May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
YQJG - Glutathionyl-hydroquinone reductase YqjG
UniProt: P42620 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12746
Length: 328 (326)
Sequences: 958
Seq/Len: 2.94
YQJG
Paralog alert: 0.11 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
190_V 220_L 3.987 1.00
263_R 266_D 3.2 1.00
189_T 216_S 3.12 1.00
211_A 311_I 2.968 1.00
52_K 81_F 2.91 1.00
117_Y 121_L 2.89 1.00
185_W 219_R 2.786 1.00
74_K 79_E 2.74 1.00
188_D 196_K 2.633 1.00
114_E 118_Q 2.632 1.00
123_A 143_T 2.6 1.00
171_Y 176_Q 2.333 1.00
111_Y 142_H 2.295 1.00
174_A 234_Q 2.286 1.00
182_L 186_I 2.281 1.00
70_L 84_V 2.251 1.00
61_L 288_N 2.235 1.00
22_K 208_E 2.217 1.00
5_I 10_H 2.203 1.00
301_K 307_G 2.158 1.00
184_G 188_D 2.154 1.00
72_M 240_I 2.149 1.00
116_L 135_V 2.1 1.00
264_I 274_L 2.096 1.00
272_G 322_G 2.086 1.00
228_R 276_D 2.078 1.00
171_Y 180_D 2.07 1.00
51_E 140_K 2.014 1.00
59_V 70_L 2.014 1.00
322_G 326_R 1.965 1.00
62_A 295_H 1.952 0.99
74_K 285_E 1.87 0.99
59_V 86_V 1.866 0.99
246_L 273_F 1.829 0.99
295_H 300_H 1.824 0.99
243_W 287_V 1.822 0.99
72_M 153_I 1.818 0.99
196_K 212_K 1.8 0.99
207_D 311_I 1.781 0.99
255_T 297_F 1.77 0.99
190_V 216_S 1.769 0.99
220_L 270_L 1.734 0.99
154_R 237_E 1.689 0.98
185_W 216_S 1.689 0.98
240_I 277_I 1.685 0.98
265_S 271_Y 1.682 0.98
35_T 38_G 1.672 0.98
298_R 307_G 1.666 0.98
276_D 280_M 1.665 0.98
122_H 142_H 1.636 0.98
202_S 205_A 1.636 0.98
62_A 300_H 1.632 0.98
157_N 169_D 1.629 0.98
72_M 170_Y 1.629 0.98
35_T 47_G 1.622 0.97
221_E 268_L 1.617 0.97
276_D 279_Q 1.605 0.97
106_T 109_T 1.558 0.97
197_A 213_V 1.556 0.97
252_V 256_H 1.535 0.96
189_T 212_K 1.521 0.96
256_H 300_H 1.512 0.96
185_W 189_T 1.507 0.96
197_A 210_V 1.496 0.95
271_Y 274_L 1.481 0.95
225_G 269_N 1.473 0.95
33_W 155_M 1.455 0.94
205_A 209_A 1.453 0.94
36_A 162_A 1.442 0.94
56_H 85_S 1.438 0.94
262_H 267_Y 1.418 0.93
279_Q 321_H 1.417 0.93
41_G 44_G 1.405 0.93
210_V 261_K 1.404 0.93
290_D 294_N 1.397 0.93
252_V 300_H 1.385 0.92
38_G 47_G 1.371 0.92
182_L 223_I 1.368 0.92
76_K 161_D 1.368 0.92
183_N 241_R 1.368 0.92
3_Q 12_T 1.366 0.92
235_L 280_M 1.36 0.91
178_K 181_E 1.358 0.91
85_S 109_T 1.355 0.91
173_P 176_Q 1.349 0.91
324_D 327_F 1.345 0.91
218_A 262_H 1.338 0.90
251_P 317_L 1.328 0.90
94_N 117_Y 1.307 0.89
52_K 163_L 1.301 0.89
221_E 269_N 1.29 0.88
256_H 295_H 1.29 0.88
216_S 219_R 1.285 0.88
111_Y 119_L 1.285 0.88
276_D 323_R 1.285 0.88
293_R 312_G 1.284 0.88
83_S 109_T 1.277 0.88
283_I 287_V 1.268 0.87
256_H 303_I 1.267 0.87
178_K 223_I 1.253 0.86
25_R 192_N 1.246 0.86
43_T 151_E 1.232 0.85
40_P 46_G 1.229 0.85
182_L 231_T 1.226 0.84
94_N 115_F 1.202 0.83
261_K 311_I 1.194 0.82
297_F 309_I 1.194 0.82
146_S 155_M 1.193 0.82
322_G 327_F 1.189 0.82
190_V 213_V 1.183 0.81
189_T 219_R 1.179 0.81
294_N 298_R 1.174 0.81
62_A 256_H 1.17 0.81
252_V 295_H 1.168 0.80
48_F 141_N 1.157 0.79
228_R 279_Q 1.15 0.79
59_V 84_V 1.141 0.78
196_K 209_A 1.14 0.78
32_N 48_F 1.137 0.78
83_S 119_L 1.137 0.78
228_R 323_R 1.136 0.78
228_R 321_H 1.13 0.77
89_P 294_N 1.122 0.77
235_L 277_I 1.117 0.76
81_F 164_G 1.114 0.76
293_R 310_S 1.112 0.76
25_R 65_W 1.11 0.75
271_Y 275_R 1.108 0.75
67_H 286_T 1.105 0.75
85_S 106_T 1.104 0.75
170_Y 240_I 1.103 0.75
279_Q 323_R 1.096 0.74
187_Y 192_N 1.096 0.74
274_L 317_L 1.094 0.74
218_A 267_Y 1.088 0.73
67_H 244_T 1.087 0.73
272_G 276_D 1.085 0.73
56_H 139_K 1.079 0.72
165_A 168_G 1.068 0.71
76_K 157_N 1.062 0.71
260_D 293_R 1.055 0.70
113_N 122_H 1.054 0.70
90_L 294_N 1.053 0.70
255_T 306_T 1.053 0.70
81_F 163_L 1.047 0.69
258_K 304_N 1.047 0.69
67_H 287_V 1.045 0.69
179_I 183_N 1.044 0.69
65_W 192_N 1.038 0.68
111_Y 122_H 1.036 0.68
272_G 279_Q 1.034 0.68
37_D 47_G 1.032 0.68
58_Y 108_D 1.025 0.67
271_Y 317_L 1.023 0.67
164_G 168_G 1.023 0.67
74_K 156_F 1.023 0.67
53_D 83_S 1.021 0.66
65_W 187_Y 1.02 0.66
293_R 297_F 1.015 0.66
71_I 240_I 1.014 0.66
11_D 14_Y 1.01 0.65
35_T 49_I 1.01 0.65
247_V 274_L 1.008 0.65
282_G 285_E 1.005 0.65
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4g0iA211000.347Contact Map0.712
3m1gA30.98481000.382Contact Map0.734
3ppuA20.95731000.417Contact Map0.759
4fquA80.95431000.467Contact Map0.738
2yv9A20.76221000.689Contact Map0.391
4g10A10.71651000.692Contact Map0.388
4mzwA20.751000.715Contact Map0.551
1b8xA10.69821000.738Contact Map0.462
4bjvA10.664699.90.814Contact Map0.585
4kf9A10.716599.90.821Contact Map0.396
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 1.0154 seconds.