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OPENSEQ.org
YBHJ - Uncharacterized protein YbhJ
UniProt: P75764 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13666
Length: 753 (717)
Sequences: 1773
Seq/Len: 2.47
YBHJ
Paralog alert: 0.32 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: ACON1 YBHJ
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
291_D 294_A 6.768 1.00
189_H 289_S 5.406 1.00
225_V 287_C 4.57 1.00
259_E 262_N 4.026 1.00
214_N 286_G 3.737 1.00
265_A 271_Q 3.584 1.00
397_F 419_A 3.509 1.00
296_K 312_D 3.501 1.00
683_A 709_T 3.39 1.00
712_G 726_L 3.386 1.00
310_E 313_T 3.372 1.00
194_P 203_V 3.315 1.00
406_V 410_I 3.206 1.00
650_Q 677_M 3.171 1.00
258_E 262_N 3.151 1.00
716_H 722_T 3.074 1.00
256_T 274_C 2.952 1.00
635_V 661_E 2.94 1.00
410_I 415_I 2.934 1.00
712_G 724_I 2.917 1.00
710_F 726_L 2.857 1.00
711_K 723_E 2.839 1.00
377_G 408_D 2.796 1.00
62_A 130_I 2.794 1.00
186_V 286_G 2.764 1.00
407_A 411_G 2.737 1.00
709_T 725_T 2.677 1.00
191_T 289_S 2.663 1.00
299_I 314_L 2.657 1.00
659_I 726_L 2.652 1.00
695_Y 715_I 2.632 1.00
296_K 310_E 2.593 1.00
714_V 724_I 2.556 1.00
697_P 713_Y 2.409 1.00
160_M 251_S 2.403 1.00
210_A 288_I 2.395 1.00
711_K 725_T 2.368 1.00
408_D 411_G 2.35 1.00
713_Y 723_E 2.346 1.00
195_A 198_V 2.317 1.00
313_T 316_Q 2.265 1.00
390_Y 422_G 2.245 1.00
683_A 727_Y 2.234 1.00
538_V 695_Y 2.172 1.00
222_M 247_T 2.117 1.00
657_A 696_I 2.101 1.00
568_P 572_A 2.085 1.00
376_R 408_D 2.061 1.00
230_S 258_E 2.044 0.99
715_I 721_V 2.03 0.99
689_E 716_H 2.026 0.99
634_A 660_A 2.009 0.99
596_Q 599_A 2.004 0.99
97_C 388_A 1.991 0.99
189_H 227_P 1.975 0.99
691_G 717_E 1.971 0.99
695_Y 713_Y 1.929 0.99
622_D 626_T 1.918 0.99
397_F 401_A 1.885 0.99
537_I 695_Y 1.876 0.99
714_V 722_T 1.862 0.99
543_S 615_I 1.857 0.99
622_D 625_Q 1.837 0.99
38_A 185_V 1.822 0.99
543_S 608_V 1.82 0.99
38_A 221_V 1.81 0.98
193_K 231_A 1.791 0.98
193_K 227_P 1.769 0.98
541_V 544_K 1.767 0.98
209_G 308_V 1.756 0.98
319_T 480_T 1.756 0.98
596_Q 626_T 1.744 0.98
187_A 225_V 1.742 0.98
184_G 286_G 1.736 0.98
741_A 750_N 1.725 0.98
541_V 694_I 1.723 0.98
298_M 308_V 1.72 0.98
636_K 639_D 1.716 0.98
139_A 154_Y 1.688 0.97
186_V 214_N 1.688 0.97
716_H 720_P 1.67 0.97
189_H 225_V 1.667 0.97
194_P 198_V 1.666 0.97
585_S 589_A 1.665 0.97
535_D 698_G 1.657 0.97
206_A 298_M 1.652 0.97
417_R 422_G 1.643 0.97
390_Y 417_R 1.642 0.97
186_V 285_D 1.637 0.97
206_A 210_A 1.636 0.97
35_G 43_S 1.62 0.96
220_K 286_G 1.615 0.96
407_A 410_I 1.606 0.96
570_G 573_E 1.594 0.96
135_R 238_N 1.593 0.96
398_M 504_R 1.591 0.96
314_L 479_L 1.59 0.96
613_K 617_G 1.571 0.95
265_A 270_G 1.568 0.95
