| UniProt: | P69423 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11479 | ||
| Length: | 258 (238) | ||
| Sequences: | 1570 | ||
| Seq/Len: | 6.60 |
| TATC
Paralog alert: 0.06 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 193_R | 227_E | 3.882 | 1.00 | |
| 26_A | 86_V | 3.675 | 1.00 | |
| 179_C | 233_S | 3.66 | 1.00 | |
| 18_K | 22_N | 3.092 | 1.00 | |
| 190_R | 234_R | 2.789 | 1.00 | |
| 15_E | 19_R | 2.752 | 1.00 | |
| 201_F | 219_A | 2.484 | 1.00 | |
| 22_N | 86_V | 2.3 | 1.00 | |
| 196_V | 226_F | 2.28 | 1.00 | |
| 89_Y | 93_A | 2.21 | 1.00 | |
| 20_L | 24_I | 2.147 | 1.00 | |
| 79_S | 83_S | 2.061 | 1.00 | |
| 141_A | 147_V | 2.026 | 1.00 | |
| 186_P | 233_S | 1.985 | 1.00 | |
| 31_F | 79_S | 1.981 | 1.00 | |
| 197_L | 223_Y | 1.975 | 1.00 | |
| 37_F | 40_D | 1.919 | 1.00 | |
| 123_A | 127_F | 1.913 | 1.00 | |
| 186_P | 237_V | 1.903 | 1.00 | |
| 175_I | 189_L | 1.831 | 1.00 | |
| 118_F | 166_G | 1.819 | 1.00 | |
| 226_F | 230_V | 1.814 | 1.00 | |
| 23_C | 87_I | 1.752 | 1.00 | |
| 62_T | 150_D | 1.75 | 1.00 | |
| 19_R | 90_Q | 1.704 | 1.00 | |
| 8_P | 11_T | 1.653 | 1.00 | |
| 26_A | 83_S | 1.644 | 1.00 | |
| 99_L | 103_E | 1.636 | 1.00 | |
| 22_N | 90_Q | 1.635 | 1.00 | |
| 58_T | 146_Q | 1.614 | 1.00 | |
| 34_L | 78_V | 1.61 | 1.00 | |
| 210_P | 215_Q | 1.603 | 1.00 | |
| 111_L | 115_S | 1.602 | 1.00 | |
| 195_Y | 199_G | 1.598 | 1.00 | |
| 66_S | 150_D | 1.595 | 1.00 | |
| 64_V | 134_F | 1.586 | 1.00 | |
| 32_L | 36_Y | 1.58 | 1.00 | |
| 185_S | 188_D | 1.566 | 0.99 | |
| 19_R | 93_A | 1.55 | 0.99 | |
| 187_E | 191_K | 1.528 | 0.99 | |
| 21_L | 25_I | 1.503 | 0.99 | |
| 201_F | 215_Q | 1.5 | 0.99 | |
| 188_D | 192_K | 1.493 | 0.99 | |
| 190_R | 193_R | 1.489 | 0.99 | |
| 114_S | 170_E | 1.476 | 0.99 | |
| 178_L | 183_I | 1.461 | 0.99 | |
| 207_L | 218_L | 1.455 | 0.99 | |
| 27_V | 87_I | 1.441 | 0.99 | |
| 61_A | 67_P | 1.428 | 0.99 | |
| 192_K | 195_Y | 1.428 | 0.99 | |
| 30_I | 82_L | 1.425 | 0.99 | |
| 190_R | 227_E | 1.424 | 0.99 | |
| 179_C | 186_P | 1.404 | 0.99 | |
| 212_V | 215_Q | 1.394 | 0.99 | |
| 64_V | 157_F | 1.393 | 0.99 | |
| 27_V | 83_S | 1.382 | 0.98 | |
| 48_P | 154_Y | 1.343 | 0.98 | |
| 30_I | 79_S | 1.342 | 0.98 | |
| 27_V | 76_F | 1.334 | 0.98 | |
| 47_A | 51_K | 1.315 | 0.98 | |
| 77_M | 81_I | 1.308 | 0.98 | |
| 200_A | 222_M | 1.306 | 0.97 | |
