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OPENSEQ.org

YDJX - TVP38/TMEM64 family membrane protein YdjX
UniProt: P76219 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14000
Length: 236 (216)
Sequences: 902
Seq/Len: 4.18

YDJX
Paralog alert: 0.13 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: YDJX YDJZ
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
52_I 84_L 2.534 1.00
51_Y 72_G 2.509 1.00
157_A 160_P 2.071 1.00
82_T 174_V 1.99 1.00
52_I 87_I 1.918 1.00
48_Y 84_L 1.876 1.00
165_S 169_T 1.86 1.00
77_G 81_G 1.83 1.00
47_G 76_F 1.826 1.00
40_I 47_G 1.784 1.00
104_G 107_L 1.78 1.00
130_I 164_I 1.768 0.99
94_S 158_F 1.75 0.99
119_Q 123_K 1.736 0.99
78_P 81_G 1.661 0.99
109_L 122_E 1.628 0.99
145_N 148_N 1.609 0.99
78_P 82_T 1.583 0.99
200_G 204_F 1.576 0.99
105_R 122_E 1.536 0.98
86_L 170_L 1.521 0.98
80_L 83_L 1.505 0.98
94_S 162_T 1.486 0.98
55_F 69_V 1.48 0.98
86_L 89_A 1.473 0.97
16_L 20_A 1.462 0.97
96_S 152_G 1.454 0.97
8_L 11_C 1.445 0.97
56_I 91_L 1.441 0.97
84_L 87_I 1.399 0.96
89_A 169_T 1.399 0.96
132_F 136_T 1.393 0.96
86_L 166_A 1.392 0.96
137_R 148_N 1.388 0.96
122_E 129_G 1.367 0.96
81_G 177_T 1.362 0.95
51_Y 76_F 1.352 0.95
16_L 21_I 1.335 0.95
36_L 75_V 1.329 0.95
143_P 148_N 1.317 0.94
69_V 172_G 1.306 0.94
137_R 165_S 1.304 0.94
104_G 111_Y 1.302 0.94
109_L 153_L 1.299 0.94
52_I 88_A 1.293 0.93
117_T 120_A 1.28 0.93
69_V 173_I 1.279 0.93
58_A 145_N 1.262 0.92
7_F 19_Y 1.26 0.92
11_C 19_Y 1.256 0.92
51_Y 73_G 1.23 0.91
87_I 166_A 1.229 0.91
73_G 177_T 1.22 0.91
8_L 12_L 1.22 0.91
80_L 84_L 1.216 0.90
100_A 152_G 1.211 0.90
164_I 168_T 1.202 0.90
69_V 85_S 1.192 0.89
7_F 11_C 1.182 0.89
144_Y 169_T 1.175 0.88
92_A 140_P 1.175 0.88
162_T 166_A 1.168 0.88
66_S 169_T 1.166 0.88
172_G 203_L 1.16 0.87
147_Q 161_Y 1.158 0.87
9_F 15_A 1.153 0.87
85_S 177_T 1.149 0.87
55_F 143_P 1.149 0.87
81_G 89_A 1.148 0.87
133_L 164_I 1.146 0.87
101_R 152_G 1.137 0.86
56_I 88_A 1.127 0.85
93_S 148_N 1.118 0.85
130_I 163_L 1.115 0.84
159_W 163_L 1.113 0.84
49_S 53_L 1.108 0.84
7_F 10_A 1.102 0.83
16_L 19_Y 1.101 0.83
79_L 82_T 1.096 0.83
44_G 47_G 1.096 0.83
12_L 15_A 1.091 0.83
62_L 145_N 1.09 0.83
137_R 144_Y 1.09 0.83
62_L 66_S 1.088 0.82
14_F 19_Y 1.064 0.80
73_G 81_G 1.059 0.80
70_I 206_L 1.058 0.80
50_L 54_L 1.056 0.80
105_R 108_L 1.055 0.80
79_L 83_L 1.053 0.79
18_I 29_L 1.046 0.79
55_F 68_L 1.043 0.79
17_V 23_A 1.037 0.78
97_F 154_T 1.034 0.78
10_A 18_I 1.031 0.77
122_E 155_T 1.021 0.76
19_Y 23_A 1.02 0.76
132_F 147_Q 1.02 0.76
16_L 23_A 1.02 0.76
134_I 168_T 1.019 0.76
15_A 23_A 1.016 0.76
203_L 206_L 1.012 0.76
22_H 28_D 1.011 0.75
20_A 24_F 1.009 0.75
55_F 137_R 1.008 0.75
151_Y 154_T 1.006 0.75
104_G 152_G 1.006 0.75
11_C 23_A 1.004 0.75
6_K 12_L 1.003 0.75
145_N 149_Y 1.002 0.75
207_V 210_A 1.001 0.74
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
4dveA30.665323.30.946Contact Map0.361
2m20A20.207618.40.948Contact Map0.312
3rlbA20.720318.40.948Contact Map0.313
2xq2A10.7966160.95Contact Map0.162
4k0jA60.847514.20.951Contact Map0.094
4huqS10.699211.20.953Contact Map0.539
4eneA20.5212110.953Contact Map0.104
4dx5A30.82210.90.953Contact Map0.177
3k3fA10.711910.80.953Contact Map0.203
3w4tA10.49159.10.955Contact Map0.283

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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