| UniProt: | P37745 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11979 | ||
| Length: | 185 (178) | ||
| Sequences: | 2044 | ||
| Seq/Len: | 11.48 |
| RMLC
Paralog alert: 0.18 [within 20: 0.02] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 145_G | 172_L | 3.988 | 1.00 | |
| 80_A | 102_L | 3.759 | 1.00 | |
| 125_S | 128_A | 3.429 | 1.00 | |
| 81_V | 130_F | 3.345 | 1.00 | |
| 32_Q | 44_S | 3.322 | 1.00 | |
| 82_F | 100_G | 2.734 | 1.00 | |
| 61_L | 118_A | 2.602 | 1.00 | |
| 152_R | 176_D | 2.589 | 1.00 | |
| 5_R | 12_L | 2.468 | 1.00 | |
| 7_E | 97_K | 2.467 | 1.00 | |
| 139_H | 142_S | 2.44 | 1.00 | |
| 15_E | 109_Q | 2.434 | 1.00 | |
| 7_E | 99_V | 2.397 | 1.00 | |
| 78_H | 105_A | 2.344 | 1.00 | |
| 71_D | 112_W | 2.323 | 1.00 | |
| 71_D | 135_T | 2.301 | 1.00 | |
| 58_L | 122_L | 2.232 | 1.00 | |
| 65_R | 144_C | 2.212 | 1.00 | |
| 48_D | 133_K | 2.177 | 1.00 | |
| 51_S | 121_F | 2.17 | 1.00 | |
| 4_I | 15_E | 2.125 | 1.00 | |
| 36_E | 42_P | 2.098 | 1.00 | |
| 13_I | 109_Q | 2.074 | 1.00 | |
| 33_S | 137_Y | 2.046 | 1.00 | |
| 78_H | 127_I | 2.032 | 1.00 | |
| 115_K | 135_T | 2.032 | 1.00 | |
| 32_Q | 36_E | 2.003 | 1.00 | |
| 104_S | 107_N | 1.956 | 1.00 | |
| 2_N | 15_E | 1.953 | 1.00 | |
| 147_C | 174_T | 1.871 | 1.00 | |
| 167_P | 171_R | 1.864 | 1.00 | |
| 55_K | 126_D | 1.858 | 1.00 | |
| 71_D | 115_K | 1.818 | 1.00 | |
| 77_T | 131_Q | 1.778 | 1.00 | |
| 80_A | 125_S | 1.769 | 1.00 | |
| 78_H | 129_E | 1.711 | 1.00 | |
| 174_T | 177_E | 1.699 | 1.00 | |
| 50_H | 129_E | 1.64 | 1.00 | |
| 5_R | 9_E | 1.624 | 1.00 | |
| 13_I | 101_V | 1.601 | 1.00 | |
| 167_P | 170_E | 1.593 | 1.00 | |
| 146_I | 153_I | 1.522 | 1.00 | |
| 50_H | 75_R | 1.505 | 1.00 | |
| 88_I | 118_A | 1.499 | 1.00 | |
| 63_F | 144_C | 1.499 | 1.00 | |
| 123_V | 128_A | 1.497 | 1.00 | |
| 82_F | 158_P | 1.495 | 1.00 | |
| 25_F | 50_H | 1.471 | 1.00 | |
| 8_I | 117_F | 1.467 | 1.00 | |
| 68_Y | 136_N | 1.43 | 1.00 | |
| 153_I | 175_L | 1.426 | 1.00 | |
| 52_R | 129_E | 1.401 | 0.99 | |
| 61_L | 120_G | 1.386 | 0.99 | |
| 6_T | 13_I | 1.344 | 0.99 | |
| 11_V | 85_A | 1.305 | 0.99 | |
| 152_R | 174_T | 1.298 | 0.99 | |
| 33_S | 37_H | 1.294 | 0.99 | |
| 18_V | 108_K | 1.294 | 0.99 | |
| 80_A | 104_S | 1.288 | 0.99 | |
| 31_N | 34_A | 1.233 | 0.98 | |
| 68_Y | 139_H | 1.229 | 0.98 | |
| 2_N | 17_R | 1.216 | 0.98 | |
| 11_V | 99_V | 1.186 | 0.98 | |
| 143_D | 172_L | 1.158 | 0.97 | |
| 52_R | 127_I | 1.154 | 0.97 | |
| 3_V | 12_L | 1.154 | 0.97 | |
| 8_I | 11_V | 1.127 | 0.97 | |
| 43_V | 112_W | 1.124 | 0.97 | |
| 114_P | 117_F | 1.12 | 0.96 | |
| 28_E | 70_Q | 1.106 | 0.96 | |
| 85_A | 99_V | 1.105 | 0.96 | |
| 26_F | 51_S | 1.093 | 0.96 | |
| 122_L | 159_Q | 1.087 | 0.96 | |
| 84_V | 155_I | 1.084 | 0.96 | |
| 31_N | 137_Y | 1.082 | 0.96 | |
| 81_V | 128_A | 1.074 | 0.95 | |
| 115_K | 136_N | 1.073 | 0.95 | |
| 28_E | 31_N | 1.059 | 0.95 | |
| 68_Y | 142_S | 1.054 | 0.95 | |
| 148_W | 163_L | 1.049 | 0.94 | |
| 82_F | 98_W | 1.046 | 0.94 | |
| 122_L | 158_P | 1.045 | 0.94 | |
| 25_F | 129_E | 1.036 | 0.94 | |
| 43_V | 115_K | 1.029 | 0.94 | |
| 173_F | 177_E | 1.02 | 0.93 | |
| 45_F | 135_T | 1.014 | 0.93 | |
| 112_W | 115_K | 1.013 | 0.93 | |
| 22_D | 167_P | 1.005 | 0.93 | |
| 34_A | 38_I | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1upiA | 1 | 1 | 100 | 0.095 | Contact Map | 0.756 |
| 4hn1A | 4 | 0.9892 | 100 | 0.095 | Contact Map | 0.685 |
| 1oi6A | 2 | 1 | 100 | 0.096 | Contact Map | 0.75 |
| 2c0zA | 1 | 0.9946 | 100 | 0.099 | Contact Map | 0.72 |
| 3rykA | 2 | 0.973 | 100 | 0.122 | Contact Map | 0.812 |
| 1dzrA | 2 | 0.9838 | 100 | 0.124 | Contact Map | 0.859 |
| 2ixkA | 2 | 0.9784 | 100 | 0.126 | Contact Map | 0.873 |
| 1ep0A | 1 | 0.973 | 100 | 0.136 | Contact Map | 0.844 |
| 1wltA | 2 | 0.9405 | 100 | 0.175 | Contact Map | 0.75 |
| 1nxmA | 2 | 0.9459 | 100 | 0.181 | Contact Map | 0.753 |
Sequence Conservation (Image Generated using WebLogo v3)