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OPENSEQ.org
YFGM - UPF0070 protein YfgM
UniProt: P76576 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14209
Length: 206 (205)
Sequences: 603
Seq/Len: 2.94
YFGM
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
173_D 176_G 4.743 1.00
103_E 106_K 4.1 1.00
140_Q 143_A 3.147 1.00
135_Q 147_T 2.928 1.00
198_Q 202_N 2.739 1.00
145_L 168_L 2.339 1.00
144_A 167_A 2.087 1.00
115_L 127_I 2.077 1.00
142_D 171_K 1.976 1.00
74_A 78_F 1.953 1.00
28_G 32_G 1.924 0.99
165_G 181_W 1.734 0.99
57_Y 86_Y 1.722 0.98
45_H 49_S 1.643 0.98
27_V 31_L 1.638 0.98
166_E 181_W 1.627 0.98
168_L 173_D 1.626 0.98
91_S 113_Q 1.622 0.97
181_W 200_K 1.599 0.97
168_L 176_G 1.599 0.97
135_Q 140_Q 1.543 0.96
98_F 110_Q 1.529 0.96
105_E 138_L 1.529 0.96
7_E 10_Q 1.516 0.96
162_D 197_M 1.478 0.95
168_L 180_A 1.474 0.95
113_Q 117_D 1.435 0.94
7_E 35_A 1.408 0.93
41_Y 45_H 1.406 0.93
17_F 21_N 1.396 0.93
161_A 164_R 1.382 0.92
166_E 200_K 1.34 0.91
41_Y 48_D 1.319 0.90
42_W 164_R 1.317 0.90
27_V 30_I 1.306 0.89
195_E 198_Q 1.3 0.89
108_A 131_L 1.297 0.89
19_A 38_G 1.271 0.87
126_V 156_W 1.27 0.87
91_S 110_Q 1.269 0.87
99_V 134_V 1.252 0.86
82_N 165_G 1.235 0.85
54_S 86_Y 1.233 0.85
104_L 137_Q 1.222 0.84
28_G 36_L 1.221 0.84
21_N 203_N 1.203 0.83
114_G 127_I 1.197 0.83
136_V 167_A 1.186 0.82
104_L 134_V 1.181 0.81
166_E 184_G 1.16 0.80
21_N 107_A 1.157 0.79
202_N 205_S 1.157 0.79
98_F 103_E 1.15 0.79
73_P 77_K 1.146 0.79
161_A 180_A 1.142 0.78
28_G 133_R 1.135 0.78
98_F 106_K 1.133 0.77
168_L 171_K 1.127 0.77
118_T 127_I 1.125 0.77
116_A 147_T 1.123 0.77
142_D 146_K 1.118 0.76
131_L 134_V 1.112 0.76
157_A 161_A 1.11 0.75
125_A 153_G 1.106 0.75
168_L 172_G 1.092 0.74
9_D 74_A 1.087 0.73
70_D 73_P 1.086 0.73
112_Q 147_T 1.082 0.73
108_A 134_V 1.08 0.73
29_V 40_R 1.075 0.72
30_I 73_P 1.069 0.71
199_M 202_N 1.066 0.71
17_F 125_A 1.066 0.71
19_A 23_K 1.064 0.71
165_G 184_G 1.058 0.70
127_I 197_M 1.048 0.69
24_A 32_G 1.047 0.69
145_L 171_K 1.037 0.68
27_V 35_A 1.035 0.68
53_A 84_N 1.031 0.67
105_E 109_A 1.031 0.67
188_D 194_S 1.027 0.67
35_A 187_S 1.027 0.67
143_A 146_K 1.026 0.67
95_A 165_G 1.026 0.67
123_L 127_I 1.022 0.66
171_K 176_G 1.021 0.66
53_A 83_K 1.021 0.66
164_R 180_A 1.019 0.66
128_N 135_Q 1.018 0.66
114_G 119_S 1.008 0.65
133_R 163_L 1.003 0.64
15_K 18_F 1.001 0.64
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3qkyA10.815598.20.824Contact Map0.613
2xevA30.582598.10.825Contact Map0.805
2yhcA10.757397.60.843Contact Map0.519
1w3bA20.713697.40.85Contact Map0.751
4i2zA10.611797.40.85Contact Map0.771
1pc2A10.548597.30.852Contact Map0.554
2c2lA40.577797.30.854Contact Map0.821
4f3vA20.946697.20.855Contact Map0.684
3gyzA20.728297.20.856Contact Map0.814
2vsyA20.66597.20.856Contact Map0.761
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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