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OPENSEQ.org
YEHC - Uncharacterized fimbrial chaperone YehC
UniProt: P33342 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11989
Length: 239 (209)
Sequences: 1344
Seq/Len: 6.43
YEHC
Paralog alert: 0.90 [within 20: 0.52] - ratio of genomes with paralogs
Cluster includes: ECPD ELFD FIMC SFMC YBGP YCBF YEHC YFCS YHCA YQIH YRAI
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
111_L 119_F 2.849 1.00
37_I 147_I 2.84 1.00
185_W 206_A 2.812 1.00
187_T 204_M 2.743 1.00
118_I 204_M 2.676 1.00
206_A 209_E 2.662 1.00
150_F 204_M 2.467 1.00
45_P 48_N 2.456 1.00
115_K 208_L 2.44 1.00
168_L 179_K 2.351 1.00
179_K 210_S 2.32 1.00
69_I 149_L 2.195 1.00
42_I 121_L 2.15 1.00
42_I 104_I 2.124 1.00
42_I 51_V 2.089 1.00
68_W 122_N 2.078 1.00
63_S 125_D 2.05 1.00
70_D 146_R 2.045 1.00
112_P 117_S 2.034 1.00
178_I 213_V 2.019 1.00
62_S 93_K 1.942 1.00
46_A 113_T 1.938 1.00
62_S 95_G 1.935 1.00
122_N 146_R 1.839 1.00
160_N 163_T 1.808 1.00
156_I 184_N 1.674 1.00
169_V 178_I 1.667 1.00
47_E 154_A 1.66 1.00
124_L 144_Q 1.641 1.00
118_I 187_T 1.64 1.00
95_G 98_S 1.635 1.00
85_F 104_I 1.622 1.00
112_P 115_K 1.618 1.00
172_S 177_V 1.611 1.00
177_V 212_S 1.61 1.00
166_K 182_S 1.577 0.99
70_D 122_N 1.565 0.99
162_A 165_K 1.528 0.99
229_D 235_I 1.482 0.99
194_N 197_K 1.458 0.99
163_T 186_V 1.45 0.99
104_I 149_L 1.443 0.99
167_L 178_I 1.407 0.99
229_D 233_N 1.381 0.98
186_V 227_I 1.381 0.98
87_L 102_V 1.376 0.98
37_I 123_V 1.372 0.98
45_P 51_V 1.366 0.98
205_I 211_Q 1.363 0.98
170_N 177_V 1.362 0.98
106_I 109_N 1.328 0.98
150_F 185_W 1.323 0.98
177_V 210_S 1.322 0.98
118_I 150_F 1.31 0.97
60_N 97_N 1.305 0.97
36_V 39_G 1.296 0.97
42_I 147_I 1.293 0.97
54_Q 99_G 1.27 0.97
187_T 227_I 1.268 0.97
70_D 120_Y 1.258 0.96
37_I 53_V 1.247 0.96
87_L 104_I 1.247 0.96
35_I 94_I 1.241 0.96
55_L 65_L 1.24 0.96
223_W 227_I 1.217 0.95
158_P 162_A 1.208 0.95
65_L 92_A 1.207 0.95
120_Y 124_L 1.186 0.95
170_N 179_K 1.179 0.94
44_Y 51_V 1.178 0.94
62_S 128_P 1.174 0.94
126_I 143_M 1.169 0.94
102_V 121_L 1.166 0.94
87_L 121_L 1.159 0.94
175_G 212_S 1.156 0.94
71_D 79_E 1.151 0.93
169_V 191_V 1.149 0.93
34_G 125_D 1.148 0.93
172_S 175_G 1.13 0.93
100_Q 124_L 1.129 0.93
72_G 78_P 1.121 0.92
102_V 123_V 1.104 0.91
76_L 81_I 1.097 0.91
188_I 205_I 1.093 0.91
167_L 188_I 1.092 0.91
227_I 235_I 1.08 0.90
205_I 209_E 1.06 0.89
106_I 151_Y 1.057 0.89
67_A 102_V 1.054 0.89
116_E 152_R 1.044 0.88
137_N 146_R 1.04 0.88
164_F 225_L 1.039 0.88
106_I 110_K 1.037 0.88
159_V 162_A 1.016 0.86
81_I 84_P 1.014 0.86
68_W 146_R 1.012 0.86
169_V 204_M 1.003 0.85
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4djmA80.92051000.23Contact Map0.826
1klfA80.83261000.237Contact Map0.796
1l4iA20.83261000.242Contact Map0.795
2co7B10.8871000.242Contact Map0.753
4ay0A20.88281000.253Contact Map0.784
2xg5A10.82851000.256Contact Map0.813
3gfuC20.80751000.263Contact Map0.714
3q48A20.96651000.266Contact Map0.81
1mspA20.472856.20.95Contact Map0.57
1z9lA10.485420.60.961Contact Map0.689
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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