406_V 416_I 1.568 0.95
683_A 725_T 1.556 0.95
261_H 265_A 1.553 0.95
381_G 384_T 1.552 0.95
210_A 290_V 1.552 0.95
586_R 589_A 1.551 0.95
132_Q 363_G 1.55 0.95
681_Q 727_Y 1.544 0.95
687_T 722_T 1.533 0.95
569_I 652_V 1.524 0.94
206_A 209_G 1.521 0.94
234_T 259_E 1.515 0.94
713_Y 721_V 1.512 0.94
88_V 121_I 1.494 0.94
606_T 622_D 1.485 0.93
401_A 406_V 1.476 0.93
387_L 414_A 1.471 0.93
332_V 346_E 1.462 0.93
375_L 378_Q 1.453 0.92
88_V 140_G 1.441 0.92
693_Y 715_I 1.436 0.92
694_I 712_G 1.427 0.91
55_K 179_D 1.426 0.91
63_S 130_I 1.42 0.91
188_V 210_A 1.418 0.91
253_V 256_T 1.415 0.91
99_V 102_T 1.414 0.91
731_L 739_I 1.41 0.91
619_E 624_L 1.407 0.91
139_A 159_T 1.405 0.91
513_A 516_Q 1.397 0.90
432_I 452_K 1.396 0.90
153_R 252_S 1.385 0.90
651_R 656_L 1.384 0.90
471_A 485_L 1.371 0.89
230_S 277_N 1.371 0.89
542_C 655_G 1.369 0.89
741_A 747_F 1.368 0.89
575_T 649_C 1.365 0.89
369_I 405_V 1.365 0.89
688_F 694_I 1.364 0.89
127_I 505_V 1.358 0.89
697_P 723_E 1.358 0.89
435_G 454_A 1.357 0.88
36_T 39_W 1.356 0.88
70_G 74_T 1.353 0.88
97_C 356_I 1.345 0.88
233_S 259_E 1.337 0.87
584_V 589_A 1.334 0.87
589_A 605_L 1.333 0.87
249_C 252_S 1.332 0.87
42_L 51_M 1.332 0.87
194_P 231_A 1.322 0.87
511_K 517_P 1.321 0.87
498_V 502_K 1.317 0.86
244_T 252_S 1.315 0.86
244_T 247_T 1.311 0.86
105_G 109_V 1.301 0.85
545_I 549_V 1.298 0.85
36_T 185_V 1.294 0.85
317_N 321_I 1.286 0.85
694_I 724_I 1.283 0.84
317_N 457_Q 1.281 0.84
315_N 480_T 1.28 0.84
580_D 587_S 1.28 0.84
631_M 694_I 1.278 0.84
601_N 614_Q 1.275 0.84
332_V 335_G 1.27 0.84
290_V 294_A 1.269 0.84
375_L 412_A 1.266 0.83
481_S 484_E 1.264 0.83
354_Q 428_G 1.262 0.83
304_H 307_N 1.261 0.83
209_G 213_K 1.26 0.83
195_A 293_S 1.259 0.83
244_T 639_D 1.257 0.83
311_I 482_A 1.257 0.83
614_Q 617_G 1.255 0.83
475_N 480_T 1.252 0.82
633_Y 714_V 1.248 0.82
604_E 609_F 1.241 0.82
352_V 437_S 1.24 0.82
402_K 497_D 1.24 0.82
604_E 622_D 1.236 0.81
143_K 159_T 1.233 0.81
564_Y 570_G 1.222 0.80
189_H 287_C 1.222 0.80
349_R 478_Y 1.222 0.80
184_G 285_D 1.219 0.80
225_V 289_S 1.217 0.80
590_T 594_E 1.214 0.80
66_I 558_S 1.209 0.79
569_I 572_A 1.208 0.79
604_E 611_R 1.2 0.79
659_I 712_G 1.199 0.78
195_A 296_K 1.199 0.78
499_T 503_N 1.198 0.78
171_K 176_D 1.186 0.77
633_Y 659_I 1.186 0.77
241_D 253_V 1.184 0.77
678_L 739_I 1.182 0.77
87_Y 173_L 1.182 0.77
321_I 324_E 1.181 0.77
186_V 220_K 1.181 0.77
440_H 469_I 1.181 0.77
55_K 734_E 1.179 0.77
323_R 330_E 1.177 0.77
71_I 145_I 1.174 0.76
188_V 290_V 1.167 0.76
193_K 293_S 1.166 0.76
112_L 116_Q 1.161 0.75
669_R 735_E 1.161 0.75
237_R 257_D 1.16 0.75
306_S 639_D 1.158 0.75
356_I 422_G 1.157 0.75
