| UniProt: | P33941 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12070 | ||
| Length: | 547 (530) | ||
| Sequences: | 15540 | ||
| Seq/Len: | 29.32 |
| YOJI
Paralog alert: 0.94 [within 20: 0.56] - ratio of genomes with paralogs Cluster includes: CYDC CYDD MDLA MDLB MSBA YDDA YOJI |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 327_N | 341_P | 5.61 | 1.00 | |
| 324_E | 345_T | 4.982 | 1.00 | |
| 350_E | 518_R | 4.876 | 1.00 | |
| 347_K | 350_E | 4.834 | 1.00 | |
| 326_R | 379_E | 4.651 | 1.00 | |
| 411_Q | 415_P | 4.281 | 1.00 | |
| 518_R | 530_L | 4.278 | 1.00 | |
| 326_R | 381_L | 4.273 | 1.00 | |
| 414_G | 422_P | 4.114 | 1.00 | |
| 379_E | 386_P | 3.941 | 1.00 | |
| 430_A | 435_A | 3.918 | 1.00 | |
| 340_G | 526_Q | 3.773 | 1.00 | |
| 421_N | 424_L | 3.583 | 1.00 | |
| 435_A | 439_E | 3.503 | 1.00 | |
| 329_T | 341_P | 3.432 | 1.00 | |
| 322_T | 345_T | 3.428 | 1.00 | |
| 422_P | 426_E | 3.162 | 1.00 | |
| 325_L | 328_V | 3.128 | 1.00 | |
| 366_A | 506_I | 3.122 | 1.00 | |
| 400_S | 468_R | 3.036 | 1.00 | |
| 414_G | 425_V | 3.026 | 1.00 | |
| 324_E | 381_L | 2.952 | 1.00 | |
| 435_A | 445_I | 2.942 | 1.00 | |
| 371_G | 374_Q | 2.926 | 1.00 | |
| 344_L | 520_L | 2.903 | 1.00 | |
| 398_L | 469_D | 2.787 | 1.00 | |
| 427_K | 431_Q | 2.781 | 1.00 | |
| 434_M | 437_K | 2.715 | 1.00 | |
| 426_E | 430_A | 2.666 | 1.00 | |
| 391_Q | 394_D | 2.657 | 1.00 | |
| 366_A | 472_L | 2.645 | 1.00 | |
| 337_F | 340_G | 2.627 | 1.00 | |
| 329_T | 377_S | 2.558 | 1.00 | |
| 435_A | 444_R | 2.545 | 1.00 | |
| 346_I | 352_L | 2.496 | 1.00 | |
| 322_T | 347_K | 2.462 | 1.00 | |
| 140_A | 144_M | 2.442 | 1.00 | |
| 374_Q | 388_S | 2.401 | 1.00 | |
| 325_L | 344_L | 2.394 | 1.00 | |
| 426_E | 435_A | 2.372 | 1.00 | |
| 351_L | 516_A | 2.344 | 1.00 | |
| 520_L | 530_L | 2.333 | 1.00 | |
| 322_T | 348_R | 2.332 | 1.00 | |
| 327_N | 343_N | 2.27 | 1.00 | |
| 442_N | 446_V | 2.196 | 1.00 | |
| 346_I | 504_F | 2.154 | 1.00 | |
| 7_V | 86_E | 2.15 | 1.00 | |
| 352_L | 518_R | 2.064 | 1.00 | |
| 414_G | 446_V | 2.059 | 1.00 | |
| 427_K | 430_A | 2.045 | 1.00 | |
| 429_L | 438_L | 2.035 | 1.00 | |
| 489_Y | 492_L | 2.027 | 1.00 | |
| 331_A | 337_F | 2.027 | 1.00 | |
| 323_L | 504_F | 2.025 | 1.00 | |
| 426_E | 439_E | 2.023 | 1.00 | |
| 467_E | 501_K | 2.007 | 1.00 | |
