May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
YBGQ - Uncharacterized outer membrane usher protein YbgQ
UniProt: P75750 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13313
Length: 815 (790)
Sequences: 1386
Seq/Len: 1.75
YBGQ
Paralog alert: 0.81 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: ELFC FIMD HTRE SFMD YAGX YBGQ YEHB YFCU YHCD YQIG YRAJ
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
82_C 107_C 4.502 1.00
270_I 282_I 4.103 1.00
661_L 691_I 3.823 1.00
278_A 318_E 3.747 1.00
620_D 636_S 3.684 1.00
234_E 248_T 3.22 1.00
651_H 687_V 3.136 1.00
342_V 371_W 3.108 1.00
739_V 780_V 2.959 1.00
247_Y 364_F 2.887 1.00
649_A 681_N 2.879 1.00
279_T 317_T 2.859 1.00
757_I 786_F 2.818 1.00
622_S 634_S 2.7 1.00
664_S 730_S 2.681 1.00
315_K 323_V 2.664 1.00
643_A 648_A 2.664 1.00
342_V 369_V 2.629 1.00
317_T 323_V 2.57 1.00
197_Y 212_G 2.551 1.00
275_Q 322_R 2.521 1.00
592_S 607_S 2.466 1.00
755_A 788_V 2.4 1.00
491_N 516_A 2.379 1.00
590_G 609_N 2.376 1.00
275_Q 324_N 2.364 1.00
757_I 775_A 2.337 1.00
283_S 288_V 2.335 1.00
416_S 462_Y 2.332 1.00
641_F 650_F 2.29 1.00
644_T 649_A 2.28 1.00
190_A 221_R 2.239 0.99
313_D 325_N 2.238 0.99
72_W 81_P 2.158 0.99
316_V 324_N 2.151 0.99
662_M 685_I 2.145 0.99
58_A 126_Q 2.108 0.99
640_S 651_H 2.099 0.99
185_G 194_R 2.093 0.99
282_I 301_I 2.083 0.99
743_I 797_I 2.078 0.99
155_G 726_I 2.075 0.99
55_V 72_W 2.072 0.99
193_L 219_L 2.04 0.99
410_D 430_R 2.006 0.99
346_L 367_N 1.985 0.98
660_R 726_I 1.971 0.98
380_Y 410_D 1.969 0.98
153_V 662_M 1.968 0.98
518_F 530_I 1.955 0.98
664_S 728_Y 1.95 0.98
55_V 120_F 1.947 0.98
283_S 315_K 1.874 0.98
564_Y 575_H 1.873 0.98
242_F 382_G 1.86 0.97
281_T 288_V 1.86 0.97
646_Y 664_S 1.825 0.97
737_K 782_E 1.806 0.97
186_I 193_L 1.786 0.97
786_F 797_I 1.782 0.96
143_W 146_P 1.778 0.96
220_F 229_K 1.774 0.96
619_W 637_W 1.758 0.96
94_K 97_I 1.752 0.96
644_T 685_I 1.739 0.96
428_S 450_R 1.737 0.96
658_E 723_E 1.729 0.96
617_G 637_W 1.728 0.96
193_L 217_T 1.728 0.96
251_A 345_K 1.71 0.95
665_T 668_V 1.691 0.95
665_T 733_S 1.691 0.95
38_D 42_L 1.69 0.95
130_S 295_P 1.687 0.95
231_T 253_A 1.686 0.95
428_S 452_S 1.685 0.95
427_L 453_D 1.663 0.94
141_E 305_N 1.65 0.94
743_I 775_A 1.63 0.93
495_Y 515_T 1.627 0.93
119_N 128_N 1.625 0.93
697_S 721_W 1.624 0.93
235_T 247_Y 1.622 0.93
281_T 317_T 1.61 0.93
257_R 723_E 1.599 0.93
640_S 687_V 1.597 0.92
739_V 799_L 1.588 0.92
270_I 312_L 1.574 0.92
563_G 578_S 1.573 0.92
54_F 69_K 1.569 0.92
195_S 214_I 1.564 0.91
645_Q 728_Y 1.564 0.91
256_D 341_Q 1.56 0.91
274_A 294_V 1.556 0.91
235_T 347_A 1.552 0.91
57_V 70_I 1.543 0.91
751_P 788_V 1.541 0.91
192_R 722_I 1.541 0.91
223_L 226_L 1.538 0.91
428_S 504_W 1.527 0.90
222_P 229_K 1.518 0.90
52_E 69_K 1.516 0.90
157_L 660_R 1.516 0.90
743_I 788_V 1.514 0.90
640_S 660_R 1.498 0.89
