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FLII - Flagellum-specific ATP synthase
UniProt: P52612 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG20266
Length: 457 (420)
Sequences: 3824
Seq/Len: 9.10
FLII
Paralog alert: 0.65 [within 20: 0.38] - ratio of genomes with paralogs
Cluster includes: ATPA ATPB FLII
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
122_D 126_K 8.101 1.00
354_S 367_D 3.921 1.00
41_A 79_L 3.768 1.00
115_A 137_T 3.627 1.00
174_R 266_H 3.512 1.00
382_E 386_A 3.488 1.00
207_G 253_A 3.483 1.00
441_D 444_A 3.367 1.00
114_P 263_R 2.981 1.00
52_C 79_L 2.831 1.00
140_G 144_T 2.831 1.00
131_L 224_L 2.756 1.00
257_A 322_I 2.702 1.00
106_S 109_Q 2.585 1.00
275_T 279_M 2.488 1.00
50_A 96_A 2.478 1.00
221_E 225_G 2.464 1.00
121_L 256_I 2.45 1.00
165_P 366_I 2.437 1.00
360_A 429_E 2.433 1.00
221_E 224_L 2.391 1.00
109_Q 139_T 2.385 1.00
383_Q 450_E 2.345 1.00
67_S 79_L 2.328 1.00
46_L 69_V 2.328 1.00
390_T 393_Q 2.299 1.00
157_H 174_R 2.271 1.00
114_P 265_Q 2.269 1.00
391_F 428_L 2.267 1.00
119_R 129_D 2.249 1.00
233_V 256_I 2.231 1.00
335_Q 352_V 2.219 1.00
115_A 135_D 2.167 1.00
46_L 52_C 2.156 1.00
389_R 392_K 2.106 1.00
190_V 436_I 2.105 1.00
362_H 429_E 2.078 1.00
254_T 322_I 2.055 1.00
172_V 351_I 2.039 1.00
31_L 88_V 2.007 1.00
153_T 156_E 2 1.00
381_S 442_W 1.997 1.00
227_E 230_A 1.997 1.00
168_A 445_S 1.991 1.00
53_V 95_Y 1.972 1.00
220_I 234_V 1.965 1.00
224_L 229_R 1.962 1.00
235_I 256_I 1.96 1.00
52_C 94_V 1.922 1.00
205_V 257_A 1.866 1.00
31_L 92_A 1.832 1.00
159_L 203_V 1.808 1.00
169_L 391_F 1.798 1.00
387_R 450_E 1.791 1.00
328_V 343_A 1.789 1.00
30_R 93_R 1.788 1.00
110_L 256_I 1.782 1.00
41_A 94_V 1.744 1.00
121_L 134_P 1.742 1.00
115_A 136_T 1.728 1.00
97_K 105_Q 1.716 1.00
39_L 67_S 1.706 1.00
254_T 326_Y 1.683 1.00
205_V 256_I 1.681 1.00
380_I 385_Y 1.679 1.00
114_P 259_D 1.677 1.00
55_E 93_R 1.674 1.00
172_V 325_F 1.659 1.00
399_Q 402_R 1.646 1.00
151_Q 316_I 1.634 1.00
163_V 166_I 1.631 1.00
170_L 366_I 1.617 1.00
157_H 314_N 1.601 1.00
33_R 40_E 1.564 1.00
123_G 128_L 1.536 1.00
254_T 312_A 1.531 1.00
28_Y 93_R 1.52 1.00
413_G 419_D 1.514 1.00
138_E 259_D 1.512 1.00
213_G 238_P 1.494 1.00
335_Q 370_A 1.491 1.00
160_D 442_W 1.481 1.00
183_G 186_V 1.47 1.00
259_D 263_R 1.466 1.00
127_P 132_P 1.461 1.00
356_R 359_E 1.452 1.00
121_L 235_I 1.452 1.00
56_R 96_A 1.438 0.99
156_E 319_G 1.435 0.99
140_G 255_R 1.434 0.99
217_K 221_E 1.428 0.99
435_G 438_E 1.416 0.99
163_V 191_L 1.412 0.99
444_A 448_G 1.404 0.99
357_L 362_H 1.403 0.99
128_L 236_A 1.402 0.99
447_Q 451_R 1.402 0.99
423_A 426_P 1.399 0.99
136_T 139_T 1.398 0.99
40_E 76_R 1.39 0.99
110_L 252_Y 1.39 0.99
224_L 230_A 1.378 0.99
