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YDJJ - Uncharacterized zinc-type alcohol dehydrogenase-like protein YdjJ
UniProt: P77280 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13486
Length: 347 (339)
Sequences: 22651
Seq/Len: 66.82
YDJJ
Paralog alert: 0.83 [within 20: 0.37] - ratio of genomes with paralogs
Cluster includes: ACUI ADHP CURA FRMA GATD IDND QOR1 RSPB TDH YAHK YBDR YCJQ YDJJ YDJL YGGP YJGB YJJN YPHC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
323_D 326_Q 3.513 1.00
34_E 145_T 3.305 1.00
32_K 72_V 3.201 1.00
34_E 70_T 2.997 1.00
29_V 136_T 2.994 1.00
30_L 72_V 2.9 1.00
144_D 147_E 2.799 1.00
189_K 215_T 2.794 1.00
85_D 138_K 2.765 1.00
319_Y 330_E 2.653 1.00
207_A 211_Q 2.635 1.00
206_L 210_E 2.611 1.00
228_R 231_Q 2.54 1.00
82_K 85_D 2.534 1.00
26_E 76_S 2.462 1.00
32_K 70_T 2.456 1.00
146_M 318_I 2.447 1.00
86_R 139_L 2.437 1.00
27_D 77_R 2.413 1.00
9_Q 17_I 2.395 1.00
32_K 128_Y 2.358 1.00
172_I 188_C 2.317 1.00
80_K 133_E 2.302 1.00
302_E 306_S 2.29 1.00
171_K 194_T 2.265 1.00
26_E 77_R 2.259 1.00
21_I 128_Y 2.256 1.00
320_D 323_D 2.209 1.00
142_N 305_S 2.197 1.00
167_K 170_K 2.144 1.00
203_E 207_A 2.12 1.00
67_C 124_A 2.106 1.00
173_I 238_A 2.098 1.00
23_V 73_A 2.097 1.00
317_H 330_E 2.096 1.00
86_R 145_T 2.08 1.00
185_L 214_A 2.045 1.00
170_K 263_K 2.015 1.00
25_K 28_E 1.998 1.00
326_Q 329_E 1.995 1.00
68_A 145_T 1.977 1.00
258_V 264_I 1.976 1.00
207_A 210_E 1.972 1.00
319_Y 327_A 1.959 1.00
30_L 130_C 1.951 1.00
173_I 199_V 1.944 1.00
9_Q 15_K 1.932 1.00
203_E 219_N 1.925 1.00
72_V 128_Y 1.875 1.00
200_D 206_L 1.841 1.00
7_I 17_I 1.831 1.00
329_E 333_N 1.83 1.00
147_E 312_K 1.799 1.00
239_D 259_M 1.78 1.00
206_L 217_V 1.776 1.00
139_L 148_G 1.762 1.00
86_R 141_D 1.75 1.00
154_A 183_M 1.748 1.00
75_G 78_V 1.74 1.00
73_A 83_P 1.735 1.00
74_V 83_P 1.716 1.00
81_F 138_K 1.709 1.00
164_A 240_I 1.708 1.00
67_C 89_I 1.706 1.00
263_K 285_V 1.696 1.00
223_E 228_R 1.685 1.00
326_Q 330_E 1.68 1.00
258_V 262_G 1.664 1.00
208_M 211_Q 1.661 1.00
219_N 222_K 1.651 1.00
139_L 145_T 1.651 1.00
190_C 308_R 1.644 1.00
224_D 227_A 1.643 1.00
24_P 130_C 1.642 1.00
28_E 132_P 1.638 1.00
197_A 238_A 1.624 1.00
175_L 254_A 1.623 1.00
258_V 284_E 1.616 1.00
47_E 332_V 1.607 1.00
194_T 216_V 1.58 1.00
216_V 232_F 1.576 1.00
185_L 198_V 1.569 1.00
263_K 287_I 1.564 1.00
241_V 254_A 1.561 1.00
70_T 86_R 1.538 1.00
71_V 81_F 1.534 1.00
203_E 222_K 1.526 1.00
