| UniProt: | P64557 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13063 | ||
| Length: | 259 (247) | ||
| Sequences: | 2624 | ||
| Seq/Len: | 10.62 |
| YGFM
Paralog alert: 0.56 [within 20: 0.15] - ratio of genomes with paralogs Cluster includes: XDHB YAGS YGFM |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 201_R | 206_E | 4.086 | 1.00 | |
| 126_E | 134_T | 3.389 | 1.00 | |
| 128_V | 153_I | 3.381 | 1.00 | |
| 65_R | 151_E | 3.154 | 1.00 | |
| 133_E | 147_R | 3.079 | 1.00 | |
| 128_V | 151_E | 3.06 | 1.00 | |
| 129_F | 135_L | 2.9 | 1.00 | |
| 56_W | 70_S | 2.871 | 1.00 | |
| 108_A | 149_L | 2.748 | 1.00 | |
| 70_S | 75_L | 2.567 | 1.00 | |
| 136_S | 139_D | 2.557 | 1.00 | |
| 127_L | 149_L | 2.431 | 1.00 | |
| 134_T | 153_I | 2.312 | 1.00 | |
| 187_G | 211_E | 2.209 | 1.00 | |
| 55_D | 74_P | 1.994 | 1.00 | |
| 7_R | 51_D | 1.987 | 1.00 | |
| 16_E | 20_R | 1.977 | 1.00 | |
| 124_D | 138_E | 1.944 | 1.00 | |
| 115_V | 165_K | 1.914 | 1.00 | |
| 10_S | 13_Q | 1.905 | 1.00 | |
| 71_R | 74_P | 1.826 | 1.00 | |
| 63_A | 153_I | 1.802 | 1.00 | |
| 49_L | 69_M | 1.777 | 1.00 | |
| 166_I | 239_I | 1.762 | 1.00 | |
| 27_W | 148_L | 1.76 | 1.00 | |
| 135_L | 142_A | 1.759 | 1.00 | |
| 66_I | 75_L | 1.745 | 1.00 | |
| 5_F | 48_S | 1.708 | 1.00 | |
| 104_G | 149_L | 1.697 | 1.00 | |
| 129_F | 143_C | 1.696 | 1.00 | |
| 127_L | 137_I | 1.692 | 1.00 | |
| 128_V | 134_T | 1.686 | 1.00 | |
| 181_A | 187_G | 1.635 | 1.00 | |
| 130_G | 150_T | 1.633 | 1.00 | |
| 192_L | 202_L | 1.599 | 1.00 | |
| 27_W | 49_L | 1.584 | 1.00 | |
| 64_L | 81_I | 1.559 | 1.00 | |
| 18_K | 27_W | 1.55 | 1.00 | |
| 6_F | 17_L | 1.538 | 1.00 | |
| 126_E | 153_I | 1.533 | 1.00 | |
| 15_L | 131_N | 1.528 | 1.00 | |
| 18_K | 47_I | 1.457 | 1.00 | |
| 220_A | 241_G | 1.452 | 1.00 | |
| 192_L | 240_T | 1.446 | 1.00 | |
| 72_L | 101_S | 1.438 | 1.00 | |
| 72_L | 116_L | 1.436 | 1.00 | |
| 164_R | 250_D | 1.435 | 1.00 | |
| 6_F | 45_I | 1.434 | 1.00 | |
| 73_Q | 99_N | 1.433 | 1.00 | |
| 202_L | 205_V | 1.431 | 1.00 | |
| 138_E | 203_H | 1.424 | 1.00 | |
| 177_T | 193_D | 1.419 | 1.00 | |
| 204_D | 207_K | 1.419 | 1.00 | |
| 180_V | 247_L | 1.413 | 1.00 | |
| 29_A | 69_M | 1.401 | 0.99 | |
| 204_D | 222_A | 1.381 | 0.99 | |
| 73_Q | 77_D | 1.379 | 0.99 | |
| 14_A | 148_L | 1.377 | 0.99 | |
| 29_A | 102_T | 1.366 | 0.99 | |
| 59_W | 156_D | 1.365 | 0.99 | |
| 25_A | 47_I | 1.361 | 0.99 | |
| 126_E | 136_S | 1.357 | 0.99 | |
| 65_R | 153_I | 1.345 | 0.99 | |
| 8_P | 13_Q | 1.339 | 0.99 | |
| 203_H | 207_K | 1.339 | 0.99 | |
| 9_D | 13_Q | 1.321 | 0.99 | |
