| UniProt: | P71239 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13573 | ||
| Length: | 248 (215) | ||
| Sequences: | 15042 | ||
| Seq/Len: | 69.96 |
| WCAE
Paralog alert: 0.85 [within 20: 0.41] - ratio of genomes with paralogs Cluster includes: WBBL WCAA WCAE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 154_V | 158_K | 3.863 | 1.00 | |
| 13_L | 46_G | 3.216 | 1.00 | |
| 12_N | 91_S | 2.89 | 1.00 | |
| 9_A | 47_T | 2.741 | 1.00 | |
| 173_A | 177_K | 2.572 | 1.00 | |
| 30_E | 101_N | 2.358 | 1.00 | |
| 76_K | 80_M | 2.266 | 1.00 | |
| 96_H | 194_E | 2.208 | 1.00 | |
| 4_S | 83_G | 2.198 | 1.00 | |
| 112_N | 186_K | 2.171 | 1.00 | |
| 17_V | 21_A | 2.145 | 1.00 | |
| 46_G | 49_E | 2.142 | 1.00 | |
| 6_I | 77_G | 2.064 | 1.00 | |
| 21_A | 54_L | 2.051 | 1.00 | |
| 85_F | 106_L | 2.041 | 1.00 | |
| 48_R | 52_E | 2.028 | 1.00 | |
| 11_R | 44_N | 2.019 | 1.00 | |
| 39_V | 77_G | 1.92 | 1.00 | |
| 156_G | 183_Y | 1.891 | 1.00 | |
| 4_S | 35_E | 1.845 | 1.00 | |
| 7_T | 36_W | 1.837 | 1.00 | |
| 2_L | 84_K | 1.834 | 1.00 | |
| 17_V | 53_N | 1.827 | 1.00 | |
| 72_D | 164_L | 1.824 | 1.00 | |
| 95_F | 99_A | 1.804 | 1.00 | |
| 18_K | 196_S | 1.803 | 1.00 | |
| 85_F | 151_F | 1.797 | 1.00 | |
| 113_V | 153_P | 1.742 | 1.00 | |
| 68_N | 72_D | 1.74 | 1.00 | |
| 18_K | 94_I | 1.735 | 1.00 | |
| 38_V | 51_L | 1.708 | 1.00 | |
| 13_L | 50_Y | 1.697 | 1.00 | |
| 3_L | 103_V | 1.642 | 1.00 | |
| 105_K | 188_L | 1.642 | 1.00 | |
| 40_D | 63_V | 1.624 | 1.00 | |
| 87_L | 151_F | 1.618 | 1.00 | |
| 17_V | 50_Y | 1.611 | 1.00 | |
| 102_F | 151_F | 1.595 | 1.00 | |
| 105_K | 186_K | 1.58 | 1.00 | |
| 74_M | 90_N | 1.576 | 1.00 | |
| 7_T | 19_T | 1.575 | 1.00 | |
| 9_A | 12_N | 1.573 | 1.00 | |
| 159_K | 181_A | 1.566 | 1.00 | |
| 114_M | 185_F | 1.538 | 1.00 | |
| 64_S | 76_K | 1.517 | 1.00 | |
| 11_R | 43_S | 1.514 | 1.00 | |
| 40_D | 64_S | 1.511 | 1.00 | |
| 10_F | 67_D | 1.499 | 1.00 | |
| 79_A | 161_R | 1.498 | 1.00 | |
| 65_E | 68_N | 1.473 | 1.00 | |
| 17_V | 54_L | 1.47 | 1.00 | |
| 76_K | 79_A | 1.465 | 1.00 | |
| 31_D | 103_V | 1.454 | 1.00 | |
| 2_L | 33_S | 1.448 | 1.00 | |
| 78_I | 157_L | 1.439 | 1.00 | |
| 113_V | 183_Y | 1.437 | 1.00 | |
| 106_L | 151_F | 1.425 | 1.00 | |
| 120_L | 194_E | 1.418 | 1.00 | |
| 9_A | 38_V | 1.4 | 0.99 | |
| 155_S | 159_K | 1.385 | 0.99 | |
| 35_E | 83_G | 1.38 | 0.99 | |
| 71_Y | 170_S | 1.369 | 0.99 | |
| 40_D | 43_S | 1.368 | 0.99 | |
| 99_A | 102_F | 1.365 | 0.99 | |
| 101_N | 104_R | 1.365 | 0.99 | |
| 21_A | 28_Q | 1.354 | 0.99 | |
| 87_L | 100_A | 1.35 | 0.99 | |
| 70_I | 74_M | 1.344 | 0.99 | |
