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OPENSEQ.org

YHBQ - UPF0213 protein YhbQ
UniProt: P45472 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12786
Length: 100 (87)
Sequences: 1338
Seq/Len: 15.38

YHBQ
Paralog alert: 0.07 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
52_A 63_A 3.023 1.00
26_R 30_Q 2.997 1.00
18_T 67_V 2.554 1.00
65_Y 69_Q 2.259 1.00
8_L 18_T 2.159 1.00
4_W 20_I 2.113 1.00
56_D 59_L 2.102 1.00
20_I 61_L 2.064 1.00
24_V 51_S 1.953 1.00
63_A 66_R 1.927 1.00
15_K 39_A 1.892 1.00
6_L 67_V 1.846 1.00
29_Q 33_S 1.797 1.00
9_I 28_Y 1.783 1.00
57_R 61_L 1.728 1.00
72_K 76_E 1.724 1.00
58_S 62_R 1.667 1.00
70_L 74_Q 1.653 1.00
28_Y 32_Q 1.635 1.00
10_R 47_T 1.617 1.00
13_D 43_K 1.577 1.00
37_A 41_R 1.562 1.00
71_T 74_Q 1.49 1.00
10_R 14_N 1.484 1.00
54_V 63_A 1.472 1.00
4_W 57_R 1.434 1.00
10_R 49_V 1.313 0.99
16_L 76_E 1.269 0.99
63_A 78_L 1.26 0.99
50_F 63_A 1.243 0.98
10_R 76_E 1.231 0.98
11_T 39_A 1.226 0.98
32_Q 44_G 1.208 0.98
22_T 26_R 1.196 0.98
24_V 48_L 1.154 0.97
73_R 77_R 1.149 0.97
21_T 24_V 1.129 0.97
77_R 81_E 1.121 0.97
40_L 45_E 1.113 0.96
32_Q 46_L 1.109 0.96
20_I 57_R 1.095 0.96
8_L 67_V 1.085 0.96
30_Q 35_K 1.066 0.95
58_S 61_L 1.042 0.94
6_L 18_T 1.033 0.94
9_I 45_E 1.018 0.93
74_Q 77_R 1.01 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1zg2A10.961000.091Contact Map0.527
1ywlA10.911000.155Contact Map0.43
1mk0A10.8497.90.735Contact Map0.468
1yd0A10.8497.20.769Contact Map0.517
1yd6A40.8496.90.776Contact Map0.758
2wshA40.81610.879Contact Map0.383
3o6qA20.934.10.933Contact Map0.263
2ra8A10.873.90.933Contact Map0.164
3h4zA30.373.20.936Contact Map0.269
4gbsA20.42.30.941Contact Map0.324

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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