| UniProt: | P33997 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12112 | ||
| Length: | 70 (60) | ||
| Sequences: | 621 | ||
| Seq/Len: | 10.35 |
| ALPA
Paralog alert: 0.55 [within 20: 0.04] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 9_I | 53_G | 5.011 | 1.00 | |
| 30_L | 44_K | 3.162 | 1.00 | |
| 9_I | 63_L | 2.506 | 1.00 | |
| 18_K | 60_D | 2.339 | 1.00 | |
| 29_W | 40_T | 2.079 | 1.00 | |
| 55_I | 58_E | 1.984 | 1.00 | |
| 27_Y | 30_L | 1.974 | 1.00 | |
| 16_I | 26_I | 1.872 | 1.00 | |
| 12_L | 16_I | 1.824 | 1.00 | |
| 8_R | 56_E | 1.68 | 1.00 | |
| 11_R | 20_G | 1.657 | 1.00 | |
| 48_G | 51_S | 1.619 | 1.00 | |
| 25_T | 29_W | 1.47 | 1.00 | |
| 14_A | 17_Q | 1.382 | 0.99 | |
| 11_R | 53_G | 1.378 | 0.99 | |
| 45_R | 55_I | 1.311 | 0.99 | |
| 11_R | 51_S | 1.31 | 0.99 | |
| 21_M | 29_W | 1.265 | 0.99 | |
| 10_L | 14_A | 1.241 | 0.98 | |
| 18_K | 56_E | 1.191 | 0.98 | |
| 61_E | 65_Q | 1.179 | 0.98 | |
| 7_V | 57_A | 1.15 | 0.97 | |
| 16_I | 22_A | 1.127 | 0.97 | |
| 55_I | 67_C | 1.124 | 0.97 | |
| 10_L | 56_E | 1.096 | 0.96 | |
| 24_A | 28_D | 1.088 | 0.96 | |
| 15_V | 26_I | 1.074 | 0.95 | |
| 27_Y | 54_W | 1.044 | 0.94 | |
| 10_L | 15_V | 1.039 | 0.94 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1z4hA | 1 | 0.9 | 99.4 | 0.391 | Contact Map | 0.502 |
| 1y6uA | 1 | 0.8857 | 98.9 | 0.507 | Contact Map | 0.584 |
| 4j2nA | 5 | 0.8286 | 98.5 | 0.573 | Contact Map | 0.754 |
| 1j9iA | 2 | 0.7857 | 98.2 | 0.604 | Contact Map | 0.705 |
| 2kfsA | 1 | 0.8857 | 97.1 | 0.683 | Contact Map | 0.571 |
| 2og0A | 2 | 0.7 | 96.6 | 0.703 | Contact Map | 0.747 |
| 2jmlA | 1 | 0.8571 | 93.6 | 0.757 | Contact Map | 0.455 |
| 2kvvA | 1 | 0.9143 | 90.7 | 0.777 | Contact Map | 0.661 |
| 2zhgA | 1 | 0.9 | 90.7 | 0.777 | Contact Map | 0.626 |
| 2ao9A | 9 | 0.9 | 86.8 | 0.792 | Contact Map | 0.581 |
Sequence Conservation (Image Generated using WebLogo v3)