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YIAH - Inner membrane protein YiaH
UniProt: P37669 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12274
Length: 331 (329)
Sequences: 745
Seq/Len: 2.26

YIAH
Paralog alert: 0.14 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: OPGC YIAH
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
58_F 123_A 3.094 1.00
18_M 52_V 3.033 1.00
119_W 123_A 2.91 1.00
280_F 314_S 2.625 1.00
4_K 9_D 2.342 1.00
75_H 82_C 2.341 1.00
12_R 60_I 2.299 1.00
71_A 75_H 2.229 1.00
120_F 123_A 2.054 0.99
90_A 117_H 2.033 0.99
13_G 274_S 1.986 0.99
319_M 323_R 1.929 0.99
59_M 66_F 1.897 0.99
71_A 128_Y 1.866 0.99
58_F 183_Y 1.821 0.98
89_I 283_L 1.798 0.98
13_G 271_S 1.781 0.98
51_R 118_L 1.769 0.98
284_I 313_A 1.763 0.98
51_R 117_H 1.753 0.98
20_V 125_A 1.749 0.98
17_L 311_L 1.735 0.97
284_I 317_L 1.695 0.97
47_N 117_H 1.689 0.97
80_G 125_A 1.685 0.97
65_F 71_A 1.681 0.97
276_G 318_S 1.665 0.96
71_A 82_C 1.646 0.96
123_A 126_V 1.633 0.96
90_A 118_L 1.623 0.96
273_H 319_M 1.616 0.96
65_F 128_Y 1.575 0.95
52_V 56_L 1.556 0.94
131_S 187_G 1.554 0.94
83_L 122_F 1.537 0.94
47_N 51_R 1.528 0.94
214_G 250_A 1.524 0.93
15_A 56_L 1.518 0.93
120_F 153_I 1.383 0.88
82_C 275_L 1.375 0.88
134_I 184_I 1.374 0.88
128_Y 132_P 1.372 0.88
61_S 187_G 1.369 0.87
58_F 124_I 1.368 0.87
16_C 277_I 1.367 0.87
47_N 118_L 1.361 0.87
22_I 51_R 1.349 0.86
51_R 64_L 1.345 0.86
59_M 252_L 1.329 0.85
54_V 278_Y 1.321 0.85
79_I 128_Y 1.317 0.85
22_I 53_S 1.316 0.85
58_F 127_I 1.312 0.84
121_F 280_F 1.303 0.84
8_I 60_I 1.272 0.82
182_Y 187_G 1.267 0.81
62_G 120_F 1.267 0.81
22_I 118_L 1.266 0.81
59_M 63_Y 1.257 0.81
63_Y 66_F 1.256 0.81
66_F 122_F 1.248 0.80
310_T 314_S 1.242 0.80
123_A 127_I 1.241 0.79
133_L 312_A 1.239 0.79
124_I 187_G 1.237 0.79
7_W 63_Y 1.234 0.79
182_Y 186_Y 1.228 0.78
64_L 186_Y 1.225 0.78
9_D 12_R 1.222 0.78
12_R 275_L 1.221 0.78
275_L 279_G 1.217 0.78
127_I 187_G 1.215 0.77
55_P 186_Y 1.215 0.77
120_F 183_Y 1.212 0.77
66_F 131_S 1.21 0.77
61_S 124_I 1.206 0.77
117_H 278_Y 1.202 0.76
316_L 320_L 1.199 0.76
86_Y 280_F 1.192 0.76
120_F 190_G 1.181 0.75
112_K 119_W 1.173 0.74
6_Y 9_D 1.173 0.74
48_S 51_R 1.17 0.74
135_Q 187_G 1.167 0.73
183_Y 187_G 1.167 0.73
84_I 181_F 1.166 0.73
122_F 126_V 1.166 0.73
121_F 275_L 1.161 0.73
22_I 54_V 1.15 0.72
117_H 281_H 1.149 0.72
60_I 183_Y 1.148 0.72
116_Y 282_A 1.143 0.71
12_R 273_H 1.137 0.71
53_S 239_Y 1.133 0.70
86_Y 90_A 1.128 0.70
71_A 126_V 1.125 0.69
312_A 319_M 1.123 0.69
88_A 109_L 1.12 0.69
63_Y 194_G 1.119 0.69
145_L 320_L 1.118 0.69
13_G 273_H 1.117 0.69
75_H 79_I 1.115 0.68
310_T 316_L 1.114 0.68
21_M 307_F 1.112 0.68
12_R 64_L 1.112 0.68
127_I 131_S 1.11 0.68
55_P 124_I 1.105 0.67
56_L 113_P 1.102 0.67
186_Y 190_G 1.101 0.67
19_V 57_F 1.097 0.67
88_A 316_L 1.096 0.66
61_S 131_S 1.096 0.66
82_C 122_F 1.094 0.66
66_F 83_L 1.088 0.66
74_R 79_I 1.087 0.66
93_Y 277_I 1.087 0.66
127_I 132_P 1.078 0.65
87_S 91_L 1.075 0.64
125_A 189_L 1.073 0.64
124_I 128_Y 1.07 0.64
3_P 268_G 1.06 0.63
65_F 75_H 1.058 0.62
121_F 183_Y 1.057 0.62
66_F 191_R 1.055 0.62
19_V 53_S 1.054 0.62
53_S 148_M 1.054 0.62
134_I 325_D 1.05 0.62
3_P 41_D 1.046 0.61
54_V 78_R 1.042 0.61
53_S 271_S 1.041 0.61
54_V 91_L 1.04 0.60
109_L 236_W 1.038 0.60
8_I 320_L 1.038 0.60
150_V 154_I 1.035 0.60
25_T 128_Y 1.034 0.60
178_G 182_Y 1.034 0.60
13_G 277_I 1.034 0.60
273_H 315_L 1.032 0.60
112_K 117_H 1.032 0.60
115_F 282_A 1.026 0.59
216_F 268_G 1.025 0.59
118_L 152_G 1.023 0.59
187_G 190_G 1.018 0.58
12_R 16_C 1.017 0.58
44_N 237_Y 1.011 0.57
59_M 122_F 1.011 0.57
121_F 185_L 1.007 0.57
81_L 319_M 1.006 0.57
117_H 277_I 1.005 0.57
9_D 271_S 1.004 0.56
20_V 310_T 1.001 0.56
325_D 329_L 1.001 0.56
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2cfqA10.22961.30.973Contact Map0.25
3ffvA20.1420.90.975Contact Map0
2gmqA20.18430.90.976Contact Map0.187
4gd3A20.17220.80.977Contact Map0.157
4kixP10.11780.70.977Contact Map0
3j3wP10.11780.70.977Contact Map0
3l22A10.16920.70.978Contact Map0
4i0uA100.20540.60.978Contact Map0.186
1rklA10.09970.60.978Contact Map0.137
2jssB10.06340.60.979Contact Map0

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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