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OPENSEQ.org
PTNC - Mannose permease IIC component
UniProt: P69801 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10568
Length: 266 (243)
Sequences: 749
Seq/Len: 3.08
PTNC
Paralog alert: 0.85 [within 20: 0.13] - ratio of genomes with paralogs
Cluster includes: PTNC PTPC1
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
45_D 48_T 4.28 1.00
41_I 46_M 3.366 1.00
222_F 226_A 3.349 1.00
132_N 135_A 3.137 1.00
212_L 233_V 3.045 1.00
180_N 184_I 2.91 1.00
31_R 57_E 2.702 1.00
8_I 12_F 2.685 1.00
14_V 38_L 2.21 1.00
16_C 148_A 2.192 1.00
127_A 135_A 2.187 1.00
123_A 126_K 2.092 1.00
36_C 49_G 2.051 1.00
14_V 42_V 1.979 1.00
5_T 9_V 1.978 1.00
176_E 180_N 1.971 1.00
215_V 230_I 1.927 0.99
127_A 130_N 1.899 0.99
126_K 129_D 1.882 0.99
134_T 138_W 1.855 0.99
135_A 138_W 1.812 0.99
211_Y 229_V 1.76 0.99
12_F 156_V 1.736 0.99
126_K 130_N 1.735 0.99
76_L 106_G 1.716 0.99
168_Q 172_N 1.663 0.98
23_I 70_V 1.624 0.98
38_L 42_V 1.609 0.98
43_L 87_A 1.604 0.98
127_A 132_N 1.57 0.97
215_V 229_V 1.549 0.97
12_F 152_A 1.532 0.96
15_A 155_A 1.521 0.96
16_C 152_A 1.519 0.96
180_N 183_N 1.509 0.96
47_K 51_I 1.397 0.93
68_A 186_G 1.389 0.93
123_A 127_A 1.382 0.93
169_N 172_N 1.353 0.92
122_H 125_D 1.336 0.91
132_N 138_W 1.335 0.91
17_I 29_F 1.324 0.91
128_A 136_I 1.32 0.90
228_G 231_G 1.308 0.90
157_I 230_I 1.306 0.90
5_T 161_S 1.302 0.90
219_F 223_N 1.296 0.89
35_A 79_I 1.272 0.88
124_A 139_I 1.26 0.87
62_G 101_P 1.26 0.87
94_A 97_A 1.26 0.87
116_I 146_L 1.252 0.87
209_F 238_Y 1.243 0.86
6_L 10_L 1.238 0.86
163_G 182_L 1.237 0.86
219_F 222_F 1.231 0.86
165_S 168_Q 1.228 0.86
98_L 102_L 1.228 0.86
166_E 170_M 1.226 0.85
10_L 42_V 1.222 0.85
93_G 172_N 1.211 0.85
55_T 59_I 1.208 0.84
33_L 37_T 1.192 0.83
7_Q 11_V 1.19 0.83
11_V 39_V 1.181 0.82
11_V 43_L 1.176 0.82
72_P 103_A 1.159 0.81
37_T 46_M 1.157 0.81
217_A 227_L 1.152 0.80
185_A 189_I 1.152 0.80
109_L 154_P 1.148 0.80
184_I 187_G 1.146 0.80
85_V 95_G 1.145 0.80
77_A 83_I 1.141 0.79
7_Q 10_L 1.14 0.79
148_A 152_A 1.131 0.78
13_I 41_I 1.131 0.78
17_I 237_L 1.121 0.78
77_A 103_A 1.121 0.78
207_M 211_Y 1.121 0.78
156_V 160_L 1.113 0.77
133_L 137_S 1.108 0.76
232_T 236_V 1.094 0.75
34_I 37_T 1.092 0.75
58_M 198_I 1.085 0.74
107_Q 196_M 1.083 0.74
135_A 139_I 1.083 0.74
181_G 185_A 1.08 0.74
7_Q 42_V 1.074 0.73
166_E 169_N 1.073 0.73
128_A 132_N 1.072 0.73
217_A 230_I 1.068 0.73
14_V 35_A 1.066 0.72
49_G 53_G 1.051 0.71
168_Q 176_E 1.05 0.71
101_P 105_A 1.049 0.71
18_A 141_V 1.044 0.70
48_T 52_I 1.039 0.70
240_Q 243_P 1.035 0.69
154_P 157_I 1.034 0.69
107_Q 171_L 1.032 0.69
57_E 159_A 1.025 0.68
7_Q 87_A 1.022 0.68
159_A 163_G 1.012 0.67
11_V 230_I 1.008 0.66
105_A 171_L 1.006 0.66
34_I 38_L 1.003 0.66
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2xzeQ20.101516.40.966Contact Map
4kjrA20.60538.70.97Contact Map0.421
4ltoA40.45117.30.971Contact Map0.484
3cx5I20.19924.60.974Contact Map0.56
4nawD40.06024.50.974Contact Map
2i68A20.43613.70.975Contact Map0.01
3m9dG60.12783.10.976Contact Map
2affB10.10532.70.977Contact Map
4kppA20.53762.70.977Contact Map0.271
2f93B10.33832.50.977Contact Map0.119
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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