May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
SUCP - Putative sucrose phosphorylase
UniProt: P76041 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13910
Length: 559 (507)
Sequences: 3055
Seq/Len: 6.03
SUCP
Paralog alert: 0.64 [within 20: 0.13] - ratio of genomes with paralogs
Cluster includes: AMY2 GLGX MALZ SUCP TREC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
159_D 187_R 5.46 1.00
117_Q 221_K 5.209 1.00
124_H 224_E 4.625 1.00
134_M 155_F 4.51 1.00
410_A 472_E 4.11 1.00
116_I 120_G 3.853 1.00
427_L 461_D 3.822 1.00
249_H 289_E 3.427 1.00
113_W 221_K 3.386 1.00
91_P 105_Q 3.348 1.00
64_K 118_Q 3.274 1.00
208_L 254_L 3.272 1.00
152_E 185_S 3.208 1.00
69_F 81_F 3.157 1.00
91_P 101_I 3.108 1.00
154_F 210_A 3.041 1.00
137_K 196_D 2.882 1.00
410_A 555_V 2.818 1.00
94_S 196_D 2.799 1.00
551_R 554_Q 2.746 1.00
215_L 255_L 2.738 1.00
89_F 106_V 2.707 1.00
180_Q 195_D 2.703 1.00
89_F 127_F 2.617 1.00
139_E 143_N 2.519 1.00
94_S 194_S 2.518 1.00
335_A 425_S 2.484 1.00
112_E 115_D 2.474 1.00
471_H 474_S 2.419 1.00
407_L 518_F 2.382 1.00
66_L 123_S 2.353 1.00
104_H 213_D 2.348 1.00
151_F 154_F 2.318 1.00
71_Q 474_S 2.285 1.00
470_Y 474_S 2.215 1.00
134_M 200_L 2.192 1.00
131_C 211_M 2.178 1.00
145_L 182_R 2.171 1.00
492_F 505_P 2.171 1.00
219_L 266_T 2.116 1.00
461_D 470_Y 2.109 1.00
414_S 557_W 2.066 1.00
434_A 462_E 2.05 1.00
210_A 213_D 2.029 1.00
256_R 260_D 2.023 1.00
181_M 186_T 1.989 1.00
131_C 215_L 1.954 1.00
84_V 123_S 1.952 1.00
144_Y 185_S 1.93 1.00
49_V 477_I 1.886 1.00
490_N 507_S 1.868 1.00
118_Q 122_C 1.864 1.00
94_S 137_K 1.852 1.00
152_E 182_R 1.851 1.00
143_N 149_P 1.849 1.00
411_I 518_F 1.84 1.00
435_G 462_E 1.831 1.00
104_H 210_A 1.83 1.00
105_Q 113_W 1.814 1.00
89_F 116_I 1.796 1.00
64_K 115_D 1.79 1.00
465_L 470_Y 1.789 1.00
81_F 84_V 1.78 1.00
90_Y 127_F 1.78 1.00
210_A 214_V 1.774 1.00
247_K 250_L 1.769 1.00
50_V 83_H 1.765 1.00
253_K 288_D 1.759 1.00
143_N 151_F 1.758 1.00
136_A 196_D 1.756 1.00
414_S 504_I 1.748 1.00
216_L 220_A 1.746 1.00
203_R 247_K 1.724 1.00
507_S 513_C 1.713 1.00
500_S 521_S 1.711 1.00
71_Q 465_L 1.709 1.00
518_F 555_V 1.7 1.00
114_Q 117_Q 1.692 1.00
134_M 207_V 1.683 1.00
253_K 289_E 1.669 1.00
71_Q 470_Y 1.663 1.00
47_S 488_P 1.659 1.00
464_T 471_H 1.645 1.00
175_L 178_P 1.636 1.00
247_K 251_I 1.625 1.00
104_H 214_V 1.612 1.00
492_F 507_S 1.606 0.99
505_P 513_C 1.605 0.99
131_C 228_L 1.596 0.99
465_L 471_H 1.592 0.99
104_H 217_C 1.586 0.99
409_H 473_L 1.585 0.99
430_R 455_I 1.571 0.99
319_Q 491_N 1.564 0.99
438_K 444_A 1.56 0.99
536_D 556_M 1.536 0.99
235_W 245_L 1.522 0.99
216_L 258_I 1.522 0.99
407_L 520_V 1.518 0.99
203_R 251_I 1.513 0.99
208_L 251_I 1.511 0.99
414_S 486_F 1.494 0.99
82_S 481_R 1.484 0.99
410_A 476_L 1.483 0.99
136_A 198_I 1.479 0.99
91_P 102_D 1.467 0.99
505_P 515_T 1.452 0.99
428_G 469_V 1.449 0.99
438_K 442_N 1.443 0.99
154_F 206_E 1.429 0.99
503_R 517_L 1.428 0.99
500_S 525_Q 1.426 0.98
182_R 185_S 1.425 0.98
310_N 499_S 1.423 0.98
235_W 247_K 1.422 0.98
212_V 254_L 1.421 0.98
113_W 117_Q 1.413 0.98
153_D 204_S 1.406 0.98
220_A 262_V 1.403 0.98
508_N 511_G 1.401 0.98
48_D 82_S 1.392 0.98