477_Q 502_T 1.495 0.89
757_I 788_V 1.492 0.89
328_V 336_L 1.488 0.88
271_S 300_I 1.481 0.88
478_T 501_Q 1.479 0.88
709_G 737_K 1.478 0.88
118_F 129_I 1.468 0.88
661_L 699_V 1.468 0.88
267_A 338_R 1.459 0.87
84_N 87_L 1.453 0.87
496_A 514_I 1.448 0.87
518_F 523_G 1.444 0.86
413_W 427_L 1.444 0.86
614_S 617_G 1.444 0.86
533_S 549_Y 1.443 0.86
256_D 343_R 1.443 0.86
313_D 327_Q 1.442 0.86
316_V 326_F 1.439 0.86
392_S 412_T 1.438 0.86
696_P 718_K 1.437 0.86
107_C 336_L 1.427 0.86
442_S 451_F 1.424 0.85
686_A 689_P 1.419 0.85
82_C 336_L 1.417 0.85
154_A 186_I 1.412 0.85
668_V 733_S 1.406 0.84
151_E 224_P 1.404 0.84
58_A 63_K 1.402 0.84
187_N 194_R 1.401 0.84
372_G 405_G 1.4 0.84
195_S 217_T 1.395 0.84
247_Y 347_A 1.39 0.83
515_T 518_F 1.385 0.83
536_T 546_N 1.382 0.83
487_I 491_N 1.378 0.83
158_M 184_A 1.377 0.83
671_I 680_T 1.372 0.82
745_N 751_P 1.371 0.82
222_P 722_I 1.368 0.82
721_W 727_G 1.366 0.82
642_T 660_R 1.36 0.82
641_F 648_A 1.358 0.81
712_V 715_N 1.356 0.81
743_I 751_P 1.355 0.81
87_L 91_F 1.355 0.81
440_T 498_L 1.354 0.81
314_V 328_V 1.35 0.81
164_A 635_S 1.348 0.81
640_S 654_S 1.346 0.81
121_D 128_N 1.344 0.81
646_Y 728_Y 1.341 0.80
277_N 318_E 1.335 0.80
179_N 182_G 1.333 0.80
377_T 399_Q 1.319 0.79
261_W 695_Q 1.311 0.78
654_S 660_R 1.308 0.78
243_D 458_S 1.308 0.78
736_G 779_G 1.308 0.78
153_V 726_I 1.293 0.77
247_Y 251_A 1.291 0.77
281_T 291_Q 1.282 0.76
154_A 645_Q 1.275 0.75
752_P 755_A 1.269 0.75
666_D 680_T 1.268 0.75
642_T 662_M 1.264 0.75
268_P 372_G 1.26 0.74
665_T 671_I 1.257 0.74
283_S 313_D 1.257 0.74
649_A 683_F 1.256 0.74
58_A 128_N 1.255 0.74
120_F 125_Q 1.253 0.74
339_Q 375_S 1.252 0.74
59_V 136_L 1.248 0.73
107_C 328_V 1.247 0.73
493_N 775_A 1.245 0.73
334_P 364_F 1.242 0.73
642_T 726_I 1.239 0.72
745_N 749_Q 1.238 0.72
223_L 252_L 1.237 0.72
785_L 796_I 1.235 0.72
614_S 619_W 1.234 0.72
396_G 405_G 1.232 0.72
663_V 673_V 1.231 0.72
154_A 726_I 1.228 0.71
56_S 59_V 1.224 0.71
649_A 685_I 1.223 0.71
160_Y 639_G 1.22 0.71
153_V 645_Q 1.217 0.70
82_C 328_V 1.211 0.70
440_T 485_Q 1.209 0.70
666_D 683_F 1.207 0.70
372_G 378_S 1.203 0.69
373_M 740_N 1.202 0.69
231_T 235_T 1.202 0.69
681_N 687_V 1.201 0.69
222_P 324_N 1.198 0.69
517_G 531_S 1.196 0.69
578_S 607_S 1.195 0.68
741_V 777_L 1.194 0.68
664_S 685_I 1.187 0.68
743_I 769_V 1.187 0.68
688_V 699_V 1.187 0.68
48_I 122_Q 1.186 0.68
784_Q 799_L 1.185 0.68
316_V 328_V 1.183 0.67
113_R 116_M 1.181 0.67
481_L 496_A 1.176 0.67
680_T 738_D 1.176 0.67
89_D 137_A 1.174 0.66
93_L 113_R 1.173 0.66
405_G 433_Y 1.173 0.66
752_P 790_W 1.17 0.66
350_Q 363_T 1.167 0.66
278_A 320_D 1.167 0.66
138_W 302_D 1.165 0.66
673_V 688_V 1.161 0.65
156_V 186_I 1.159 0.65
276_T 392_S 1.159 0.65
222_P 328_V 1.157 0.65
279_T 291_Q 1.154 0.65
644_T 647_G 1.154 0.65
380_Y 430_R 1.147 0.64
98_R 135_W 1.145 0.64
