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YJIL - Uncharacterized protein YjiL
UniProt: P39383 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12573
Length: 255 (251)
Sequences: 1166
Seq/Len: 4.65
YJIL
Paralog alert: 0.51 [within 20: 0.45] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
17_I 24_I 3.9 1.00
35_R 38_T 3.059 1.00
149_E 179_E 2.718 1.00
82_L 250_R 2.524 1.00
5_I 18_L 2.345 1.00
27_R 238_F 2.237 1.00
148_T 217_K 2.202 1.00
80_H 240_G 2.195 1.00
151_V 180_A 2.18 1.00
202_C 206_I 2.178 1.00
90_A 205_P 2.109 1.00
139_T 147_I 2.045 1.00
140_S 143_Q 1.995 1.00
18_L 47_L 1.951 1.00
22_G 86_F 1.95 1.00
74_V 247_I 1.926 1.00
91_T 207_L 1.899 1.00
143_Q 146_S 1.893 1.00
168_A 181_I 1.881 1.00
223_E 229_P 1.879 1.00
205_P 229_P 1.833 1.00
38_T 42_E 1.762 1.00
17_I 242_I 1.75 1.00
153_P 183_A 1.686 0.99
156_I 164_A 1.664 0.99
19_L 242_I 1.635 0.99
95_I 197_I 1.622 0.99
80_H 239_A 1.621 0.99
58_T 248_G 1.607 0.99
16_G 47_L 1.604 0.99
220_R 223_E 1.594 0.99
150_N 180_A 1.589 0.99
62_Y 96_D 1.583 0.99
82_L 86_F 1.583 0.99
85_R 90_A 1.564 0.99
84_A 94_V 1.563 0.99
88_A 207_L 1.541 0.99
176_V 180_A 1.509 0.98
3_Y 25_T 1.501 0.98
172_R 181_I 1.48 0.98
212_V 218_F 1.462 0.98
204_A 228_M 1.452 0.98
144_L 182_L 1.438 0.98
40_I 67_V 1.421 0.97
206_I 228_M 1.42 0.97
194_A 197_I 1.373 0.96
177_A 180_A 1.368 0.96
220_R 224_S 1.312 0.95
22_G 249_Q 1.31 0.95
187_N 225_H 1.307 0.95
95_I 193_S 1.3 0.95
24_I 242_I 1.298 0.95
11_S 101_D 1.288 0.94
45_E 49_E 1.285 0.94
187_N 224_S 1.279 0.94
133_I 168_A 1.273 0.94
27_R 235_D 1.255 0.93
106_Q 201_S 1.254 0.93
86_F 242_I 1.254 0.93
77_I 118_M 1.251 0.93
95_I 104_V 1.23 0.92
213_S 236_A 1.228 0.92
7_I 67_V 1.224 0.92
4_S 248_G 1.209 0.92
101_D 118_M 1.189 0.91
41_T 45_E 1.186 0.91
133_I 189_M 1.186 0.91
78_S 247_I 1.181 0.90
80_H 209_T 1.177 0.90
76_E 101_D 1.169 0.90
42_E 46_T 1.164 0.89
14_T 32_T 1.159 0.89
30_V 46_T 1.152 0.89
58_T 244_A 1.15 0.89
11_S 103_K 1.143 0.88
146_S 216_Q 1.142 0.88
99_G 103_K 1.137 0.88
25_T 68_D 1.134 0.88
86_F 246_V 1.133 0.88
77_I 113_L 1.125 0.87
123_A 192_R 1.117 0.87
118_M 126_T 1.113 0.86
15_K 185_V 1.105 0.86
62_Y 101_D 1.101 0.86
152_T 180_A 1.101 0.86
219_A 232_T 1.097 0.85
28_F 46_T 1.096 0.85
103_K 118_M 1.094 0.85
64_R 120_D 1.089 0.85
145_D 215_C 1.086 0.85
46_T 49_E 1.086 0.85
59_L 67_V 1.083 0.84
29_L 238_F 1.079 0.84
14_T 43_A 1.072 0.84
24_I 27_R 1.069 0.83
236_A 239_A 1.065 0.83
43_A 238_F 1.062 0.83
16_G 43_A 1.059 0.83
157_T 167_E 1.057 0.82
145_D 186_I 1.056 0.82
130_L 212_V 1.05 0.82
76_E 103_K 1.037 0.81
147_I 179_E 1.036 0.81
145_D 217_K 1.035 0.80
46_T 50_G 1.035 0.80
205_P 231_N 1.034 0.80
132_V 161_T 1.034 0.80
92_R 203_E 1.031 0.80
209_T 239_A 1.029 0.80
139_T 195_N 1.029 0.80
43_A 47_L 1.023 0.79
146_S 149_E 1.023 0.79
58_T 72_K 1.018 0.79
130_L 141_V 1.014 0.79
213_S 232_T 1.012 0.78
217_K 221_M 1.005 0.78
196_F 200_L 1.005 0.78
62_Y 103_K 1.003 0.78
190_A 225_H 1.001 0.77
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2ewsA20.91371000.46Contact Map0.604
2i7nA20.97251000.488Contact Map0.482
4ehuA20.99221000.554Contact Map0.757
1huxA20.99221000.577Contact Map0.702
3enoA20.98821000.621Contact Map0.386
3en9A20.98821000.629Contact Map0.48
2ivnA10.98041000.646Contact Map0.403
3zeuB20.98431000.654Contact Map0.385
3qbxA20.99221000.676Contact Map0.367
3cqyA20.99221000.678Contact Map0.319
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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