| 78_I | 86_A | 1.334 | 0.99 | |
| 74_M | 88_F | 1.323 | 0.99 | |
| 94_I | 194_E | 1.319 | 0.99 | |
| 155_S | 158_K | 1.316 | 0.99 | |
| 4_S | 81_A | 1.304 | 0.99 | |
| 89_L | 95_F | 1.293 | 0.99 | |
| 3_L | 100_A | 1.288 | 0.99 | |
| 104_R | 108_M | 1.272 | 0.99 | |
| 156_G | 178_M | 1.27 | 0.99 | |
| 20_H | 36_W | 1.268 | 0.99 | |
| 20_H | 54_L | 1.264 | 0.99 | |
| 106_L | 115_I | 1.22 | 0.98 | |
| 49_E | 52_E | 1.211 | 0.98 | |
| 12_N | 15_G | 1.205 | 0.98 | |
| 163_D | 173_A | 1.202 | 0.98 | |
| 63_V | 76_K | 1.201 | 0.98 | |
| 31_D | 34_F | 1.197 | 0.98 | |
| 111_D | 184_A | 1.192 | 0.98 | |
| 150_I | 175_A | 1.179 | 0.98 | |
| 52_E | 55_N | 1.179 | 0.98 | |
| 41_G | 67_D | 1.176 | 0.98 | |
| 70_I | 170_S | 1.175 | 0.98 | |
| 40_D | 48_R | 1.169 | 0.97 | |
| 46_G | 50_Y | 1.169 | 0.97 | |
| 35_E | 82_Q | 1.169 | 0.97 | |
| 65_E | 76_K | 1.159 | 0.97 | |
| 159_K | 183_Y | 1.157 | 0.97 | |
| 81_A | 154_V | 1.15 | 0.97 | |
| 2_L | 82_Q | 1.133 | 0.97 | |
| 114_M | 178_M | 1.132 | 0.97 | |
| 86_A | 154_V | 1.129 | 0.97 | |
| 109_Q | 112_N | 1.125 | 0.97 | |
| 48_R | 63_V | 1.122 | 0.97 | |
| 19_T | 89_L | 1.119 | 0.96 | |
| 87_L | 95_F | 1.112 | 0.96 | |
| 35_E | 61_R | 1.11 | 0.96 | |
| 87_L | 99_A | 1.103 | 0.96 | |
| 28_Q | 97_Q | 1.098 | 0.96 | |
| 3_L | 151_F | 1.089 | 0.96 | |
| 65_E | 72_D | 1.073 | 0.95 | |
| 84_K | 153_P | 1.072 | 0.95 | |
| 50_Y | 54_L | 1.051 | 0.94 | |
| 9_A | 91_S | 1.044 | 0.94 | |
| 49_E | 53_N | 1.044 | 0.94 | |
| 105_K | 108_M | 1.038 | 0.94 | |
| 103_V | 107_K | 1.038 | 0.94 | |
| 118_D | 187_K | 1.036 | 0.94 | |
| 4_S | 37_I | 1.034 | 0.94 | |
| 105_K | 109_Q | 1.033 | 0.94 | |
| 123_F | 127_H | 1.032 | 0.94 | |
| 21_A | 27_A | 1.027 | 0.94 | |
| 8_V | 73_A | 1.027 | 0.94 | |
| 9_A | 51_L | 1.024 | 0.93 | |
| 113_V | 184_A | 1.018 | 0.93 | |
| 74_M | 170_S | 1.01 | 0.93 | |
| 22_S | 95_F | 1.009 | 0.93 | |
| 39_V | 73_A | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2z86A | 4 | 0.9798 | 100 | 0.281 | Contact Map | 0.847 |
| 3bcvA | 2 | 0.8347 | 100 | 0.297 | Contact Map | 0.811 |
| 1qg8A | 1 | 0.9315 | 100 | 0.303 | Contact Map | 0.76 |
| 4fixA | 2 | 0.9879 | 100 | 0.316 | Contact Map | 0.717 |
| 3l7iA | 4 | 0.9758 | 100 | 0.318 | Contact Map | |
| 2d7iA | 1 | 0.9839 | 100 | 0.347 | Contact Map | 0.673 |
| 1xhbA | 1 | 0.9839 | 100 | 0.353 | Contact Map | 0.662 |
| 2ffuA | 1 | 0.9798 | 100 | 0.368 | Contact Map | 0.659 |
| 4hg6A | 1 | 0.9798 | 100 | 0.388 | Contact Map | 0.538 |
| 3ckjA | 1 | 0.9597 | 100 | 0.4 | Contact Map | 0.614 |
Sequence Conservation (Image Generated using WebLogo v3)