125_L 328_F 1.523 1.00
318_I 344_K 1.522 1.00
28_E 130_C 1.519 1.00
33_V 67_C 1.517 1.00
81_F 85_D 1.496 1.00
27_D 132_P 1.491 1.00
30_L 128_Y 1.489 1.00
98_C 101_C 1.487 1.00
35_Y 146_M 1.482 1.00
30_L 73_A 1.468 1.00
302_E 305_S 1.437 1.00
330_E 335_K 1.433 1.00
29_V 81_F 1.428 1.00
177_A 198_V 1.408 1.00
24_P 30_L 1.406 0.99
70_T 145_T 1.405 0.99
24_P 28_E 1.38 0.99
95_C 98_C 1.38 0.99
325_Q 329_E 1.376 0.99
171_K 197_A 1.375 0.99
241_V 258_V 1.365 0.99
171_K 195_E 1.346 0.99
201_V 220_G 1.34 0.99
184_T 242_F 1.325 0.99
81_F 136_T 1.32 0.99
166_V 193_A 1.317 0.99
195_E 216_V 1.316 0.99
6_A 18_S 1.307 0.99
34_E 86_R 1.306 0.99
227_A 231_Q 1.305 0.99
316_T 330_E 1.297 0.99
31_I 69_G 1.294 0.99
46_F 328_F 1.29 0.99
98_C 109_C 1.256 0.99
101_C 109_C 1.25 0.99
198_V 214_A 1.243 0.98
38_I 327_A 1.243 0.98
35_Y 344_K 1.24 0.98
146_M 344_K 1.235 0.98
162_M 299_V 1.234 0.98
131_H 136_T 1.234 0.98
35_Y 145_T 1.229 0.98
27_D 133_E 1.229 0.98
6_A 127_H 1.221 0.98
175_L 199_V 1.213 0.98
210_E 217_V 1.205 0.98
194_T 215_T 1.197 0.98
6_A 322_R 1.193 0.98
303_A 308_R 1.185 0.98
203_E 206_L 1.183 0.98
21_I 30_L 1.179 0.98
10_V 13_T 1.178 0.98
211_Q 313_S 1.174 0.98
171_K 239_D 1.162 0.97
190_C 303_A 1.157 0.97
310_D 313_S 1.142 0.97
243_E 246_G 1.133 0.97
228_R 232_F 1.132 0.97
33_V 129_L 1.126 0.97
164_A 265_M 1.118 0.96
174_I 184_T 1.116 0.96
16_I 322_R 1.108 0.96
37_G 66_E 1.091 0.96
210_E 216_V 1.078 0.95
201_V 221_A 1.077 0.95
170_K 239_D 1.073 0.95
299_V 302_E 1.06 0.95
95_C 101_C 1.059 0.95
39_C 65_H 1.053 0.95
31_I 87_V 1.053 0.95
74_V 78_V 1.049 0.94
34_E 68_A 1.045 0.94
204_K 207_A 1.04 0.94
39_C 66_E 1.036 0.94
298_P 302_E 1.034 0.94
72_V 83_P 1.026 0.94
32_K 127_H 1.019 0.93
224_D 228_R 1.015 0.93
197_A 216_V 1.011 0.93
166_V 170_K 1.007 0.93
125_L 324_V 1.005 0.93
174_I 188_C 1.004 0.93
188_C 193_A 1.002 0.92
206_L 219_N 1.001 0.92
82_K 138_K 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4ej6A10.96831000.086Contact Map0.783
4ilkA20.97121000.089Contact Map0.787
4a2cA20.95681000.099Contact Map0.755
3m6iA20.98271000.099Contact Map0.811
3ukoA20.97981000.101Contact Map0.737
1cdoA20.97411000.105Contact Map0.799
1e3iA20.97121000.108Contact Map0.819
1vj0A40.97411000.108Contact Map0.769
4gi2A20.98271000.109Contact Map0.799
2d8aA10.97981000.11Contact Map0.804
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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