| 7_R | 48_S | 1.32 | 0.99 | |
| 247_L | 251_C | 1.311 | 0.99 | |
| 114_S | 117_L | 1.303 | 0.99 | |
| 117_L | 141_L | 1.289 | 0.99 | |
| 118_P | 193_D | 1.266 | 0.99 | |
| 72_L | 92_V | 1.258 | 0.99 | |
| 11_V | 53_E | 1.257 | 0.99 | |
| 164_R | 246_D | 1.254 | 0.99 | |
| 32_S | 106_E | 1.248 | 0.99 | |
| 205_V | 222_A | 1.248 | 0.99 | |
| 12_E | 130_G | 1.248 | 0.99 | |
| 68_A | 104_G | 1.246 | 0.98 | |
| 11_V | 148_L | 1.245 | 0.98 | |
| 15_L | 132_G | 1.245 | 0.98 | |
| 8_P | 49_L | 1.238 | 0.98 | |
| 56_W | 151_E | 1.229 | 0.98 | |
| 58_D | 65_R | 1.227 | 0.98 | |
| 192_L | 195_V | 1.214 | 0.98 | |
| 188_M | 211_E | 1.205 | 0.98 | |
| 11_V | 15_L | 1.203 | 0.98 | |
| 180_V | 190_I | 1.201 | 0.98 | |
| 33_K | 109_A | 1.201 | 0.98 | |
| 137_I | 141_L | 1.197 | 0.98 | |
| 219_V | 244_V | 1.171 | 0.98 | |
| 62_G | 156_D | 1.159 | 0.97 | |
| 188_M | 210_L | 1.15 | 0.97 | |
| 55_D | 71_R | 1.146 | 0.97 | |
| 57_V | 78_A | 1.14 | 0.97 | |
| 60_D | 65_R | 1.137 | 0.97 | |
| 17_L | 47_I | 1.133 | 0.97 | |
| 33_K | 111_Q | 1.122 | 0.97 | |
| 107_I | 120_L | 1.118 | 0.96 | |
| 107_I | 152_I | 1.117 | 0.96 | |
| 55_D | 69_M | 1.112 | 0.96 | |
| 63_A | 156_D | 1.107 | 0.96 | |
| 238_Y | 242_V | 1.105 | 0.96 | |
| 50_Q | 71_R | 1.099 | 0.96 | |
| 4_Q | 45_I | 1.098 | 0.96 | |
| 85_L | 119_V | 1.093 | 0.96 | |
| 166_I | 243_L | 1.092 | 0.96 | |
| 163_T | 177_T | 1.09 | 0.96 | |
| 27_W | 47_I | 1.089 | 0.96 | |
| 75_L | 103_I | 1.087 | 0.96 | |
| 21_Y | 45_I | 1.079 | 0.95 | |
| 238_Y | 241_G | 1.076 | 0.95 | |
| 92_V | 101_S | 1.073 | 0.95 | |
| 191_A | 201_R | 1.067 | 0.95 | |
| 24_E | 44_K | 1.057 | 0.95 | |
| 120_L | 127_L | 1.057 | 0.95 | |
| 14_A | 52_L | 1.054 | 0.95 | |
| 28_F | 31_G | 1.037 | 0.94 | |
| 88_A | 119_V | 1.024 | 0.93 | |
| 129_F | 147_R | 1.017 | 0.93 | |
| 65_R | 128_V | 1.012 | 0.93 | |
| 174_T | 177_T | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1rm6B | 2 | 0.9653 | 100 | 0.117 | Contact Map | 0.745 |
| 1n62C | 2 | 0.9884 | 100 | 0.121 | Contact Map | 0.83 |
| 1t3qC | 2 | 0.9846 | 100 | 0.126 | Contact Map | 0.784 |
| 3zyvA | 4 | 0.9923 | 100 | 0.143 | Contact Map | 0.772 |
| 3hrdC | 2 | 0.9961 | 100 | 0.152 | Contact Map | 0.891 |
| 1ffvC | 2 | 0.9807 | 100 | 0.155 | Contact Map | 0.807 |
| 2w3sA | 4 | 0.9807 | 100 | 0.157 | Contact Map | 0.764 |
| 3uncA | 2 | 0.9923 | 100 | 0.178 | Contact Map | 0.773 |
| 3nvzB | 2 | 0.9807 | 100 | 0.187 | Contact Map | 0.76 |
| 3tx1A | 1 | 0.9112 | 97 | 0.884 | Contact Map | 0.578 |
Sequence Conservation (Image Generated using WebLogo v3)