| UniProt: | P37326 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12413 | ||
| Length: | 385 (380) | ||
| Sequences: | 6272 | ||
| Seq/Len: | 16.51 |
| INTS
Paralog alert: 0.72 [within 20: 0.10] - ratio of genomes with paralogs Cluster includes: FIMB FIME INTA INTB INTD INTE INTF INTQ INTR INTS INTZ XERC XERD |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 131_L | 140_Q | 4.066 | 1.00 | |
| 331_S | 348_L | 3.642 | 1.00 | |
| 247_D | 250_N | 3.143 | 1.00 | |
| 322_S | 325_G | 3.087 | 1.00 | |
| 243_W | 282_S | 3.037 | 1.00 | |
| 66_K | 69_T | 2.698 | 1.00 | |
| 243_W | 292_V | 2.642 | 1.00 | |
| 242_L | 290_E | 2.625 | 1.00 | |
| 266_H | 349_A | 2.51 | 1.00 | |
| 97_Y | 167_V | 2.493 | 1.00 | |
| 330_F | 347_Q | 2.482 | 1.00 | |
| 94_S | 98_K | 2.418 | 1.00 | |
| 137_E | 140_Q | 2.407 | 1.00 | |
| 117_A | 121_D | 2.361 | 1.00 | |
| 251_R | 275_V | 2.358 | 1.00 | |
| 328_H | 362_H | 2.344 | 1.00 | |
| 4_V | 8_E | 2.326 | 1.00 | |
| 40_R | 47_E | 2.288 | 1.00 | |
| 96_I | 133_I | 2.258 | 1.00 | |
| 136_I | 168_F | 2.246 | 1.00 | |
| 148_F | 160_A | 2.235 | 1.00 | |
| 94_S | 130_G | 2.188 | 1.00 | |
| 251_R | 272_D | 2.158 | 1.00 | |
| 96_I | 171_A | 2.135 | 1.00 | |
| 98_K | 125_L | 2.123 | 1.00 | |
| 335_N | 344_I | 2.115 | 1.00 | |
| 232_A | 330_F | 2.089 | 1.00 | |
| 228_L | 323_G | 2.078 | 1.00 | |
| 60_L | 64_R | 2.071 | 1.00 | |
| 254_T | 267_V | 2.029 | 1.00 | |
| 223_I | 281_L | 2.02 | 1.00 | |
| 228_L | 238_L | 2.001 | 1.00 | |
| 252_I | 267_V | 1.99 | 1.00 | |
| 59_T | 62_E | 1.983 | 1.00 | |
| 270_M | 274_V | 1.967 | 1.00 | |
| 330_F | 334_M | 1.959 | 1.00 | |
| 69_T | 73_D | 1.957 | 1.00 | |
| 248_F | 275_V | 1.942 | 1.00 | |
| 97_Y | 120_F | 1.934 | 1.00 | |
| 235_T | 324_H | 1.912 | 1.00 | |
| 341_A | 357_R | 1.889 | 1.00 | |
| 42_K | 47_E | 1.877 | 1.00 | |
| 10_A | 19_L | 1.856 | 1.00 | |
| 141_L | 182_A | 1.845 | 1.00 | |
| 245_N | 256_D | 1.845 | 1.00 | |
| 94_S | 125_L | 1.825 | 1.00 | |
| 269_P | 347_Q | 1.824 | 1.00 | |
| 145_I | 161_R | 1.776 | 1.00 | |
| 374_Q | 378_D | 1.756 | 1.00 | |
| 173_V | 186_A | 1.735 | 1.00 | |
| 340_P | 343_A | 1.728 | 1.00 | |
| 40_R | 49_I | 1.719 | 1.00 | |
| 132_E | 135_D | 1.702 | 1.00 | |
| 112_Y | 116_L | 1.693 | 1.00 | |
| 243_W | 278_L | 1.657 | 1.00 | |
| 127_I | 147_R | 1.655 | 1.00 | |
| 241_M | 246_V | 1.635 | 1.00 | |
| 201_P | 204_Q | 1.616 | 1.00 | |
| 128_I | 144_V | 1.615 | 1.00 | |
| 155_E | 159_K | 1.606 | 1.00 | |
| 352_N | 358_G | 1.604 | 1.00 | |
| 172_I | 177_A | 1.6 | 1.00 | |
| 131_L | 135_D | 1.595 | 1.00 | |
| 224_A | 238_L | 1.592 | 1.00 | |
| 275_V | 279_T | 1.586 | 1.00 | |
