May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
PTPC1 - N-acetylgalactosamine permease IIC component 1
UniProt: P42910 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12770
Length: 267 (250)
Sequences: 759
Seq/Len: 3.04
PTPC1
Paralog alert: 0.85 [within 20: 0.15] - ratio of genomes with paralogs
Cluster includes: PTNC PTPC1
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
46_D 49_T 4.251 1.00
42_A 47_I 3.455 1.00
133_D 136_A 3.237 1.00
212_A 234_G 3.148 1.00
222_V 227_P 3.144 1.00
180_H 184_V 2.797 1.00
32_R 58_E 2.757 1.00
9_G 13_A 2.695 1.00
128_C 136_A 2.325 1.00
17_F 149_A 2.146 1.00
15_L 39_L 2.102 1.00
37_C 50_G 2.073 1.00
124_K 127_K 2.042 1.00
215_L 231_L 1.99 1.00
15_L 43_I 1.982 1.00
127_K 130_K 1.956 1.00
128_C 131_E 1.893 0.99
176_A 180_H 1.89 0.99
211_I 230_V 1.865 0.99
168_Q 172_K 1.864 0.99
127_K 131_E 1.832 0.99
136_A 139_R 1.814 0.99
6_L 10_L 1.791 0.99
135_A 139_R 1.736 0.99
13_A 157_F 1.718 0.99
128_C 133_D 1.706 0.98
77_M 107_M 1.701 0.98
39_L 43_I 1.669 0.98
215_L 230_V 1.618 0.98
24_W 71_Q 1.593 0.97
180_H 183_E 1.531 0.96
44_L 88_S 1.526 0.96
13_A 153_A 1.525 0.96
124_K 128_C 1.475 0.95
6_L 161_Y 1.47 0.95
16_V 156_A 1.464 0.95
17_F 153_A 1.418 0.94
18_V 30_L 1.398 0.93
69_G 186_G 1.359 0.92
7_L 11_S 1.345 0.91
133_D 139_R 1.331 0.91
219_Y 222_V 1.33 0.91
129_A 137_F 1.326 0.90
165_G 168_Q 1.323 0.90
123_T 126_D 1.31 0.90
48_Q 52_I 1.301 0.89
36_V 80_L 1.298 0.89
163_A 182_F 1.297 0.89
125_A 140_L 1.286 0.89
95_T 98_G 1.256 0.87
11_S 43_I 1.237 0.86
99_L 103_F 1.229 0.85
8_Q 12_L 1.225 0.85
8_Q 43_I 1.223 0.85
15_L 36_V 1.209 0.84
49_T 53_T 1.196 0.83
254_V 257_K 1.196 0.83
185_A 189_L 1.195 0.83
169_A 172_K 1.191 0.83
86_A 96_A 1.185 0.82
229_A 236_A 1.181 0.82
56_L 60_A 1.16 0.81
165_G 169_A 1.159 0.80
238_Y 241_F 1.152 0.80
34_I 38_T 1.151 0.80
229_A 232_G 1.149 0.80
59_L 198_L 1.145 0.79
184_V 187_G 1.144 0.79
157_F 161_Y 1.144 0.79
108_Q 196_L 1.142 0.79
158_L 231_L 1.14 0.79
125_A 141_N 1.136 0.79
73_P 104_S 1.135 0.79
78_A 84_V 1.125 0.78
78_A 104_S 1.125 0.78
129_A 133_D 1.123 0.77
166_A 169_A 1.122 0.77
207_I 211_I 1.111 0.76
217_V 228_V 1.109 0.76
38_T 47_I 1.106 0.76
149_A 153_A 1.093 0.75
12_L 40_T 1.093 0.75
181_G 185_A 1.09 0.74
136_A 140_L 1.09 0.74
8_Q 11_S 1.084 0.74
134_T 138_S 1.077 0.73
50_G 54_G 1.076 0.73
94_K 172_K 1.071 0.73
230_V 233_A 1.067 0.72
129_A 136_A 1.064 0.72
108_Q 171_V 1.062 0.72
102_P 106_L 1.056 0.71
35_I 38_T 1.053 0.71
110_V 155_I 1.052 0.71
14_A 42_A 1.043 0.70
117_A 147_I 1.04 0.69
63_G 102_P 1.036 0.69
106_L 171_V 1.025 0.68
5_T 8_Q 1.024 0.68
130_K 143_T 1.021 0.67
170_L 173_A 1.017 0.67
12_L 44_L 1.01 0.66
230_V 234_G 1.009 0.66
40_T 84_V 1.007 0.66
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
4ltoA40.44573.60.974Contact Map0.367
4kjrA20.6033.30.975Contact Map0.457
2i68A20.43822.40.977Contact Map0.015
4k1cA20.68542.20.977Contact Map0.429
2vpbB10.11991.70.978Contact Map0.279
4b19A10.10861.50.979Contact Map0.441
2wscI10.14981.50.979Contact Map0.617
3lw5I10.11241.50.979Contact Map0.617
2rr3B10.08991.40.979Contact Map0
2llmA10.15731.20.98Contact Map0.261
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 0.6015 seconds.