| UniProt: | P76340 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG14045 | ||
| Length: | 223 (219) | ||
| Sequences: | 28027 | ||
| Seq/Len: | 127.98 |
| YEDW
Paralog alert: 0.94 [within 20: 0.56] - ratio of genomes with paralogs Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 13_Q | 29_A | 3.485 | 1.00 | |
| 13_Q | 31_S | 2.784 | 1.00 | |
| 17_T | 29_A | 2.591 | 1.00 | |
| 34_R | 56_G | 2.544 | 1.00 | |
| 6_I | 36_G | 2.47 | 1.00 | |
| 32_D | 56_G | 2.409 | 1.00 | |
| 151_K | 154_Q | 2.336 | 1.00 | |
| 186_N | 189_D | 2.31 | 1.00 | |
| 57_M | 65_T | 2.304 | 1.00 | |
| 169_R | 189_D | 2.27 | 1.00 | |
| 28_D | 45_Y | 2.266 | 1.00 | |
| 17_T | 21_S | 2.228 | 1.00 | |
| 152_E | 198_K | 2.214 | 1.00 | |
| 83_V | 103_S | 2.184 | 1.00 | |
| 33_G | 57_M | 2.111 | 1.00 | |
| 86_R | 106_E | 2.065 | 1.00 | |
| 32_D | 35_D | 2.056 | 1.00 | |
| 41_L | 69_A | 2.024 | 1.00 | |
| 37_L | 65_T | 1.976 | 1.00 | |
| 19_G | 104_F | 1.959 | 1.00 | |
| 129_G | 142_D | 1.93 | 1.00 | |
| 2_K | 26_V | 1.923 | 1.00 | |
| 58_D | 61_Q | 1.878 | 1.00 | |
| 209_A | 219_V | 1.877 | 1.00 | |
| 31_S | 35_D | 1.836 | 1.00 | |
| 157_W | 161_S | 1.821 | 1.00 | |
| 30_V | 39_L | 1.787 | 1.00 | |
| 138_S | 145_S | 1.777 | 1.00 | |
| 126_E | 131_R | 1.764 | 1.00 | |
| 191_A | 194_R | 1.753 | 1.00 | |
| 76_C | 89_G | 1.752 | 1.00 | |
| 47_L | 111_V | 1.73 | 1.00 | |
| 2_K | 28_D | 1.724 | 1.00 | |
| 20_L | 111_V | 1.692 | 1.00 | |
| 63_L | 74_V | 1.691 | 1.00 | |
| 209_A | 217_S | 1.681 | 1.00 | |
| 75_I | 114_Q | 1.668 | 1.00 | |
| 50_L | 62_I | 1.666 | 1.00 | |
| 158_L | 172_I | 1.608 | 1.00 | |
| 53_M | 80_R | 1.608 | 1.00 | |
| 95_N | 117_Q | 1.6 | 1.00 | |
| 162_R | 165_E | 1.596 | 1.00 | |
| 91_D | 112_R | 1.59 | 1.00 | |
| 52_I | 76_C | 1.586 | 1.00 | |
| 132_M | 160_A | 1.575 | 1.00 | |
| 50_L | 63_L | 1.569 | 1.00 | |
| 158_L | 175_E | 1.554 | 1.00 | |
| 4_L | 30_V | 1.55 | 1.00 | |
| 131_R | 140_S | 1.54 | 1.00 | |
| 65_T | 68_T | 1.525 | 1.00 | |
| 63_L | 76_C | 1.498 | 1.00 | |
| 80_R | 85_D | 1.483 | 1.00 | |
| 168_P | 171_V | 1.459 | 1.00 | |
| 48_I | 72_T | 1.456 | 1.00 | |
| 76_C | 94_A | 1.451 | 1.00 | |
| 33_G | 62_I | 1.41 | 1.00 | |
| 6_I | 54_L | 1.408 | 1.00 | |
| 7_E | 13_Q | 1.387 | 0.99 | |
| 67_R | 95_N | 1.381 | 0.99 | |
| 57_M | 61_Q | 1.379 | 0.99 | |
| 28_D | 39_L | 1.375 | 0.99 | |
| 167_I | 175_E | 1.371 | 0.99 | |
| 37_L | 62_I | 1.371 | 0.99 | |
| 96_D | 110_R | 1.357 | 0.99 | |
| 23_A | 108_L | 1.354 | 0.99 | |
| 60_W | 92_S | 1.341 | 0.99 | |
