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OPENSEQ.org

OPGC - Glucans biosynthesis protein C
UniProt: P75920 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13876
Length: 385 (369)
Sequences: 1141
Seq/Len: 3.09

OPGC
Paralog alert: 0.58 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: OPGC YIAH
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
8_R 13_D 5.017 1.00
88_V 92_G 3.534 1.00
357_E 361_R 3.457 1.00
26_F 59_R 2.539 1.00
56_H 59_R 2.51 1.00
64_F 145_V 2.327 1.00
322_L 351_I 2.293 1.00
92_G 147_V 2.237 1.00
87_R 150_T 2.19 1.00
141_W 145_V 2.118 1.00
153_C 224_F 2.067 1.00
318_V 352_A 2.058 1.00
98_A 318_V 1.988 1.00
17_A 309_V 1.965 1.00
314_F 356_Y 1.94 1.00
65_V 230_A 1.884 0.99
26_F 56_H 1.881 0.99
97_T 101_L 1.832 0.99
17_A 312_S 1.811 0.99
19_L 62_V 1.805 0.99
81_K 85_K 1.771 0.99
64_F 220_Y 1.763 0.99
85_K 89_E 1.758 0.99
322_L 355_L 1.652 0.98
64_F 146_L 1.607 0.98
96_L 253_L 1.6 0.97
22_L 59_R 1.58 0.97
347_F 350_G 1.568 0.97
239_L 242_T 1.56 0.97
101_L 321_P 1.556 0.97
26_F 60_M 1.547 0.97
25_P 345_L 1.541 0.97
88_V 147_V 1.53 0.96
8_R 16_R 1.523 0.96
23_G 59_R 1.52 0.96
311_A 356_Y 1.512 0.96
308_F 315_I 1.511 0.96
60_M 143_L 1.499 0.96
64_F 142_F 1.483 0.96
83_W 87_R 1.482 0.96
13_D 16_R 1.473 0.95
14_S 305_V 1.464 0.95
23_G 26_F 1.461 0.95
248_T 252_A 1.448 0.95
153_C 228_A 1.434 0.94
20_M 24_I 1.433 0.94
64_F 149_M 1.427 0.94
12_L 70_F 1.409 0.94
322_L 326_F 1.406 0.94
21_L 349_V 1.396 0.93
102_L 139_H 1.391 0.93
71_S 87_R 1.387 0.93
348_V 352_A 1.379 0.93
307_Y 357_E 1.374 0.93
60_M 146_L 1.373 0.93
19_L 139_H 1.365 0.92
362_I 365_L 1.355 0.92
145_V 149_M 1.338 0.91
16_R 91_V 1.335 0.91
139_H 319_H 1.329 0.91
91_V 146_L 1.323 0.91
24_I 315_I 1.322 0.91
343_C 351_I 1.32 0.90
12_L 69_Y 1.315 0.90
24_I 348_V 1.299 0.90
246_G 249_L 1.299 0.90
366_K 370_S 1.297 0.89
16_R 139_H 1.293 0.89
91_V 150_T 1.283 0.89
67_S 146_L 1.283 0.89
60_M 141_W 1.28 0.89
8_R 146_L 1.275 0.88
20_M 63_F 1.275 0.88
71_S 150_T 1.274 0.88
71_S 83_W 1.272 0.88
102_L 317_L 1.271 0.88
12_L 358_I 1.27 0.88
69_Y 290_V 1.264 0.88
141_W 146_L 1.263 0.88
138_S 320_H 1.26 0.88
102_L 154_V 1.255 0.87
26_F 141_W 1.242 0.86
55_I 59_R 1.239 0.86
8_R 70_F 1.231 0.86
94_P 147_V 1.22 0.85
32_Y 48_L 1.216 0.85
68_G 141_W 1.211 0.85
13_D 60_M 1.192 0.83
19_L 59_R 1.189 0.83
57_S 60_M 1.184 0.83