315_K 325_N 1.145 0.64
663_V 788_V 1.145 0.64
339_Q 374_L 1.142 0.63
135_W 298_P 1.142 0.63
228_S 344_Y 1.138 0.63
88_V 93_L 1.132 0.62
410_D 428_S 1.127 0.62
457_H 651_H 1.124 0.62
162_L 180_A 1.124 0.62
447_A 481_L 1.124 0.62
412_T 428_S 1.123 0.61
385_I 459_Y 1.118 0.61
380_Y 396_G 1.116 0.61
161_N 673_V 1.111 0.60
72_W 79_T 1.111 0.60
255_D 723_E 1.107 0.60
183_T 196_D 1.107 0.60
432_N 445_S 1.106 0.60
643_A 662_M 1.105 0.60
136_L 250_A 1.103 0.59
625_Y 631_S 1.102 0.59
157_L 726_I 1.102 0.59
222_P 225_Q 1.102 0.59
222_P 694_Y 1.101 0.59
738_D 778_S 1.095 0.59
755_A 790_W 1.094 0.58
759_Q 764_I 1.093 0.58
531_S 551_S 1.092 0.58
722_I 725_A 1.089 0.58
195_S 306_Q 1.086 0.58
444_I 482_S 1.085 0.57
331_A 336_L 1.085 0.57
476_K 504_W 1.085 0.57
250_A 392_S 1.084 0.57
445_S 480_S 1.084 0.57
50_P 605_Q 1.083 0.57
268_P 405_G 1.082 0.57
48_I 79_T 1.081 0.57
771_E 778_S 1.08 0.57
520_V 530_I 1.079 0.57
66_N 182_G 1.077 0.57
428_S 449_Y 1.077 0.57
736_G 776_W 1.075 0.56
136_L 295_P 1.073 0.56
158_M 286_G 1.073 0.56
644_T 662_M 1.073 0.56
352_R 528_I 1.073 0.56
619_W 638_S 1.071 0.56
440_T 447_A 1.07 0.56
232_L 250_A 1.07 0.56
260_P 372_G 1.069 0.56
320_D 726_I 1.069 0.56
662_M 728_Y 1.065 0.55
353_P 516_A 1.062 0.55
228_S 254_S 1.062 0.55
461_N 464_D 1.062 0.55
131_I 307_S 1.06 0.55
149_W 720_T 1.058 0.55
299_F 318_E 1.058 0.55
491_N 814_C 1.052 0.54
370_S 738_D 1.051 0.54
66_N 181_Y 1.049 0.54
149_W 753_L 1.049 0.54
248_T 366_S 1.049 0.54
221_R 230_L 1.049 0.54
495_Y 498_L 1.047 0.53
380_Y 753_L 1.042 0.53
241_I 394_A 1.04 0.53
113_R 135_W 1.04 0.53
568_N 572_S 1.038 0.52
214_I 234_E 1.033 0.52
562_V 577_M 1.033 0.52
268_P 396_G 1.033 0.52
416_S 531_S 1.032 0.52
353_P 677_L 1.031 0.52
353_P 678_D 1.031 0.52
52_E 71_N 1.03 0.52
104_I 112_S 1.028 0.51
129_I 175_S 1.026 0.51
649_A 662_M 1.025 0.51
157_L 642_T 1.025 0.51
409_F 429_Y 1.024 0.51
680_T 777_L 1.023 0.51
123_A 760_D 1.021 0.51
243_D 428_S 1.021 0.51
39_I 43_K 1.02 0.51
373_M 379_L 1.019 0.50
61_N 616_A 1.019 0.50
240_N 343_R 1.016 0.50
434_S 444_I 1.013 0.50
228_S 252_L 1.013 0.50
235_T 251_A 1.012 0.50
437_V 449_Y 1.009 0.49
548_I 566_M 1.008 0.49
398_G 408_S 1.008 0.49
305_N 636_S 1.005 0.49
156_V 643_A 1.004 0.49
401_M 493_N 1.003 0.49
756_D 765_S 1.001 0.48
652_R 678_D 1.001 0.48
347_A 368_E 1 0.48
125_Q 337_T 1 0.48
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3rfzB20.95461000.07Contact Map0.702
3fipA20.59751000.43Contact Map0.686
3fcgA20.10921000.83Contact Map0.787
4b0mA10.15831000.846Contact Map0.85
3bwuD10.147299.90.862Contact Map0.855
3l48A50.103199.60.902Contact Map0.949
2xetA20.096999.50.909Contact Map0.843
3e8vA10.090886.50.972Contact Map0.44
4kdwA10.138746.50.979Contact Map0.486
3pe9A40.114128.50.981Contact Map0.725
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 0.2254 seconds.