00
56_L 108_A 3.458 1.00
116_T 179_T 3.349 1.00
419_K 422_D 3.279 1.00
423_D 450_K 3.14 1.00
111_K 445_T 3.029 1.00
325_N 353_K 2.952 1.00
113_M 428_L 2.951 1.00
446_A 453_L 2.949 1.00
163_Q 201_A 2.834 1.00
91_A 420_A 2.82 1.00
59_V 108_A 2.716 1.00
348_K 352_D 2.697 1.00
85_Q 90_V 2.69 1.00
324_A 353_K 2.686 1.00
426_F 448_F 2.676 1.00
82_V 113_M 2.643 1.00
104_P 456_G 2.635 1.00
414_E 419_K 2.573 1.00
114_L 427_V 2.567 1.00
92_L 420_A 2.496 1.00
346_P 349_Q 2.492 1.00
82_V 418_P 2.464 1.00
58_N 107_D 2.458 1.00
418_P 426_F 2.451 1.00
84_I 426_F 2.395 1.00
114_L 429_V 2.334 1.00
409_L 412_K 2.219 1.00
167_E 205_R 2.217 1.00
59_V 113_M 2.206 1.00
57_D 105_H 2.195 1.00
404_G 414_E 2.195 1.00
87_G 423_D 2.186 1.00
312_L 350_L 2.184 1.00
82_V 426_F 2.136 1.00
57_D 81_T 2.074 1.00
335_A 358_M 2.067 1.00
120_M 335_A 2.039 1.00
108_A 113_M 2.033 1.00
314_T 349_Q 2.02 1.00
55_Y 83_E 2.018 1.00
295_E 330_Q 1.998 1.00
56_L 84_I 1.967 1.00
350_L 355_V 1.959 1.00
163_Q 205_R 1.957 1.00
77_T 80_Q 1.902 1.00
259_D 293_T 1.883 1.00
447_T 455_W 1.854 1.00
88_K 423_D 1.838 1.00
325_N 329_V 1.832 1.00
324_A 350_L 1.832 1.00
333_S 356_K 1.826 1.00
56_L 426_F 1.826 1.00
260_T 263_Q 1.823 1.00
228_E 267_D 1.814 1.00
80_Q 92_L 1.784 1.00
120_M 358_M 1.779 1.00
427_V 444_R 1.757 1.00
295_E 326_R 1.747 1.00
333_S 406_V 1.74 1.00
201_A 205_R 1.74 1.00
124_L 169_L 1.736 1.00
111_K 430_D 1.726 1.00
314_T 346_P 1.722 1.00
394_N 397_R 1.718 1.00
174_Q 449_H 1.715 1.00
427_V 447_T 1.697 1.00
380_A 398_S 1.695 1.00
175_S 455_W 1.695 1.00
174_Q 455_W 1.687 1.00
83_E 91_A 1.685 1.00
428_L 448_F 1.675 1.00
265_A 272_V 1.648 1.00
444_R 447_T 1.647 1.00
306_I 327_M 1.642 1.00
404_G 422_D 1.641 1.00
228_E 232_R 1.637 1.00
170_I 202_V 1.612 1.00
167_E 202_V 1.609 1.00
269_D 303_K 1.602 1.00
53_H 85_Q 1.595 1.00
430_D 445_T 1.588 1.00
112_L 431_A 1.583 1.00
400_F 404_G 1.578 1.00
264_I 267_D 1.575 1.00
61_L 82_V 1.574 1.00
263_Q 267_D 1.563 1.00
324_A 349_Q 1.546 1.00
449_H 454_V 1.542 1.00
349_Q 353_K 1.534 1.00
170_I 181_A 1.528 1.00
309_A 334_I 1.517 1.00
82_V 92_L 1.503 1.00
328_V 355_V 1.488 1.00
118_R 412_K 1.487 1.00
188_E 191_S 1.485 1.00
351_H 397_R 1.483 1.00
113_M 426_F 1.474 1.00
171_D 206_R 1.456 1.00
259_D 263_Q 1.442 0.99
111_K 428_L 1.422 0.99
256_K 259_D 1.395 0.99
356_K 405_D 1.39 0.99
328_V 353_K 1.38 0.99
79_R 95_N 1.378 0.99
291_V 326_R 1.378 0.99
