May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
RDGC - Recombination-associated protein RdgC
UniProt: P36767 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12158
Length: 303 (301)
Sequences: 342
Seq/Len: 1.14
RDGC
Paralog alert: 0.07 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
84_L 107_L 2.742 1.00
128_M 150_T 2.739 1.00
45_W 157_S 2.569 1.00
77_S 80_I 2.216 0.98
172_I 176_L 2.122 0.98
196_E 208_R 2.088 0.97
63_Q 129_W 2.036 0.97
73_K 121_S 1.94 0.96
131_D 134_N 1.876 0.94
63_Q 283_T 1.869 0.94
66_I 128_M 1.86 0.94
175_T 297_L 1.809 0.93
67_C 127_M 1.725 0.91
81_K 85_E 1.71 0.90
79_V 120_F 1.704 0.90
129_W 283_T 1.702 0.90
243_V 252_R 1.694 0.89
84_L 111_V 1.681 0.89
3_W 282_M 1.629 0.87
212_Q 227_K 1.613 0.86
97_R 103_E 1.592 0.85
3_W 252_R 1.568 0.84
87_K 110_E 1.541 0.82
32_F 69_R 1.535 0.82
172_I 248_G 1.532 0.82
79_V 108_K 1.524 0.82
148_E 155_R 1.522 0.81
244_M 297_L 1.479 0.79
212_Q 229_V 1.472 0.78
270_D 273_Q 1.467 0.78
65_V 281_L 1.445 0.76
91_L 99_L 1.44 0.76
4_F 282_M 1.436 0.76
136_L 290_I 1.414 0.74
148_E 151_L 1.409 0.74
56_L 80_I 1.401 0.73
62_G 133_V 1.393 0.73
87_K 111_V 1.364 0.70
45_W 275_F 1.363 0.70
238_Q 258_E 1.346 0.69
82_Q 123_F 1.345 0.69
126_T 140_D 1.341 0.69
234_L 242_F 1.332 0.68
218_E 253_L 1.33 0.68
227_K 230_T 1.329 0.68
66_I 150_T 1.327 0.67
5_K 39_D 1.326 0.67
110_E 114_S 1.311 0.66
222_H 285_E 1.31 0.66
56_L 293_L 1.293 0.64
166_L 257_D 1.29 0.64
87_K 114_S 1.286 0.64
222_H 227_K 1.275 0.63
71_E 194_E 1.274 0.63
194_E 208_R 1.264 0.62
61_N 133_V 1.256 0.61
242_F 257_D 1.245 0.60
75_L 79_V 1.24 0.60
67_C 125_Q 1.232 0.59
195_A 204_G 1.228 0.59
48_P 300_E 1.227 0.58
243_V 286_L 1.224 0.58
292_N 296_G 1.219 0.58
98_K 300_E 1.219 0.58
58_H 276_D 1.217 0.58
244_M 250_L 1.213 0.57
87_K 91_L 1.208 0.57
190_Q 238_Q 1.207 0.57
39_D 42_K 1.207 0.57
194_E 210_K 1.2 0.56
2_L 7_L 1.198 0.56
189_F 296_G 1.196 0.56
22_E 25_K 1.185 0.54
217_E 230_T 1.182 0.54
79_V 115_L 1.172 0.53
42_K 73_K 1.169 0.53
98_K 109_D 1.168 0.53
11_R 27_L 1.167 0.53
60_A 289_L 1.164 0.52
209_A 219_I 1.158 0.52
77_S 191_L 1.157 0.52
160_S 165_P 1.155 0.52
43_M 68_A 1.142 0.50
73_K 80_I 1.14 0.50
196_E 231_K 1.139 0.50
129_W 138_M 1.138 0.50
263_N 278_D 1.132 0.49
11_R 298_G 1.131 0.49
88_I 111_V 1.13 0.49
151_L 163_V 1.126 0.49
188_G 292_N 1.117 0.48
90_K 94_E 1.114 0.48
122_R 234_L 1.107 0.47
242_F 284_G 1.106 0.47
168_M 192_L 1.096 0.46
250_L 289_L 1.092 0.46
153_L 157_S 1.091 0.45
217_E 259_L 1.091 0.45
98_K 286_L 1.088 0.45
106_S 110_E 1.084 0.45
223_I 278_D 1.082 0.45
149_D 203_D 1.082 0.45
72_E 151_L 1.08 0.44
195_A 263_N 1.079 0.44
74_I 114_S 1.078 0.44
3_W 75_L 1.071 0.44
183_G 220_T 1.069 0.43
18_L 207_I 1.067 0.43
117_P 196_E 1.066 0.43
5_K 199_S 1.057 0.42
296_G 300_E 1.056 0.42
239_R 285_E 1.054 0.42
5_K 171_P 1.052 0.42
176_L 190_Q 1.051 0.42
9_V 166_L 1.05 0.42
187_Q 261_D 1.047 0.41
236_W 259_L 1.046 0.41
68_A 153_L 1.044 0.41
254_K 261_D 1.042 0.41
157_S 169_E 1.039 0.41
45_W 129_W 1.037 0.40
107_L 238_Q 1.037 0.40
189_F 234_L 1.03 0.40
217_E 225_A 1.03 0.40
195_A 281_L 1.028 0.40
30_M 253_L 1.026 0.39
153_L 274_R 1.026 0.39
206_V 231_K 1.025 0.39
95_Q 175_T 1.024 0.39
192_L 256_C 1.022 0.39
25_K 86_A 1.018 0.39
177_T 229_V 1.017 0.39
96_A 238_Q 1.016 0.38
155_R 160_S 1.015 0.38
233_A 243_V 1.012 0.38
185_A 191_L 1.011 0.38
259_L 281_L 1.01 0.38
274_R 278_D 1.006 0.38
89_A 157_S 1.003 0.37
84_L 170_N 1.001 0.37
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2owlA211000.087Contact Map0.496
2owyA20.99671000.091Contact Map0.492
2zc2A20.224415.60.975Contact Map0.391
1mu5A10.35978.90.978Contact Map0.134
4dzoA20.37626.80.979Contact Map0.098
2lw7A10.534760.979Contact Map0.296
2g3wA20.19145.80.98Contact Map0.235
2ot9A10.18155.70.98Contact Map0.292
1dbuA10.31024.20.981Contact Map0.25
2zbkB40.54463.50.982Contact Map0.123
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 0.5651 seconds.