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OPENSEQ.org
YBHK - UPF0052 protein YbhK
UniProt: P75767 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13667
Length: 302 (295)
Sequences: 859
Seq/Len: 2.91
YBHK
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
210_L 213_T 3.711 1.00
13_V 183_A 3.538 1.00
141_I 162_Q 3.476 1.00
186_I 210_L 3.227 1.00
141_I 163_E 3.033 1.00
185_L 218_V 2.868 1.00
186_I 213_T 2.833 1.00
11_R 182_E 2.671 1.00
48_T 59_A 2.62 1.00
178_H 182_E 2.453 1.00
55_E 102_K 2.452 1.00
257_V 270_I 2.36 1.00
96_L 100_M 2.294 1.00
63_M 115_I 2.262 1.00
57_G 102_K 2.257 1.00
238_S 241_A 2.212 1.00
274_E 289_L 2.143 1.00
139_M 165_L 2.05 1.00
181_N 209_A 1.952 0.99
218_V 294_L 1.924 0.99
181_N 212_R 1.922 0.99
47_S 94_H 1.912 0.99
13_V 36_T 1.84 0.99
38_I 176_A 1.834 0.99
208_Q 212_R 1.827 0.99
172_A 177_V 1.823 0.99
129_I 176_A 1.806 0.99
178_H 181_N 1.795 0.99
63_M 111_P 1.746 0.99
256_I 293_A 1.709 0.98
180_I 206_I 1.645 0.98
194_Y 234_L 1.618 0.97
236_L 255_V 1.602 0.97
141_I 165_L 1.583 0.97
139_M 167_T 1.579 0.97
180_I 209_A 1.577 0.97
131_M 206_I 1.552 0.96
220_I 294_L 1.512 0.96
260_K 274_E 1.5 0.95
58_I 111_P 1.488 0.95
240_L 252_I 1.416 0.93
237_E 241_A 1.401 0.93
72_T 125_D 1.397 0.93
234_L 242_I 1.382 0.92
9_L 34_R 1.38 0.92
172_A 176_A 1.365 0.91
192_S 226_E 1.362 0.91
100_M 118_I 1.346 0.91
42_T 152_V 1.338 0.90
9_L 32_G 1.32 0.90
205_E 208_Q 1.301 0.89
142_D 148_V 1.291 0.88
177_V 181_N 1.286 0.88
211_R 248_G 1.274 0.87
166_L 190_P 1.273 0.87
81_F 118_I 1.264 0.87
38_I 279_S 1.248 0.86
96_L 118_I 1.248 0.86
143_D 160_P 1.248 0.86
172_A 205_E 1.234 0.85
162_Q 245_Q 1.22 0.84
220_I 290_L 1.208 0.83
36_T 129_I 1.197 0.82
185_L 294_L 1.19 0.82
241_A 245_Q 1.185 0.81
181_N 213_T 1.174 0.81
182_E 214_P 1.171 0.80
48_T 60_W 1.17 0.80
25_L 37_G 1.164 0.80
14_A 21_L 1.158 0.79
286_D 289_L 1.153 0.79
16_G 20_G 1.153 0.79
10_D 32_G 1.152 0.79
177_V 213_T 1.147 0.78
132_S 136_V 1.144 0.78
228_S 232_A 1.142 0.78
256_I 294_L 1.131 0.77
115_I 144_Q 1.122 0.76
207_A 248_G 1.12 0.76
242_I 246_Y 1.116 0.76
273_Q 296_K 1.115 0.76
235_K 238_S 1.111 0.75
144_Q 159_T 1.102 0.74
21_L 122_L 1.096 0.74
136_V 166_L 1.093 0.74
141_I 147_E 1.092 0.73
207_A 251_V 1.091 0.73
36_T 183_A 1.091 0.73
83_Y 106_H 1.091 0.73
164_L 199_P 1.086 0.73
207_A 247_V 1.084 0.73
67_L 128_L 1.083 0.73
166_L 205_E 1.078 0.72
116_N 175_E 1.077 0.72
6_L 9_L 1.076 0.72
112_L 175_E 1.075 0.72
50_R 90_E 1.073 0.72
21_L 39_V 1.072 0.71
190_P 223_L 1.072 0.71
194_Y 242_I 1.072 0.71
259_P 272_I 1.071 0.71
210_L 217_M 1.068 0.71
34_R 290_L 1.066 0.71
177_V 206_I 1.062 0.70
166_L 202_L 1.062 0.70
287_R 293_A 1.058 0.70
42_T 155_D 1.053 0.70
155_D 226_E 1.051 0.69
49_G 52_R 1.041 0.68
15_L 176_A 1.033 0.67
180_I 213_T 1.032 0.67
240_L 243_M 1.031 0.67
155_D 192_S 1.029 0.67
94_H 150_G 1.026 0.67
187_I 294_L 1.021 0.66
22_G 65_N 1.019 0.66
23_R 226_E 1.016 0.66
177_V 209_A 1.016 0.66
153_N 210_L 1.015 0.65
66_C 96_L 1.013 0.65
28_L 71_I 1.013 0.65
15_L 38_I 1.012 0.65
15_L 200_I 1.011 0.65
260_K 292_N 1.011 0.65
153_N 194_Y 1.008 0.65
122_L 236_L 1.007 0.65
292_N 296_K 1.006 0.64
231_A 234_L 1.005 0.64
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2p0yA10.72521000.17Contact Map0.677
2o2zA40.95361000.178Contact Map0.717
2q7xA20.92051000.182Contact Map0.645
2ppvA10.97021000.188Contact Map0.697
3c3dA40.87751000.358Contact Map0.515
4g6hA20.685438.50.969Contact Map0.309
3dghA20.764927.60.971Contact Map0.286
4g9iA60.2219270.971Contact Map0.481
1pjqA20.913926.40.971Contact Map0.418
3kljA10.649250.972Contact Map0.284
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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