| 61_Q | 64_Q | 1.319 | 0.99 | |
| 65_T | 69_A | 1.296 | 0.99 | |
| 133_D | 136_S | 1.29 | 0.99 | |
| 39_L | 42_K | 1.275 | 0.99 | |
| 192_I | 196_R | 1.261 | 0.99 | |
| 34_R | 57_M | 1.256 | 0.99 | |
| 39_L | 43_D | 1.255 | 0.99 | |
| 52_I | 60_W | 1.253 | 0.99 | |
| 38_Y | 42_K | 1.251 | 0.99 | |
| 163_A | 167_I | 1.228 | 0.98 | |
| 158_L | 167_I | 1.205 | 0.98 | |
| 211_I | 217_S | 1.205 | 0.98 | |
| 25_Y | 112_R | 1.201 | 0.98 | |
| 24_G | 112_R | 1.178 | 0.98 | |
| 47_L | 115_L | 1.175 | 0.98 | |
| 40_A | 66_L | 1.167 | 0.97 | |
| 34_R | 38_Y | 1.165 | 0.97 | |
| 37_L | 57_M | 1.164 | 0.97 | |
| 82_S | 85_D | 1.146 | 0.97 | |
| 64_Q | 88_R | 1.133 | 0.97 | |
| 137_H | 154_Q | 1.133 | 0.97 | |
| 187_T | 191_A | 1.132 | 0.97 | |
| 134_S | 157_W | 1.124 | 0.97 | |
| 30_V | 36_G | 1.123 | 0.97 | |
| 28_D | 43_D | 1.111 | 0.96 | |
| 8_D | 51_D | 1.103 | 0.96 | |
| 114_Q | 117_Q | 1.101 | 0.96 | |
| 35_D | 38_Y | 1.101 | 0.96 | |
| 10_Q | 31_S | 1.095 | 0.96 | |
| 165_E | 171_V | 1.088 | 0.96 | |
| 137_H | 214_M | 1.085 | 0.96 | |
| 3_I | 25_Y | 1.084 | 0.96 | |
| 190_V | 193_R | 1.08 | 0.95 | |
| 149_T | 198_K | 1.078 | 0.95 | |
| 84_D | 88_R | 1.069 | 0.95 | |
| 60_W | 88_R | 1.063 | 0.95 | |
| 53_M | 79_A | 1.06 | 0.95 | |
| 6_I | 48_I | 1.06 | 0.95 | |
| 132_M | 153_F | 1.057 | 0.95 | |
| 140_S | 145_S | 1.056 | 0.95 | |
| 170_T | 185_T | 1.052 | 0.95 | |
| 4_L | 45_Y | 1.046 | 0.94 | |
| 158_L | 162_R | 1.043 | 0.94 | |
| 16_V | 77_L | 1.043 | 0.94 | |
| 4_L | 36_G | 1.043 | 0.94 | |
| 5_L | 27_I | 1.04 | 0.94 | |
| 36_G | 40_A | 1.04 | 0.94 | |
| 124_T | 131_R | 1.031 | 0.94 | |
| 83_V | 87_V | 1.018 | 0.93 | |
| 87_V | 105_S | 1.018 | 0.93 | |
| 127_I | 218_F | 1.015 | 0.93 | |
| 170_T | 174_S | 1.015 | 0.93 | |
| 35_D | 39_L | 1.009 | 0.93 | |
| 54_L | 62_I | 1.006 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3r0jA | 2 | 0.991 | 100 | 0.118 | Contact Map | 0.693 |
| 1ys7A | 2 | 0.991 | 100 | 0.121 | Contact Map | 0.78 |
| 2gwrA | 1 | 1 | 100 | 0.125 | Contact Map | 0.679 |
| 2oqrA | 1 | 0.9865 | 100 | 0.142 | Contact Map | 0.575 |
| 1kgsA | 1 | 0.991 | 100 | 0.149 | Contact Map | 0.723 |
| 2hqrA | 2 | 0.9731 | 100 | 0.153 | Contact Map | 0.687 |
| 4b09A | 12 | 1 | 100 | 0.159 | Contact Map | 0.678 |
| 3q9sA | 1 | 0.9507 | 100 | 0.178 | Contact Map | 0.681 |
| 1p2fA | 1 | 0.9686 | 100 | 0.18 | Contact Map | 0.748 |
| 3c3wA | 2 | 0.9507 | 100 | 0.245 | Contact Map | 0.629 |
Sequence Conservation (Image Generated using WebLogo v3)