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OPENSEQ.org
YBIB - Uncharacterized protein YbiB
UniProt: P30177 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11580
Length: 320 (309)
Sequences: 1992
Seq/Len: 6.45
YBIB
Paralog alert: 0.33 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
234_A 240_P 3.446 1.00
9_E 24_T 3.167 1.00
280_R 285_S 3.165 1.00
22_R 64_E 3.162 1.00
19_D 52_K 3.121 1.00
148_L 154_V 2.854 1.00
270_D 273_T 2.723 1.00
234_A 298_C 2.698 1.00
100_L 278_I 2.657 1.00
38_P 174_R 2.532 1.00
44_G 47_I 2.398 1.00
104_L 292_L 2.381 1.00
208_I 243_N 2.351 1.00
146_A 150_E 2.329 1.00
257_Q 263_E 2.316 1.00
26_R 64_E 2.3 1.00
268_A 274_T 2.256 1.00
30_A 69_H 2.235 1.00
144_A 154_V 2.227 1.00
293_K 317_N 2.185 1.00
28_L 45_V 2.11 1.00
276_Q 280_R 2.065 1.00
26_R 68_N 2.039 1.00
209_G 252_V 2.032 1.00
105_L 110_F 2.015 1.00
38_P 41_E 1.99 1.00
216_S 245_I 1.989 1.00
86_P 198_R 1.922 1.00
60_L 217_D 1.921 1.00
61_G 65_A 1.914 1.00
30_A 68_N 1.87 1.00
255_E 259_T 1.856 1.00
21_D 24_T 1.827 1.00
47_I 177_V 1.823 1.00
140_H 143_Q 1.81 1.00
101_L 296_M 1.774 1.00
209_G 213_K 1.772 1.00
25_A 62_F 1.763 1.00
255_E 258_D 1.727 1.00
22_R 61_G 1.724 1.00
223_L 302_A 1.723 1.00
223_L 298_C 1.722 1.00
34_N 69_H 1.712 1.00
32_M 42_L 1.71 1.00
139_L 143_Q 1.688 1.00
222_A 245_I 1.688 1.00
308_T 311_D 1.685 1.00
97_L 291_S 1.649 1.00
133_M 275_A 1.648 1.00
66_M 188_A 1.644 1.00
108_L 300_L 1.633 1.00
229_E 238_R 1.614 1.00
255_E 263_E 1.609 1.00
215_F 222_A 1.608 1.00
256_K 260_A 1.602 1.00
297_A 312_G 1.6 1.00
62_F 180_S 1.585 1.00
132_L 272_E 1.579 0.99
30_A 65_A 1.53 0.99
305_E 315_R 1.528 0.99
287_P 290_E 1.508 0.99
228_T 238_R 1.499 0.99
37_V 42_L 1.489 0.99
306_A 312_G 1.485 0.99
269_K 274_T 1.481 0.99
50_R 54_E 1.472 0.99
39_D 174_R 1.468 0.99
87_S 90_G 1.454 0.99
12_R 18_R 1.454 0.99
110_F 300_L 1.452 0.99
205_P 241_Q 1.451 0.99
105_L 299_C 1.447 0.99
192_A 195_E 1.442 0.99
41_E 174_R 1.407 0.99
56_E 214_F 1.407 0.99
47_I 51_I 1.397 0.98
228_T 241_Q 1.376 0.98
196_A 220_G 1.36 0.98
84_V 88_Y 1.353 0.98
297_A 301_V 1.349 0.98
129_I 275_A 1.348 0.98
84_V 87_S 1.345 0.98
314_A 317_N 1.345 0.98
213_K 216_S 1.34 0.98
235_N 238_R 1.335 0.98
145_Q 149_D 1.331 0.98
256_K 261_G 1.328 0.98
118_S 128_T 1.326 0.98
254_Y 260_A 1.324 0.98
307_A 311_D 1.316 0.97
28_L 37_V 1.307 0.97
22_R 217_D 1.307 0.97
168_Q 171_M 1.304 0.97
227_G 238_R 1.298 0.97
165_L 168_Q 1.297 0.97
221_R 246_D 1.293 0.97
183_T 207_Y 1.29 0.97
244_L 301_V 1.288 0.97
139_L 147_K 1.274 0.97
84_V 90_G 1.272 0.97
255_E 260_A 1.267 0.97
279_E 283_A 1.263 0.97
43_G 171_M 1.257 0.96
221_R 244_L 1.256 0.96
40_L 174_R 1.251 0.96
57_A 217_D 1.238 0.96
91_A 253_L 1.234 0.96
256_K 259_T 1.23 0.96
9_E 18_R 1.226 0.96
40_L 171_M 1.223 0.96
31_H 36_E 1.219 0.96
254_Y 259_T 1.218 0.96
243_N 250_M 1.216 0.95
110_F 305_E 1.205 0.95
143_Q 146_A 1.194 0.95
86_P 90_G 1.194 0.95
29_Y 62_F 1.191 0.95
129_I 278_I 1.177 0.94
100_L 281_C 1.171 0.94
236_P 291_S 1.171 0.94
6_I 28_L 1.166 0.94
120_D 159_G 1.161 0.94
74_T 145_Q 1.158 0.94
254_Y 261_G 1.157 0.94
103_I 153_P 1.154 0.94
72_K 192_A 1.148 0.93
234_A 294_I 1.141 0.93
56_E 60_L 1.141 0.93
85_I 198_R 1.139 0.93
25_A 61_G 1.138 0.93
105_L 112_V 1.132 0.93
127_E 157_P 1.124 0.92
94_Q 231_E 1.117 0.92
54_E 59_M 1.116 0.92
301_V 306_A 1.113 0.92
297_A 313_L 1.109 0.92
33_L 66_M 1.106 0.92
37_V 41_E 1.099 0.91
92_R 231_E 1.098 0.91
123_R 270_D 1.093 0.91
281_C 292_L 1.09 0.91
293_K 313_L 1.089 0.91
42_L 171_M 1.087 0.91
144_A 148_L 1.084 0.90
40_L 43_G 1.08 0.90
65_A 69_H 1.079 0.90
39_D 167_K 1.071 0.90
66_M 165_L 1.07 0.90
95_A 277_W 1.069 0.90
59_M 214_F 1.063 0.89
242_I 253_L 1.059 0.89
118_S 131_E 1.059 0.89
11_G 47_I 1.052 0.89
101_L 105_L 1.049 0.88
26_R 65_A 1.048 0.88
11_G 177_V 1.046 0.88
144_A 161_F 1.044 0.88
80_P 91_A 1.035 0.88
105_L 111_P 1.03 0.87
30_A 34_N 1.03 0.87
44_G 175_M 1.03 0.87
42_L 168_Q 1.022 0.87
3_Y 28_L 1.021 0.87
135_I 153_P 1.017 0.86
52_K 58_E 1.017 0.86
85_I 101_L 1.007 0.86
20_L 58_E 1.002 0.85
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4giuA20.97811000.081Contact Map0.705
3r88A20.97811000.082Contact Map0.704
1khdA40.96881000.088Contact Map0.79
4hkmA20.97811000.088Contact Map0.787
1vquA20.97191000.09Contact Map0.767
4gtnA10.9751000.092Contact Map0.745
1o17A40.96561000.097Contact Map0.84
2elcA40.95311000.12Contact Map0.788
4eadA10.90311000.299Contact Map0.503
3h5qA10.87191000.318Contact Map0.537
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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