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OPENSEQ.org

RL24 - 50S ribosomal protein L24
UniProt: P60624 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10884
Length: 104 (103)
Sequences: 1224
Seq/Len: 11.88

RL24
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
43_K 60_E 3.978 1.00
34_V 70_V 3.89 1.00
5_I 25_V 3.269 1.00
12_I 22_R 3.123 1.00
76_A 101_E 2.561 1.00
24_K 37_E 2.495 1.00
13_V 39_I 2.467 1.00
77_T 99_N 2.324 1.00
96_F 99_N 2.32 1.00
43_K 58_I 2.231 1.00
32_G 66_Q 2.147 1.00
74_N 99_N 2.135 1.00
86_R 95_F 2.107 1.00
18_D 21_K 1.998 1.00
33_K 64_A 1.97 1.00
42_V 63_A 1.947 1.00
87_F 92_K 1.942 1.00
74_N 77_T 1.933 1.00
74_N 96_F 1.903 1.00
81_D 96_F 1.898 1.00
10_E 22_R 1.894 1.00
66_Q 69_N 1.775 1.00
14_L 71_A 1.762 1.00
15_T 69_N 1.73 1.00
84_G 97_K 1.695 1.00
72_I 103_I 1.592 1.00
72_I 83_V 1.572 1.00
32_G 67_V 1.562 1.00
77_T 96_F 1.547 1.00
84_G 95_F 1.475 1.00
10_E 24_K 1.452 1.00
34_V 67_V 1.37 0.99
49_V 53_N 1.336 0.99
93_V 102_T 1.311 0.99
49_V 54_Q 1.311 0.99
41_L 60_E 1.307 0.99
12_I 80_A 1.251 0.99
73_F 78_G 1.242 0.98
46_Q 59_V 1.202 0.98
21_K 39_I 1.195 0.98
85_F 92_K 1.152 0.97
33_K 66_Q 1.149 0.97
26_K 37_E 1.144 0.97
45_H 58_I 1.13 0.97
35_I 61_K 1.111 0.96
48_P 56_G 1.102 0.96
28_V 67_V 1.034 0.94
27_N 35_I 1.028 0.94
18_D 39_I 1.003 0.93
8_D 24_K 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3bboW10.99041000.072Contact Map0.297
4kixU10.99041000.083Contact Map0.846
3v2dY10.99041000.094Contact Map0.942
2zjrR10.99041000.103Contact Map0.393
3j3wU10.97121000.116Contact Map0.088
2ftcN10.90381000.162Contact Map0.095
4a17S10.836599.90.414Contact Map0.614
1vq8T10.769299.90.425Contact Map0.597
3j3bY10.855899.90.426Contact Map0.457
3iz5Y10.855899.90.429Contact Map0.605

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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