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OPENSEQ.org

YMGE - UPF0410 protein ymge
UniProt: P76011 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14338
Length: 84 (83)
Sequences: 1001
Seq/Len: 12.06

YMGE
Paralog alert: 0.50 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: YEAQ YMGE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
11_L 33_C 2.569 1.00
6_W 44_G 2.47 1.00
38_V 74_V 2.147 1.00
64_F 68_V 2.085 1.00
34_I 38_V 1.906 1.00
18_K 27_G 1.904 1.00
42_V 74_V 1.841 1.00
35_L 78_F 1.77 1.00
21_M 76_G 1.723 1.00
43_G 66_V 1.681 1.00
33_C 37_I 1.631 1.00
18_K 32_T 1.608 1.00
16_I 68_V 1.577 1.00
25_D 79_R 1.435 1.00
44_G 67_A 1.414 1.00
15_I 19_L 1.399 0.99
65_L 69_V 1.395 0.99
12_I 16_I 1.387 0.99
11_L 29_F 1.374 0.99
13_A 67_A 1.348 0.99
38_V 41_V 1.341 0.99
20_I 68_V 1.339 0.99
29_F 33_C 1.316 0.99
31_L 34_I 1.292 0.99
9_F 64_F 1.286 0.99
76_G 80_L 1.274 0.99
27_G 31_L 1.273 0.99
80_L 83_R 1.254 0.99
15_I 29_F 1.216 0.98
47_A 66_V 1.213 0.98
16_I 19_L 1.206 0.98
22_P 32_T 1.203 0.98
21_M 72_I 1.196 0.98
5_A 64_F 1.162 0.97
18_K 26_G 1.135 0.97
4_I 8_I 1.113 0.96
15_I 18_K 1.112 0.96
18_K 23_G 1.091 0.96
18_K 22_P 1.041 0.94
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4g1uA20.928665.70.803Contact Map0.155
2nq2A20.916765.20.804Contact Map0.285
2qi9A20.916743.20.828Contact Map0.319
4hzuS10.964326.80.846Contact Map0.183
4dveA30.988117.40.859Contact Map0.299
3b9wA10.976217.20.859Contact Map0.135
3rlbA20.964315.60.862Contact Map0.167
4huqS10.988114.20.864Contact Map0.127
3p5nA20.964310.80.871Contact Map0.313
3hd6A115.60.887Contact Map0.249

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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