| 37_N | 41_I | 1.985 | 1.00 | |
| 429_L | 445_I | 1.985 | 1.00 | |
| 329_T | 337_F | 1.979 | 1.00 | |
| 428_W | 432_L | 1.965 | 1.00 | |
| 414_G | 445_I | 1.959 | 1.00 | |
| 339_V | 342_I | 1.942 | 1.00 | |
| 442_N | 445_I | 1.938 | 1.00 | |
| 444_R | 447_N | 1.927 | 1.00 | |
| 331_A | 376_Q | 1.927 | 1.00 | |
| 418_K | 424_L | 1.904 | 1.00 | |
| 443_G | 447_N | 1.894 | 1.00 | |
| 354_L | 365_L | 1.881 | 1.00 | |
| 423_Q | 426_E | 1.852 | 1.00 | |
| 443_G | 446_V | 1.829 | 1.00 | |
| 330_F | 364_T | 1.826 | 1.00 | |
| 365_L | 522_M | 1.813 | 1.00 | |
| 424_L | 427_K | 1.784 | 1.00 | |
| 33_I | 37_N | 1.779 | 1.00 | |
| 375_P | 387_V | 1.778 | 1.00 | |
| 520_L | 527_L | 1.767 | 1.00 | |
| 9_R | 12_R | 1.765 | 1.00 | |
| 354_L | 520_L | 1.755 | 1.00 | |
| 358_N | 484_F | 1.753 | 1.00 | |
| 386_P | 389_G | 1.741 | 1.00 | |
| 436_H | 439_E | 1.739 | 1.00 | |
| 11_Y | 82_R | 1.728 | 1.00 | |
| 143_W | 147_G | 1.713 | 1.00 | |
| 429_L | 435_A | 1.685 | 1.00 | |
| 351_L | 505_A | 1.673 | 1.00 | |
| 114_D | 298_K | 1.672 | 1.00 | |
| 413_L | 458_V | 1.663 | 1.00 | |
| 321_Q | 383_D | 1.663 | 1.00 | |
| 441_S | 444_R | 1.659 | 1.00 | |
| 38_Q | 42_E | 1.643 | 1.00 | |
| 310_E | 391_Q | 1.632 | 1.00 | |
| 507_S | 512_Y | 1.623 | 1.00 | |
| 34_A | 37_N | 1.623 | 1.00 | |
| 485_R | 509_D | 1.614 | 1.00 | |
| 143_W | 150_L | 1.613 | 1.00 | |
| 420_A | 465_A | 1.605 | 1.00 | |
| 492_L | 495_L | 1.59 | 1.00 | |
| 422_P | 425_V | 1.587 | 1.00 | |
| 352_L | 520_L | 1.578 | 1.00 | |
| 380_I | 387_V | 1.57 | 1.00 | |
| 420_A | 424_L | 1.547 | 1.00 | |
| 300_N | 303_A | 1.545 | 1.00 | |
| 426_E | 429_L | 1.542 | 1.00 | |
| 341_P | 526_Q | 1.538 | 1.00 | |
| 523_R | 528_S | 1.523 | 1.00 | |
| 433_K | 487_E | 1.516 | 1.00 | |
| 181_T | 220_E | 1.508 | 1.00 | |
| 344_L | 365_L | 1.507 | 1.00 | |
| 34_A | 38_Q | 1.507 | 1.00 | |
| 149_M | 268_Y | 1.5 | 1.00 | |
| 382_L | 470_I | 1.495 | 1.00 | |
| 322_T | 383_D | 1.49 | 1.00 | |
| 385_K | 389_G | 1.485 | 1.00 | |
| 90_R | 94_T | 1.484 | 1.00 | |
| 400_S | 463_A | 1.471 | 1.00 | |
| 350_E | 517_D | 1.468 | 1.00 | |
| 424_L | 467_E | 1.458 | 1.00 | |
| 434_M | 438_L | 1.457 | 1.00 | |
| 100_E | 373_Y | 1.452 | 1.00 | |
| 325_L | 369_L | 1.441 | 1.00 | |
| 357_G | 523_R | 1.438 | 1.00 | |
| 429_L | 444_R | 1.425 | 1.00 | |