397_S 400_R 1.378 0.99
116_L 256_I 1.366 0.99
46_L 51_T 1.355 0.99
264_G 317_S 1.35 0.99
390_T 394_L 1.346 0.99
81_P 85_V 1.34 0.99
226_A 230_A 1.339 0.99
267_V 322_I 1.335 0.99
65_V 83_E 1.331 0.99
220_I 224_L 1.328 0.99
144_T 262_D 1.323 0.99
164_R 440_A 1.32 0.99
123_G 252_Y 1.314 0.99
160_D 167_N 1.3 0.99
362_H 433_Q 1.295 0.99
197_R 437_F 1.282 0.99
258_E 311_R 1.279 0.99
190_V 437_F 1.265 0.98
155_I 173_G 1.262 0.98
32_T 42_T 1.256 0.98
48_L 52_C 1.255 0.98
171_T 376_M 1.254 0.98
193_G 236_A 1.253 0.98
148_N 152_R 1.251 0.98
179_G 347_L 1.242 0.98
140_G 259_D 1.242 0.98
157_H 266_H 1.236 0.98
266_H 321_S 1.236 0.98
207_G 271_M 1.235 0.98
42_T 76_R 1.233 0.98
32_T 76_R 1.23 0.98
122_D 241_V 1.228 0.98
52_C 67_S 1.225 0.98
49_G 52_C 1.214 0.98
141_A 144_T 1.207 0.98
111_P 136_T 1.206 0.98
223_I 228_G 1.201 0.98
114_P 203_V 1.196 0.97
352_V 355_R 1.189 0.97
173_G 375_A 1.18 0.97
108_K 142_L 1.175 0.97
54_I 67_S 1.169 0.97
261_R 315_G 1.163 0.97
202_D 265_Q 1.156 0.97
402_R 406_S 1.147 0.96
209_I 249_G 1.147 0.96
357_L 374_R 1.141 0.96
66_E 126_K 1.14 0.96
416_P 420_K 1.137 0.96
96_A 105_Q 1.132 0.96
30_R 42_T 1.126 0.96
387_R 453_F 1.125 0.96
246_R 283_E 1.121 0.96
390_T 420_K 1.118 0.96
354_S 370_A 1.117 0.96
207_G 269_L 1.115 0.96
387_R 446_L 1.11 0.96
208_L 216_V 1.108 0.95
233_V 260_F 1.092 0.95
135_D 138_E 1.089 0.95
285_A 293_A 1.087 0.95
230_A 233_V 1.084 0.95
383_Q 387_R 1.082 0.95
47_P 50_A 1.081 0.95
203_V 260_F 1.08 0.95
48_L 51_T 1.077 0.94
377_T 392_K 1.075 0.94
170_L 351_I 1.075 0.94
168_A 431_Y 1.074 0.94
114_P 137_T 1.066 0.94
225_G 228_G 1.066 0.94
183_G 333_D 1.056 0.94
65_V 87_G 1.055 0.94
116_L 233_V 1.051 0.93
367_D 370_A 1.048 0.93
43_G 46_L 1.047 0.93
197_R 203_V 1.045 0.93
384_H 446_L 1.039 0.93
204_I 265_Q 1.036 0.93
201_A 231_R 1.033 0.93
376_M 388_V 1.033 0.93
117_L 233_V 1.032 0.93
89_L 92_A 1.03 0.93
361_G 389_R 1.026 0.92
413_G 417_M 1.026 0.92
333_D 355_R 1.022 0.92
53_V 64_E 1.02 0.92
349_G 374_R 1.016 0.92
50_A 105_Q 1.014 0.92
419_D 423_A 1.012 0.92
305_L 342_S 1.012 0.92
97_K 106_S 1.012 0.92
55_E 95_Y 1.008 0.91
423_A 427_Q 1.007 0.91
430_G 433_Q 1.003 0.91
119_R 132_P 1 0.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3oaaA120.95621000.129Contact Map0.703
2qe7A30.96281000.129Contact Map0.722
2r9vA10.9651000.147Contact Map0.73
1fx0A10.95621000.149Contact Map0.662
2c61A20.93871000.151Contact Map0.611
3vr4D30.93441000.152Contact Map0.67
2ck3A30.96281000.154Contact Map0.761
3gqbB20.92341000.155Contact Map0.613
3mfyA10.90811000.174Contact Map0.608
1fx0B10.95841000.184Contact Map0.618
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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