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OPENSEQ.org
YCEH - UPF0502 protein YceH
UniProt: P29217 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11537
Length: 215 (214)
Sequences: 254
Seq/Len: 1.19
YCEH
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
191_R 196_E 4.979 1.00
198_E 203_K 4.014 1.00
15_C 37_A 3.293 1.00
30_S 78_V 2.664 1.00
105_T 121_A 2.087 0.98
185_D 189_Q 2.071 0.98
10_A 107_L 2.029 0.97
10_A 168_S 1.981 0.97
42_T 69_R 1.948 0.96
150_V 171_V 1.871 0.95
29_L 33_G 1.864 0.95
137_L 149_V 1.813 0.94
25_E 150_V 1.739 0.92
122_A 126_E 1.694 0.90
25_E 169_G 1.547 0.84
33_G 36_T 1.51 0.82
188_L 192_V 1.494 0.81
54_E 102_L 1.481 0.80
43_N 105_T 1.461 0.79
185_D 188_L 1.451 0.78
9_E 65_R 1.451 0.78
196_E 209_L 1.448 0.78
25_E 59_L 1.446 0.78
95_L 102_L 1.41 0.75
185_D 199_V 1.399 0.74
205_R 210_L 1.393 0.74
34_V 83_Q 1.371 0.72
102_L 117_L 1.364 0.72
129_D 143_R 1.354 0.71
52_E 78_V 1.353 0.71
150_V 169_G 1.327 0.69
65_R 71_V 1.317 0.68
9_E 61_N 1.317 0.68
31_V 34_V 1.31 0.67
99_E 136_T 1.299 0.66
98_A 125_Y 1.279 0.65
51_S 54_E 1.277 0.64
78_V 101_A 1.277 0.64
15_C 107_L 1.268 0.64
103_I 156_P 1.264 0.63
209_L 213_L 1.263 0.63
69_R 82_E 1.257 0.63
34_V 38_C 1.249 0.62
191_R 209_L 1.24 0.61
157_G 160_E 1.204 0.58
35_V 55_V 1.198 0.57
180_M 183_A 1.187 0.56
166_L 192_V 1.178 0.55
86_C 158_K 1.177 0.55
13_I 89_E 1.173 0.55
20_Q 205_R 1.171 0.54
121_A 124_M 1.157 0.53
206_L 209_L 1.152 0.53
42_T 76_N 1.15 0.52
84_R 120_R 1.14 0.51
30_S 36_T 1.14 0.51
111_A 146_G 1.138 0.51
59_L 151_R 1.138 0.51
20_Q 82_E 1.128 0.50
179_D 197_I 1.123 0.50
164_M 169_G 1.121 0.50
121_A 125_Y 1.12 0.49
15_C 96_S 1.119 0.49
30_S 33_G 1.112 0.49
150_V 164_M 1.112 0.49
185_D 196_E 1.098 0.47
14_G 55_V 1.098 0.47
5_L 154_R 1.094 0.47
82_E 88_S 1.091 0.47
106_L 166_L 1.088 0.46
165_H 169_G 1.074 0.45
66_H 88_S 1.069 0.45
183_A 214_G 1.068 0.44
73_G 167_F 1.063 0.44
95_L 148_F 1.06 0.44
177_V 184_V 1.059 0.44
189_Q 214_G 1.058 0.44
59_L 70_T 1.055 0.43
33_G 197_I 1.054 0.43
47_V 133_V 1.051 0.43
197_I 201_E 1.05 0.43
23_T 26_Q 1.046 0.42
97_A 125_Y 1.044 0.42
97_A 163_Y 1.041 0.42
192_V 198_E 1.036 0.41
17_L 75_G 1.034 0.41
199_V 206_L 1.029 0.41
34_V 124_M 1.028 0.41
41_K 93_L 1.026 0.40
9_E 98_A 1.024 0.40
29_L 58_Q 1.024 0.40
5_L 130_M 1.024 0.40
96_S 132_E 1.021 0.40
85_F 114_P 1.014 0.39
187_D 197_I 1.013 0.39
208_S 212_H 1.012 0.39
20_Q 165_H 1.009 0.39
45_E 84_R 1.002 0.38
37_A 139_Q 1 0.38
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2nr3A10.77211000.164Contact Map0.406
1p4xA10.790788.10.945Contact Map0.364
2k4bA10.3302880.945Contact Map0.499
1okrA20.534983.10.948Contact Map0.646
2p4wA20.576779.80.95Contact Map0.45
3qphA10.534979.50.95Contact Map0.016
2cfxA80.637278.90.95Contact Map0.289
1sd4A20.5256780.951Contact Map0.657
1p6rA10.372176.20.952Contact Map0.684
4g9yA10.562876.20.952Contact Map0.582
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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