405_F 469_V 1.391 0.98
281_A 287_D 1.389 0.98
91_P 107_A 1.384 0.98
193_F 233_F 1.38 0.98
230_A 233_F 1.372 0.98
414_S 476_L 1.367 0.98
334_L 408_A 1.364 0.98
269_I 420_A 1.356 0.98
102_D 105_Q 1.352 0.98
173_L 176_L 1.346 0.98
406_I 472_E 1.346 0.98
144_Y 157_A 1.345 0.98
541_V 551_R 1.339 0.97
146_Q 149_P 1.334 0.97
478_T 482_S 1.333 0.97
208_L 212_V 1.325 0.97
413_L 477_I 1.323 0.97
55_A 87_L 1.323 0.97
341_G 356_E 1.32 0.97
150_G 206_E 1.317 0.97
142_K 146_Q 1.317 0.97
483_H 512_N 1.31 0.97
439_L 452_S 1.301 0.97
358_V 405_F 1.299 0.97
120_G 125_L 1.283 0.97
53_T 69_F 1.283 0.97
216_L 262_V 1.277 0.96
220_A 263_A 1.268 0.96
244_H 278_D 1.266 0.96
498_N 525_Q 1.265 0.96
507_S 511_G 1.265 0.96
119_L 125_L 1.251 0.96
466_R 471_H 1.244 0.96
86_L 89_F 1.243 0.96
143_N 146_Q 1.241 0.96
270_T 290_A 1.241 0.96
52_I 55_A 1.239 0.96
126_M 267_V 1.239 0.96
228_L 290_A 1.239 0.96
474_S 478_T 1.238 0.95
414_S 518_F 1.232 0.95
475_R 478_T 1.23 0.95
211_M 214_V 1.229 0.95
131_C 255_L 1.227 0.95
541_V 554_Q 1.222 0.95
209_L 213_D 1.221 0.95
66_L 122_C 1.22 0.95
48_D 83_H 1.219 0.95
69_F 84_V 1.208 0.95
152_E 187_R 1.205 0.95
151_F 206_E 1.2 0.94
106_V 116_I 1.195 0.94
504_I 516_G 1.192 0.94
56_D 109_E 1.192 0.94
142_K 145_L 1.188 0.94
116_I 127_F 1.184 0.94
472_E 555_V 1.179 0.94
235_W 251_I 1.163 0.93
234_M 248_T 1.16 0.93
237_E 247_K 1.159 0.93
402_C 406_I 1.158 0.93
449_K 452_S 1.149 0.93
139_E 142_K 1.146 0.92
485_E 514_L 1.142 0.92
443_R 447_R 1.141 0.92
539_S 554_Q 1.139 0.92
465_L 474_S 1.134 0.92
143_N 147_Q 1.125 0.91
147_Q 185_S 1.125 0.91
173_L 178_P 1.121 0.91
232_G 273_N 1.118 0.91
461_D 465_L 1.116 0.91
526_H 549_T 1.116 0.91
206_E 209_L 1.115 0.91
536_D 539_S 1.111 0.91
319_Q 493_T 1.098 0.90
486_F 514_L 1.094 0.90
231_V 252_I 1.094 0.90
129_F 215_L 1.094 0.90
50_V 420_A 1.091 0.90
484_N 512_N 1.089 0.90
363_Q 522_K 1.088 0.90
278_D 281_A 1.084 0.89
433_Y 440_G 1.083 0.89
260_D 291_H 1.079 0.89
56_D 107_A 1.07 0.89
149_P 152_E 1.07 0.89
209_L 258_I 1.067 0.88
137_K 142_K 1.067 0.88
427_L 469_V 1.066 0.88
232_G 272_T 1.064 0.88
216_L 261_N 1.063 0.88
212_V 255_L 1.061 0.88
292_M 418_V 1.06 0.88
63_L 116_I 1.06 0.88
267_V 292_M 1.06 0.88
334_L 357_L 1.052 0.87
137_K 194_S 1.045 0.87
253_K 287_D 1.041 0.87
91_P 108_S 1.041 0.87
144_Y 149_P 1.04 0.87
231_V 234_M 1.039 0.87
485_E 512_N 1.039 0.87
273_N 339_G 1.036 0.86
160_P 181_M 1.031 0.86
93_S 101_I 1.028 0.86
294_Y 420_A 1.026 0.86
117_Q 121_E 1.026 0.86
146_Q 151_F 1.026 0.86
335_A 357_L 1.015 0.85
174_P 178_P 1.011 0.84
230_A 234_M 1.01 0.84
116_I 223_A 1.009 0.84
212_V 258_I 1.006 0.84
143_N 148_H 1.004 0.84
528_N 547_E 1.001 0.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3ucqA10.97141000.291Contact Map0.668
1g5aA10.95891000.295Contact Map0.658
3czgA10.96061000.3Contact Map0.665
3zo9A20.92311000.309Contact Map0.749
4mb1A10.82111000.334Contact Map0.8
2ze0A10.82111000.338Contact Map0.817
1uokA10.82471000.343Contact Map0.8
1m53A10.85151000.35Contact Map0.791
4aieA10.82291000.355Contact Map0.808
2zicA10.81571000.358Contact Map0.757
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 0.2836 seconds.