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OPENSEQ.org

FBPB - Putative ferric transport system permease protein FbpB (Fragment)
UniProt: P75681 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14277
Length: 115 (104)
Sequences: 18938
Seq/Len: 182.10

FBPB
Paralog alert: 0.91 [within 20: 0.68] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
20_R 24_H 4.204 1.00
8_D 26_L 2.85 1.00
12_L 21_T 2.829 1.00
17_G 20_R 2.694 1.00
61_R 69_N 2.469 1.00
19_L 23_T 2.447 1.00
18_S 21_T 2.387 1.00
11_S 21_T 2.244 1.00
16_A 20_R 2.181 1.00
51_A 55_L 2.078 1.00
75_E 78_V 2.064 1.00
7_L 29_L 2.044 1.00
11_S 16_A 2.034 1.00
5_K 8_D 1.895 1.00
12_L 18_S 1.846 1.00
20_R 23_T 1.817 1.00
36_S 40_Y 1.745 1.00
27_L 34_I 1.649 1.00
8_D 21_T 1.608 1.00
49_V 68_L 1.595 1.00
8_D 12_L 1.595 1.00
52_I 62_V 1.567 1.00
66_Y 70_R 1.504 1.00
70_R 73_D 1.469 1.00
6_S 9_E 1.465 1.00
41_S 45_A 1.39 0.99
11_S 25_I 1.372 0.99
48_T 51_A 1.349 0.99
62_V 65_A 1.339 0.99
57_T 60_T 1.327 0.99
48_T 52_I 1.324 0.99
3_I 29_L 1.29 0.99
95_F 99_W 1.265 0.99
17_G 21_T 1.257 0.99
70_R 75_E 1.235 0.98
22_I 27_L 1.209 0.98
66_Y 82_Y 1.207 0.98
61_R 66_Y 1.199 0.98
49_V 53_V 1.187 0.98
16_A 21_T 1.169 0.97
8_D 18_S 1.142 0.97
29_L 32_P 1.138 0.97
31_R 35_L 1.136 0.97
70_R 82_Y 1.116 0.96
5_K 9_E 1.098 0.96
70_R 78_V 1.085 0.96
61_R 65_A 1.032 0.94
34_I 38_L 1.03 0.94
31_R 100_L 1.014 0.93
21_T 26_L 1.006 0.93
41_S 44_R 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2onkC40.956599.80.271Contact Map0.798
3d31C20.947899.70.278Contact Map0.739
3rlfG10.965299.70.279Contact Map0.713
3rlfF10.921799.70.325Contact Map0.654
3tuiA40.904399.50.413Contact Map0.807
2l2tA20.37397.20.905Contact Map0.237
1ntcA20.26966.80.906Contact Map0.504
2m20A20.34784.40.914Contact Map0.034
4a4zA10.36523.10.92Contact Map0.346
2kluA10.37393.10.921Contact Map0

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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