185_C 346_I 1.181 0.83
22_L 60_M 1.169 0.82
16_R 319_H 1.165 0.81
102_L 321_P 1.163 0.81
192_V 299_N 1.163 0.81
22_L 141_W 1.159 0.81
311_A 357_E 1.158 0.81
65_V 72_Y 1.155 0.81
314_F 352_A 1.155 0.81
285_W 339_L 1.151 0.80
309_V 312_S 1.149 0.80
205_L 208_G 1.147 0.80
32_Y 141_W 1.146 0.80
7_Q 292_S 1.146 0.80
83_W 94_P 1.143 0.80
293_F 297_L 1.142 0.79
23_G 56_H 1.142 0.79
323_T 327_G 1.141 0.79
27_H 67_S 1.139 0.79
87_R 94_P 1.131 0.79
57_S 70_F 1.127 0.78
141_W 187_G 1.124 0.78
22_L 26_F 1.124 0.78
96_L 226_L 1.119 0.78
67_S 224_F 1.115 0.77
142_F 145_V 1.111 0.77
185_C 249_L 1.111 0.77
68_G 227_G 1.109 0.77
30_L 138_S 1.108 0.77
224_F 317_L 1.106 0.76
15_I 290_V 1.104 0.76
23_G 63_F 1.104 0.76
139_H 316_Y 1.104 0.76
58_F 62_V 1.099 0.76
87_R 142_F 1.096 0.75
358_I 362_I 1.091 0.75
119_S 122_G 1.087 0.75
51_F 55_I 1.078 0.74
367_F 370_S 1.077 0.74
16_R 60_M 1.076 0.74
58_F 69_Y 1.073 0.73
132_L 141_W 1.072 0.73
50_L 181_V 1.071 0.73
144_L 150_T 1.07 0.73
20_M 23_G 1.066 0.73
151_T 154_V 1.065 0.72
69_Y 146_L 1.063 0.72
19_L 63_F 1.063 0.72
57_S 139_H 1.062 0.72
87_R 231_F 1.056 0.72
61_Q 223_F 1.055 0.71
16_R 66_I 1.053 0.71
120_W 230_A 1.046 0.71
326_F 347_F 1.046 0.71
307_Y 311_A 1.045 0.70
152_L 181_V 1.043 0.70
89_E 92_G 1.042 0.70
84_W 150_T 1.041 0.70
59_R 141_W 1.041 0.70
30_L 102_L 1.041 0.70
326_F 344_G 1.04 0.70
148_V 219_F 1.036 0.69
99_I 315_I 1.033 0.69
314_F 363_P 1.033 0.69
90_R 95_M 1.032 0.69
141_W 148_V 1.032 0.69
26_F 55_I 1.03 0.69
281_V 345_L 1.027 0.69
13_D 146_L 1.026 0.68
350_G 362_I 1.025 0.68
59_R 309_V 1.024 0.68
17_A 305_V 1.021 0.68
181_V 256_V 1.013 0.67
98_A 150_T 1.012 0.67
25_P 181_V 1.011 0.67
283_G 287_V 1.011 0.67
233_F 253_L 1.01 0.67
13_D 68_G 1.003 0.66
64_F 99_I 1.003 0.66
354_I 358_I 1.001 0.66
172_K 176_M 1 0.66
234_P 346_I 1 0.66
181_V 330_I 1 0.66
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
1btkA20.14292.10.972Contact Map0.16
4gxbB10.054520.973Contact Map
2l8sA10.12731.90.973Contact Map0.441
3udcA70.15841.80.973Contact Map0.315
2kncA10.13251.60.974Contact Map0.494
3pl8A10.15581.40.975Contact Map0.766
1m06J10.0391.20.976Contact Map
2lswA10.04161.20.976Contact Map
2p8qB10.04421.10.976Contact Map0.184
4j72A20.19221.10.977Contact Map0.317

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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