| 170_Y | 174_T | 1.586 | 1.00 | |
| 169_R | 183_P | 1.58 | 1.00 | |
| 93_F | 136_I | 1.579 | 1.00 | |
| 335_N | 361_N | 1.568 | 1.00 | |
| 342_D | 345_E | 1.556 | 1.00 | |
| 222_L | 226_K | 1.551 | 1.00 | |
| 227_V | 274_V | 1.549 | 1.00 | |
| 175_G | 179_Y | 1.547 | 1.00 | |
| 233_L | 255_I | 1.531 | 1.00 | |
| 233_L | 238_L | 1.51 | 1.00 | |
| 5_K | 8_E | 1.51 | 1.00 | |
| 13_K | 17_Y | 1.508 | 1.00 | |
| 92_S | 95_A | 1.502 | 1.00 | |
| 331_S | 344_I | 1.484 | 1.00 | |
| 247_D | 252_I | 1.465 | 1.00 | |
| 204_Q | 207_A | 1.463 | 1.00 | |
| 101_Y | 113_A | 1.454 | 1.00 | |
| 264_K | 351_A | 1.441 | 1.00 | |
| 235_T | 239_R | 1.431 | 1.00 | |
| 198_P | 204_Q | 1.429 | 1.00 | |
| 270_M | 275_V | 1.42 | 1.00 | |
| 241_M | 253_I | 1.418 | 1.00 | |
| 109_S | 112_Y | 1.407 | 0.99 | |
| 169_R | 180_N | 1.404 | 0.99 | |
| 200_L | 208_F | 1.403 | 0.99 | |
| 96_I | 170_Y | 1.402 | 0.99 | |
| 334_M | 344_I | 1.398 | 0.99 | |
| 131_L | 136_I | 1.398 | 0.99 | |
| 93_F | 167_V | 1.394 | 0.99 | |
| 237_E | 266_H | 1.385 | 0.99 | |
| 120_F | 125_L | 1.384 | 0.99 | |
| 245_N | 259_V | 1.377 | 0.99 | |
| 229_R | 326_F | 1.374 | 0.99 | |
| 142_L | 146_R | 1.363 | 0.99 | |
| 271_S | 274_V | 1.354 | 0.99 | |
| 355_S | 359_I | 1.354 | 0.99 | |
| 161_R | 165_G | 1.342 | 0.99 | |
| 93_F | 164_C | 1.339 | 0.99 | |
| 168_F | 181_P | 1.337 | 0.99 | |
| 205_I | 229_R | 1.326 | 0.99 | |
| 98_K | 102_E | 1.315 | 0.99 | |
| 119_M | 163_R | 1.312 | 0.99 | |
| 230_Y | 271_S | 1.312 | 0.99 | |
| 248_F | 279_T | 1.301 | 0.99 | |
| 65_D | 69_T | 1.298 | 0.99 | |
| 354_G | 358_G | 1.295 | 0.99 | |
| 137_E | 178_K | 1.294 | 0.99 | |
| 5_K | 9_A | 1.289 | 0.99 | |
| 224_A | 293_F | 1.288 | 0.99 | |
| 242_L | 291_F | 1.288 | 0.99 | |
| 94_S | 129_G | 1.283 | 0.99 | |
| 133_I | 168_F | 1.282 | 0.99 | |
| 352_N | 355_S | 1.273 | 0.99 | |
| 204_Q | 318_E | 1.269 | 0.99 | |
| 116_L | 163_R | 1.265 | 0.99 | |
| 233_L | 253_I | 1.264 | 0.99 | |
| 272_D | 276_E | 1.259 | 0.99 | |
| 334_M | 339_W | 1.256 | 0.99 | |
| 200_L | 321_E | 1.256 | 0.99 | |
| 244_K | 290_E | 1.249 | 0.99 | |
| 253_I | 270_M | 1.242 | 0.98 | |
| 144_V | 160_A | 1.239 | 0.98 | |
| 52_V | 66_K | 1.236 | 0.98 | |
| 242_L | 245_N | 1.236 | 0.98 | |
| 223_I | 277_L | 1.235 | 0.98 | |
| 99_E | 103_H | 1.226 | 0.98 | |
| 10_A | 17_Y | 1.223 | 0.98 | |
| 69_T | 72_K | 1.218 | 0.98 | |
| 241_M | 292_V | 1.215 | 0.98 | |
| 279_T | 282_S | 1.212 | 0.98 | |
| 101_Y | 117_A | 1.209 | 0.98 | |
| 331_S | 335_N | 1.208 | 0.98 | |
| 168_F | 182_A | 1.205 | 0.98 | |
| 339_W | 375_W | 1.197 | 0.98 | |
| 230_Y | 274_V | 1.191 | 0.98 | |
| 223_I | 280_T | 1.188 | 0.98 | |
