| UniProt: | P39408 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12598 | ||
| Length: | 259 (255) | ||
| Sequences: | 3415 | ||
| Seq/Len: | 13.39 |
| YJJV
Paralog alert: 0.46 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: TATD YCFH YJJV |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 82_Q | 125_R | 3.536 | 1.00 | |
| 102_L | 140_K | 3.38 | 1.00 | |
| 117_D | 147_R | 3.203 | 1.00 | |
| 232_V | 235_E | 2.972 | 1.00 | |
| 120_L | 130_V | 2.727 | 1.00 | |
| 27_R | 222_R | 2.467 | 1.00 | |
| 163_L | 196_K | 2.321 | 1.00 | |
| 154_G | 174_Y | 2.237 | 1.00 | |
| 18_S | 21_E | 2.175 | 1.00 | |
| 250_N | 254_T | 2.174 | 1.00 | |
| 113_Q | 140_K | 2.122 | 1.00 | |
| 26_Q | 30_Q | 2.077 | 1.00 | |
| 139_D | 143_M | 2.043 | 1.00 | |
| 146_K | 168_R | 2.02 | 1.00 | |
| 85_L | 95_V | 1.968 | 1.00 | |
| 230_F | 241_A | 1.936 | 1.00 | |
| 199_L | 247_A | 1.928 | 1.00 | |
| 134_S | 141_L | 1.908 | 1.00 | |
| 167_E | 171_Q | 1.899 | 1.00 | |
| 239_E | 244_I | 1.888 | 1.00 | |
| 62_A | 94_A | 1.859 | 1.00 | |
| 246_Q | 250_N | 1.858 | 1.00 | |
| 98_I | 130_V | 1.856 | 1.00 | |
| 191_R | 232_V | 1.827 | 1.00 | |
| 121_K | 148_H | 1.81 | 1.00 | |
| 35_K | 253_Y | 1.756 | 1.00 | |
| 199_L | 239_E | 1.753 | 1.00 | |
| 231_A | 241_A | 1.75 | 1.00 | |
| 20_D | 220_P | 1.747 | 1.00 | |
| 199_L | 237_R | 1.741 | 1.00 | |
| 116_L | 141_L | 1.74 | 1.00 | |
| 22_E | 55_N | 1.724 | 1.00 | |
| 10_C | 36_I | 1.721 | 1.00 | |
| 8_T | 252_T | 1.699 | 1.00 | |
| 194_I | 233_L | 1.693 | 1.00 | |
| 178_V | 194_I | 1.68 | 1.00 | |
| 54_E | 87_R | 1.664 | 1.00 | |
| 5_F | 226_A | 1.662 | 1.00 | |
| 98_I | 119_Q | 1.654 | 1.00 | |
| 62_A | 131_I | 1.625 | 1.00 | |
| 192_D | 195_A | 1.619 | 1.00 | |
| 163_L | 167_E | 1.617 | 1.00 | |
| 146_K | 172_L | 1.608 | 1.00 | |
| 188_S | 192_D | 1.589 | 1.00 | |
| 117_D | 148_H | 1.583 | 1.00 | |
| 175_K | 201_S | 1.575 | 1.00 | |
| 227_A | 231_A | 1.565 | 1.00 | |
| 155_V | 255_L | 1.552 | 1.00 | |
| 168_R | 171_Q | 1.552 | 1.00 | |
| 182_I | 233_L | 1.538 | 1.00 | |
| 29_A | 58_P | 1.538 | 1.00 | |
| 191_R | 236_L | 1.521 | 1.00 | |
| 6_I | 35_K | 1.519 | 1.00 | |
| 47_A | 80_Q | 1.517 | 1.00 | |
| 249_L | 252_T | 1.514 | 1.00 | |
| 51_A | 55_N | 1.509 | 1.00 | |
| 10_C | 208_A | 1.502 | 1.00 | |
| 118_E | 121_K | 1.493 | 1.00 | |
| 102_L | 113_Q | 1.473 | 1.00 | |
| 167_E | 196_K | 1.463 | 1.00 | |
| 162_S | 165_Q | 1.452 | 1.00 | |
| 113_Q | 143_M | 1.44 | 1.00 | |
| 61_A | 92_V | 1.429 | 1.00 | |
| 40_A | 46_F | 1.418 | 1.00 | |
| 5_F | 230_F | 1.398 | 0.99 | |
| 114_W | 118_E | 1.397 | 0.99 | |
| 6_I | 249_L | 1.392 | 0.99 | |
| 143_M | 147_R | 1.374 | 0.99 | |
| 158_G | 179_G | 1.372 | 0.99 | |
| 13_D | 45_N | 1.371 | 0.99 | |
| 178_V | 202_L | 1.369 | 0.99 | |
| 117_D | 144_H | 1.369 | 0.99 | |
| 166_A | 176_I | 1.369 | 0.99 | |
| 203_L | 255_L | 1.367 | 0.99 | |
