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OPENSEQ.org
STFE - Putative protein StfE (Fragment)
UniProt: P33227 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11818
Length: 166 (166)
Sequences: 217
Seq/Len: 1.31
STFE
Paralog alert: 0.22 [within 20: 0.05] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
83_E 152_T 2.449 1.00
38_E 41_E 2.088 0.98
36_A 41_E 1.969 0.97
147_A 152_T 1.964 0.97
28_K 64_D 1.938 0.97
83_E 147_A 1.914 0.96
80_Y 83_E 1.833 0.95
141_S 144_G 1.796 0.94
85_H 152_T 1.739 0.93
84_D 87_H 1.733 0.93
80_Y 84_D 1.603 0.88
35_S 49_N 1.576 0.87
80_Y 151_E 1.565 0.87
35_S 38_E 1.547 0.86
82_T 152_T 1.487 0.83
142_V 147_A 1.475 0.82
70_T 73_S 1.464 0.81
35_S 44_K 1.46 0.81
58_F 154_P 1.442 0.80
19_S 36_A 1.436 0.79
87_H 146_G 1.429 0.79
19_S 44_K 1.428 0.79
41_E 44_K 1.393 0.77
81_A 84_D 1.389 0.76
80_Y 85_H 1.382 0.76
79_G 152_T 1.374 0.75
57_E 155_R 1.372 0.75
16_P 161_Y 1.355 0.74
36_A 49_N 1.353 0.74
81_A 149_A 1.339 0.72
79_G 83_E 1.338 0.72
80_Y 152_T 1.331 0.72
29_C 54_L 1.308 0.70
32_A 35_S 1.307 0.70
38_E 49_N 1.305 0.70
36_A 44_K 1.298 0.69
37_E 48_T 1.297 0.69
41_E 49_N 1.275 0.67
37_E 49_N 1.271 0.67
83_E 87_H 1.266 0.66
54_L 57_E 1.26 0.66
84_D 152_T 1.246 0.64
44_K 50_K 1.243 0.64
34_F 47_P 1.232 0.63
87_H 152_T 1.217 0.62
3_L 6_G 1.209 0.61
14_P 159_F 1.2 0.60
7_S 15_V 1.187 0.59
7_S 11_V 1.183 0.59
85_H 146_G 1.18 0.58
82_T 85_H 1.179 0.58
16_P 162_I 1.178 0.58
16_P 29_C 1.177 0.58
101_I 104_Y 1.167 0.57
85_H 151_E 1.148 0.55
47_P 75_L 1.147 0.55
19_S 50_K 1.14 0.54
73_S 76_S 1.139 0.54
81_A 85_H 1.136 0.54
19_S 41_E 1.131 0.53
6_G 9_L 1.127 0.53
141_S 146_G 1.126 0.53
140_Q 146_G 1.119 0.52
34_F 75_L 1.115 0.52
38_E 44_K 1.114 0.52
46_Y 162_I 1.105 0.51
75_L 165_A 1.093 0.50
143_D 146_G 1.076 0.48
38_E 50_K 1.072 0.48
9_L 15_V 1.066 0.47
54_L 61_G 1.06 0.46
16_P 46_Y 1.052 0.46
46_Y 61_G 1.05 0.45
16_P 54_L 1.045 0.45
29_C 161_Y 1.04 0.44
34_F 43_A 1.037 0.44
140_Q 145_L 1.034 0.44
14_P 18_P 1.026 0.43
82_T 147_A 1.019 0.42
142_V 146_G 1.019 0.42
28_K 32_A 1.007 0.41
34_F 162_I 1.003 0.41
81_A 151_E 1.003 0.41
43_A 47_P 1.001 0.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2xgfA30.96391000.539Contact Map0.309
1pdiA180.93371000.542Contact Map0.046
1ocyA10.93981000.542Contact Map0.191
1h6wA10.379599.10.823Contact Map0.118
2fkkA10.909663.10.943Contact Map0.145
2fl8A180.873521.70.957Contact Map0.009
1xknA10.4884.70.968Contact Map0.149
3h7cX10.5122.30.973Contact Map0.219
2zciA40.47592.10.973Contact Map0.291
1p4cA10.463920.974Contact Map0.025
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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