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OPENSEQ.org

YEED - UPF0033 protein YeeD
UniProt: P33014 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11894
Length: 75 (73)
Sequences: 1279
Seq/Len: 17.52

YEED
Paralog alert: 0.51 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: TUSA YEDF YEED
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
56_A 73_Q 3.333 1.00
28_V 31_D 2.673 1.00
3_I 31_D 2.383 1.00
9_V 67_A 2.354 1.00
9_V 36_E 2.249 1.00
34_V 69_S 2.171 1.00
5_K 34_V 1.952 1.00
32_E 58_T 1.846 1.00
27_M 33_L 1.732 1.00
20_A 46_I 1.582 1.00
61_Q 69_S 1.539 1.00
39_C 45_A 1.515 1.00
32_E 71_T 1.483 1.00
50_A 72_V 1.463 1.00
4_K 23_A 1.456 1.00
8_V 37_F 1.338 0.99
6_L 33_L 1.33 0.99
35_I 46_I 1.33 0.99
20_A 33_L 1.289 0.99
9_V 38_D 1.289 0.99
15_F 19_E 1.284 0.99
11_Q 15_F 1.262 0.99
20_A 35_I 1.258 0.99
23_A 26_E 1.251 0.99
36_E 69_S 1.228 0.98
29_S 75_A 1.212 0.98
10_T 38_D 1.201 0.98
17_L 49_W 1.195 0.98
5_K 36_E 1.142 0.97
34_V 71_T 1.114 0.96
42_A 70_I 1.112 0.96
50_A 57_I 1.09 0.96
11_Q 19_E 1.077 0.95
38_D 41_Q 1.072 0.95
32_E 73_Q 1.068 0.95
43_T 60_Y 1.059 0.95
27_M 30_G 1.055 0.95
62_Q 65_D 1.041 0.94
21_K 25_A 1.03 0.94
24_L 49_W 1.026 0.94
18_I 49_W 1.026 0.94
15_F 18_I 1.012 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1jdqA1199.80.096Contact Map0.387
1je3A10.973399.80.12Contact Map0.406
3hz7A10.9699.80.133Contact Map0.728
3lvjC20.986799.80.136Contact Map0.82
1pavA10.986799.80.145Contact Map0.636
2lxrA10.933399.70.215Contact Map0.43
1okgA10.7298.10.593Contact Map0.177
2qifA20.786747.60.838Contact Map0.346
2l3mA10.7733470.839Contact Map0.172
1yg0A10.7645.70.84Contact Map0.18

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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