284_V 288_N 1.357 0.99
90_V 420_A 1.34 0.99
339_P 382_L 1.339 0.99
53_H 83_E 1.326 0.99
226_K 229_P 1.325 0.99
61_L 80_Q 1.322 0.99
326_R 329_V 1.321 0.99
113_M 448_F 1.312 0.99
349_Q 352_D 1.305 0.99
163_Q 198_N 1.295 0.99
174_Q 454_V 1.292 0.99
378_E 381_N 1.28 0.99
232_R 267_D 1.277 0.98
229_P 232_R 1.275 0.98
173_L 181_A 1.271 0.98
279_T 342_T 1.261 0.98
81_T 96_K 1.258 0.98
163_Q 167_E 1.252 0.98
59_V 428_L 1.245 0.98
202_V 205_R 1.234 0.98
114_L 117_T 1.217 0.98
178_T 376_M 1.21 0.98
336_S 383_Y 1.209 0.98
271_G 408_P 1.208 0.98
143_T 146_D 1.208 0.98
54_Y 448_F 1.203 0.98
54_Y 84_I 1.193 0.97
453_L 456_G 1.193 0.97
358_M 406_V 1.191 0.97
377_L 380_A 1.179 0.97
326_R 330_Q 1.169 0.97
56_L 428_L 1.159 0.97
81_T 91_A 1.158 0.97
414_E 418_P 1.154 0.97
411_E 422_D 1.151 0.97
82_V 89_I 1.148 0.96
306_I 309_A 1.147 0.96
334_I 355_V 1.143 0.96
65_F 419_K 1.127 0.96
292_E 326_R 1.126 0.96
232_R 268_Y 1.126 0.96
94_E 97_L 1.125 0.96
216_A 254_M 1.123 0.96
93_R 96_K 1.123 0.96
163_Q 202_V 1.123 0.96
358_M 405_D 1.115 0.96
412_K 423_D 1.11 0.96
58_N 79_R 1.108 0.95
350_L 357_V 1.101 0.95
56_L 448_F 1.099 0.95
106_Y 448_F 1.097 0.95
254_M 257_S 1.096 0.95
193_L 234_A 1.093 0.95
144_I 342_T 1.093 0.95
397_R 400_F 1.084 0.95
233_E 237_A 1.082 0.95
179_T 447_T 1.074 0.94
92_L 418_P 1.072 0.94
173_L 178_T 1.058 0.94
116_T 449_H 1.055 0.94
182_R 407_L 1.052 0.94
170_I 203_L 1.052 0.94
262_F 266_L 1.045 0.93
261_M 272_V 1.044 0.93
324_A 355_V 1.041 0.93
345_M 350_L 1.037 0.93
328_V 354_G 1.037 0.93
380_A 402_A 1.032 0.93
333_S 358_M 1.03 0.93
315_L 325_N 1.029 0.93
198_N 201_A 1.025 0.92
233_E 236_Q 1.024 0.92
273_D 307_S 1.023 0.92
160_P 201_A 1.023 0.92
236_Q 268_Y 1.015 0.92
180_I 412_K 1.007 0.91
87_G 450_K 1.007 0.91
62_E 112_L 1.006 0.91
264_I 268_Y 1.001 0.91
376_M 402_A 1.001 0.91
359_T 383_Y 1 0.91
428_L 446_A 1 0.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1ra0A10.85871000.424Contact Map0.761
2qt3A20.8371000.438Contact Map0.803
4dzhA10.8371000.45Contact Map0.777
3h4uA20.89131000.472Contact Map0.782
2pajA10.851000.476Contact Map0.731
3ls9A20.82831000.478Contact Map0.78
2oodA10.81741000.478Contact Map0.71
2i9uA20.83261000.48Contact Map0.741
3lnpA10.85871000.481Contact Map0.801
4f0rA10.82391000.482Contact Map0.812
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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