| 368_L | 380_I | 1.417 | 1.00 | |
| 324_E | 384_G | 1.412 | 1.00 | |
| 431_Q | 464_L | 1.41 | 1.00 | |
| 428_W | 464_L | 1.408 | 1.00 | |
| 330_F | 373_Y | 1.389 | 0.99 | |
| 370_T | 401_A | 1.382 | 0.99 | |
| 342_I | 365_L | 1.381 | 0.99 | |
| 34_A | 42_E | 1.37 | 0.99 | |
| 147_G | 151_L | 1.365 | 0.99 | |
| 507_S | 513_F | 1.363 | 0.99 | |
| 353_F | 516_A | 1.346 | 0.99 | |
| 170_R | 173_K | 1.331 | 0.99 | |
| 489_Y | 493_L | 1.329 | 0.99 | |
| 480_Q | 488_F | 1.329 | 0.99 | |
| 358_N | 457_R | 1.324 | 0.99 | |
| 441_S | 447_N | 1.321 | 0.99 | |
| 162_W | 166_V | 1.318 | 0.99 | |
| 329_T | 340_G | 1.318 | 0.99 | |
| 452_K | 457_R | 1.314 | 0.99 | |
| 347_K | 518_R | 1.314 | 0.99 | |
| 90_R | 93_D | 1.298 | 0.99 | |
| 429_L | 434_M | 1.295 | 0.99 | |
| 176_A | 297_N | 1.294 | 0.99 | |
| 117_N | 295_A | 1.292 | 0.99 | |
| 375_P | 380_I | 1.29 | 0.99 | |
| 369_L | 504_F | 1.287 | 0.99 | |
| 142_L | 268_Y | 1.283 | 0.99 | |
| 195_G | 407_W | 1.276 | 0.99 | |
| 311_F | 389_G | 1.272 | 0.99 | |
| 402_V | 460_L | 1.266 | 0.99 | |
| 214_Y | 218_A | 1.255 | 0.99 | |
| 424_L | 465_A | 1.25 | 0.99 | |
| 353_F | 513_F | 1.247 | 0.99 | |
| 10_Q | 82_R | 1.244 | 0.98 | |
| 475_E | 508_H | 1.239 | 0.98 | |
| 181_T | 184_K | 1.238 | 0.98 | |
| 351_L | 503_I | 1.235 | 0.98 | |
| 342_I | 527_L | 1.233 | 0.98 | |
| 87_F | 302_F | 1.225 | 0.98 | |
| 100_E | 367_M | 1.222 | 0.98 | |
| 522_M | 527_L | 1.218 | 0.98 | |
| 184_K | 220_E | 1.215 | 0.98 | |
| 322_T | 384_G | 1.209 | 0.98 | |
| 311_F | 314_P | 1.207 | 0.98 | |
| 323_L | 382_L | 1.197 | 0.98 | |
| 325_L | 365_L | 1.193 | 0.98 | |
| 212_N | 216_P | 1.189 | 0.98 | |
| 103_G | 106_S | 1.187 | 0.98 | |
| 102_L | 106_S | 1.186 | 0.98 | |
| 509_D | 512_Y | 1.182 | 0.98 | |
| 74_T | 78_H | 1.181 | 0.98 | |
| 252_W | 256_S | 1.18 | 0.98 | |
| 16_I | 20_A | 1.179 | 0.98 | |
| 263_N | 267_T | 1.175 | 0.98 | |
| 320_W | 383_D | 1.17 | 0.97 | |
| 519_L | 533_E | 1.169 | 0.97 | |
| 206_A | 209_V | 1.169 | 0.97 | |
| 326_R | 343_N | 1.156 | 0.97 | |
| 385_K | 390_E | 1.155 | 0.97 | |
| 110_G | 301_K | 1.155 | 0.97 | |
| 412_L | 415_P | 1.145 | 0.97 | |
| 38_Q | 41_I | 1.144 | 0.97 | |
| 327_N | 377_S | 1.131 | 0.97 | |
| 296_F | 300_N | 1.123 | 0.97 | |
| 414_G | 426_E | 1.12 | 0.96 | |
| 352_L | 504_F | 1.113 | 0.96 | |
