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OPENSEQ.org
YHJJ - Protein YhjJ
UniProt: P37648 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12254
Length: 498 (434)
Sequences: 5491
Seq/Len: 12.65
YHJJ
Paralog alert: 0.81 [within 20: 0.37] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
368_E 372_N 5.197 1.00
202_A 206_K 4.878 1.00
357_E 360_K 4.491 1.00
360_K 364_K 4.073 1.00
153_P 157_N 3.87 1.00
227_D 230_S 3.713 1.00
432_M 435_Q 3.7 1.00
308_H 370_E 3.678 1.00
368_E 430_V 3.312 1.00
46_V 226_V 3.298 1.00
203_E 207_D 3.241 1.00
429_T 432_M 3.152 1.00
379_K 426_N 3.135 1.00
136_K 234_Q 3.075 1.00
39_S 236_N 2.815 1.00
359_A 363_D 2.803 1.00
90_G 148_K 2.788 1.00
74_Q 204_K 2.7 1.00
177_W 278_M 2.684 1.00
222_V 231_V 2.668 1.00
93_D 96_Q 2.577 1.00
346_K 349_S 2.536 1.00
91_G 140_S 2.456 1.00
78_S 208_F 2.43 1.00
61_L 220_L 2.407 1.00
207_D 211_K 2.394 1.00
144_N 148_K 2.352 1.00
37_T 43_Q 2.315 1.00
63_V 218_M 2.308 1.00
430_V 434_N 2.234 1.00
201_E 204_K 2.192 1.00
338_I 354_V 2.173 1.00
115_I 122_L 2.126 1.00
312_A 316_S 2.105 1.00
435_Q 439_Q 2.082 1.00
121_T 213_Y 2.079 1.00
365_G 434_N 2.013 1.00
136_K 237_K 1.993 1.00
34_Q 229_R 1.983 1.00
367_P 370_E 1.978 1.00
36_G 232_V 1.974 1.00
147_G 241_E 1.948 1.00
352_N 356_R 1.943 1.00
92_L 144_N 1.943 1.00
80_A 156_I 1.929 1.00
234_Q 238_T 1.868 1.00
42_L 220_L 1.866 1.00
233_D 237_K 1.854 1.00
431_E 435_Q 1.843 1.00
353_L 356_R 1.841 1.00
359_A 362_R 1.839 1.00
220_L 235_I 1.838 1.00
233_D 236_N 1.836 1.00
232_V 236_N 1.833 1.00
47_L 397_L 1.822 1.00
46_V 228_A 1.808 1.00
193_A 196_L 1.799 1.00
176_G 179_R 1.786 1.00
136_K 238_T 1.761 1.00
434_N 438_R 1.757 1.00
194_D 198_Q 1.745 1.00
362_R 438_R 1.74 1.00
312_A 357_E 1.735 1.00
91_G 144_N 1.734 1.00
372_N 376_A 1.733 1.00
50_P 225_N 1.727 1.00
348_N 352_N 1.719 1.00
92_L 100_L 1.714 1.00
300_L 366_L 1.713 1.00
42_L 218_M 1.703 1.00
152_T 155_T 1.69 1.00
230_S 233_D 1.673 1.00
77_Y 200_V 1.673 1.00
46_V 231_V 1.611 1.00
127_L 138_A 1.597 1.00
372_N 375_V 1.595 1.00
349_S 352_N 1.594 1.00
119_D 187_L 1.591 1.00
101_W 106_D 1.583 1.00
431_E 434_N 1.57 1.00
366_L 371_F 1.562 1.00
139_L 234_Q 1.558 1.00
290_A 439_Q 1.558 1.00
73_Q 204_K 1.553 1.00
62_L 402_M 1.54 1.00
226_V 231_V 1.536 1.00
89_S 144_N 1.529 1.00
48_T 227_D 1.522 1.00
156_I 205_I 1.518 1.00
81_I 151_I 1.512 1.00
230_S 234_Q 1.509 1.00
79_H 83_R 1.508 1.00
35_Q 43_Q 1.499 1.00
156_I 202_A 1.499 1.00
312_A 317_N 1.495 1.00
100_L 137_E 1.495 1.00
104_G 137_E 1.493 1.00
91_G 148_K 1.466 1.00
84_I 205_I 1.457 1.00
81_I 205_I 1.436 1.00
43_Q 219_T 1.417 1.00
79_H 82_P 1.413 1.00
371_F 430_V 1.412 1.00
356_R 360_K 1.41 1.00
59_I 222_V 1.402 0.99
71_S 74_Q 1.402 0.99
83_R 116_V 1.378 0.99
48_T 228_A 1.371 0.99
61_L 218_M 1.371 0.99
375_V 425_L 1.368 0.99