| 82_Q | 126_Y | 1.363 | 0.99 | |
| 85_L | 126_Y | 1.357 | 0.99 | |
| 17_F | 220_P | 1.354 | 0.99 | |
| 39_P | 131_I | 1.338 | 0.99 | |
| 6_I | 37_I | 1.336 | 0.99 | |
| 204_L | 230_F | 1.336 | 0.99 | |
| 240_P | 243_E | 1.335 | 0.99 | |
| 156_V | 169_F | 1.334 | 0.99 | |
| 42_E | 45_N | 1.333 | 0.99 | |
| 243_E | 246_Q | 1.329 | 0.99 | |
| 184_Y | 212_P | 1.318 | 0.99 | |
| 231_A | 235_E | 1.315 | 0.99 | |
| 127_D | 153_T | 1.314 | 0.99 | |
| 142_A | 168_R | 1.31 | 0.99 | |
| 248_L | 252_T | 1.31 | 0.99 | |
| 170_V | 201_S | 1.309 | 0.99 | |
| 28_A | 36_I | 1.306 | 0.99 | |
| 35_K | 60_Y | 1.305 | 0.99 | |
| 134_S | 138_H | 1.302 | 0.99 | |
| 188_S | 191_R | 1.28 | 0.99 | |
| 53_A | 61_A | 1.264 | 0.99 | |
| 113_Q | 144_H | 1.258 | 0.99 | |
| 198_P | 201_S | 1.242 | 0.98 | |
| 124_K | 148_H | 1.233 | 0.98 | |
| 113_Q | 117_D | 1.217 | 0.98 | |
| 108_Q | 111_R | 1.191 | 0.98 | |
| 116_L | 132_L | 1.189 | 0.98 | |
| 249_L | 253_Y | 1.188 | 0.98 | |
| 175_K | 254_T | 1.184 | 0.98 | |
| 37_I | 93_V | 1.183 | 0.98 | |
| 216_F | 228_R | 1.175 | 0.98 | |
| 20_D | 23_A | 1.174 | 0.98 | |
| 155_V | 256_F | 1.166 | 0.97 | |
| 139_D | 168_R | 1.166 | 0.97 | |
| 109_F | 113_Q | 1.148 | 0.97 | |
| 233_L | 244_I | 1.146 | 0.97 | |
| 80_Q | 83_Q | 1.138 | 0.97 | |
| 38_V | 49_V | 1.134 | 0.97 | |
| 204_L | 233_L | 1.132 | 0.97 | |
| 110_E | 114_W | 1.121 | 0.97 | |
| 51_A | 54_E | 1.118 | 0.96 | |
| 68_G | 104_G | 1.113 | 0.96 | |
| 121_K | 125_R | 1.11 | 0.96 | |
| 204_L | 226_A | 1.094 | 0.96 | |
| 176_I | 197_L | 1.086 | 0.96 | |
| 25_L | 36_I | 1.083 | 0.96 | |
| 23_A | 27_R | 1.077 | 0.95 | |
| 78_L | 118_E | 1.074 | 0.95 | |
| 82_Q | 86_E | 1.066 | 0.95 | |
| 25_L | 56_Y | 1.062 | 0.95 | |
| 138_H | 161_G | 1.061 | 0.95 | |
| 194_I | 237_R | 1.061 | 0.95 | |
| 226_A | 229_V | 1.06 | 0.95 | |
| 239_E | 243_E | 1.058 | 0.95 | |
| 54_E | 91_K | 1.057 | 0.95 | |
| 228_R | 231_A | 1.057 | 0.95 | |
| 132_L | 156_V | 1.055 | 0.95 | |
| 139_D | 165_Q | 1.055 | 0.95 | |
| 197_L | 202_L | 1.05 | 0.94 | |
| 138_H | 165_Q | 1.048 | 0.94 | |
| 22_E | 56_Y | 1.017 | 0.93 | |
| 164_Q | 167_E | 1.016 | 0.93 | |
| 124_K | 149_D | 1.013 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3e2vA | 2 | 0.9884 | 100 | 0.149 | Contact Map | 0.79 |
| 3ipwA | 1 | 0.9923 | 100 | 0.223 | Contact Map | 0.769 |
| 2xioA | 1 | 0.9846 | 100 | 0.301 | Contact Map | 0.772 |
| 1j6oA | 1 | 0.9884 | 100 | 0.318 | Contact Map | 0.776 |
| 3gg7A | 1 | 0.9382 | 100 | 0.337 | Contact Map | 0.583 |
| 3rcmA | 1 | 0.9846 | 100 | 0.358 | Contact Map | 0.746 |
| 1xwyA | 1 | 0.9923 | 100 | 0.362 | Contact Map | 0.753 |
| 1zzmA | 1 | 1 | 100 | 0.366 | Contact Map | 0.73 |
| 2gzxA | 2 | 0.9807 | 100 | 0.371 | Contact Map | 0.845 |
| 2y1hA | 2 | 0.9807 | 100 | 0.377 | Contact Map | 0.776 |
Sequence Conservation (Image Generated using WebLogo v3)