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YBGP - Uncharacterized fimbrial chaperone YbgP
UniProt: P75749 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13312
Length: 242 (217)
Sequences: 1353
Seq/Len: 6.24

YBGP
Paralog alert: 0.90 [within 20: 0.51] - ratio of genomes with paralogs
Cluster includes: ECPD ELFD FIMC SFMC YBGP YCBF YEHC YFCS YHCA YQIH YRAI
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
97_L 105_F 2.918 1.00
24_P 133_I 2.898 1.00
174_T 193_M 2.897 1.00
172_Y 195_A 2.831 1.00
104_L 193_M 2.698 1.00
136_F 193_M 2.585 1.00
101_R 197_F 2.544 1.00
32_N 35_D 2.537 1.00
195_A 198_S 2.458 1.00
29_I 107_Y 2.319 1.00
155_Q 166_K 2.314 1.00
166_K 199_T 2.258 1.00
57_I 135_L 2.213 1.00
51_Y 111_E 2.157 1.00
29_I 88_V 2.153 1.00
29_I 38_T 2.138 1.00
58_E 132_R 2.103 1.00
56_W 108_N 2.085 1.00
165_L 202_T 2.046 1.00
50_P 79_E 2.031 1.00
98_P 103_T 1.976 1.00
33_A 99_G 1.963 1.00
50_P 77_R 1.93 1.00
108_N 132_R 1.896 1.00
218_D 224_R 1.736 1.00
104_L 174_T 1.706 1.00
110_R 130_Q 1.697 1.00
142_L 171_Y 1.689 1.00
58_E 108_N 1.682 1.00
34_N 140_A 1.681 1.00
79_E 82_A 1.597 1.00
69_L 88_V 1.589 0.99
153_Q 169_T 1.575 0.99
156_V 165_L 1.571 0.99
164_T 201_N 1.57 0.99
98_P 101_R 1.559 0.99
154_L 165_L 1.546 0.99
88_V 135_L 1.536 0.99
24_P 109_M 1.522 0.99
32_N 38_T 1.512 0.99
90_K 93_S 1.51 0.99
149_K 173_L 1.48 0.99
159_Q 164_T 1.439 0.99
194_V 200_V 1.422 0.99
173_L 216_Y 1.41 0.98
157_S 164_T 1.399 0.98
22_V 78_L 1.394 0.98
218_D 222_A 1.392 0.98
23_Q 26_R 1.383 0.98
71_A 86_V 1.371 0.98
136_F 172_Y 1.367 0.98
174_T 216_Y 1.329 0.98
58_E 106_F 1.326 0.97
29_I 133_I 1.32 0.97
164_T 199_T 1.319 0.97
42_I 53_A 1.3 0.97
157_S 166_K 1.286 0.97
146_A 149_K 1.279 0.97
24_P 40_L 1.277 0.97
148_E 152_L 1.273 0.97
104_L 136_F 1.271 0.97
41_R 83_T 1.253 0.96
47_D 81_K 1.25 0.96
31_F 38_T 1.247 0.96
216_Y 224_R 1.243 0.96
106_F 110_R 1.208 0.95
162_Q 201_N 1.2 0.95
112_I 129_I 1.196 0.95
21_A 111_E 1.189 0.94
53_A 76_Q 1.175 0.94
156_V 178_L 1.164 0.94
84_S 110_R 1.159 0.93
50_P 114_P 1.143 0.93
90_K 96_Q 1.14 0.93
71_A 107_Y 1.134 0.92
86_V 107_Y 1.127 0.92
144_K 148_E 1.126 0.92
55_S 109_M 1.118 0.92
71_A 88_V 1.118 0.92
212_F 216_Y 1.115 0.91
59_N 63_E 1.104 0.91
159_Q 162_Q 1.103 0.91
86_V 109_M 1.08 0.90
85_Q 130_Q 1.08 0.90
194_V 198_S 1.076 0.89
55_S 86_V 1.076 0.89
149_K 216_Y 1.073 0.89
184_G 187_P 1.073 0.89
93_S 96_Q 1.07 0.89
102_E 138_R 1.069 0.89
175_I 194_V 1.063 0.89
156_V 193_M 1.061 0.89
154_L 175_I 1.059 0.88
84_S 111_E 1.059 0.88
180_R 212_F 1.053 0.88
136_F 174_T 1.028 0.86
90_K 137_W 1.021 0.86
52_L 110_R 1.02 0.86
58_E 62_G 1.018 0.86
46_S 111_E 1.017 0.86
31_F 89_V 1.013 0.85
51_Y 110_R 1.012 0.85
123_A 132_R 1.011 0.85
177_Y 215_G 1.007 0.85
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2xg5A10.88841000.189Contact Map0.798
4djmA80.92561000.207Contact Map0.812
1klfA80.84711000.209Contact Map0.79
2co7B10.89261000.219Contact Map0.739
1l4iA20.8431000.219Contact Map0.773
3gfuC20.86781000.222Contact Map0.684
4ay0A20.88841000.233Contact Map0.772
3q48A20.95871000.247Contact Map0.799
1mspA20.475246.90.949Contact Map0.557
2ys4A10.446319.70.958Contact Map0.396

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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