| 85_S | 89_K | 1.109 | 0.96 | |
| 95_H | 307_F | 1.101 | 0.96 | |
| 440_L | 454_Q | 1.092 | 0.96 | |
| 142_L | 150_L | 1.087 | 0.96 | |
| 324_E | 343_N | 1.087 | 0.96 | |
| 402_V | 463_A | 1.079 | 0.95 | |
| 254_A | 257_L | 1.078 | 0.95 | |
| 348_R | 469_D | 1.071 | 0.95 | |
| 394_D | 397_K | 1.071 | 0.95 | |
| 330_F | 368_L | 1.07 | 0.95 | |
| 346_I | 502_T | 1.067 | 0.95 | |
| 435_A | 438_L | 1.06 | 0.95 | |
| 433_K | 484_F | 1.059 | 0.95 | |
| 360_S | 522_M | 1.058 | 0.95 | |
| 250_V | 254_A | 1.057 | 0.95 | |
| 442_N | 447_N | 1.056 | 0.95 | |
| 211_N | 215_I | 1.054 | 0.95 | |
| 145_L | 264_V | 1.053 | 0.95 | |
| 208_Y | 212_N | 1.052 | 0.95 | |
| 521_E | 529_E | 1.05 | 0.94 | |
| 12_R | 16_I | 1.05 | 0.94 | |
| 210_F | 213_L | 1.046 | 0.94 | |
| 52_P | 56_G | 1.045 | 0.94 | |
| 323_L | 369_L | 1.044 | 0.94 | |
| 432_L | 457_R | 1.041 | 0.94 | |
| 324_E | 379_E | 1.04 | 0.94 | |
| 437_K | 454_Q | 1.031 | 0.94 | |
| 151_L | 155_I | 1.026 | 0.94 | |
| 421_N | 465_A | 1.025 | 0.93 | |
| 406_V | 459_A | 1.024 | 0.93 | |
| 90_R | 306_P | 1.023 | 0.93 | |
| 423_Q | 427_K | 1.019 | 0.93 | |
| 468_R | 501_K | 1.019 | 0.93 | |
| 86_E | 90_R | 1.018 | 0.93 | |
| 323_L | 470_I | 1.018 | 0.93 | |
| 431_Q | 495_L | 1.017 | 0.93 | |
| 222_R | 226_I | 1.017 | 0.93 | |
| 146_S | 150_L | 1.014 | 0.93 | |
| 321_Q | 348_R | 1.013 | 0.93 | |
| 379_E | 388_S | 1.013 | 0.93 | |
| 348_R | 383_D | 1.011 | 0.93 | |
| 441_S | 445_I | 1.004 | 0.93 | |
| 30_I | 137_G | 1.003 | 0.93 | |
| 331_A | 338_S | 1.003 | 0.93 | |
| 486_R | 490_Q | 1.002 | 0.92 | |
| 427_K | 467_E | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3qf4B | 1 | 0.9927 | 100 | 0.189 | Contact Map | 0.707 |
| 3b5xA | 2 | 0.9909 | 100 | 0.194 | Contact Map | 0.127 |
| 3b60A | 4 | 0.9909 | 100 | 0.194 | Contact Map | 0.766 |
| 4a82A | 4 | 0.9909 | 100 | 0.196 | Contact Map | 0.083 |
| 4f4cA | 1 | 0.9927 | 100 | 0.197 | Contact Map | 0.734 |
| 3qf4A | 1 | 0.9927 | 100 | 0.201 | Contact Map | 0.738 |
| 2yl4A | 1 | 0.9927 | 100 | 0.207 | Contact Map | 0.71 |
| 3g5uA | 2 | 0.9927 | 100 | 0.21 | Contact Map | 0.701 |
| 3nh6A | 1 | 0.5009 | 100 | 0.457 | Contact Map | 0.795 |
| 3vx4A | 2 | 0.4644 | 100 | 0.511 | Contact Map | 0.859 |
Sequence Conservation (Image Generated using WebLogo v3)