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OPENSEQ.org
YBIC - Uncharacterized oxidoreductase YbiC
UniProt: P30178 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11581
Length: 361 (344)
Sequences: 893
Seq/Len: 2.60
YBIC
Paralog alert: 0.56 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: ALLD DLGD YBIC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
85_G 93_A 3.924 1.00
128_A 166_C 3.765 1.00
322_E 326_Q 3.269 1.00
299_K 314_E 3.12 1.00
155_G 301_S 3.089 1.00
72_K 86_D 3.028 1.00
206_L 220_M 2.892 1.00
303_H 309_I 2.542 1.00
13_H 35_D 2.494 1.00
98_M 131_C 2.424 1.00
66_Q 86_D 2.351 1.00
216_N 219_V 2.332 1.00
78_G 108_H 2.31 1.00
200_P 215_T 2.307 1.00
332_A 336_Q 2.301 1.00
200_P 217_P 2.284 1.00
132_A 168_V 2.205 1.00
81_V 113_V 2.188 1.00
74_V 84_D 2.137 1.00
69_H 86_D 2.128 1.00
99_A 130_Q 2.086 1.00
121_I 140_H 2.073 1.00
46_D 323_R 2.041 1.00
305_D 308_P 2.018 1.00
106_H 134_A 2.016 0.99
167_V 242_M 1.997 0.99
103_E 107_Q 1.945 0.99
76_E 104_K 1.929 0.99
114_A 251_S 1.904 0.99
151_A 227_S 1.903 0.99
168_V 178_L 1.878 0.99
157_D 302_P 1.859 0.99
162_T 183_T 1.844 0.99
12_L 50_I 1.834 0.99
81_V 101_G 1.83 0.99
323_R 329_P 1.817 0.99
48_H 120_H 1.811 0.99
79_A 108_H 1.771 0.98
52_M 189_G 1.771 0.98
42_L 323_R 1.733 0.98
66_Q 69_H 1.729 0.98
207_I 227_S 1.723 0.98
208_D 212_V 1.709 0.98
121_I 124_I 1.692 0.98
187_A 190_K 1.69 0.98
278_N 281_L 1.688 0.98
17_Q 31_K 1.674 0.97
21_R 27_E 1.669 0.97
186_I 205_C 1.668 0.97
136_F 279_P 1.667 0.97
78_G 104_K 1.664 0.97
20_F 53_I 1.648 0.97
321_R 325_K 1.631 0.97
179_L 238_A 1.623 0.97
208_D 219_V 1.613 0.97
33_V 89_F 1.606 0.97
101_G 111_A 1.605 0.96
201_V 205_C 1.593 0.96
41_N 46_D 1.589 0.96
101_G 113_V 1.587 0.96
138_S 168_V 1.572 0.96
34_A 38_I 1.544 0.95
120_H 189_G 1.543 0.95
151_A 207_I 1.543 0.95
100_L 103_E 1.495 0.94
157_D 301_S 1.417 0.92
149_M 188_F 1.387 0.91
131_C 276_I 1.386 0.91
14_S 18_A 1.378 0.90
17_Q 27_E 1.376 0.90
206_L 214_T 1.361 0.90
102_I 134_A 1.357 0.89
29_E 92_V 1.35 0.89
299_K 308_P 1.347 0.89
308_P 318_N 1.345 0.89
195_W 218_A 1.342 0.89
100_L 104_K 1.341 0.89
106_H 136_F 1.316 0.87
9_A 42_L 1.299 0.86
201_V 206_L 1.297 0.86
165_F 243_C 1.294 0.86
118_S 272_M 1.291 0.86
81_V 111_A 1.28 0.85
203_P 215_T 1.278 0.85
17_Q 21_R 1.278 0.85
184_S 240_A 1.263 0.84
331_D 334_S 1.261 0.84
74_V 82_T 1.261 0.84
61_S 344_Q 1.259 0.84
139_I 275_I 1.256 0.84
18_A 21_R 1.254 0.84
320_R 324_Q 1.253 0.84
30_A 34_A 1.248 0.83
100_L 113_V 1.247 0.83
69_H 88_A 1.245 0.83
165_F 239_L 1.236 0.82
150_V 183_T 1.232 0.82
99_A 103_E 1.231 0.82
80_A 282_F 1.225 0.82
169_F 242_M 1.224 0.82
36_H 91_Q 1.223 0.82
85_G 115_L 1.217 0.81
181_Y 239_L 1.21 0.81
303_H 308_P 1.205 0.80
112_A 275_I 1.198 0.80
71_A 86_D 1.189 0.79
84_D 117_N 1.188 0.79
191_T 220_M 1.185 0.79
98_M 138_S 1.181 0.78
152_P 237_Y 1.177 0.78
209_V 222_E 1.175 0.78
13_H 17_Q 1.174 0.78
194_A 201_V 1.171 0.77
77_A 281_L 1.168 0.77
35_D 126_Y 1.166 0.77
175_F 321_R 1.166 0.77
111_A 276_I 1.157 0.76
81_V 100_L 1.156 0.76
335_W 339_C 1.155 0.76
98_M 130_Q 1.153 0.76
12_L 328_I 1.153 0.76
47_S 190_K 1.147 0.75
16_I 53_I 1.143 0.75
48_H 189_G 1.137 0.75
112_A 282_F 1.134 0.74
296_E 300_A 1.131 0.74
110_I 275_I 1.128 0.74
150_V 227_S 1.123 0.73
43_A 320_R 1.123 0.73
115_L 274_T 1.116 0.73
52_M 120_H 1.114 0.72
244_E 248_G 1.112 0.72
171_R 292_E 1.109 0.72
26_E 29_E 1.099 0.71
129_E 133_A 1.094 0.70
188_F 221_Q 1.078 0.69
94_A 274_T 1.075 0.68
159_R 297_W 1.074 0.68
314_E 317_V 1.073 0.68
27_E 31_K 1.07 0.68
244_E 291_T 1.069 0.68
95_H 130_Q 1.063 0.67
292_E 295_A 1.053 0.66
98_M 276_I 1.05 0.66
173_D 292_E 1.049 0.66
32_L 95_H 1.048 0.66
143_S 253_G 1.048 0.66
19_V 57_V 1.045 0.65
101_G 131_C 1.043 0.65
26_E 68_N 1.04 0.65
81_V 104_K 1.037 0.64
167_V 243_C 1.033 0.64
98_M 102_I 1.033 0.64
112_A 273_T 1.032 0.64
150_V 184_S 1.031 0.64
102_I 105_A 1.03 0.64
310_L 318_N 1.03 0.64
293_A 297_W 1.029 0.64
50_I 330_L 1.028 0.63
56_Y 122_G 1.027 0.63
309_I 314_E 1.019 0.62
73_T 83_L 1.018 0.62
121_I 316_E 1.018 0.62
247_G 271_C 1.007 0.61
137_V 246_L 1.007 0.61
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2g8yA20.99721000.05Contact Map0.74
3i0pA10.96681000.072Contact Map0.704
1vbiA10.94181000.074Contact Map0.636
1v9nA10.95291000.075Contact Map0.706
3uoeA20.9281000.076Contact Map0.714
1rfmA80.94461000.079Contact Map0.796
1z2iA40.95571000.079Contact Map0.728
4h8aA20.92521000.082Contact Map0.744
1nxuA20.91691000.085Contact Map0.755
1wtjA20.92521000.092Contact Map0.721
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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