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OPENSEQ.org

YQFA - UPF0073 inner membrane protein YqfA
UniProt: P67153 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13077
Length: 219 (207)
Sequences: 1169
Seq/Len: 5.65

YQFA
Paralog alert: 0.07 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
65_F 205_S 3.79 1.00
177_V 207_C 2.794 1.00
102_F 211_A 2.691 1.00
146_L 182_V 2.499 1.00
150_W 179_S 2.47 1.00
165_A 169_T 2.462 1.00
16_E 19_N 2.433 1.00
113_R 117_I 2.379 1.00
199_G 203_G 2.331 1.00
117_I 121_S 2.318 1.00
34_L 58_G 2.227 1.00
146_L 179_S 2.172 1.00
130_K 141_S 2.131 1.00
113_R 116_M 2.035 1.00
60_S 97_G 2.03 1.00
169_T 173_V 1.995 1.00
26_G 202_L 1.916 1.00
177_V 203_G 1.901 1.00
27_L 66_L 1.895 1.00
185_Y 188_K 1.871 1.00
114_G 118_V 1.856 1.00
60_S 93_L 1.846 1.00
55_S 59_G 1.776 1.00
170_L 210_L 1.759 1.00
177_V 204_G 1.732 1.00
61_M 205_S 1.719 1.00
82_W 86_F 1.706 1.00
27_L 62_I 1.693 1.00
88_H 185_Y 1.652 1.00
51_I 55_S 1.647 1.00
66_L 70_L 1.63 0.99
170_L 207_C 1.622 0.99
105_V 216_I 1.59 0.99
67_A 86_F 1.571 0.99
96_A 123_A 1.541 0.99
61_M 94_L 1.505 0.99
109_S 112_A 1.473 0.99
48_A 52_T 1.467 0.99
122_L 148_M 1.46 0.99
93_L 127_I 1.422 0.98
28_V 32_V 1.415 0.98
13_L 17_I 1.414 0.98
187_C 190_I 1.402 0.98
206_V 210_L 1.402 0.98
18_A 195_A 1.402 0.98
33_G 209_F 1.39 0.98
35_V 39_V 1.388 0.98
182_V 197_W 1.367 0.98
122_L 144_T 1.354 0.97
24_G 69_T 1.351 0.97
157_Y 161_V 1.337 0.97
128_L 132_T 1.334 0.97
14_A 17_I 1.322 0.97
72_H 194_H 1.312 0.97
108_D 112_A 1.29 0.96
167_S 215_Y 1.275 0.96
173_V 177_V 1.275 0.96
74_I 83_L 1.271 0.96
49_T 108_D 1.268 0.96
90_A 93_L 1.268 0.96
71_Y 84_K 1.258 0.95
60_S 94_L 1.242 0.95
20_S 73_A 1.239 0.95
163_L 168_V 1.227 0.95
111_L 114_G 1.224 0.94
110_P 114_G 1.219 0.94
168_V 172_A 1.216 0.94
31_I 62_I 1.212 0.94
94_L 98_T 1.21 0.94
172_A 176_V 1.201 0.94
115_L 155_V 1.178 0.93
111_L 154_V 1.16 0.92
12_S 15_E 1.148 0.92
62_I 66_L 1.145 0.91
173_V 207_C 1.144 0.91
56_L 100_T 1.143 0.91
38_L 55_S 1.143 0.91
210_L 213_Y 1.141 0.91
190_I 193_N 1.137 0.91
155_V 158_E 1.13 0.91
15_E 195_A 1.123 0.90
122_L 151_L 1.117 0.90
15_E 19_N 1.115 0.90
118_V 151_L 1.104 0.89
24_G 70_L 1.103 0.89
133_I 137_F 1.099 0.89
19_N 22_S 1.094 0.89
52_T 55_S 1.086 0.88
209_F 213_Y 1.085 0.88
210_L 214_L 1.082 0.88
109_S 113_R 1.076 0.88
119_I 123_A 1.073 0.88
19_N 194_H 1.069 0.87
138_K 193_N 1.068 0.87
119_I 148_M 1.067 0.87
17_I 21_V 1.057 0.86
96_A 120_W 1.05 0.86
14_A 18_A 1.05 0.86
197_W 201_V 1.049 0.86
57_Y 61_M 1.027 0.84
143_V 147_A 1.022 0.84
15_E 18_A 1.019 0.84
40_Q 43_D 1.018 0.84
16_E 194_H 1.018 0.84
40_Q 213_Y 1.012 0.83
53_S 104_L 1.01 0.83
103_L 115_L 1 0.82
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
1v54K20.15532.10.971Contact Map0.458
3ddlA20.31051.80.972Contact Map0.233
2ls2A10.11421.60.973Contact Map0.22
2wswA10.33791.50.973Contact Map0.213
3rlfF10.39731.10.975Contact Map0.149
1n13B60.182610.976Contact Map0
3am6A40.278510.976Contact Map0.385
4fbzA10.27410.976Contact Map0.14
3s90C20.14160.90.977Contact Map0.827
1rklA10.15980.80.977Contact Map0.546

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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