82_P 116_V 1.363 0.99
207_D 210_Q 1.335 0.99
161_Q 198_Q 1.329 0.99
118_Y 178_W 1.322 0.99
143_A 239_F 1.306 0.99
234_Q 237_K 1.301 0.99
437_L 441_L 1.296 0.99
82_P 86_L 1.294 0.99
65_T 208_F 1.291 0.99
36_G 44_W 1.277 0.99
435_Q 438_R 1.277 0.99
82_P 114_V 1.277 0.99
64_N 217_A 1.272 0.99
79_H 116_V 1.272 0.99
73_Q 196_L 1.27 0.99
136_K 230_S 1.266 0.99
298_A 327_C 1.265 0.99
153_P 202_A 1.261 0.99
84_I 156_I 1.255 0.99
139_L 235_I 1.254 0.99
424_F 427_S 1.252 0.99
90_G 150_T 1.247 0.99
203_E 206_K 1.243 0.98
342_S 350_N 1.238 0.98
310_Q 314_S 1.236 0.98
296_W 428_L 1.235 0.98
231_V 235_I 1.226 0.98
149_L 209_Y 1.224 0.98
125_L 138_A 1.224 0.98
355_A 359_A 1.222 0.98
290_A 435_Q 1.22 0.98
61_L 146_T 1.217 0.98
75_S 196_L 1.211 0.98
340_I 354_V 1.204 0.98
45_Q 219_T 1.197 0.98
83_R 113_P 1.192 0.98
322_G 325_F 1.19 0.98
96_Q 100_L 1.184 0.98
206_K 210_Q 1.181 0.98
82_P 213_Y 1.178 0.98
80_A 160_L 1.176 0.98
36_G 236_N 1.175 0.98
36_G 46_V 1.174 0.98
181_R 335_Q 1.167 0.97
298_A 302_R 1.165 0.97
115_I 120_T 1.164 0.97
135_L 231_V 1.164 0.97
87_T 159_A 1.163 0.97
137_E 140_S 1.16 0.97
142_L 145_A 1.157 0.97
34_Q 232_V 1.157 0.97
34_Q 228_A 1.154 0.97
228_A 232_V 1.15 0.97
166_V 194_D 1.147 0.97
215_P 242_L 1.137 0.97
97_A 141_Y 1.135 0.97
371_F 375_V 1.135 0.97
36_G 228_A 1.133 0.97
223_V 398_M 1.13 0.97
80_A 205_I 1.126 0.97
214_T 217_A 1.122 0.97
143_A 147_G 1.121 0.97
83_R 159_A 1.117 0.96
135_L 234_Q 1.112 0.96
44_W 232_V 1.111 0.96
375_V 426_N 1.111 0.96
57_V 224_G 1.11 0.96
236_N 240_G 1.107 0.96
204_K 207_D 1.103 0.96
92_L 140_S 1.097 0.96
38_L 44_W 1.097 0.96
85_A 149_L 1.093 0.96
40_N 215_P 1.092 0.96
74_Q 211_K 1.091 0.96
83_R 86_L 1.091 0.96
365_G 430_V 1.081 0.95
97_A 145_A 1.076 0.95
320_D 323_L 1.067 0.95
68_L 332_L 1.066 0.95
363_D 438_R 1.066 0.95
123_F 213_Y 1.061 0.95
273_D 347_L 1.057 0.95
82_P 121_T 1.054 0.95
35_Q 45_Q 1.05 0.94
140_S 238_T 1.047 0.94
89_S 148_K 1.04 0.94
216_D 244_G 1.036 0.94
143_A 238_T 1.032 0.94
202_A 205_I 1.031 0.94
304_A 307_W 1.027 0.94
79_H 86_L 1.027 0.94
89_S 92_L 1.027 0.94
380_L 384_K 1.027 0.94
101_W 112_P 1.026 0.94
340_I 350_N 1.025 0.93
349_S 353_L 1.022 0.93
35_Q 405_L 1.021 0.93
100_L 103_Q 1.005 0.93
372_N 426_N 1.004 0.93
160_L 163_Q 1.004 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3go9A10.96591000.352Contact Map0.693
3eoqA20.79721000.37Contact Map0.722
1hr6B40.84341000.373Contact Map0.754
1hr6A40.87951000.387Contact Map0.751
1pp9A20.85741000.388Contact Map0.738
3amiA20.85941000.388Contact Map0.75
3hdiA20.82731000.396Contact Map0.805
1q2lA10.90361000.425Contact Map0.616
3cx5A20.81931000.432Contact Map0.707
1pp9B20.84541000.434Contact Map0.692
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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