| 165_G | 169_R | 1.187 | 0.98 | |
| 93_F | 97_Y | 1.185 | 0.98 | |
| 73_D | 78_I | 1.181 | 0.98 | |
| 118_K | 122_D | 1.181 | 0.98 | |
| 98_K | 121_D | 1.175 | 0.98 | |
| 38_Q | 51_T | 1.171 | 0.98 | |
| 72_K | 76_V | 1.164 | 0.97 | |
| 167_V | 171_A | 1.163 | 0.97 | |
| 207_A | 211_A | 1.161 | 0.97 | |
| 236_K | 240_S | 1.139 | 0.97 | |
| 356_V | 359_I | 1.135 | 0.97 | |
| 39_L | 66_K | 1.126 | 0.97 | |
| 67_A | 71_R | 1.125 | 0.97 | |
| 123_D | 126_P | 1.116 | 0.96 | |
| 339_W | 343_A | 1.112 | 0.96 | |
| 115_E | 118_K | 1.11 | 0.96 | |
| 226_K | 273_Q | 1.105 | 0.96 | |
| 321_E | 325_G | 1.104 | 0.96 | |
| 345_E | 358_G | 1.103 | 0.96 | |
| 367_D | 370_R | 1.101 | 0.96 | |
| 68_W | 75_S | 1.101 | 0.96 | |
| 248_F | 270_M | 1.098 | 0.96 | |
| 108_W | 112_Y | 1.09 | 0.96 | |
| 332_T | 361_N | 1.089 | 0.96 | |
| 213_A | 222_L | 1.086 | 0.96 | |
| 123_D | 151_R | 1.083 | 0.96 | |
| 205_I | 333_I | 1.078 | 0.95 | |
| 36_V | 51_T | 1.07 | 0.95 | |
| 105_K | 113_A | 1.067 | 0.95 | |
| 102_E | 105_K | 1.067 | 0.95 | |
| 97_Y | 125_L | 1.065 | 0.95 | |
| 248_F | 292_V | 1.065 | 0.95 | |
| 227_V | 293_F | 1.064 | 0.95 | |
| 208_F | 225_T | 1.064 | 0.95 | |
| 16_P | 28_Y | 1.062 | 0.95 | |
| 66_K | 70_A | 1.06 | 0.95 | |
| 138_P | 173_V | 1.05 | 0.94 | |
| 227_V | 278_L | 1.046 | 0.94 | |
| 332_T | 363_A | 1.037 | 0.94 | |
| 36_V | 54_K | 1.037 | 0.94 | |
| 274_V | 277_L | 1.034 | 0.94 | |
| 28_Y | 38_Q | 1.033 | 0.94 | |
| 120_F | 167_V | 1.03 | 0.94 | |
| 100_W | 166_E | 1.027 | 0.94 | |
| 213_A | 226_K | 1.027 | 0.94 | |
| 272_D | 374_Q | 1.024 | 0.93 | |
| 52_V | 55_Y | 1.022 | 0.93 | |
| 105_K | 117_A | 1.021 | 0.93 | |
| 124_I | 164_C | 1.018 | 0.93 | |
| 18_R | 26_Y | 1.017 | 0.93 | |
| 120_F | 124_I | 1.014 | 0.93 | |
| 345_E | 356_V | 1.011 | 0.93 | |
| 93_F | 128_I | 1.008 | 0.93 | |
| 355_S | 358_G | 1.006 | 0.93 | |
| 231_T | 271_S | 1.004 | 0.93 | |
| 142_L | 174_T | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1z1bA | 2 | 0.8701 | 100 | 0.376 | Contact Map | 0.604 |
| 1a0pA | 1 | 0.7065 | 100 | 0.44 | Contact Map | 0.557 |
| 1z19A | 2 | 0.6987 | 100 | 0.443 | Contact Map | 0.602 |
| 2a3vA | 4 | 0.7091 | 100 | 0.451 | Contact Map | 0.732 |
| 4a8eA | 1 | 0.7143 | 100 | 0.492 | Contact Map | 0.697 |
| 1xo0A | 2 | 0.7273 | 100 | 0.494 | Contact Map | 0.502 |
| 4e0gA | 1 | 0.9195 | 100 | 0.56 | Contact Map | 0.388 |
| 3nkhA | 2 | 0.5273 | 100 | 0.579 | Contact Map | 0.796 |
| 1ae9A | 2 | 0.4286 | 100 | 0.634 | Contact Map | 0.595 |
| 1aihA | 4 | 0.4364 | 99.9 | 0.646 | Contact Map | 0.74 |
Sequence Conservation (Image Generated using WebLogo v3)