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OPENSEQ.org

YEBZ - Inner membrane protein YebZ
UniProt: P76278 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14028
Length: 290 (290)
Sequences: 663
Seq/Len: 2.29

YEBZ
Paralog alert: 0.18 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
153_I 200_G 3.614 1.00
228_L 232_I 2.738 1.00
237_M 274_G 2.354 1.00
130_L 155_L 2.106 1.00
233_L 280_I 2.033 0.99
198_V 238_V 2.031 0.99
187_L 252_M 1.922 0.99
225_Q 228_L 1.801 0.98
236_I 273_I 1.753 0.98
16_S 57_S 1.723 0.97
162_F 274_G 1.721 0.97
150_N 208_N 1.706 0.97
187_L 263_F 1.624 0.96
227_L 234_V 1.623 0.96
187_L 248_L 1.598 0.95
194_G 241_A 1.596 0.95
191_S 245_R 1.587 0.95
191_S 267_T 1.584 0.95
233_L 277_V 1.58 0.95
70_G 198_V 1.515 0.93
26_Y 263_F 1.504 0.93
229_L 232_I 1.49 0.93
26_Y 252_M 1.48 0.92
226_L 280_I 1.47 0.92
240_I 282_S 1.455 0.91
263_F 266_M 1.447 0.91
194_G 244_N 1.417 0.90
94_W 208_N 1.41 0.90
80_N 83_Q 1.406 0.89
202_L 235_M 1.396 0.89
218_T 224_G 1.39 0.89
100_L 164_G 1.383 0.88
13_H 58_A 1.381 0.88
229_L 280_I 1.373 0.88
52_V 203_A 1.369 0.88
156_I 252_M 1.365 0.88
204_S 241_A 1.363 0.87
55_L 102_L 1.355 0.87
190_F 263_F 1.339 0.86
213_T 223_W 1.331 0.86
242_L 246_Y 1.325 0.85
147_H 194_G 1.316 0.85
80_N 84_A 1.313 0.85
234_V 246_Y 1.312 0.85
8_A 200_G 1.312 0.85
9_L 62_L 1.312 0.85
24_A 47_Q 1.296 0.84
19_L 166_L 1.292 0.83
97_Q 132_G 1.291 0.83
243_A 247_V 1.289 0.83
125_A 128_I 1.288 0.83
18_M 278_L 1.286 0.83
13_H 69_M 1.283 0.83
141_G 245_R 1.281 0.83
109_L 276_V 1.246 0.80
241_A 244_N 1.246 0.80
244_N 250_P 1.237 0.79
155_L 227_L 1.235 0.79
210_L 213_T 1.234 0.79
227_L 242_L 1.233 0.79
147_H 212_I 1.229 0.79
189_R 231_A 1.224 0.78
5_T 124_T 1.223 0.78
157_C 200_G 1.223 0.78
55_L 227_L 1.221 0.78
56_I 82_W 1.22 0.78
194_G 281_I 1.214 0.78
208_N 285_A 1.212 0.78
8_A 99_V 1.205 0.77
164_G 197_A 1.203 0.77
56_I 200_G 1.198 0.76
105_L 221_T 1.191 0.76
282_S 285_A 1.189 0.76
238_V 241_A 1.187 0.75
234_V 281_I 1.184 0.75
281_I 284_L 1.171 0.74
244_N 248_L 1.166 0.74
26_Y 274_G 1.165 0.74
141_G 289_P 1.165 0.74
129_L 151_H 1.156 0.73
162_F 278_L 1.155 0.73
96_W 100_L 1.154 0.73
137_T 225_Q 1.15 0.72
20_V 24_A 1.15 0.72
212_I 279_V 1.145 0.72
277_V 281_I 1.141 0.71
49_H 107_V 1.137 0.71
164_G 194_G 1.134 0.71
8_A 102_L 1.132 0.70
21_F 159_A 1.122 0.69
68_L 208_N 1.121 0.69
200_G 280_I 1.121 0.69
282_S 286_T 1.117 0.69
264_V 278_L 1.117 0.69
147_H 244_N 1.115 0.69
201_V 241_A 1.111 0.68
281_I 285_A 1.109 0.68
88_T 91_G 1.108 0.68
141_G 208_N 1.101 0.67
123_T 276_V 1.1 0.67
46_L 232_I 1.1 0.67
208_N 245_R 1.099 0.67
194_G 287_L 1.099 0.67
90_F 130_L 1.095 0.67
15_T 109_L 1.094 0.67
212_I 241_A 1.093 0.67
24_A 27_G 1.092 0.66
67_G 72_G 1.089 0.66
103_V 159_A 1.087 0.66
106_I 273_I 1.086 0.66
225_Q 229_L 1.084 0.66
47_Q 279_V 1.08 0.65
30_L 90_F 1.077 0.65
8_A 12_I 1.076 0.65
10_R 227_L 1.071 0.64
149_T 212_I 1.07 0.64
53_W 239_V 1.067 0.64
190_F 241_A 1.067 0.64
147_H 287_L 1.06 0.63
247_V 251_R 1.058 0.63
97_Q 241_A 1.054 0.62
72_G 290_F 1.048 0.62
90_F 274_G 1.046 0.62
56_I 162_F 1.043 0.61
239_V 243_A 1.034 0.60
210_L 271_W 1.033 0.60
112_P 115_M 1.03 0.60
194_G 237_M 1.029 0.60
186_A 204_S 1.029 0.60
206_V 229_L 1.024 0.59
222_Y 225_Q 1.022 0.59
241_A 266_M 1.017 0.58
269_L 276_V 1.016 0.58
177_G 279_V 1.016 0.58
203_A 253_R 1.016 0.58
240_I 273_I 1.012 0.58
78_S 243_A 1.012 0.58
17_L 129_L 1.006 0.57
103_V 269_L 1.006 0.57
276_V 280_I 1.006 0.57
14_F 281_I 1.005 0.57
52_V 56_I 1.005 0.57
53_W 110_M 1.004 0.57
241_A 286_T 1.004 0.57
66_G 72_G 1.002 0.57
206_V 231_A 1.001 0.56
25_M 123_T 1.001 0.56
115_M 128_I 1.001 0.56
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2m7gA10.07931.90.968Contact Map0.358
3o0rB10.393110.973Contact Map0.276
3pcvA10.23790.80.974Contact Map0.292
1afoA20.13790.70.975Contact Map0.251
1r5jA20.20690.70.975Contact Map0
2af4C20.20690.70.976Contact Map0
2gr8A60.14140.60.976Contact Map0.442
3arcI20.1310.60.977Contact Map0.426
1fftB20.35170.60.977Contact Map0.196
2l9uA20.11380.50.978Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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