| 41_I | 78_V | 1.3 | 0.97 | |
| 198_V | 202_V | 1.288 | 0.97 | |
| 150_D | 153_S | 1.277 | 0.97 | |
| 83_S | 87_I | 1.271 | 0.97 | |
| 128_V | 217_L | 1.264 | 0.97 | |
| 184_T | 189_L | 1.259 | 0.97 | |
| 199_G | 202_V | 1.254 | 0.97 | |
| 186_P | 190_R | 1.249 | 0.96 | |
| 84_A | 88_L | 1.243 | 0.96 | |
| 61_A | 151_I | 1.243 | 0.96 | |
| 176_V | 236_Y | 1.23 | 0.96 | |
| 23_C | 83_S | 1.22 | 0.96 | |
| 12_H | 16_L | 1.202 | 0.95 | |
| 65_A | 137_L | 1.193 | 0.95 | |
| 227_E | 231_F | 1.181 | 0.95 | |
| 187_E | 190_R | 1.165 | 0.94 | |
| 192_K | 196_V | 1.163 | 0.94 | |
| 44_L | 127_F | 1.161 | 0.94 | |
| 98_A | 103_E | 1.16 | 0.94 | |
| 61_A | 145_V | 1.156 | 0.94 | |
| 35_V | 71_P | 1.154 | 0.94 | |
| 145_V | 151_I | 1.152 | 0.94 | |
| 193_R | 197_L | 1.147 | 0.94 | |
| 71_P | 140_T | 1.142 | 0.93 | |
| 19_R | 98_A | 1.141 | 0.93 | |
| 171_V | 200_A | 1.14 | 0.93 | |
| 203_V | 207_L | 1.121 | 0.93 | |
| 60_I | 148_S | 1.12 | 0.92 | |
| 236_Y | 240_G | 1.111 | 0.92 | |
| 28_I | 32_L | 1.096 | 0.91 | |
| 186_P | 230_V | 1.089 | 0.91 | |
| 112_V | 116_L | 1.073 | 0.90 | |
| 116_L | 120_I | 1.071 | 0.90 | |
| 141_A | 157_F | 1.065 | 0.90 | |
| 171_V | 222_M | 1.059 | 0.89 | |
| 196_V | 200_A | 1.057 | 0.89 | |
| 119_Y | 123_A | 1.055 | 0.89 | |
| 80_L | 84_A | 1.049 | 0.89 | |
| 12_H | 103_E | 1.048 | 0.89 | |
| 12_H | 15_E | 1.045 | 0.89 | |
| 7_Q | 74_L | 1.042 | 0.88 | |
| 62_T | 148_S | 1.037 | 0.88 | |
| 204_G | 222_M | 1.036 | 0.88 | |
| 30_I | 83_S | 1.034 | 0.88 | |
| 84_A | 111_L | 1.031 | 0.88 | |
| 30_I | 34_L | 1.029 | 0.88 | |
| 122_M | 162_F | 1.007 | 0.86 | |
| 22_N | 89_Y | 1.006 | 0.86 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4httA | 2 | 0.9767 | 100 | 0.132 | Contact Map | 0.485 |
| 4b4aA | 1 | 0.9574 | 100 | 0.136 | Contact Map | 0.58 |
| 2m7xA | 1 | 0.1124 | 14.2 | 0.961 | Contact Map | 0.003 |
| 2l0eA | 1 | 0.1279 | 6.4 | 0.967 | Contact Map | 0.425 |
| 2kncA | 1 | 0.2093 | 4.6 | 0.969 | Contact Map | 0.255 |
| 2rddB | 1 | 0.1434 | 4.4 | 0.97 | Contact Map | 0.346 |
| 1sv0A | 2 | 0.1124 | 3.8 | 0.97 | Contact Map | 0.986 |
| 3ggzE | 4 | 0.0698 | 3.5 | 0.971 | Contact Map | 1 |
| 1pw4A | 1 | 0.7442 | 3.4 | 0.971 | Contact Map | 0.155 |
| 1jzpA | 1 | 0.0388 | 3.2 | 0.971 | Contact Map |
Sequence Conservation (Image Generated using WebLogo v3)