306_S 548_E 1.151 0.74
299_I 459_S 1.142 0.74
633_Y 694_I 1.141 0.73
639_D 650_Q 1.141 0.73
69_V 73_Q 1.141 0.73
517_P 521_G 1.14 0.73
710_F 728_M 1.139 0.73
157_L 264_L 1.135 0.73
417_R 423_P 1.132 0.73
414_A 473_A 1.128 0.72
70_G 73_Q 1.125 0.72
241_D 252_S 1.121 0.72
631_M 657_A 1.121 0.72
206_A 290_V 1.12 0.71
316_Q 327_I 1.119 0.71
709_T 727_Y 1.119 0.71
516_Q 519_I 1.118 0.71
121_I 501_Y 1.118 0.71
109_V 519_I 1.114 0.71
698_G 710_F 1.113 0.71
104_N 108_H 1.112 0.71
315_N 478_Y 1.112 0.71
601_N 622_D 1.109 0.70
389_V 396_V 1.106 0.70
191_T 293_S 1.105 0.70
687_T 724_I 1.102 0.70
98_A 103_I 1.1 0.70
403_K 406_V 1.099 0.69
296_K 313_T 1.095 0.69
544_K 688_F 1.094 0.69
688_F 714_V 1.09 0.68
66_I 69_V 1.09 0.68
327_I 335_G 1.089 0.68
398_M 503_N 1.084 0.68
386_S 415_I 1.083 0.68
262_N 265_A 1.083 0.68
176_D 748_N 1.079 0.67
361_S 442_T 1.076 0.67
187_A 287_C 1.074 0.67
210_A 295_I 1.073 0.67
681_Q 684_E 1.072 0.67
438_I 472_T 1.071 0.67
67_T 425_F 1.07 0.66
594_E 618_Q 1.068 0.66
621_I 624_L 1.067 0.66
732_T 735_E 1.067 0.66
733_A 737_E 1.065 0.66
209_G 298_M 1.059 0.65
227_P 278_P 1.057 0.65
711_K 720_P 1.057 0.65
309_Y 321_I 1.056 0.65
317_N 327_I 1.056 0.65
737_E 740_K 1.053 0.65
235_D 266_L 1.05 0.64
540_K 628_I 1.044 0.64
637_P 668_Y 1.044 0.64
63_S 87_Y 1.044 0.64
146_L 178_W 1.043 0.64
564_Y 574_F 1.042 0.63
315_N 319_T 1.042 0.63
379_S 411_G 1.04 0.63
548_E 636_K 1.04 0.63
691_G 716_H 1.037 0.63
340_S 343_D 1.036 0.63
90_T 130_I 1.033 0.62
406_V 415_I 1.033 0.62
353_Q 453_P 1.032 0.62
229_V 541_V 1.032 0.62
319_T 345_V 1.028 0.62
606_T 610_A 1.028 0.62
317_N 325_I 1.025 0.62
352_V 479_L 1.024 0.61
548_E 639_D 1.02 0.61
328_E 332_V 1.02 0.61
582_G 585_S 1.019 0.61
580_D 584_V 1.019 0.61
315_N 326_E 1.017 0.61
512_G 515_Q 1.017 0.61
256_T 261_H 1.017 0.61
258_E 265_A 1.015 0.60
346_E 349_R 1.014 0.60
496_F 501_Y 1.013 0.60
535_D 697_P 1.012 0.60
535_D 700_K 1.011 0.60
320_D 323_R 1.009 0.60
703_L 706_P 1.008 0.60
402_K 495_A 1.006 0.59
162_V 688_F 1.005 0.59
355_G 473_A 1.005 0.59
357_I 387_L 1.004 0.59
534_T 715_I 1.004 0.59
331_R 335_G 1.002 0.59
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2b3yA20.95481000.254Contact Map0.673
1c96A10.91771000.264Contact Map0.689
1l5jA20.62951000.554Contact Map0.626
3vbaA60.21781000.846Contact Map0.608
2pkpA10.21381000.849Contact Map0.594
1v7lA20.21121000.851Contact Map0.656
3q3wA20.22181000.867Contact Map0.553
3h5jA20.21381000.868Contact Map0.541
2hcuA10.24971000.873Contact Map0.555
1g4dA10.067713.60.99Contact Map0
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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