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YRAI - Uncharacterized fimbrial chaperone YraI
UniProt: P42914 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12774
Length: 231 (210)
Sequences: 1350
Seq/Len: 6.43

YRAI
Paralog alert: 0.90 [within 20: 0.52] - ratio of genomes with paralogs
Cluster includes: ECPD ELFD FIMC SFMC YBGP YCBF YEHC YFCS YHCA YQIH YRAI
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
98_L 106_F 2.875 1.00
28_L 135_I 2.871 1.00
175_V 192_Y 2.861 1.00
173_Y 194_A 2.783 1.00
194_A 197_E 2.733 1.00
105_L 192_Y 2.723 1.00
138_F 192_Y 2.564 1.00
102_K 196_G 2.457 1.00
36_D 39_R 2.445 1.00
167_Y 198_H 2.366 1.00
156_E 167_Y 2.263 1.00
61_V 137_M 2.208 1.00
33_V 108_I 2.167 1.00
60_W 109_N 2.15 1.00
55_Y 112_A 2.132 1.00
166_I 201_L 2.121 1.00
33_V 42_A 2.118 1.00
62_D 134_R 2.097 1.00
33_V 91_I 2.048 1.00
99_P 104_S 2.016 1.00
54_P 82_E 1.996 1.00
54_P 80_R 1.983 1.00
37_A 100_E 1.918 1.00
109_N 134_R 1.887 1.00
111_R 132_K 1.706 1.00
105_L 175_V 1.701 1.00
144_L 172_Y 1.678 1.00
38_S 142_A 1.676 1.00
99_P 102_K 1.666 1.00
62_D 109_N 1.666 1.00
157_F 166_I 1.654 1.00
150_D 153_K 1.647 1.00
72_F 91_I 1.639 1.00
148_V 151_A 1.598 1.00
154_S 170_T 1.583 0.99
165_N 200_Q 1.545 0.99
91_I 137_M 1.506 0.99
82_E 85_D 1.501 0.99
217_N 223_S 1.494 0.99
36_D 42_A 1.494 0.99
217_N 221_G 1.485 0.99
155_L 166_I 1.483 0.99
151_A 174_V 1.464 0.99
193_I 199_K 1.451 0.99
93_K 96_D 1.451 0.99
74_I 89_L 1.436 0.99
174_V 215_A 1.432 0.99
158_K 165_N 1.402 0.98
26_I 81_L 1.393 0.98
165_N 198_H 1.378 0.98
28_L 110_V 1.374 0.98
46_V 57_L 1.355 0.98
45_P 86_D 1.344 0.98
74_I 91_I 1.336 0.98
28_L 44_L 1.317 0.97
51_A 84_G 1.313 0.97
62_D 107_Y 1.3 0.97
138_F 173_Y 1.296 0.97
27_V 30_R 1.287 0.97
175_V 215_A 1.282 0.97
33_V 135_I 1.274 0.97
54_P 115_A 1.247 0.96
89_L 108_I 1.246 0.96
105_L 138_F 1.235 0.96
157_F 179_L 1.231 0.96
211_V 215_A 1.226 0.96
35_Y 42_A 1.223 0.96
163_S 200_Q 1.209 0.95
158_K 167_Y 1.205 0.95
160_S 165_N 1.203 0.95
57_L 79_F 1.2 0.95
160_S 163_S 1.197 0.95
87_S 111_R 1.187 0.95
25_G 112_A 1.174 0.94
74_I 108_I 1.164 0.94
113_I 131_F 1.16 0.94
89_L 110_V 1.158 0.94
107_Y 111_R 1.145 0.93
193_I 197_E 1.138 0.93
176_F 193_I 1.122 0.92
59_S 89_L 1.114 0.92
93_K 97_N 1.096 0.91
59_S 110_V 1.093 0.91
93_K 139_Y 1.082 0.90
146_G 150_D 1.076 0.90
81_L 86_D 1.058 0.89
215_A 223_S 1.053 0.89
103_E 140_R 1.034 0.87
110_V 135_I 1.033 0.87
60_W 134_R 1.031 0.87
50_G 112_A 1.027 0.87
88_S 132_K 1.027 0.87
87_S 112_A 1.025 0.87
56_L 172_Y 1.024 0.87
166_I 176_F 1.024 0.87
155_L 176_F 1.014 0.86
178_G 214_A 1.013 0.86
152_W 174_V 1.013 0.86
56_L 111_R 1.011 0.86
125_N 134_R 1.007 0.85
152_W 213_W 1.003 0.85
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4djmA80.9741000.153Contact Map0.804
1klfA80.88311000.161Contact Map0.794
1l4iA20.87881000.169Contact Map0.776
2co7B10.93511000.169Contact Map0.733
4ay0A20.92211000.185Contact Map0.762
2xg5A10.86581000.198Contact Map0.783
3gfuC20.84851000.204Contact Map0.695
3q48A20.9741000.213Contact Map0.806
1mspA20.493553.90.945Contact Map0.565
1z9lA10.497825.60.954Contact Map0.701

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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